Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: PRS033
MIFTS: 28

Parasitic Ectoparasitic Infectious Disease

Categories: Infectious diseases
Genes Tissues Related diseases Publications Drugs
Sources

Aliases & Classifications for Parasitic Ectoparasitic Infectious Disease

About this section

MalaCards integrated aliases for Parasitic Ectoparasitic Infectious Disease:

Name: Parasitic Ectoparasitic Infectious Disease 12 15
Ectoparasitic Infestations 45 74
Ectoparasitism 12

Classifications:

MalaCards categories:
Global: Infectious diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:4110
MeSH 45 D004478
UMLS 74 C0013578
Sources

Summaries for Parasitic Ectoparasitic Infectious Disease

About this section
Disease Ontology : 12 A parasitic infectious disease that is caused by organisms that live primarily on the surface of the host.

MalaCards based summary : Parasitic Ectoparasitic Infectious Disease, also known as ectoparasitic infestations, is related to myiasis and tick infestation. An important gene associated with Parasitic Ectoparasitic Infectious Disease is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I). The drugs Permethrin and Ivermectin have been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotype is Lamellipodia cells.

Wikipedia : 77 An ectoparasitic infestation is a parasitic disease caused by organisms that live primarily on the... more...

Sources

Related Diseases for Parasitic Ectoparasitic Infectious Disease

About this section

Diseases related to Parasitic Ectoparasitic Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 myiasis 32.4 FARSA MT-CO1
2 tick infestation 32.0 ABCB8 MAP1B STAB2
3 mite infestation 32.0 AADACL3 DSCAML1
4 lice infestation 32.0 MT-CO1 PYURF TMEM132D
5 scabies 11.4
6 tungiasis 11.3
7 leech infestation 11.3
8 epidemic typhus 10.4
9 plague 10.4
10 endemic typhus 10.3
11 pediculus humanus capitis infestation 10.2 FARSA MT-CO1
12 dirofilariasis 10.2 MT-CO1 STAB2
13 papillomatosis, confluent and reticulated 10.2
14 cystic fibrosis 10.2
15 pthirus pubis infestation 10.2 MT-CO1 TMEM132D
16 bornholm eye disease 10.1
17 skin disease 10.1
18 louping ill 10.1
19 hymenolepiasis 10.0 MT-CO1 TRIM33
20 sarcocystosis 10.0 FARSA PYURF
21 parasitic protozoa infectious disease 10.0 FARSA MT-CO1
22 buschke-ollendorff syndrome 9.9
23 cutaneous leishmaniasis 9.9
24 systemic scleroderma 9.9
25 tick-borne encephalitis 9.9
26 cysticercosis 9.9
27 bartonellosis 9.9
28 rabies 9.9
29 tick paralysis 9.9
30 kyasanur forest disease 9.9
31 allergic hypersensitivity disease 9.9
32 chagas disease 9.9
33 patulous eustachian tube 9.9
34 scrub typhus 9.9
35 chronic wasting disease 9.9
36 lymphopenia 9.9
37 prion disease 9.9
38 leishmaniasis 9.9
39 encephalitis 9.9
40 yellow fever 9.9
41 hypereosinophilic syndrome 9.9
42 wells syndrome 9.9
43 hendra virus infection 9.9
44 norwegian scabies 9.8 AADACL3 MT-CO1 TRIM33

Graphical network of the top 20 diseases related to Parasitic Ectoparasitic Infectious Disease:



Diseases related to Parasitic Ectoparasitic Infectious Disease
Sources

Symptoms & Phenotypes for Parasitic Ectoparasitic Infectious Disease

About this section

GenomeRNAi Phenotypes related to Parasitic Ectoparasitic Infectious Disease according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Lamellipodia cells GR00165-A 8.92 ABCB8 DSCAML1 TMEM132D TRIM33
Sources

Drugs & Therapeutics for Parasitic Ectoparasitic Infectious Disease

About this section

Drugs for Parasitic Ectoparasitic Infectious Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 42)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Permethrin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 52645-53-1 40326
2
Ivermectin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 70288-86-7 6474909
3
Azithromycin Approved Phase 4,Phase 3,Not Applicable 83905-01-5 447043 55185
4 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Not Applicable
5 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
6 Pharmaceutical Solutions Phase 4,Phase 2,Not Applicable
7
Malathion Approved, Investigational Phase 3,Phase 2,Phase 1 121-75-5 4004
8
Albendazole Approved, Vet_approved Phase 3,Not Applicable 54965-21-8 2082
9
Diethylcarbamazine Approved, Investigational, Vet_approved Phase 3,Not Applicable 90-89-1 3052
10 Rue Phase 3
11 Emollients Phase 3
12 Dermatologic Agents Phase 3
13 Cholinesterase Inhibitors Phase 3,Phase 2,Phase 1
14 Neurotransmitter Agents Phase 3,Phase 2,Phase 1
15 Cholinergic Agents Phase 3,Phase 2,Phase 1
16 Antimitotic Agents Phase 3,Not Applicable
17 Anti-Bacterial Agents Phase 3,Phase 1
18 Lipoxygenase Inhibitors Phase 3,Not Applicable
19 Anthelmintics Phase 3,Phase 2,Not Applicable
20 Antiprotozoal Agents Phase 3,Not Applicable
21 Pulmonary Surfactants Phase 3,Phase 2
22
Ethanol Approved Phase 2 64-17-5 702
23
Benzyl alcohol Approved Phase 2 100-51-6 244
24 Peripheral Nervous System Agents Phase 2
25 Anesthetics Phase 2
26 Anesthetics, Local Phase 2
27 Central Nervous System Depressants Phase 2
28 Neem Phase 2
29 Milbemycin Phase 2
30
Norgestimate Approved, Investigational Phase 1 35189-28-7 6540478
31
Ethinyl Estradiol Approved Phase 1 57-63-6 5991
32
Polyestradiol phosphate Approved Phase 1 28014-46-2
33
Estradiol Approved, Investigational, Vet_approved Phase 1 50-28-2 5757
34
Moxifloxacin Approved, Investigational Phase 1 354812-41-2, 151096-09-2 152946
35 Contraceptives, Oral, Combined Phase 1
36 Contraceptives, Oral Phase 1
37 Estradiol 3-benzoate Phase 1
38 Topoisomerase Inhibitors Phase 1
39 Contraceptive Agents Phase 1
40 Estradiol 17 beta-cypionate Phase 1
41 Norgestimate, ethinyl estradiol drug combination Phase 1
42 Liver Extracts Not Applicable

Interventional clinical trials:

(show top 50) (show all 59)
# Name Status NCT ID Phase Drugs
1 Pharmacokinetic (PK) and Tolerance Study of Natroba Topical Suspension in Pediatrics With an Active Head Lice Infestation Completed NCT01660321 Phase 4 spinosad
2 Trial of the Ovicidal Activity of Three Head Lice Products (NeutraLice Lotion®, NeutraLice Advance® and Moov Head Lice Solution®) After a Single Application Completed NCT00995124 Phase 4 NeutraLice Lotion;NeutraLice Advance Solution;Moov Head Lice Solution
3 Azithromycin - Ivermectin Mass Drug Administration for Skin Disease Completed NCT02775617 Phase 4 Ivermectin;Azithromycin;Permethrin
4 Efficacy and Safety Study for PIOLIN® Shampoo Unknown status NCT01966965 Phase 3 PIOLIN®;NEDAX
5 Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies Unknown status NCT02841215 Phase 3 Ivermectin 200 µg/kg;Ivermectin 400 µg/kg
6 Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children Unknown status NCT02407782 Phase 3 Ivermectin;Permethrin
7 P3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02062060 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
8 Phase 3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02060903 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
9 Ivermectin in the Treatment of Head Lice Completed NCT00819520 Phase 3 ivermectin;malathion
10 Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Completed NCT00545168 Phase 3 Spinosad;Spinosad;Permethrin 1%
11 Safety and Efficacy of a Novel Malathion Formulation in the Treatment of Head Lice Completed NCT00244439 Phase 3 MALG;Ovide (malathion) lotion 0.05%;Permethrin 1%
12 A Clinical Endpoint Bioequivalence Study to Assess Efficacy and Safety of Ivermectin 0.5% Lotion in the Treatment of Head Lice Completed NCT03337490 Phase 3 Ivermectin 0.5% Topical Application Lotion;Ivermectin 0.5% Topical Application Lotion [SKLICE];Placebo 0% Lotion
13 Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice Completed NCT00963508 Phase 3 Malathion gel 0.5%;Permethrin 1% rinse (Nix Crème)
14 Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice Completed NCT00927472 Phase 3 Malathion gel 0.5%;Permethrin 1% rinse
15 Safety and Tolerability of a Novel Malathion Formulation in Children Age 6-24 Months With Head Lice Completed NCT00752973 Phase 2, Phase 3 MALG (malathion) Treatment
16 Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Completed NCT00545753 Phase 3 Spinosad;Spinosad;Permethrin 1%
17 Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice Completed NCT00479310 Phase 3 Summers 5% L.A.
18 A Randomised, Assessor-Blind, Comparative Efficacy Clinical Trial of 3 Pediculicides. Completed NCT00381082 Phase 2, Phase 3 1) MOOV Head Lice Treatment (Ego Pharmaceutical).;Banlice Mousse Aerosol (Pfizer, Australia);3) KP24 Medicated Foam (Nelson Laboratories)
19 Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice Completed NCT00301340 Phase 3 5% Lice Asphyxiator lotion - Summers Laboratories, Inc.
20 Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice. Completed NCT00301327 Phase 3 Summers 5% L.A.
21 Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands Completed NCT03236168 Phase 3 Ivermectin;Permethrin 5%;Malathion Shampoo 0.5%
22 Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% in the Treatment of Scabies Completed NCT03178942 Phase 3 Permethrin Cream, 5%;Elimiteâ„¢ Cream (permethrin) 5%
23 Bio-equivalence Study Comparing Permethrin Cream, 5% With Elimite in Patients With Active Scabies. Completed NCT02978508 Phase 3 Permethrin Cream, 5%;Elimite
24 A Study to Evaluate the Therapeutic Equivalence of Generic Permethrin Cream 5% to Elimite® in the Treatment of Scabies Completed NCT02572986 Phase 3 Permethrin
25 Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies Completed NCT02485717 Phase 3 spinosad topical suspension, 0.9%
26 Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies Completed NCT02485704 Phase 3 spinosad topical suspension, 0.9%
27 Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs ) Completed NCT03676140 Phase 3 Albendazole on Day 1;Ivermectin on Day 1;Diethylcarbamazine on day 1;Azithromycin on Day 1;Azithromycin on Day 8
28 Cocamide DEA vs Permethrin for Head Lice Terminated NCT02500524 Phase 3 Cocamide diethanolamine;Permethrin
29 Two Treatment Regimens of Cocamide DEA Lotion for Head Lice Terminated NCT02499549 Phase 2, Phase 3 cocamide diethanolamine
30 Efficacy and Safety of Topical 0.5% Ivermectin Lotion for the Treatment of Head Lice Infestation in Filipinos Completed NCT03286101 Phase 2 0.5% Ivermectin lotion;Vehicle
31 Ovicidal Efficacy and Safety of Abametapir Lotion 0.74% Administered for the Treatment of Head Lice Infestation Completed NCT02097485 Phase 2 Abametapir Lotion 0.74% w/w;Vehicle Lotion
32 A Pediatric Safety and Pharmacokinetics Study of Ha44 Gel Administered Topically for Treatment of Head Lice Infestation Completed NCT02010333 Phase 2 Ha44 Gel 0.74% w/w
33 Safety and PK Study of Ha44 Gel Under Maximal Use Conditions for Treatment of Head Lice Infestation Completed NCT01907490 Phase 2 Ha44 Gel
34 An Efficacy and Safety Study of Ha44 Gel Administered Topically for the Treatment of Head Lice Infestation Completed NCT01336647 Phase 2 Group A - Low-Dose Ha44 0.37% w/w;Group B - High Dose Ha44 Gel 0.74% w/w;Group C - Placebo
35 Dose Ranging Study of Ivermectin Treatment Conditioner in Subjects With Head Lice Infestation Completed NCT00857948 Phase 2 ivermectin treatment conditioner;Placebo, vehicle control
36 A Study Evaluating the Safety and Efficacy of BGC20-0582 Lice Treatment Gel for Head Lice Infestation Completed NCT00528021 Phase 2 Placebo;BGC20-0582
37 Neem Lotion With Combing for Lice Completed NCT02974088 Phase 2
38 A Pilot Dose Ranging Study of Spinosad Creme Rinse Completed NCT00858481 Phase 2 Spinosad Creme Rinse - Vehicle Control;Spinosad Creme Rinse;Spinosad Creme Rinse;Spinosad Creme Rinse
39 A Safety and Efficacy Pilot Study Comparing NatrOVA Creme Rinse 1% and NIX Creme Rinse Completed NCT00857935 Phase 2 NatrOVA Creme Rinse - 1%;NIX Creme Rinse - 1% permethrin
40 A Dose Ranging Study of Different Strengths of Spinosad Topical Creme in Subjects With Pediculosis Capitis Completed NCT00311779 Phase 2 Spinosad Creme Rinse
41 A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies Completed NCT02094716 Phase 2 Permethrin Foam 4%;Permethrin Foam 5%;Vehicle Foam
42 Comparison of the Efficacy and Safety of Ivermectin to Permethrin Completed NCT00262418 Phase 2 Administration of ivermectin or permethrin
43 Dose-finding Study of Moxidectin for Treatment of Scabies Not yet recruiting NCT03905265 Phase 2 Moxidectin Oral Product
44 Safety and Tolerability of a Novel Malathion Formulation in Infants and Toddlers With Head Lice Terminated NCT00291057 Phase 2 MALG
45 Study to Evaluate the Effect of Ha44 Gel on the Electrocardiogram in Healthy Volunteers Completed NCT01518699 Phase 1 Ha44;Ha44 Placebo;Moxifloxacin Placebo;Moxifloxacin
46 Pharmacokinetics of Malathion Gel 0.5% and Malathion 0.5% Lotion (Ovide) in Patients With Head Lice Completed NCT00927407 Phase 1 Malathion gel 0.5%;Malathion lotion 0.5%
47 A Pharmacokinetic (PK) Study of NatrOVA Topical Creme (1%) in Pediatric Subjects 6 to 24 Months of Age Completed NCT00410709 Phase 1 NatrOVA Creme Rinse (1%)
48 A Clinical Trial to Evaluate Efficacy and Safety of a Water-soluble Head Lice Product. Completed NCT03617926 Not Applicable
49 Treatment of Pediculosis (Head Lice) in Senegal Completed NCT03578679 Not Applicable Ivermectin Oral Product
50 A Study to Evaluate the Safety and Efficacy of Product X92001327 vs RID Shampoo in Subjects With Head Lice Completed NCT01803581 Not Applicable

Search NIH Clinical Center for Parasitic Ectoparasitic Infectious Disease

Cochrane evidence based reviews: ectoparasitic infestations

Sources

Genetic Tests for Parasitic Ectoparasitic Infectious Disease

About this section
Sources

Anatomical Context for Parasitic Ectoparasitic Infectious Disease

About this section

MalaCards organs/tissues related to Parasitic Ectoparasitic Infectious Disease:

42
Skin, Eye
Sources

Publications for Parasitic Ectoparasitic Infectious Disease

About this section

Articles related to Parasitic Ectoparasitic Infectious Disease:

# Title Authors Year
1
The Role of Dermatoscopy in Infectious Diseases Affecting the Skin, Part 2: Mycologic Infections and Ectoparasitic Infestations. ( 30413225 )
2018
2
Ectoparasitic infestations of the European hedgehog (Erinaceus europaeus) in Urmia city, Iran: First report. ( 25653796 )
2013
3
Ectoparasitic infestations. ( 16107235 )
2005
4
Ectoparasitic infestations in homeless children. ( 12748918 )
2003
5
Anogenital lesions (viral diseases and ectoparasitic infestations): unapproved treatments. ( 12490361 )
2002
6
Parasitic infections & ectoparasitic infestations. ( 11362602 )
1995
7
Unusual arthropod ectoparasitic infestations of man. ( 4015540 )
1985
8
The young pig. Ectoparasitic infestations. ( 6067941 )
1967
Sources

Variations for Parasitic Ectoparasitic Infectious Disease

About this section
Sources

Expression for Parasitic Ectoparasitic Infectious Disease

About this section
Search GEO for disease gene expression data for Parasitic Ectoparasitic Infectious Disease.
Sources

Pathways for Parasitic Ectoparasitic Infectious Disease

About this section
Sources

GO Terms for Parasitic Ectoparasitic Infectious Disease

About this section
Sources

Sources for Parasitic Ectoparasitic Infectious Disease

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....