MCID: PRL006
MIFTS: 19

Paralytic Lagophthalmos

Categories: Eye diseases

Aliases & Classifications for Paralytic Lagophthalmos

MalaCards integrated aliases for Paralytic Lagophthalmos:

Name: Paralytic Lagophthalmos 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:12958
ICD10 33 H02.23
ICD9CM 35 374.21
SNOMED-CT 68 59890007
UMLS 73 C0155197

Summaries for Paralytic Lagophthalmos

MalaCards based summary : Paralytic Lagophthalmos is related to lagophthalmos and ectropion. An important gene associated with Paralytic Lagophthalmos is ATP6AP2 (ATPase H+ Transporting Accessory Protein 2). Affiliated tissues include eye, and related phenotypes are cardiovascular system and renal/urinary system

Related Diseases for Paralytic Lagophthalmos

Diseases related to Paralytic Lagophthalmos via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 lagophthalmos 11.0
2 ectropion 10.3
3 lepromatous leprosy 10.1
4 facial paralysis 10.1

Comorbidity relations with Paralytic Lagophthalmos via Phenotypic Disease Network (PDN):


Facial Paralysis

Symptoms & Phenotypes for Paralytic Lagophthalmos

MGI Mouse Phenotypes related to Paralytic Lagophthalmos:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.13 ATP6AP2 FGFR2 LYZ
2 renal/urinary system MP:0005367 8.8 ATP6AP2 FGFR2 LYZ

Drugs & Therapeutics for Paralytic Lagophthalmos

Search Clinical Trials , NIH Clinical Center for Paralytic Lagophthalmos

Genetic Tests for Paralytic Lagophthalmos

Anatomical Context for Paralytic Lagophthalmos

MalaCards organs/tissues related to Paralytic Lagophthalmos:

41
Eye

Publications for Paralytic Lagophthalmos

Articles related to Paralytic Lagophthalmos:

(show top 50) (show all 51)
# Title Authors Year
1
Upper eyelid platinum weight placement for the treatment of paralytic lagophthalmos: A new plane between the inner septum and the levator aponeurosis. ( 29788690 )
2018
2
Septal chondromucosal grafts in paralytic lagophthalmos. ( 30007536 )
2018
3
Transitioning from a gold weight to an "enhanced" palpebral spring in the management of paralytic lagophthalmos secondary to facial nerve palsy. ( 30047813 )
2018
4
Upper eyelid platinum weight placement for the treatment of paralytic lagophthalmos: A new plane between the inner septum and the levator aponeurosis. ( 30466243 )
2018
5
Response to Letter: Upper eyelid platinum weight placement for the treatment of paralytic lagophthalmos: A new plane between the inner septum and the levator aponeurosis. ( 30466244 )
2018
6
Levator lengthening technique using cartilage or fascia graft for paralytic lagophthalmos in facial paralysis. ( 26952126 )
2016
7
Postseptal Weight Placement for Paralytic Lagophthalmos. ( 27408667 )
2016
8
Application of Palpebral Spring in Asian Patients With Paralytic Lagophthalmos. ( 27564389 )
2016
9
Spontaneous Blinking Kinetics on Paralytic Lagophthalmos After Lid Load with Gold Weight or Autogenous Temporalis Fascia Sling. ( 26016510 )
2015
10
Treatment of the periocular complex in paralytic lagophthalmos. ( 25480756 )
2015
11
Recession and Extirpation of the Lower Eyelid Retractors for Paralytic Lagophthalmos. ( 26020720 )
2015
12
Reply: upper eyelid postseptal weight placement for treatment of paralytic lagophthalmos. ( 24374702 )
2014
13
Upper eyelid postseptal weight placement for treatment of paralytic lagophthalmos. ( 24374701 )
2014
14
Upper eyelid platinum chain placement for treating paralytic lagophthalmos. ( 25458343 )
2014
15
Hyaluronic acid gel weight: A nonsurgical option for the management of paralytic lagophthalmos. ( 24122715 )
2013
16
Alternative surgical treatment of paralytic lagophthalmos using autogenic cartilage grafts and canthopexy. ( 23728241 )
2013
17
Upper eyelid postseptal weight placement for treatment of paralytic lagophthalmos. ( 23714789 )
2013
18
Correction of paralytic lagophthalmos. ( 22908827 )
2012
19
Covering the gold weight with fascia lata graft in paralytic lagophthalmos patients. ( 21680067 )
2012
20
Paul Tessier's technique in the treatment of paralytic lagophthalmos by lengthening of the levator muscle: evaluation of 29 cases. ( 22123547 )
2011
21
Gold weight implantation as a treatment measure for correction of paralytic lagophthalmos. ( 21525707 )
2011
22
Lid loading for treatment of paralytic lagophthalmos. ( 21556983 )
2011
23
Treatment of paralytic lagophthalmos with gold weight implants covered by levator aponeurosis. ( 20489557 )
2010
24
Retrospective outcome analysis of temporalis muscle transfer for the treatment of paralytic lagophthalmos. ( 18639511 )
2009
25
Suspension of the lower lid in paralytic lagophthalmos. ( 19407643 )
2009
26
Gold weight implants in the management of paralytic lagophthalmos. ( 19406616 )
2009
27
Use of hyaluronic Acid gel in the management of paralytic lagophthalmos: the hyaluronic Acid gel "gold weight". ( 19273918 )
2009
28
Surgical treatment of bilateral paralytic lagophthalmos using scapha graft in a case of lepromatous leprosy. ( 20306645 )
2009
29
Treatment of paralytic lagophthalmos with gold weight implants covered by levator aponeurosis. ( 19454928 )
2009
30
Experience with the gold weight and palpebral spring in the management of paralytic lagophthalmos. ( 18317130 )
2008
31
Customized gold weight eyelid implantation in paralytic lagophthalmos. ( 18312710 )
2008
32
Encasement of a gold weight with dermal fat graft in the management of paralytic lagophthalmos. ( 18349638 )
2008
33
Static treatment of paralytic lagophthalmos with autogenous tissues. ( 17694252 )
2007
34
Paralytic lagophthalmos: gold-weight implantation. ( 17044423 )
2006
35
Upper eye lid loading with autologous cartilage in paralytic lagophthalmos. ( 16772979 )
2006
36
Treatment of paralytic lagophthalmos by loading the lid with a gold plate and lateral canthopexy. ( 15259671 )
2004
37
Upper lid loading with gold weights in paralytic lagophthalmos: a modified technique to maximize the long-term functional and cosmetic success. ( 15513017 )
2004
38
Temporal galeal fascia cover of custom-made gold lid weights for correction of paralytic lagophthalmos: long-term evaluation of an improved technique. ( 11777354 )
2001
39
Survey: management of paralytic lagophthalmos and paralytic ectropion. ( 10352458 )
1999
40
Porous alloplastic material encasement of gold weights for the treatment of paralytic lagophthalmos. ( 10588248 )
1999
41
Surgical repair of paralytic lagophthalmos by medial tarsal suspension of the lower lid. ( 8949714 )
1996
42
Management of paralytic lagophthalmos with a modified gold-weight implantation technique. ( 8652457 )
1996
43
A comparison of temporal muscle transfer and lid loading in the treatment of paralytic lagophthalmos. ( 7597389 )
1995
44
Eyelid reanimation for the treatment of paralytic lagophthalmos: historical perspectives and current applications of the gold weight implant. ( 1390427 )
1992
45
An improved palpebral spring for the management of paralytic lagophthalmos. ( 2062506 )
1991
46
Leprotic paralytic lagophthalmos with ectropion and its surgical correction. ( 3443493 )
1986
47
Preliminary experience with lid magnets for paralytic lagophthalmos. ( 1070862 )
1976
48
Temporalis transplantation procedure for paralytic lagophthalmos. Some modifications. ( 5129713 )
1971
49
Temporalis transplantation for paralytic lagophthalmos. ( 5472197 )
1970
50
Transposition of temporal muscle in the correction of paralytic lagophthalmos. ( 6052459 )
1967

Variations for Paralytic Lagophthalmos

Expression for Paralytic Lagophthalmos

Search GEO for disease gene expression data for Paralytic Lagophthalmos.

Pathways for Paralytic Lagophthalmos

GO Terms for Paralytic Lagophthalmos

Biological processes related to Paralytic Lagophthalmos according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 8.96 ATP6AP2 LYZ
2 positive regulation of Wnt signaling pathway GO:0030177 8.62 ATP6AP2 FGFR2

Molecular functions related to Paralytic Lagophthalmos according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 catalytic activity GO:0003824 8.62 ATP6AP2 LYZ

Sources for Paralytic Lagophthalmos

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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