Parameningeal Embryonal Rhabdomyosarcoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Parameningeal Embryonal Rhabdomyosarcoma

MalaCards integrated aliases for Parameningeal Embryonal Rhabdomyosarcoma:

Name: Parameningeal Embryonal Rhabdomyosarcoma ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases Fetal diseases
Anatomical: Muscle diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0060338

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Summaries for Parameningeal Embryonal Rhabdomyosarcoma

Disease Ontology : ¹² An embryonal rhabdomyosarcoma located in the parameningeal region.

MalaCards based summary : Parameningeal Embryonal Rhabdomyosarcoma is related to rhabdomyosarcoma and embryonal rhabdomyosarcoma. An important gene associated with Parameningeal Embryonal Rhabdomyosarcoma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Pathways in cancer and Glioma. Related phenotype is pigmentation.

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Related Diseases for Parameningeal Embryonal Rhabdomyosarcoma

Diseases related to Parameningeal Embryonal Rhabdomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)

#	Related Disease	Score	Top Affiliating Genes
1	rhabdomyosarcoma	29.9	ALK TP53
2	embryonal rhabdomyosarcoma	10.3
3	lung papillary adenocarcinoma	9.8	ALK TP53
4	pleomorphic carcinoma	9.8	ALK TP53
5	peripheral nervous system neoplasm	9.7	ALK TP53
6	autonomic nervous system neoplasm	9.7	ALK TP53
7	histiocytoma	9.7	ALK TP53
8	inflammatory myofibroblastic tumor	9.7	ALK TP53
9	peripheral t-cell lymphoma	9.7	ALK TP53
10	respiratory system cancer	9.7	ALK TP53
11	differentiated thyroid carcinoma	9.7	ALK TP53
12	cell type cancer	9.7	ALK TP53
13	diffuse large b-cell lymphoma	9.6	ALK TP53
14	lung squamous cell carcinoma	9.6	ALK TP53
15	brain cancer	9.6	ALK TP53
16	lymphoma, non-hodgkin, familial	9.6	ALK TP53
17	hematologic cancer	9.5	ALK TP53
18	adenocarcinoma	9.5	ALK TP53
19	lung cancer susceptibility 3	9.4	ALK TP53
20	glioblastoma	9.3	ALK TP53
21	neuroblastoma	9.2	ALK TP53
22	ewing sarcoma	9.0	ALK TP53

Graphical network of the top 20 diseases related to Parameningeal Embryonal Rhabdomyosarcoma:

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Symptoms & Phenotypes for Parameningeal Embryonal Rhabdomyosarcoma

MGI Mouse Phenotypes related to Parameningeal Embryonal Rhabdomyosarcoma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	pigmentation	MP:0001186	8.62	ALK TP53

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Drugs & Therapeutics for Parameningeal Embryonal Rhabdomyosarcoma

Search Clinical Trials , NIH Clinical Center for Parameningeal Embryonal Rhabdomyosarcoma

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Genetic Tests for Parameningeal Embryonal Rhabdomyosarcoma

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Anatomical Context for Parameningeal Embryonal Rhabdomyosarcoma

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Publications for Parameningeal Embryonal Rhabdomyosarcoma

Articles related to Parameningeal Embryonal Rhabdomyosarcoma:

#	Title	Authors	Year
1	A Patient-Derived Xenograft Model of Parameningeal Embryonal Rhabdomyosarcoma for Preclinical Studies. ( 26696773 )	Hooper J.E....Keller C.	2015
2	Ophthalmic involvement as a presenting feature of nonorbital childhood parameningeal embryonal rhabdomyosarcoma. ( 11150285 )	Mullaney P.B....Buncic R.	2001
3	Parameningeal embryonal rhabdomyosarcoma in an adult. ( 11225232 )	Patel A....Kumar A.	1999

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Genes for Parameningeal Embryonal Rhabdomyosarcoma

Genes related to Parameningeal Embryonal Rhabdomyosarcoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	TP53	Tumor Protein P53	Protein Coding	13.55	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	ALK	ALK Receptor Tyrosine Kinase	Protein Coding	13.5	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

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Variations for Parameningeal Embryonal Rhabdomyosarcoma

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Expression for Parameningeal Embryonal Rhabdomyosarcoma

Search GEO for disease gene expression data for Parameningeal Embryonal Rhabdomyosarcoma.

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Pathways for Parameningeal Embryonal Rhabdomyosarcoma

Pathways related to Parameningeal Embryonal Rhabdomyosarcoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Pathways in cancer ³⁷	11.68	ALK TP53
2	Glioma ³⁷ Show member pathways EGFR tyrosine kinase inhibitor resistance ³⁷ Endocrine resistance ³⁷ Melanoma ³⁷ Non-small cell lung cancer ³⁷ Signaling Pathways in Glioblastoma ¹	11.29	ALK TP53

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GO Terms for Parameningeal Embryonal Rhabdomyosarcoma

Cellular components related to Parameningeal Embryonal Rhabdomyosarcoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein-containing complex	GO:0032991	8.62	ALK TP53

Biological processes related to Parameningeal Embryonal Rhabdomyosarcoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of apoptotic process	GO:0043066	9.16	ALK TP53
2	cell proliferation	GO:0008283	8.96	ALK TP53
3	regulation of apoptotic process	GO:0042981	8.62	ALK TP53

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Sources for Parameningeal Embryonal Rhabdomyosarcoma

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⁴⁸ NCBI Bookshelf

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⁷⁶ Wikipedia