MCID: PRL013
MIFTS: 30

Paralytic Poliomyelitis

Categories: Infectious diseases, Neuronal diseases

Aliases & Classifications for Paralytic Poliomyelitis

MalaCards integrated aliases for Paralytic Poliomyelitis:

Name: Paralytic Poliomyelitis 12 15
Poliomyelitis, Paralytic 73

Classifications:



External Ids:

Disease Ontology 12 DOID:0050515
UMLS 73 C1405301

Summaries for Paralytic Poliomyelitis

Disease Ontology : 12 A poliomyelitis that results in destruction located in motor neurons of central nervous system, has material basis in Human poliovirus 1, has material basis in Human poliovirus 2, or has material basis in Human poliovirus 3, which are transmitted by ingestion of food or water contaminated with feces, or transmitted by direct contact with the oral secretions. The infection has symptom loss of reflexes, has symptom muscle spasms, and has symptom acute flaccid paralysis.

MalaCards based summary : Paralytic Poliomyelitis, also known as poliomyelitis, paralytic, is related to poliomyelitis and spinal polio. An important gene associated with Paralytic Poliomyelitis is PVR (Poliovirus Receptor). Affiliated tissues include spinal cord, bone and t cells.

Related Diseases for Paralytic Poliomyelitis

Diseases related to Paralytic Poliomyelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
# Related Disease Score Top Affiliating Genes
1 poliomyelitis 32.1 ARHGEF1 DPT PVR
2 spinal polio 11.3
3 bulbospinal polio 11.3
4 bulbar polio 11.3
5 viral infectious disease 10.3
6 pertussis 10.2
7 diphtheria 10.2
8 human immunodeficiency virus infectious disease 10.2
9 meningitis 10.2
10 tetanus 10.1
11 aseptic meningitis 10.1
12 agammaglobulinemia 10.1
13 combined t cell and b cell immunodeficiency 10.1
14 amyotrophic lateral sclerosis 1 10.0
15 multiple sclerosis 10.0
16 ataxia-telangiectasia 10.0
17 west nile virus 10.0
18 acute lymphocytic leukemia 10.0
19 common variable immunodeficiency 10.0
20 leukemia 10.0
21 severe combined immunodeficiency 10.0
22 spinal cord injury 10.0
23 restless legs syndrome 10.0
24 osteomyelitis 10.0
25 mumps 10.0
26 lymphocytic leukemia 10.0
27 respiratory failure 10.0
28 acute cystitis 10.0
29 lateral sclerosis 10.0
30 syringomyelia 10.0
31 myocarditis 10.0
32 hansen's disease 10.0
33 enterocele 9.9 ARHGEF1 PVR
34 prolapse of female genital organ 9.8 ARHGEF1 PVR

Graphical network of the top 20 diseases related to Paralytic Poliomyelitis:



Diseases related to Paralytic Poliomyelitis

Symptoms & Phenotypes for Paralytic Poliomyelitis

Drugs & Therapeutics for Paralytic Poliomyelitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of Mental Fatigue in Polio Survivors Unknown status NCT00487487

Search NIH Clinical Center for Paralytic Poliomyelitis

Genetic Tests for Paralytic Poliomyelitis

Anatomical Context for Paralytic Poliomyelitis

MalaCards organs/tissues related to Paralytic Poliomyelitis:

41
Spinal Cord, Bone, T Cells, B Cells

Publications for Paralytic Poliomyelitis

Articles related to Paralytic Poliomyelitis:

(show top 50) (show all 370)
# Title Authors Year
1
Vaccine-associated paralytic poliomyelitis in a patient with acute lymphocytic leukemia. ( 29322435 )
2018
2
Recipient vaccine-associated paralytic poliomyelitis in China, 2010-2015. ( 29395524 )
2018
3
On reducing the risk of vaccine-associated paralytic poliomyelitis in the global transition from oral to inactivated poliovirus vaccine. ( 29605427 )
2018
4
Vaccine-associated paralytic poliomyelitis in the Russian Federation in 1998-2014. ( 30201507 )
2018
5
Pediatric HIV Infection and Decreased Prevalence of OPV Point Mutations Linked to Vaccine-associated Paralytic Poliomyelitis. ( 30376083 )
2018
6
Introduction of Inactivated Poliovirus Vaccine and Impact on Vaccine-Associated Paralytic Poliomyelitis - Beijing, China, 2014-2016. ( 29240729 )
2017
7
Vaccine Associated Paralytic Poliomyelitis Unmasking Common Variable Immunodeficiency. ( 28361789 )
2017
8
Pathogenic Events in a Nonhuman Primate Model of Oral Poliovirus Infection Leading to Paralytic Poliomyelitis. ( 28356537 )
2017
9
A cluster of paralytic poliomyelitis cases due to transmission of slightly diverged Sabin-2 vaccine virus. ( 27099315 )
2016
10
[VACCINE-ASSOCIATED PARALYTIC POLIOMYELITIS IN RUSSIAN FEDERATION DURING THE PERIOD OF CHANGES IN VACCINATION SCHEDULE (2006-2013 yy.)]. ( 27145594 )
2016
11
Vaccine associated paralytic poliomyelitis cases from children presenting with acute flaccid paralysis in Uganda. ( 26058454 )
2015
12
Vaccine-associated paralytic poliomyelitis: a case report. ( 24647260 )
2014
13
Outbreaks of paralytic poliomyelitis during 1996-2012: the changing epidemiology of a disease in the final stages of eradication. ( 25316846 )
2014
14
Vaccine-associated paralytic poliomyelitis and BCG-osis in an immigrant child with severe combined immunodeficiency syndrome - Texas, 2013. ( 25144542 )
2014
15
Effectiveness of oral polio vaccination against paralytic poliomyelitis: a matched case-control study in somalia. ( 25316835 )
2014
16
Vaccine-associated paralytic poliomyelitis: a review of the epidemiology and estimation of the global burden. ( 25316859 )
2014
17
Vaccine-associated paralytic poliomyelitis in the postelimination era in Latin America and the Caribbean, 1992-2011. ( 24520126 )
2014
18
Examination of motor unit control properties of the vastus lateralis in an individual that had acute paralytic poliomyelitis. ( 25083857 )
2014
19
Circadian variation of fatigue in paralytic poliomyelitis and postpolio syndrome: just fatigue or masked restless legs syndrome? ( 24964120 )
2014
20
An unusual case of vaccine-associated paralytic poliomyelitis. ( 25285130 )
2014
21
Circadian variation of fatigue in both patients with paralytic poliomyelitis and post-polio syndrome. ( 23857622 )
2013
22
Combined immunodeficiency presenting with vaccine-associated paralytic poliomyelitis: a case report and narrative review of literature. ( 24294834 )
2013
23
Children with paralytic poliomyelitis: utilization of physiotherapy services in Zamfara State, Nigeria. ( 22871225 )
2013
24
Children with paralytic poliomyelitis: a cross-sectional study of knowledge, attitudes and beliefs of parents in Zamfara state, Nigeria. ( 23083466 )
2012
25
Risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis. ( 22827246 )
2012
26
Vaccine-associated paralytic poliomyelitis in Japan. ( 22325660 )
2012
27
Apropos risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis. ( 23249227 )
2012
28
Paralytic poliomyelitis associated with Sabin monovalent and bivalent oral polio vaccines in Hungary. ( 21685412 )
2011
29
Molecular characterization of poliovirus isolates from children who contracted vaccine-associated paralytic poliomyelitis (VAPP) following administration of monovalent type 3 oral poliovirus vaccine in the 1960s in Hungary. ( 19863665 )
2010
30
MR finding in vaccine-associated paralytic poliomyelitis. ( 20567967 )
2010
31
Vaccine-associated paralytic poliomyelitis in immunodeficient children, Iran, 1995-2008. ( 20587188 )
2010
32
A case of paralytic poliomyelitis associated with poliovirus vaccine strains in Hokkaido, Japan. ( 20495280 )
2010
33
Vaccine-associated paralytic poliomyelitis in an infant with perianal abscesses. ( 20449625 )
2010
34
Vaccine-associated paralytic poliomyelitis in a non-immunocompromised infant. ( 20880307 )
2010
35
MRI findings in an infant with vaccine-associated paralytic poliomyelitis. ( 20440488 )
2010
36
Three cases of paralytic poliomyelitis associated with type 3 vaccine poliovirus strains in Bulgaria. ( 19626606 )
2009
37
Ala67Thr mutation in the poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis. ( 19319949 )
2009
38
Effectiveness of immunization against paralytic poliomyelitis in Nigeria. ( 18923171 )
2008
39
Poisson-model analysis of the risk of vaccine-associated paralytic poliomyelitis in Japan between 1971 and 2000. ( 18362395 )
2008
40
Vaccine-associated paralytic poliomyelitis in a pre-vaccinated infant. ( 18998027 )
2008
41
Vaccine - associated paralytic poliomyelitis in a pre-vaccinated infant. ( 18626544 )
2008
42
Paralytic poliomyelitis during the pre-, peri- and post-suspension periods of a polio immunization campaign. ( 18628551 )
2008
43
Novel BTK mutation presenting with vaccine-associated paralytic poliomyelitis. ( 18317803 )
2008
44
[Paralytic poliomyelitis in Russian Federation in 1998-2005]. ( 18038545 )
2007
45
Characterization of mutations in the VP(1) region of Sabin strain type 1 polioviruses isolated from vaccine-associated paralytic poliomyelitis cases in Iran. ( 17590391 )
2007
46
Vaccine-associated paralytic poliomyelitis in a patient with MHC class II deficiency. ( 17509935 )
2007
47
Vaccine-associated paralytic poliomyelitis: a case report of flaccid monoparesis after oral polio vaccine. ( 17449951 )
2007
48
Imported vaccine-associated paralytic poliomyelitis--United States, 2005. ( 16456525 )
2006
49
No evidence for prolonged excretion of polioviruses in persons with residual paralytic poliomyelitis in Ethiopia, Pakistan and Guatemala. ( 16682222 )
2006
50
[Cellular and humoral immunodeficiency in children with vaccine-associated paralytic poliomyelitis]. ( 17297880 )
2006

Variations for Paralytic Poliomyelitis

Expression for Paralytic Poliomyelitis

Search GEO for disease gene expression data for Paralytic Poliomyelitis.

Pathways for Paralytic Poliomyelitis

GO Terms for Paralytic Poliomyelitis

Biological processes related to Paralytic Poliomyelitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 8.8 DPT NID1 PVR

Molecular functions related to Paralytic Poliomyelitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 8.62 DPT NID1

Sources for Paralytic Poliomyelitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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