MCID: PRL014
MIFTS: 27

Paralytic Squint

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Paralytic Squint

MalaCards integrated aliases for Paralytic Squint:

Name: Paralytic Squint 12 15
Paralytic Strabismus 12 17 74
Incomitant Dissociation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10863
ICD9CM 36 378.5 378.50
SNOMED-CT 69 12942001
ICD10 34 H49 H49.9
UMLS 74 C0152221

Summaries for Paralytic Squint

MalaCards based summary : Paralytic Squint, also known as paralytic strabismus, is related to strabismus and fourth cranial nerve palsy. An important gene associated with Paralytic Squint is CHN1 (Chimerin 1). The drugs Acetylcholine and Peripheral Nervous System Agents have been mentioned in the context of this disorder. Affiliated tissues include eye and testes.

Wikipedia : 77 Strabismus is a condition in which the eyes do not properly align with each other when looking at an... more...

Related Diseases for Paralytic Squint

Diseases related to Paralytic Squint via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 strabismus 30.6 CHN1 KIF21A PHOX2A
2 fourth cranial nerve palsy 30.4 CHN1 RANBP2
3 kearns-sayre syndrome 30.1 KIF21A PHOX2A
4 tukel syndrome 29.4 CHN1 KIF21A PHOX2A TUBB2B
5 mechanical strabismus 10.7
6 abducens nerve disease 10.7
7 tolosa-hunt syndrome 10.4
8 fourth cranial nerve palsy, familial congenital 10.2
9 progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 1 10.2
10 gaze palsy, familial horizontal, with progressive scoliosis, 1 10.2
11 total third-nerve palsy 10.2
12 oculomotor nerve paralysis 10.2
13 chronic progressive external ophthalmoplegia 10.2
14 trochlear nerve disease 10.2
15 autosomal dominant progressive external ophthalmoplegia 10.2
16 mitochondrial dna-related progressive external ophthalmoplegia 10.2
17 congenital trochlear nerve palsy 10.2
18 lyme disease 10.1
19 dengue virus 10.1
20 dengue disease 10.1
21 congenital ptosis 10.0 CHN1 KIF21A
22 keratopathy 10.0
23 thrombosis 10.0
24 monocular esotropia 10.0
25 blepharospasm 10.0
26 esotropia 10.0
27 hypertropia 10.0 CHN1 KIF21A
28 deafness, autosomal dominant 28 9.9 CHN1 KIF21A
29 duane retraction syndrome 9.9 CHN1 KIF21A
30 fibrosis of extraocular muscles, congenital, 2 9.8 KIF21A PHOX2A
31 ptosis 9.8 KIF21A PHOX2A
32 facial nerve disease 9.8 KIF21A PHOX2A
33 amblyopia 9.7 CHN1 PHOX2A
34 peripheral nervous system disease 9.7 CHN1 KIF21A
35 exotropia 9.6 CHN1 KIF21A PHOX2A
36 hypotropia 9.6 CHN1 KIF21A PHOX2A
37 ocular motility disease 9.6 CHN1 KIF21A PHOX2A
38 cranial nerve disease 9.6 CHN1 KIF21A PHOX2A

Graphical network of the top 20 diseases related to Paralytic Squint:



Diseases related to Paralytic Squint

Symptoms & Phenotypes for Paralytic Squint

Drugs & Therapeutics for Paralytic Squint

Drugs for Paralytic Squint (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 3 51-84-3 187
2 Peripheral Nervous System Agents Phase 3
3 abobotulinumtoxinA Phase 3
4 Botulinum Toxins Phase 3
5 Neuromuscular Agents Phase 3
6 Acetylcholine Release Inhibitors Phase 3
7 Cholinergic Agents Phase 3
8 Neurotransmitter Agents Phase 3
9 Botulinum Toxins, Type A Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Efficacy and Safety of GSK1358820 (Botulinum Toxin Type A) in Patients With Strabismus Completed NCT01584843 Phase 3 GSK1358820

Search NIH Clinical Center for Paralytic Squint

Genetic Tests for Paralytic Squint

Anatomical Context for Paralytic Squint

MalaCards organs/tissues related to Paralytic Squint:

42
Eye, Testes

Publications for Paralytic Squint

Articles related to Paralytic Squint:

(show top 50) (show all 57)
# Title Authors Year
1
Muscle Union Procedure in Patients with Paralytic Strabismus. ( 26070148 )
2015
2
The Role of Extraocular Muscle Pulleys in Incomitant Non-Paralytic Strabismus. ( 26180464 )
2015
3
Paralytic strabismus and papilloedema caused by dural sinus thrombosis after bee sting. ( 25234425 )
2014
4
Acquired paralytic strabismus in Southern Taiwan. ( 23608076 )
2013
5
Paralytic strabismus in South African Black and mixed race children--a 15-year clinic-based review. ( 23171209 )
2012
6
Paralytic squint due to abducens nerve palsy: a rare consequence of dengue fever. ( 22799448 )
2012
7
Paralytic strabismus: third, fourth, and sixth nerve palsy. ( 20638001 )
2010
8
Five cases of paralytic strabismus as a rare feature of lyme disease. ( 19193112 )
2009
9
General principles in the surgical treatment of paralytic strabismus. ( 21149177 )
2008
10
Filamentary keratopathy caused by corneal occlusion by large-angle paralytic strabismus. ( 17133065 )
2006
11
Suture fixation system as globe tethers in severe paralytic strabismus. ( 16935240 )
2006
12
Unilateral paralytic strabismus in the adult cat induces plastic changes in interocular disparity along the visual midline: contribution of the corpus callosum. ( 16079008 )
2005
13
Effect of full tendon transposition augmented with posterior intermuscular suture for paralytic strabismus. ( 16084787 )
2005
14
Paralytic strabismus as a manifestation of lyme borreliosis. ( 16193697 )
2005
15
Clinical observation on treatment of acquired paralytic strabismus by acupuncture plus oral administration of Chinese herbs. ( 14535181 )
2003
16
Rectus extraocular muscle pulley displacement after surgical transposition and posterior fixation for treatment of paralytic strabismus. ( 11755847 )
2002
17
Paralytic strabismus. ( 11588500 )
2001
18
Split rectus muscle modified Foster procedure for paralytic strabismus: a report of 5 cases. ( 11720594 )
2001
19
Strabismus surgery in the treatment of paralytic strabismus. ( 11734680 )
2001
20
Augmented Hummelsheim procedure for paralytic strabismus. ( 10955540 )
2000
21
Paralytic strabismus. ( 11148696 )
2000
22
Paralytic strabismus. ( 10621543 )
1999
23
The surgical correction of paralytic strabismus using fascia lata. ( 9503312 )
1998
24
Paralytic strabismus. ( 10387476 )
1998
25
Paralytic strabismus. ( 10159715 )
1995
26
Quantitative magnetic resonance morphometry of extraocular muscles: a new diagnostic tool in paralytic strabismus. ( 7931952 )
1994
27
Paralytic strabismus and syndromes. ( 10150809 )
1994
28
Botulinum toxin in the treatment of paralytic strabismus and essential blepharospasm. ( 8125543 )
1993
29
81 cases of paralytic strabismus treated with acupuncture. ( 8412281 )
1993
30
Saccadic velocity studies in paralytic strabismus: fixation with the paretic vs the nonparetic eye. ( 3977216 )
1985
31
Paralytic strabismus: the role of botulinum toxin. ( 4084480 )
1985
32
Paralytic squint treated with acupuncture. ( 6570146 )
1984
33
Paralytic strabismus correction by adjustable suture technique. ( 6370300 )
1984
34
Graphic analysis of paralytic strabismus with the Lancaster red-green test. ( 6720837 )
1984
35
Paralytic strabismus in children. Etiologic incidence and management of the third, fourth, and sixth nerve palsies. ( 7375084 )
1980
36
The use of prisms in paralytic squint. ( 900621 )
1977
37
Management of non-paralytic strabismus in infants, with special reference to esotropia. ( 836771 )
1977
38
Abnormal saccades in paralytic strabismus. ( 835653 )
1977
39
Measurement of the field of binocular single vision in the evaluation of incomitant paralytic strabismus. ( 4830090 )
1974
40
Management of paralytic strabismus. ( 4834599 )
1974
41
A surgery on twenty six thousand and three hundred seventy eight patients with convergent squint (26378), thirteen thousand, one hundred and eighty one patients with divergent squint (13181), one thousand and twenty nine patients of vertical squint (1029), ten thousand and one hundred thirty nine patients of heterophoria (10139) and two thousand sixty one patients of paralytic squint (2061) seen during the past ten years at Giza Ophthalmic Hospital Squint Clinic from the year 1960 to the year 1970. ( 4666806 )
1972
42
Diagnosis of paralytic squint. ( 5154750 )
1971
43
Past-pointing in paralytic strabismus. ( 5541186 )
1971
44
Past-pointing in paralytic strabismus. ( 5524218 )
1970
45
Operative treatment of paralytic strabismus. ( 5536726 )
1970
46
The diagnostic comparisons between congenital and acquired paralytic strabismus. ( 6035863 )
1967
47
The role of the orthoptist in the management of acquired paralytic strabismus. ( 5936924 )
1966
48
NON-PARALYTIC squint. ( 13450382 )
1957
49
Paralytic strabismus, with special reference to surgical treatment. ( 13295778 )
1955
50
Orthoptic and surgical treatment of non-paralytic strabismus. ( 13019422 )
1953

Variations for Paralytic Squint

Expression for Paralytic Squint

Search GEO for disease gene expression data for Paralytic Squint.

Pathways for Paralytic Squint

GO Terms for Paralytic Squint

Sources for Paralytic Squint

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....