Categories: Infectious diseases, Reproductive diseases

Aliases & Classifications for Parametritis

MalaCards integrated aliases for Parametritis:

Name: Parametritis 12 44 15 17 70
Pelvic Cellulitis 12


External Ids:

Disease Ontology 12 DOID:1260
MeSH 44 D010249
SNOMED-CT 67 280483007
UMLS 70 C0030455

Summaries for Parametritis

MalaCards based summary : Parametritis, also known as pelvic cellulitis, is related to internal hemorrhoid and hemorrhoid. An important gene associated with Parametritis is TXNDC17 (Thioredoxin Domain Containing 17), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Folate Metabolism. The drugs Liraglutide and Hormone Antagonists have been mentioned in the context of this disorder. Affiliated tissues include prostate, liver and uterus, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 73 Parametritis, (also known as pelvic cellulitis) is an inflammation of the parametrium (connective tissue... more...

Related Diseases for Parametritis

Diseases related to Parametritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 325)
# Related Disease Score Top Affiliating Genes
1 internal hemorrhoid 30.5 F2 CRP
2 hemorrhoid 30.4 F2 CRP ALB
3 peritonitis 29.7 MPO ICAM1 F2 CRP ALB
4 cellulitis 29.4 IL5 F3 F2 CRP ALB
5 salpingitis 10.9
6 orbital osteomyelitis 10.4 F2 CRP
7 hemometra 10.4 PTPRN INSM1
8 small intestine diverticulitis 10.4 F2 CRP
9 isthmus cancer 10.4 PTPRN INSM1
10 non-a-e hepatitis 10.4 F2 ALB
11 antipyrine metabolism 10.4 F2 ALB
12 microinvasive cervical squamous cell carcinoma 10.4 PTPRN INSM1
13 hematocele of tunica vaginalis testis 10.4 F2 CRP
14 chronic duodenal ileus 10.4 CRP ALB
15 supine hypotensive syndrome 10.4 OXT F2
16 subdural empyema 10.3 F2 CRP
17 bleeding disorder, platelet-type, 17 10.3 PTPRN INSM1
18 breast abscess 10.3 OXT CRP
19 cervical incompetence 10.3 PTPRN OXT INSM1
20 peptic ulcer perforation 10.3 CRP ALB
21 ankylosing spondylitis 3 10.3 CRP ALB
22 tuberculous peritonitis 10.3 CRP ALB
23 familial lcat deficiency 10.3 APOA1 ALB
24 purulent acute otitis media 10.3 MPO CRP
25 eclampsia 10.3 OXT F2 ALB
26 chronic intestinal vascular insufficiency 10.3 CRP ALB
27 lymphocele 10.3 PTPRN INSM1 ALB
28 aspirin resistance 10.3 F2 APOB
29 meningovascular neurosyphilis 10.3 CRP ALB
30 abducens nerve disease 10.3 F2 CRP
31 multiple cranial nerve palsy 10.3 MPO CRP
32 infective endocarditis 10.3 PPBP F2 CRP
33 acalculous cholecystitis 10.3 F2 CRP ALB
34 splenic abscess 10.3 F2 CRP ALB
35 ascending cholangitis 10.3 F2 CRP ALB
36 asphyxia neonatorum 10.3 OXT CRP ALB
37 splenic tuberculosis 10.3 F2 CRP ALB
38 paralytic ileus 10.3 F2 CRP ALB
39 acute cholangitis 10.3 F2 CRP ALB
40 common bile duct disease 10.3 F2 CRP ALB
41 abdominal tuberculosis 10.3 F2 CRP ALB
42 pyuria 10.3 F2 CRP ALB
43 hydrops of gallbladder 10.3 CRP ALB
44 pleural empyema 10.3 F2 CRP ALB
45 kwashiorkor 10.3 F2 CRP ALB
46 hepatic tuberculosis 10.3 F2 CRP ALB
47 choledocholithiasis 10.3 F2 CRP ALB
48 cholesterol embolism 10.3 F2 CRP
49 glossopharyngeal nerve disease 10.3 MPO CRP
50 mitral valve insufficiency 10.2 F2 CRP ALB

Graphical network of the top 20 diseases related to Parametritis:

Diseases related to Parametritis

Symptoms & Phenotypes for Parametritis

MGI Mouse Phenotypes related to Parametritis:

# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.13 ALB APOA1 APOB CRP F2 F3
2 homeostasis/metabolism MP:0005376 10.11 ALB APCS APOA1 APOB CISH CRP
3 endocrine/exocrine gland MP:0005379 9.96 ALB APOA1 CISH F2 ICAM1 INSM1
4 immune system MP:0005387 9.77 ALB APCS APOB CISH CRP F2
5 muscle MP:0005369 9.23 ALB APOB F2 F3 ICAM1 MB

Drugs & Therapeutics for Parametritis

Drugs for Parametritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 39)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Liraglutide Approved Phase 4 204656-20-2 44147092
2 Hormone Antagonists Phase 4
3 Incretins Phase 4
4 Hypoglycemic Agents Phase 4
5 Hormones Phase 4
6 Fluorodeoxyglucose F18 Phase 4
7 Radiopharmaceuticals Phase 4
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
Topotecan Approved, Investigational Phase 2 123948-87-8, 119413-54-6 60700
10 Bombesin Investigational Phase 2 31362-50-2
11 Androgens Phase 1, Phase 2
12 topoisomerase I inhibitors Phase 2
13 Neurotransmitter Agents Phase 2
14 gastrin-releasing peptide Phase 2
Adenosine Approved, Investigational 58-61-7 60961
alemtuzumab Approved, Investigational 216503-57-0
Interferon beta-1a Approved, Investigational 145258-61-3 6438354
Chlorhexidine Approved, Vet_approved 55-56-1 2713 9552079
Metronidazole Approved 443-48-1 4173
Iron Approved 7439-89-6 23925 29936
Pancrelipase Approved, Investigational 53608-75-6
Choline Approved, Nutraceutical 62-49-7 305
Chlorotrianisene Investigational, Withdrawn 569-57-3 11289
24 Chelating Agents
25 Gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate
26 Carbon-11 methionine
27 Opiate Alkaloids Early Phase 1
28 interferons
29 Interferon-beta
30 Nutrients
31 Fluorides
32 Antibiotics, Antitubercular
33 Anti-Bacterial Agents
34 Anti-Inflammatory Agents
35 Anesthetics
36 Chlorhexidine gluconate
37 Pharmaceutical Solutions
38 pancreatin
39 Liver Extracts

Interventional clinical trials:

(show top 50) (show all 94)
# Name Status NCT ID Phase Drugs
1 Multi-parametric Imaging of the Knee in Obese Patients With Knee Osteoarthritis Following Liraglutide Treatment, Investigating the Impact on Inflammation Completed NCT02928679 Phase 4 Liraglutide 3 mg (Saxenda);Liraglutide 3 mg placebo
2 Renal Effects of Hormones/Biomarkers in Transgender PrEP Recipients Sub-Study Recruiting NCT04742816 Phase 4 Iohexol
3 Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction Enrolling by invitation NCT04417998 Phase 4 18F-FDG;18F-AV1451
4 A Randomized Control Trial of Magnetic Resonance Imaging-targeted Biopsy Compared to Standard Trans-rectal Ultrasound Guided Biopsy for the Diagnosis of Prostate Cancer in Men Without Prior Biopsy Completed NCT02380027 Phase 3
5 An Evaluation of a Novel Imaging Based Complex Diagnostic and Therapeutic Pathway Intervention for Men Who Fail Radiotherapy for Prostate Cancer. Unknown status NCT01883128 Phase 2
6 Serial mpMRI (Multi Parametric Magnetic Resonance Imaging) Scanning in Prostate Cancer After Androgen Deprivation Therapy and RadioTherapy (SMART) Unknown status NCT02721784 Phase 1, Phase 2
7 A Pilot Study of Weekly IV Topotecan and Cisplatin With Concurrent Pelvic Radiation in the Treatment of Stages IB2 - IVA Cervical Carcinoma Completed NCT00257816 Phase 2 Topotecan;Cisplatin
8 Evaluation of Patients With Low-Risk and Intermediate-Risk Prostate Cancer Scheduled for High-Dose Rate Brachytherapy Using 68-Ga-RM2 PET, 68Ga-PSMA-11 PET and Multi Parametric MRI Recruiting NCT04264208 Phase 2 68-Ga RM2.;68-Ga PSMA11
9 Breast MRI Assessment of Tumor Viability After Radiofrequency Ablation (RFA) Withdrawn NCT00373152 Phase 2
10 Parametric Testing of Direct Physiological Effects of Transcutaneous Vagus Nerve Stimulation (tVNS) in Healthy Controls Completed NCT02835885 Phase 1
11 Detection, Estimation and Characterization of Pulmonary Blood Pressure by Transthoracic Parametric Doppler (TPD) Terminated NCT01357746 Phase 1
12 Whole Body Multi---Parametric MRI: Accuracy in Staging of Biochemically Relapsed Prostate Cancer Unknown status NCT02935816
13 Multi-parametric Ultrasound Targeted Biopsies Compared to Multi-parametric MRI Targeted Biopsies in the Diagnosis of Clinically Significant Prostate Cancer Unknown status NCT02712684
14 Pathology and Imaging in Kidney Allografts Unknown status NCT03780101
15 Assessment of the Contribution of the Combined Acoustic Hearing Via a Hearing Aid and Electric Hearing Via a Cochlear Implant in Adult Bimodal Users With Moderate to Severe Residual Hearing in the Implanted and Non Implanted Ear. Unknown status NCT02331017
16 Study of the Interest of the Parametric Imaging in Positron Emission Tomography on the Recurrence Prognosis at One Year in Patient With Non Small Cell Lung Cancer Unknown status NCT02821936
17 Characterizing Sleep Disorders in Children and Adults With Tuberous Sclerosis Complex (TSC) Unknown status NCT03326765
18 Phase II Study of Focused Dose Painted I-125 Brachytherapy for Low to Intermediate Risk Prostate Cancer Using Deformable Registration of Multi-parametric MRI (Magnetic Resonance Imaging) to Intra-operative TRUS (Trans Rectal Ultrasound) Unknown status NCT02790216
19 PICTURE - Prostate Imaging (Multi-parametric MRI and Prostate HistoScanning™) Compared to Transperineal Ultrasound Guided Biopsy for Significant Prostate Cancer Risk Evaluation. Unknown status NCT01492270
20 Evaluation of the Added Value of PSMA-PET Compared With Multi-parametric MRI in the Detection and Classification of Prostate Lesions Unknown status NCT03174054
21 PROMIS - Prostate MRI Imaging Study - Evaluation of Multi-Parametric Magnetic Resonance Imaging in the Diagnosis and Characterization of Prostate Cancer Unknown status NCT01292291
22 Quantitative and Multi-Parametric 3D Magnetic Resonance Imaging of Primary Brain Tumors Unknown status NCT02649699
23 A Phase III Multi-centre Open-label Randomized Controlled Trial of Multi-parametric Magnetic Resonance Imaging (MRI)-Targeted Biopsy Compared to Systematic Trans-rectal Ultrasound (TRUS) Guided Biopsy Unknown status NCT02936258
24 A Prospective Study: the Value of Using Parametric Color Coding of Digital Subtraction Angiography and Flat-panel Detector Computed Tomography Parenchymal Blood Volume Imaging in the Endovascular Treatment of Infrapopliteal Arterial Occlusive Diseases Unknown status NCT03248323
25 Development of a New Generation Multi Parametric Test for Prediction of Colorectal Neoplasia Recurrence Unknown status NCT03434925
26 Usefulness of Multi-parametric, Quantitative MR Imaging for Staging of Hepatic Fibrosis in the Patients With Chronic Hepatitis Unknown status NCT01981421
27 Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application Completed NCT03554577
28 Literature in Mansoura Ophthalmic Center ,Mansoura University Completed NCT03288116
29 Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application Completed NCT04018911 Hearing Aid with NR_4
30 Cost-efficacy of a Preliminary Diagnostic Program Using Bi-parametric Magnetic Resonance Imaging in Men With Suspicion of Prostate Cancer and no Previous Prostate Biopsy: a Prospective Randomized Clinical Study Comparing Multiparametric and Bi-parametric Magnetic Resonance Imaging Results Completed NCT03693703
31 Sleep Inertia and Functional Connectivity Between Brain Regions at Awakening : a Functional Magnetic Resonance Imaging (fMRI) Study Completed NCT03058159
32 Anatomical and Structural Connectivity in Schizophrenias Completed NCT02868879
33 Presence and Impact of CD73+ Th1.17 and of the CD39/CD73/Adenosine Cascade in Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PsA) Completed NCT03953378
34 A Pilot Study to Evaluate Molecular Imaging Methods in Primary Sjögren's Syndrome Completed NCT02899377
35 Developing Brain Stimulation as a Treatment for Pain in Opiate Dependent Individuals: Parametric Assessment of 2 Evidence-based Strategies Completed NCT03576781 Early Phase 1
36 Multi-parametric Magnetic Resonans Imaging in the Diagnosis and Surveillance of Low-risk Prostate Cancer Completed NCT02326246
37 Non-invasive Evaluation of Cardiopulmonary Diseases Using Transthoracic Parametric Doppler Based Assessment of Lung Doppler Signals Completed NCT02248831
38 Multi-Parametric Assessment of Breast Lymphedema Completed NCT02724514
39 Accuracy of Multi-parametric Prostate MRI and MRI-targeted, Ultrasound-navigated Prostate Fusion Biopsy in the Detection of Prostate Cancer: Completed NCT03615131
40 Development of Parametric Musculoskeletal Models to Investigate the Anatomy and the Function of the PIP Completed NCT03094962
41 Detection and Characterization of Cardio-Pulmonary Patho-Physiological States and Diseases by Transthoracic Parametric Doppler (TPD) Completed NCT01361139
42 An Exploratory Study to Investigate the Reparative and Regenerative Potential of Alemtuzumab in Relapsing-Remitting Multiple Sclerosis: A Multi-Parametric Non-Conventional MRI Sub-Study in Patient Participating in the CARE MS I and CARE MS II Studies Completed NCT01020370
43 Characterization of the Liver Parenchyma Using Parametric T1 and T2 Magnetic Resonance Relaxometry Completed NCT04623528
44 Relevance and Possible Nuisances of Respiratory Rate Alarm Generated by Multi-parametric Monitors in Non Ventilated ICU Patients.A Prospective, Monocentric, Observational Study Completed NCT02908659
46 Comparative Analysis of Software-based MRI-Ultrasound Image Fusion Against Cognitive Targeting of Multi-Parametric MRI Findings With Prostate Biopsy Completed NCT01964638
47 Multi-parametric Imaging of the Knee in Obese Patients With Knee Osteoarthritis Following a Significant Weight Loss, Investigating the Impact on Inflammation (A Substudy to "Effect of Liraglutide on Body Weight and Pain in Overweight or Obese Patients With Knee Osteoarthritis: A Randomised, Double Blind, Placebo-controlled, Parallel Group, Single-centre Trial" (NCT02905864) Completed NCT02928471
48 Personalised Postoperative Radiochemotherapy in Patients With Head and Neck Cancer and Development of a Multi-parametric Decision Support System for Personalised Medicine in Radiation Oncology Completed NCT02666885
49 Longitudinal Characterisation of the Host Microbiota After Kidney Donation and Transplantation Recruiting NCT04388930
50 RESting-state Functional MRI in Patients With Optic Neuritis for ANticipation of reCovEry Recruiting NCT04448938

Search NIH Clinical Center for Parametritis

Cochrane evidence based reviews: parametritis

Genetic Tests for Parametritis

Anatomical Context for Parametritis

MalaCards organs/tissues related to Parametritis:

Prostate, Liver, Uterus, Lung, Breast, Cervix

Publications for Parametritis

Articles related to Parametritis:

(show top 50) (show all 192)
# Title Authors PMID Year
Mapping the relationships between inflammatory bowel disease and comorbid diagnoses to identify disease associations. 61
32804850 2020
Devastating Gynecological Infections in Women with STAT3 Deficiency. 61
31916572 2020
[Pelvic cellulitis on pyogenic streptococcal bartholinitis: Case report]. 61
32112861 2020
Pelvic cellulitis caused by Raoultella planticola in a neutropenic patient. 61
30482700 2019
[Necrotizing fasciitis caused by a Garengeot's hernia. Case report]. 61
30148930 2018
An incidental finding of chronic salpingitis complications: Tubo-uterine fistula. 61
28976128 2017
Antibiotics for treating septic abortion. 61
27364644 2016
Uterine prolapse with endometrial eversion in association with an unusual diffuse, polypoid, fibrosing perimetritis and parametritis in a cat. 61
28491407 2016
Pelvic surgical site infections in gynecologic surgery. 61
25788822 2015
Changing perspectives of infectious causes of maternal mortality. 61
26692770 2015
[Importance of outpatient ultrasonografically guided transvaginal hydrolaparoscopy in the decision algorithm of care for the infertile couple.The results of the Centre for Assisted Reproduction Gennet Liberec 2012--2013]. 61
25054960 2014
Factors influencing the occurrence of pelvic cellulitis in women undergoing laparoscopic-assisted vaginal hysterectomy. 61
23548245 2013
Postoperative infections in obstetrics and gynecology. 61
23090459 2012
Factors influencing the occurrence of pelvic cellulitis in women undergoing laparoscopic-assisted vaginal hysterectomy. 61
23040949 2012
An analysis of risk factors for postoperative pelvic cellulitis after laparoscopic-assisted vaginal hysterectomy. 61
22212318 2011
[Outpatient treatments of haemorrhoidal disease]. 61
21831572 2011
Quality-initiated prophylactic antibiotic use in laparoscopic-assisted vaginal hysterectomy. 61
19133050 2008
Safety of Trans Vaginal Mesh procedure: retrospective study of 684 patients. 61
18937698 2008
The challenge of pelvic inflammatory disease. 61
16529095 2006
[Risk factors for prosthesis exposure in treatment of genital prolapse via the vaginal approach]. 61
16324871 2005
[Prosthetic reinforcement by the vaginal approach after surgical repair of pelvic prolapse]. 61
16319766 2005
Laparoscopic hysterectomy: the Kaiser Permanente San Diego experience. 61
15904592 2005
Antisepsis for abdominal hysterectomy: a randomised controlled trial of povidone-iodine gel. 61
15198760 2004
Pelvic inflammatory disease in adolescents. 61
15449845 2004
[Importance of microbiologic examination of vaginal secretions in the reproductive period]. 61
15227966 2004
Feasibility and safety of total laparoscopic radical hysterectomy. 61
14567809 2003
Tubo-ovarian abscess occurring 16 years after supracervical hysterectomy. 61
15022878 2003
[Investigation on administration method of carbapenems]. 61
12621741 2002
Management of lymphocysts after cervical carcinoma surgery. 61
11198039 2000
[Clinical trial with Veral in women with parametritis]. 61
11188009 2000
Abattoir survey of acquired reproductive abnormalities in ewes. 61
10358887 1999
[Puerperal endometritis and parametritis]. 61
10337776 1999
Colpopexy: a modification of Shaw's technique. 61
15512111 1998
Assessment of office-based care of sexually transmitted diseases and vaginitis and antibiotic decision-making by obstetrician-gynecologists. 61
9972486 1998
Sustained complete remission after incomplete chemoradiation complicated with pelvic cellulitis in a patient with recurrent cervical carcinoma. 61
9397613 1997
[The urological complications of contraception using intrauterine coils]. 61
9412010 1997
[Puerperal infection. Analysis of 618 cases]. 61
9102369 1997
Double-blind, multicenter, prospective randomized study of trospectomycin vs. Clindamycin, both with aztreonam, in non-community acquired obstetric and gynecologic infections. 61
18476152 1997
[Basic and clinical studies on biapenem (L-627) in obstetrics and gynecology]. 61
7877248 1994
Radical hysterectomy for recurrent carcinoma of the uterine cervix after radiotherapy. 61
7959262 1994
Pelvic inflammatory disease: diagnosis and management. 61
8184701 1994
To drain or not to drain: a retrospective study of closed-suction drainage following radical hysterectomy with pelvic lymphadenectomy. 61
8244174 1993
Piperacillin versus cefotetan as single-dose prophylaxis in abdominal hysterectomy: a prospective, randomized, multicenter study. 61
8515293 1993
The role of antibiotic prophylaxis for tubal microsurgery. 61
8161253 1993
[25 patients undergoing laparoscopy for pelvic pain]. 61
8441881 1993
Success with sacrospinous suspension of the prolapsed vaginal vault. 61
1440169 1992
Evaluation of new anti-infective drugs for the treatment of acute pelvic infections in hospitalized women. Infectious Diseases Society of America and the Food and Drug Administration. 61
1477250 1992
[Pyomyositis caused by Staphylococcus aureus]. 61
1507908 1992
Efficacy and tolerability of imipenem-cilastatin versus clindamycin+gentamicin for serious pelvic infections. 61
1576631 1992
Bacterial vaginitis. 61
1934710 1991

Variations for Parametritis

Expression for Parametritis

Search GEO for disease gene expression data for Parametritis.

Pathways for Parametritis

GO Terms for Parametritis

Cellular components related to Parametritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 10.02 TXNDC17 MPO MB ICAM1 F2 APOB
2 extracellular region GO:0005576 9.77 PTH PPBP OXT MPO MMP11 IL5
3 collagen-containing extracellular matrix GO:0062023 9.72 ICAM1 F3 F2 APOA1 APCS
4 blood microparticle GO:0072562 9.46 F2 APOA1 APCS ALB
5 extracellular space GO:0005615 9.44 PTH PPBP OXT MPO IL5 ICAM1
6 intermediate-density lipoprotein particle GO:0034363 9.26 APOB APOA1

Biological processes related to Parametritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular oxidant detoxification GO:0098869 9.61 TXNDC17 MPO ALB
2 cytokine-mediated signaling pathway GO:0019221 9.55 STAT3 PTPRN IL5 ICAM1 F3
3 chylomicron assembly GO:0034378 9.4 APOB APOA1
4 chylomicron remodeling GO:0034371 9.37 APOB APOA1
5 cellular protein metabolic process GO:0044267 9.35 F2 APOB APOA1 APCS ALB
6 lipoprotein biosynthetic process GO:0042158 9.32 APOB APOA1
7 negative regulation by host of viral process GO:0044793 9.26 CRP APCS
8 acute-phase response GO:0006953 8.92 STAT3 F2 CRP APCS

Molecular functions related to Parametritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 virion binding GO:0046790 8.96 CRP APCS
2 complement component C1q binding GO:0001849 8.62 CRP APCS

Sources for Parametritis

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
69 Tocris
71 UMLS via Orphanet
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