Parameningeal Embryonal Rhabdomyosarcoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Parameningeal Embryonal Rhabdomyosarcoma

MalaCards integrated aliases for Parameningeal Embryonal Rhabdomyosarcoma:

Name: Parameningeal Embryonal Rhabdomyosarcoma ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases Fetal diseases
Anatomical: Muscle diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0060338

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Summaries for Parameningeal Embryonal Rhabdomyosarcoma

Disease Ontology : ¹² An embryonal rhabdomyosarcoma located in the parameningeal region.

MalaCards based summary : Parameningeal Embryonal Rhabdomyosarcoma is related to rhabdomyosarcoma and embryonal rhabdomyosarcoma. An important gene associated with Parameningeal Embryonal Rhabdomyosarcoma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Pathways in cancer and Glioma. Related phenotype is pigmentation.

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Related Diseases for Parameningeal Embryonal Rhabdomyosarcoma

Diseases related to Parameningeal Embryonal Rhabdomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)

#	Related Disease	Score	Top Affiliating Genes
1	rhabdomyosarcoma	30.5	ALK TP53
2	embryonal rhabdomyosarcoma	10.5
3	lung papillary adenocarcinoma	9.9	ALK TP53
4	adenocarcinoma	9.9	ALK TP53
5	pleomorphic carcinoma	9.9	ALK TP53
6	autonomic nervous system neoplasm	9.8	ALK TP53
7	peripheral nervous system neoplasm	9.8	ALK TP53
8	histiocytoma	9.8	ALK TP53
9	inflammatory myofibroblastic tumor	9.8	ALK TP53
10	respiratory system cancer	9.8	ALK TP53
11	differentiated thyroid carcinoma	9.8	ALK TP53
12	respiratory system disease	9.8	ALK TP53
13	lung squamous cell carcinoma	9.8	ALK TP53
14	hematologic cancer	9.8	ALK TP53
15	lymphoma, non-hodgkin, familial	9.8	ALK TP53
16	brain cancer	9.7	ALK TP53
17	lung cancer susceptibility 3	9.7	ALK TP53
18	glioblastoma	9.7	ALK TP53
19	neuroblastoma	9.6	ALK TP53
20	ewing sarcoma	9.5	ALK TP53

Graphical network of the top 20 diseases related to Parameningeal Embryonal Rhabdomyosarcoma:

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Symptoms & Phenotypes for Parameningeal Embryonal Rhabdomyosarcoma

MGI Mouse Phenotypes related to Parameningeal Embryonal Rhabdomyosarcoma:

⁴⁷

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	pigmentation	MP:0001186	8.62	ALK TP53

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Drugs & Therapeutics for Parameningeal Embryonal Rhabdomyosarcoma

Search Clinical Trials , NIH Clinical Center for Parameningeal Embryonal Rhabdomyosarcoma

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Genetic Tests for Parameningeal Embryonal Rhabdomyosarcoma

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Anatomical Context for Parameningeal Embryonal Rhabdomyosarcoma

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Publications for Parameningeal Embryonal Rhabdomyosarcoma

Articles related to Parameningeal Embryonal Rhabdomyosarcoma:

#	Title	Authors	Year
1	A Patient-Derived Xenograft Model of Parameningeal Embryonal Rhabdomyosarcoma for Preclinical Studies. ( 26696773 )	Hooper J.E....Keller C.	2015
2	Ophthalmic involvement as a presenting feature of nonorbital childhood parameningeal embryonal rhabdomyosarcoma. ( 11150285 )	Mullaney P.B....Buncic R.	2001
3	Parameningeal embryonal rhabdomyosarcoma in an adult. ( 11225232 )	Patel A....Kumar A.	1999

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Genes for Parameningeal Embryonal Rhabdomyosarcoma

Genes related to Parameningeal Embryonal Rhabdomyosarcoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	TP53	Tumor Protein P53	Protein Coding	13.52	DISEASES inferred ¹⁵
2	ALK	ALK Receptor Tyrosine Kinase	Protein Coding	13.3	DISEASES inferred ¹⁵

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Variations for Parameningeal Embryonal Rhabdomyosarcoma

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Expression for Parameningeal Embryonal Rhabdomyosarcoma

Search GEO for disease gene expression data for Parameningeal Embryonal Rhabdomyosarcoma.

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Pathways for Parameningeal Embryonal Rhabdomyosarcoma

Pathways related to Parameningeal Embryonal Rhabdomyosarcoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Pathways in cancer ³⁸	11.68	ALK TP53
2	Glioma ³⁸ Show member pathways Endocrine resistance ³⁸ Melanoma ³⁸ Non-small cell lung cancer ³⁸ Signaling Pathways in Glioblastoma ¹	11.22	ALK TP53

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GO Terms for Parameningeal Embryonal Rhabdomyosarcoma

Cellular components related to Parameningeal Embryonal Rhabdomyosarcoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein-containing complex	GO:0032991	8.62	ALK TP53

Biological processes related to Parameningeal Embryonal Rhabdomyosarcoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cell proliferation	GO:0008283	8.96	ALK TP53
2	negative regulation of apoptotic process	GO:0043066	8.85	TP53
3	regulation of apoptotic process	GO:0042981	8.62	ALK TP53

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Sources for Parameningeal Embryonal Rhabdomyosarcoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

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⁶ ClinVar

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⁹ Cosmic

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¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

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³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

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⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

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⁵¹ NCIt

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⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

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⁵⁶ Novoseek

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⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

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⁶¹ PathCards

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⁶³ PubMed

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⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia