MCID: PRQ001
MIFTS: 15

Paraquat Lung

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Paraquat Lung

MalaCards integrated aliases for Paraquat Lung:

Name: Paraquat Lung 53 73
Paraquat Induced Lung Disease 53

Classifications:



External Ids:

UMLS 73 C2931434

Summaries for Paraquat Lung

MalaCards based summary : Paraquat Lung, also known as paraquat induced lung disease, is related to toxic pneumonitis and meconium aspiration syndrome. An important gene associated with Paraquat Lung is SCGB1A1 (Secretoglobin Family 1A Member 1). Affiliated tissues include lung, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Paraquat Lung

Diseases related to Paraquat Lung via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 toxic pneumonitis 9.6 SCGB1A1 SFTPB
2 meconium aspiration syndrome 9.6 SCGB1A1 SFTPB
3 bronchopulmonary dysplasia 9.5 SCGB1A1 SFTPB
4 respiratory failure 9.5 SCGB1A1 SFTPB
5 pneumonia 9.4 SCGB1A1 SFTPB
6 pulmonary disease, chronic obstructive 9.3 SCGB1A1 SFTPB
7 pulmonary fibrosis, idiopathic 9.2 SCGB1A1 SFTPB
8 lung cancer susceptibility 3 9.0 SCGB1A1 SFTPB

Graphical network of the top 20 diseases related to Paraquat Lung:



Diseases related to Paraquat Lung

Symptoms & Phenotypes for Paraquat Lung

GenomeRNAi Phenotypes related to Paraquat Lung according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.36 SCGB1A1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-129 9.36 SCGB1A1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-140 9.36 SFTPB
4 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.36 SFTPB
5 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.36 SCGB1A1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-162 9.36 SCGB1A1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.36 SFTPB
8 Increased shRNA abundance (Z-score > 2) GR00366-A-41 9.36 SCGB1A1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.36 SCGB1A1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.36 SCGB1A1 SFTPB

Drugs & Therapeutics for Paraquat Lung

Search Clinical Trials , NIH Clinical Center for Paraquat Lung

Genetic Tests for Paraquat Lung

Anatomical Context for Paraquat Lung

MalaCards organs/tissues related to Paraquat Lung:

41
Lung

Publications for Paraquat Lung

Articles related to Paraquat Lung:

(show all 15)
# Title Authors Year
1
Pneumoproteins as markers of paraquat lung injury: a clinical case. ( 17174135 )
2008
2
Remodeling of the alveolar structure in the paraquat lung of humans: a morphometric study. ( 8026829 )
1994
3
Betamethasone effects on paraquat lung toxicity. ( 1663675 )
1991
4
An immunohistochemical study of the fibrosing process in paraquat lung injury. ( 2505447 )
1989
5
Effectiveness of vitamin E and colchicine in amelioration of paraquat lung injuries using an experimental model. ( 2703331 )
1989
6
Changes in elastic-related fibers in the human paraquat lung. ( 3172552 )
1988
7
The effect of paraquat lung on mononuclear cells. ( 2461865 )
1988
8
Paraquat lung: is there a role for radiotherapy? ( 3817832 )
1987
9
A cautionary note on the resolution of paraquat lung damage after radiotherapy. ( 3842623 )
1985
10
Radiotherapy for paraquat lung toxicity. ( 6428680 )
1984
11
PEEP-induced airspace overdistension complicating paraquat lung. ( 7042228 )
1982
12
Paraquat lung injury in rabbits. ( 698141 )
1978
13
Paraquat lung: a reappraisal. ( 4480097 )
1974
14
The ultrastructure and time sequence of the early stages of paraquat lung in rats. ( 4141727 )
1974
15
The ultrastructure of the paraquat lung lesion in the rat. ( 4746189 )
1973

Variations for Paraquat Lung

Expression for Paraquat Lung

Search GEO for disease gene expression data for Paraquat Lung.

Pathways for Paraquat Lung

GO Terms for Paraquat Lung

Sources for Paraquat Lung

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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