MCID: PRQ001
MIFTS: 16

Paraquat Lung

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Paraquat Lung

MalaCards integrated aliases for Paraquat Lung:

Name: Paraquat Lung 20 70
Paraquat Induced Lung Disease 20

Classifications:



External Ids:

UMLS 70 C2931434

Summaries for Paraquat Lung

MalaCards based summary : Paraquat Lung, also known as paraquat induced lung disease, is related to respiratory failure and bacterial pneumonia. An important gene associated with Paraquat Lung is SCGB1A1 (Secretoglobin Family 1A Member 1). Affiliated tissues include lung, bone marrow and brain, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Paraquat Lung

Graphical network of the top 20 diseases related to Paraquat Lung:



Diseases related to Paraquat Lung

Symptoms & Phenotypes for Paraquat Lung

GenomeRNAi Phenotypes related to Paraquat Lung according to GeneCards Suite gene sharing:

26 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-119 9.47 SCGB1A1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.47 SCGB1A1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-139 9.47 SCGB1A1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.47 SFTPB
5 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.47 SCGB1A1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-20 9.47 SFTPB
7 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.47 SFTPB
8 Increased shRNA abundance (Z-score > 2) GR00366-A-41 9.47 SCGB1A1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-55 9.47 SFTPB
10 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.47 SCGB1A1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-65 9.47 SFTPB
12 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.47 SFTPB
13 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.47 SCGB1A1 SFTPB

Drugs & Therapeutics for Paraquat Lung

Search Clinical Trials , NIH Clinical Center for Paraquat Lung

Genetic Tests for Paraquat Lung

Anatomical Context for Paraquat Lung

MalaCards organs/tissues related to Paraquat Lung:

40
Lung, Bone Marrow, Brain

Publications for Paraquat Lung

Articles related to Paraquat Lung:

(show all 45)
# Title Authors PMID Year
1
[CT manifestations and prognosis of acute paraquat induced lung injury]. 61
32306680 2020
2
Radiomics Nomogram Analyses for Differentiating Pneumonia and Acute Paraquat Lung Injury. 61
31636276 2019
3
[Lung transplantation in patients with paraquat poisoning: a case report and literature review]. 61
31177699 2019
4
[The protective effect of bone marrow mesenchymal stem cells carrying antioxidant gene superoxide dismutase on paraquat lung injury in mice]. 61
27014807 2016
5
[The prevention and therapeutics effect of sodium bicarbonate with gastric lavage, atomization inhalation and intravenous injection on the patients with paraquat poisoning and pulmonary fibrosis induced by paraquat poisoning]. 61
26832708 2015
6
The preventive effect of atorvastatin on paraquat-induced pulmonary fibrosis in the rats. 61
25436189 2014
7
[Paraquat lung and monoamine transporter]. 61
21114046 2010
8
Pneumoproteins as markers of paraquat lung injury: a clinical case. 61
17174135 2008
9
G-protein activation and expression in lung injury. 61
9591329 1998
10
[Distribution of ventilation-perfusion ratios in paraquat-induced interstitial pneumonia in dogs]. 61
8641680 1996
11
Pulmonary damage due to paraquat poisoning through skin absorption. 61
7784705 1995
12
[Respiratory disease in the tertiary emergency hospital]. 61
7602842 1994
13
Remodeling of the alveolar structure in the paraquat lung of humans: a morphometric study. 61
8026829 1994
14
[Paraquat lung]. 61
8152058 1994
15
Dynamic changes in the functional characteristics of the interstitial fibroblast during lung repair. 61
1516567 1992
16
Betamethasone effects on paraquat lung toxicity. 61
1663675 1991
17
[Observations of the fibrosing process in paraquat lung injury by chest X-ray and CT]. 61
1886307 1991
18
Paraquat pharmacokinetics using a subcutaneous toxic low dose in the rat. 61
2307319 1990
19
[Fibrogenesis and glycoconjugates]. 61
2796048 1989
20
Effectiveness of vitamin E and colchicine in amelioration of paraquat lung injuries using an experimental model. 61
2703331 1989
21
An immunohistochemical study of the fibrosing process in paraquat lung injury. 61
2505447 1989
22
Changes in elastic-related fibers in the human paraquat lung. 61
3172552 1988
23
Pulmonary elastic fiber degradation in paraquat toxicity. An electron microscopic immunohistochemical study. 61
3370614 1988
24
The effect of paraquat lung on mononuclear cells. 61
2461865 1988
25
Brain damage due to paraquat poisoning: a fatal case with neuropathological examination of the brain. 61
3205434 1988
26
Paraquat lung: is there a role for radiotherapy? 61
3817832 1987
27
[Ultrastructural changes on the alveolar surface in experimental respiratory distress syndrome with emphasis on the detection of surfactants]. 61
3639770 1986
28
[Observations on paraquat lung during the recovery course by X-ray CT (three-window method)]. 61
3773291 1986
29
[Pneumonitis with fatal pulmonary fibrosis (Hamman-Rich syndrome) due to parathion-(E-605-) poisoning]. 61
3012677 1986
30
Similarity of isozyme pattern of serum lactate dehydrogenase following treatments with O,O,S-trimethyl phosphorothioate and paraquat. 61
3715918 1986
31
A cautionary note on the resolution of paraquat lung damage after radiotherapy. 61
3842623 1985
32
[A study of paraquat lung]. 61
4068299 1985
33
Radiotherapy for paraquat lung toxicity. 61
6428680 1984
34
Collagen stimulating factors from lung in experimental paraquat poisoning demonstrated in vitro and in vivo. 61
6327775 1984
35
PEEP-induced airspace overdistension complicating paraquat lung. 61
7042228 1982
36
Depression of serotonin uptake by rat lungs exposed to paraquat. 61
7062288 1982
37
Effect of paraquat on serum angiotensin converting enzyme. 61
6250433 1980
38
Paraquat lung injury in rabbits. 61
698141 1978
39
Pulmonary histological appearances in fatal paraquat poisoning. 61
669589 1978
40
[Paraquat lung (author's transl)]. 61
560042 1977
41
Changes in integrated vagal afferent activity induced by model lung diseases in rats. 61
141674 1977
42
The ultrastructure and time sequence of the early stages of paraquat lung in rats. 61
4141727 1974
43
Paraquat lung: a reappraisal. 61
4480097 1974
44
[Pathogenesis of paraquat-lung (author's transl)]. 61
4420858 1974
45
The ultrastructure of the paraquat lung lesion in the rat. 61
4746189 1973

Variations for Paraquat Lung

Expression for Paraquat Lung

Search GEO for disease gene expression data for Paraquat Lung.

Pathways for Paraquat Lung

GO Terms for Paraquat Lung

Sources for Paraquat Lung

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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