MCID: PRP015
MIFTS: 32

Paraphilia Disorder

Categories: Mental diseases

Aliases & Classifications for Paraphilia Disorder

MalaCards integrated aliases for Paraphilia Disorder:

Name: Paraphilia Disorder 12 15
Paraphilias 73
Paraphilia 76

Classifications:



External Ids:

Disease Ontology 12 DOID:0060044
UMLS 73 C0030482

Summaries for Paraphilia Disorder

MalaCards based summary : Paraphilia Disorder, also known as paraphilias, is related to social phobia and voyeurism. An important gene associated with Paraphilia Disorder is PNP (Purine Nucleoside Phosphorylase), and among its related pathways/superpathways are Osteoclast Signaling and Glycine, serine and threonine metabolism. Affiliated tissues include brain and bone, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 76 Paraphilia (previously known as sexual perversion and sexual deviation) is the experience of intense... more...

Related Diseases for Paraphilia Disorder

Diseases related to Paraphilia Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 social phobia 30.3 MAOA PRL
2 voyeurism 29.8 CBS SLC4A4 SLC4A8
3 obsessive-compulsive disorder 29.6 MAOA OXT PRL
4 disease of mental health 29.4 GRN MAOA OXT RTN4
5 fetishism 29.2 CBS KHDRBS3 OXT RFX6 SLC4A4 SLC4A8
6 transvestism 28.9 CBS KHDRBS3 OXT RFX6 SLC4A4 SLC4A8
7 pedophilia 28.8 GOLGB1 GRN IFNB1 IRGC LPP OXT
8 exhibitionism 28.8 ABCB6 ADD2 CBS MAOA MAOB PNP
9 bestiality 11.4
10 atypical depressive disorder 10.2 MAOA MAOB
11 ideomotor apraxia 10.2 CBS GRN
12 stereotypic movement disorder 10.2 ABCB6 PRL
13 kleptomania 10.2 ABCB6 MAOA
14 gait apraxia 10.2 CBS GRN
15 trichotillomania 10.2 ABCB6 PRL
16 sexual sadism 10.1
17 dependent personality disorder 10.1 MAOA MAOB TNFSF11
18 pathological gambling 10.1 MAOA MAOB
19 dementia, lewy body 10.1 CBS GRN MAOB
20 attention deficit-hyperactivity disorder 10.0
21 androgenic alopecia 10.0 LPP PRL
22 serotonin syndrome 9.9 MAOA MAOB OXT
23 postpartum depression 9.9 MAOA OXT PRL
24 echolalia 9.9 ADD2 CBS GRN IRGC
25 osteoporosis 9.9
26 parkinson disease, late-onset 9.9
27 schizophrenia 9.9
28 transsexuality 9.9
29 anorexia nervosa 9.9
30 sexual disorder 9.9
31 obsessive-compulsive personality disorder 9.9
32 impulse control disorder 9.9
33 intermittent explosive disorder 9.9
34 hypoactive sexual desire disorder 9.9
35 avoidant personality disorder 9.9
36 personality disorder 9.9
37 dwarfism 9.9
38 depression 9.9
39 breast abscess 9.9 IFNB1 OXT
40 multiple personality disorder 9.8 IRGC OXT TNFSF11
41 hemometra 9.8 OXT PNP
42 specific developmental disorder 9.8 GRN OXT RTN4
43 separation anxiety disorder 9.8 OXT PRL RTN4

Graphical network of the top 20 diseases related to Paraphilia Disorder:



Diseases related to Paraphilia Disorder

Symptoms & Phenotypes for Paraphilia Disorder

GenomeRNAi Phenotypes related to Paraphilia Disorder according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00106-A-0 10.02 MAOA
2 Decreased viability GR00381-A-1 10.02 PNP RTN4
3 Decreased viability GR00402-S-2 10.02 ABCB6 ADD2 CBS GOLGB1 GRN IFNB1
4 no effect GR00402-S-1 9.62 ABCB6 ADD2 CBS GOLGB1 GRN IFNB1

MGI Mouse Phenotypes related to Paraphilia Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.65 ADD2 GOLGB1 GRN KHDRBS3 MAOA MAOB
2 homeostasis/metabolism MP:0005376 9.47 ABCB6 ADD2 GRN IFNB1 LPP MAOA

Drugs & Therapeutics for Paraphilia Disorder

Search Clinical Trials , NIH Clinical Center for Paraphilia Disorder

Genetic Tests for Paraphilia Disorder

Anatomical Context for Paraphilia Disorder

MalaCards organs/tissues related to Paraphilia Disorder:

41
Brain, Bone

Publications for Paraphilia Disorder

Articles related to Paraphilia Disorder:

(show top 50) (show all 105)
# Title Authors Year
1
Sex on the Silver Screen: Using Film to Teach About Paraphilias. ( 28685351 )
2018
2
Paraphilias and the ICD-11: Progress but Still Logically Inconsistent. ( 29294228 )
2018
3
Diagnostic Issues in the Paraphilias. ( 30032364 )
2018
4
Fanon and the New Paraphilias: Towards a Trans of Color Critique of the DSM-V. ( 30076507 )
2018
5
Paraphilias in the DSM-5. ( 26772210 )
2016
6
Single-victim and serial sexual homicide offenders: differences in crime, paraphilias and personality traits. ( 25111158 )
2015
7
Paraphilias and paraphilic disorders in Parkinson's disease: A systematic review of the literature. ( 25759330 )
2015
8
Psychological Treatment of the Paraphilias: a Review and an Appraisal of Effectiveness. ( 25903481 )
2015
9
Between DSM and ICD: Paraphilias and the Transformation of Sexual Norms. ( 25933671 )
2015
10
Paraphilias. ( 26382165 )
2015
11
Kinky parents and child custody: the effect of the DSM-5 differentiation between the paraphilias and paraphilic disorders. ( 24473942 )
2014
12
Assessment of the paraphilias. ( 24877702 )
2014
13
Pharmacologic treatment of paraphilias. ( 24877704 )
2014
14
The natural history of the paraphilias. ( 24877711 )
2014
15
Controversies in the diagnosis and treatment of paraphilias. ( 23152966 )
2013
16
Problems with paraphilias in the DSM-5. ( 23881707 )
2013
17
Paraphilias: definition, diagnosis and treatment. ( 24049640 )
2013
18
Philosophical issues in the paraphilias. ( 24060913 )
2013
19
Pragmatic and Darwinian views of the paraphilias. ( 22124749 )
2012
20
Dopaminergic-induced paraphilias associated with impulse control and related disorders in patients with Parkinson disease. ( 23096066 )
2012
21
Cognitive-behavioral treatment of the paraphilias. ( 23585466 )
2012
22
Pharmacological treatment of paraphilias. ( 23585467 )
2012
23
The use of online methodologies in studying paraphilias - A review. ( 26165601 )
2012
24
How unusual are the contents of paraphilias? Paraphilia-associated sexual arousal patterns in a community-based sample of men. ( 19929918 )
2011
25
Why are the paraphilias mental disorders? ( 21044271 )
2011
26
Proposals to add new paraphilias to the Diagnostic and Statistical Manual, Edition 5 (DSM-5). ( 21389175 )
2011
27
A brief history of field trials of the DSM diagnostic criteria for paraphilias. ( 21491137 )
2011
28
Current concepts in the pharmacotherapy of paraphilias. ( 21504253 )
2011
29
DSM-5 proposed diagnostic criteria for sexual paraphilias: tensions between diagnostic validity and forensic utility. ( 21531463 )
2011
30
Sampling Extreme Groups Invalidates Research on the Paraphilias: Implications for DSM-5 and Sex Offender Risk Assessments. ( 21796673 )
2011
31
Emotion and Morality in Psychopathy and Paraphilias. ( 24899928 )
2011
32
Disinhibition and narrative in the paraphilias. ( 20067815 )
2010
33
Paraphilias and sexual offences in the Bible. ( 20129434 )
2010
34
Paraphilias across cultures: contexts and controversies. ( 20358463 )
2010
35
Paraphilias in schizophrenia: differential diagnosis and treatment with selective serotonin reuptake inhibitors. ( 20403404 )
2010
36
Paraphilias with co-morbid psychopathy: the clinical and legal significance to sex offender assessments. ( 20422646 )
2010
37
Paraphilias in adult psychiatric inpatients. ( 20445840 )
2010
38
WFSBP treatment guidelines for the biological treatment of paraphilias. ( 20459369 )
2010
39
The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of paraphilias. ( 20459370 )
2010
40
DSM-5 proposals for paraphilias: suggestions for reducing false positives related to use of behavioral manifestations. ( 20697936 )
2010
41
References to the paraphilias and sexual crimes in the Bible. ( 19239958 )
2009
42
The treatment of paraphilias: an historical perspective. ( 18383202 )
2008
43
Issues for DSM-V: unintended consequences of small changes: the case of paraphilias. ( 18829878 )
2008
44
Evidence of primary, secondary, and collateral paraphilias left at serial murder and sex offender crime scenes. ( 17681002 )
2007
45
Mania associated with multiple paraphilias. ( 16444087 )
2006
46
The influence of brain abnormalities on psychosocial development, criminal history and paraphilias in sexual murderers. ( 16225232 )
2005
47
Osteoporosis associated with the treatment of paraphilias: a clinical review of seven case reports. ( 12877306 )
2003
48
Pharmacotherapy of paraphilias with long-acting agonists of luteinizing hormone-releasing hormone: a systematic review. ( 12927003 )
2003
49
Differential pharmacological treatment of paraphilias and sex offenders. ( 12971182 )
2003
50
Hypersexual desire in males: are males with paraphilias different from males with paraphilia-related disorders? ( 14571536 )
2003

Variations for Paraphilia Disorder

Expression for Paraphilia Disorder

Search GEO for disease gene expression data for Paraphilia Disorder.

Pathways for Paraphilia Disorder

GO Terms for Paraphilia Disorder

Cellular components related to Paraphilia Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial envelope GO:0005740 8.62 ABCB6 MAOB

Biological processes related to Paraphilia Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.35 GRN IFNB1 OXT PRL TNFSF11
2 regulation of intracellular pH GO:0051453 9.32 SLC4A4 SLC4A8
3 anion transport GO:0006820 9.26 SLC4A4 SLC4A8
4 neurotransmitter catabolic process GO:0042135 9.16 MAOA MAOB
5 dopamine catabolic process GO:0042420 8.62 MAOA MAOB

Molecular functions related to Paraphilia Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anion transmembrane transporter activity GO:0008509 9.26 SLC4A4 SLC4A8
2 inorganic anion exchanger activity GO:0005452 9.16 SLC4A4 SLC4A8
3 primary amine oxidase activity GO:0008131 8.96 MAOA MAOB
4 sodium:bicarbonate symporter activity GO:0008510 8.62 SLC4A4 SLC4A8

Sources for Paraphilia Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....