MCID: PRS034
MIFTS: 53

Parasitic Helminthiasis Infectious Disease

Categories: Gastrointestinal diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Parasitic Helminthiasis Infectious Disease

MalaCards integrated aliases for Parasitic Helminthiasis Infectious Disease:

Name: Parasitic Helminthiasis Infectious Disease 12 15
Helminthiasis 12 76 53 55 44 73
Intestinal Helminthiasis 53 73
Helminth Infection 12
Worm Infections 53
Worm Infection 12
Helminthosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:883
ICD10 33 B65-B83 B83.9
MeSH 44 D006373
NCIt 50 C84751
SNOMED-CT 68 27601005

Summaries for Parasitic Helminthiasis Infectious Disease

Disease Ontology : 12 A parasitic infectious disease that occurs when part of the body is infested with parasitic worms such as cestodes, nematodes and trematodes.

MalaCards based summary : Parasitic Helminthiasis Infectious Disease, also known as helminthiasis, is related to coenurosis and angiostrongyliasis. An important gene associated with Parasitic Helminthiasis Infectious Disease is IL5 (Interleukin 5), and among its related pathways/superpathways are PAK Pathway and Allograft rejection. Affiliated tissues include testes, lung and skin, and related phenotypes are homeostasis/metabolism and digestive/alimentary

Wikipedia : 76 Helminthiasis, also known as worm infection, is any macroparasitic disease of humans and other animals... more...

Related Diseases for Parasitic Helminthiasis Infectious Disease

Diseases related to Parasitic Helminthiasis Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 263)
# Related Disease Score Top Affiliating Genes
1 coenurosis 32.4 MT-CO1 MT-ND1
2 angiostrongyliasis 32.3 IL13 IL4 IL5
3 enterobiasis 32.3 IL13 IL4 IL5
4 ascaridiasis 32.2 IL10 IL13 STH
5 paragonimiasis 32.2 IL13 IL5 MT-CO1 RNASE3
6 fasciolopsiasis 32.2 CTSL SNAI1
7 sparganosis 32.2 CTSL MT-CO1
8 ancylostomiasis 32.2 EPGN MT-CO1 RNASE3
9 gnathomiasis 32.2 CTSL MT-CO1 SNAI1
10 necatoriasis 32.2 EPGN IL10 IL5
11 taeniasis 32.1 CTSL IL10 MT-CO1 MT-ND1
12 filariasis 32.1 IL10 IL5 TLR9 TNF
13 trichuriasis 32.0 IL10 IL13 RNASE3 STH TNF
14 schistosomiasis 31.9 IL10 IL13 IL4 IL5 RNASE3 TNF
15 echinococcosis 31.8 CES1 IL10 IL5 MT-CO1 MT-ND1 TNF
16 elephantiasis 31.7 GPT2 MFF RNASE3 SRCIN1
17 intestinal disease 30.4 IL10 TLR9 TNF TRPV1
18 allergic asthma 30.3 IL10 IL13 IL4 IL5 RNASE3
19 onchocerciasis 30.3 IL13 IL4 IL5 RNASE3
20 hypereosinophilic syndrome 30.3 IL13 IL4 IL5 RNASE3
21 colitis 30.2 IL10 IL4 TLR9 TNF
22 asthma 30.2 IL10 IL13 IL4 IL5 RNASE3 TLR9
23 dermatitis 30.2 IL13 IL4 IL5 TLR9 TRPV1
24 plasmodium falciparum malaria 30.2 IL10 TLR9 TNF
25 pulmonary tuberculosis 30.1 IL10 IL4 TLR9 TNF
26 endomyocardial fibrosis 30.1 IL10 IL4 TNF
27 malaria 30.1 IL10 IL13 IL4 IL5 MT-CO1 TLR9
28 filarial elephantiasis 30.1 GPT2 IL10 IL4 IL5 SRCIN1 STH
29 urinary schistosomiasis 30.1 IL13 IL4 IL5 RNASE3
30 pulmonary eosinophilia 30.1 IL13 IL4 IL5 RNASE3
31 tetanus 30.0 IL10 IL13 IL4 IL5
32 toxoplasmosis 30.0 IL10 IL4 TLR9 TNF
33 human immunodeficiency virus infectious disease 30.0 IL10 TLR9 TNF
34 trypanosomiasis 30.0 IL10 IL4 TLR9 TNF
35 leprosy 3 30.0 IL10 IL4 TNF
36 gastrointestinal system disease 30.0 IL10 TLR9 TNF TRPV1
37 coccidiosis 29.9 IL10 IL4 TLR9 TNF
38 respiratory allergy 29.9 IL10 IL13 IL4 IL5 RNASE3 TLR9
39 autoimmune disease 29.9 IL10 IL4 IL5 TLR9 TNF
40 intestinal schistosomiasis 29.8 CHRM2 IL13 IL4 IL5 SNAI1 SRCIN1
41 multiple sclerosis 29.8 IL10 IL4 IL5 TLR9 TNF
42 dermatitis, atopic 29.8 IL10 IL13 IL4 IL5 RNASE3 TLR9
43 screw worm infectious disease 11.4
44 ascaris lumbricoides infection 11.2
45 philophthalmiasis 11.2
46 mesocestoidiasis 11.2
47 acanthocephaliasis 11.2
48 baylisascariasis 11.2
49 dioctophymiasis 11.2
50 hymenolepiasis 11.2

Graphical network of the top 20 diseases related to Parasitic Helminthiasis Infectious Disease:



Diseases related to Parasitic Helminthiasis Infectious Disease

Symptoms & Phenotypes for Parasitic Helminthiasis Infectious Disease

MGI Mouse Phenotypes related to Parasitic Helminthiasis Infectious Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.73 CES1 CHRM2 EPGN GPT2 IL10 IL13
2 digestive/alimentary MP:0005381 9.7 IL10 IL13 IL4 IL5 SNAI1 TLR9
3 liver/biliary system MP:0005370 9.17 CES1 CHRM2 IL10 IL4 IL5 TNF

Drugs & Therapeutics for Parasitic Helminthiasis Infectious Disease

Search Clinical Trials , NIH Clinical Center for Parasitic Helminthiasis Infectious Disease

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: helminthiasis

Genetic Tests for Parasitic Helminthiasis Infectious Disease

Anatomical Context for Parasitic Helminthiasis Infectious Disease

MalaCards organs/tissues related to Parasitic Helminthiasis Infectious Disease:

41
Testes, Lung, Skin, Bone, Neutrophil, T Cells

Publications for Parasitic Helminthiasis Infectious Disease

Articles related to Parasitic Helminthiasis Infectious Disease:

(show top 50) (show all 140)
# Title Authors Year
1
A retrospective administrative database analysis of the association between clonorchiasis or helminthiasis and the development of cholelithiasis. ( 30071748 )
2018
2
Association of water quality with soil-transmitted helminthiasis and diarrhea in Nueva Santa Rosa, Guatemala, 2010. ( 30285954 )
2018
3
Baseline Mapping of Schistosomiasis and Soil Transmitted Helminthiasis in the Northern and Eastern Health Regions of Gabon, Central Africa: Recommendations for Preventive Chemotherapy. ( 30423901 )
2018
4
Prospects for the elimination of schistosomiasis and soil-transmitted helminthiasis: exploring disease trends through time at the Barombi crater lakes, South-West Cameroon. ( 30246664 )
2018
5
Tailoring Water, Sanitation, and Hygiene (WASH) Targets for Soil-Transmitted Helminthiasis and Schistosomiasis Control. ( 29055522 )
2018
6
Interrupting seasonal transmission of Schistosoma haematobium and control of soil-transmitted helminthiasis in northern and central Côte d'Ivoire: a SCORE study protocol. ( 29378542 )
2018
7
Risk Factors for Soil-Transmitted Helminthiasis in Preschool Children Living in Farmland, North Sumatera, Indonesia. ( 29849666 )
2018
8
Preventive Chemotherapy in the Fight against Soil-Transmitted Helminthiasis: Achievements and Limitations. ( 29858018 )
2018
9
Impact of a national deworming campaign on the prevalence of soil-transmitted helminthiasis in Uganda (2004-2016): Implications for national control programs. ( 29975696 )
2018
10
Toward the 2020 goal of soil-transmitted helminthiasis control and elimination. ( 30106975 )
2018
11
A community-based surveillance of gastrointestinal helminthiasis among pregnant women in Ibadan, South West Nigeria. ( 30297573 )
2018
12
Assessment of the burden of soil-transmitted helminthiasis after five years of mass drug administration for Onchocerciasis and Lymphatic filariasis in Kebbi State, Nigeria. ( 29774278 )
2017
13
Schistosomiasis, intestinal helminthiasis and nutritional status among preschool-aged children in sub-urban communities of Abeokuta, Southwest, Nigeria. ( 29183397 )
2017
14
Initiating NTD programs targeting schistosomiasis and soil-transmitted helminthiasis in two provinces of the Democratic Republic of the Congo: Establishment of baseline prevalence for mass drug administration. ( 27888125 )
2017
15
A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now. ( 27914852 )
2017
16
Soil-Transmitted Helminthiasis and Schistosomiasis in Children of Poor Families in Leyte, Philippines: Lessons for Disease Prevention and Control. ( 28115576 )
2017
17
Urogenital schistosomiasis and soil-transmitted helminthiasis (STH) in Cameroon: An epidemiological update at Barombi Mbo and Barombi Kotto crater lakes assessing prospects for intensified control interventions. ( 28238285 )
2017
18
Schistosomiasis and soil-transmitted helminthiasis in Rwanda: an update on their epidemiology and control. ( 28245883 )
2017
19
Geo-helminthiasis among migrants in Sicily: a possible focus for re-emerging neurocysticercosis in Europe. ( 28289849 )
2017
20
Erratum to: Geo-helminthiasis among migrants in Sicily: A possible focus for re-emerging neurocysticercosis in Europe. ( 28421303 )
2017
21
Health informatics model for helminthiasis in Thailand. ( 27666946 )
2017
22
Soil transmitted helminthiasis in indigenous groups. A community cross sectional study in the Amazonian southern border region of Ecuador. ( 28292765 )
2017
23
Helminthiasis characterization and anthelmintic efficacy for ewes and lambs raised in tropical semiarid region. ( 28352962 )
2017
24
Epidemiology of intestinal helminthiasis among school children with emphasis on Schistosoma mansoni infection in Wolaita zone, Southern Ethiopia. ( 28633651 )
2017
25
Soil transmitted Helminthiasis and associated risk factors among elementary school children in ambo town, western Ethiopia. ( 29017470 )
2017
26
Soil transmitted helminthiasis in different occupational groups in Swat, Khyber Pakhtunkhwa, Pakistan. ( 29039336 )
2017
27
Laboratory diagnosis of soil transmitted helminthiasis. ( 29114485 )
2017
28
Preventive chemotherapy to control soil-transmitted helminthiasis averted more than 500 000 DALYs in 2015. ( 29346640 )
2017
29
Accuracy of Coverage Survey Recall following an Integrated Mass Drug Administration for Lymphatic Filariasis, Schistosomiasis, and Soil-Transmitted Helminthiasis. ( 26766287 )
2016
30
Assessment of global guidelines for preventive chemotherapy against schistosomiasis and soil-transmitted helminthiasis: a cost-effectiveness modelling study. ( 27286968 )
2016
31
Equitable control of schistosomiasis and helminthiasis. ( 27286969 )
2016
32
Soil-Transmitted Helminthiasis and Vitamin A Deficiency: Two Problems, One Policy. ( 26724966 )
2016
33
High prevalence of cannabis use among Aka foragers of the Congo Basin and its possible relationship to helminthiasis. ( 26031406 )
2016
34
Cost-effectiveness of community-wide treatment for helminthiasis--Authors' reply. ( 26848087 )
2016
35
Cost-effectiveness of community-wide treatment for helminthiasis. ( 26848088 )
2016
36
Soil-transmitted Helminthiasis in India. ( 27079446 )
2016
37
Rationale for Quality Assurance in Fecal Egg Monitoring of Soil-Transmitted Helminthiasis. ( 27352875 )
2016
38
In Vitro and In Vivo Drug Interaction Study of Two Lead Combinations, Oxantel Pamoate plus Albendazole and Albendazole plus Mebendazole, for the Treatment of Soil-Transmitted Helminthiasis. ( 27480864 )
2016
39
Comparison of community-wide, integrated mass drug administration strategies for schistosomiasis and soil-transmitted helminthiasis: a cost-effectiveness modelling study. ( 26385302 )
2015
40
Patterns and Risk Factors of Soil-Transmitted Helminthiasis Among Orang Asli Subgroups in Peninsular Malaysia. ( 26055746 )
2015
41
Home Healthcare Program for Soil-Transmitted Helminthiasis in Schoolchildren along the Mekong River Basin. ( 26201127 )
2015
42
Comparison of Kato-Katz thick-smear and McMaster egg counting method for the assessment of drug efficacy against soil-transmitted helminthiasis in school children in Jimma Town, Ethiopia. ( 26385937 )
2015
43
School-based control of soil-transmitted helminthiasis in western Visayas, Philippines. ( 24974639 )
2014
44
Intestinal helminthiasis in children with chronic neurological disorders in Benin City, Nigeria: intensity and behavioral risk factors. ( 23275106 )
2013
45
Intestinal helminthiasis and nutritional status of children living in orphanages in Benin City, Nigeria. ( 23563470 )
2013
46
Prevalence and intensity of intestinal helminthiasis in children living in orphanages in Benin City, Nigeria. ( 23362620 )
2012
47
Prevalence and predictors of intestinal helminthiasis among school children in jimma zone; a cross-sectional study. ( 22434996 )
2011
48
Intestinal helminthiasis in children of gurez valley of jammu and kashmir state, India. ( 20606959 )
2010
49
Prevalence and management of intestinal helminthiasis among HIV-infected patients at Muhimbili National Hospital. ( 20530468 )
2010
50
Some behavioural risk factors for intestinal helminthiasis in nursery and primary school children in Enugu, south eastern Nigeria. ( 20857787 )
2010

Variations for Parasitic Helminthiasis Infectious Disease

Expression for Parasitic Helminthiasis Infectious Disease

Search GEO for disease gene expression data for Parasitic Helminthiasis Infectious Disease.

Pathways for Parasitic Helminthiasis Infectious Disease

Pathways related to Parasitic Helminthiasis Infectious Disease according to GeneCards Suite gene sharing:

(show all 29)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.21 IL10 IL13 IL4 IL5 SNAI1 TNF
2
Show member pathways
12.76 CTSL IL10 IL13 IL4 IL5 RNASE3
3
Show member pathways
12.49 IL10 IL13 IL4 IL5 TNF
4
Show member pathways
12.34 IL10 IL4 IL5 TNF
5
Show member pathways
12.31 IL10 IL13 IL4 IL5
6
Show member pathways
12.24 IL13 IL4 IL5 TNF
7
Show member pathways
12.16 IL10 IL13 IL4 IL5 TNF
8
Show member pathways
12.09 CTSL IL4 TLR9 TNF
9 12.08 CHRM2 IL10 IL13 TNF
10
Show member pathways
11.93 CTSL IL13 IL4 TNF
11 11.88 IL10 IL4 IL5 TNF
12 11.85 IL10 IL13 IL4 TNF
13 11.8 IL4 IL5 TNF
14 11.71 IL13 IL4 IL5
15
Show member pathways
11.67 IL4 IL5 TNF
16 11.66 IL10 TLR9 TNF
17 11.59 IL10 IL13 IL4 TNF
18 11.57 IL10 IL4 IL5
19 11.5 IL13 IL4 IL5 TNF
20 11.45 IL10 TLR9 TNF
21 11.36 IL10 IL13 IL4 TNF
22 11.29 IL10 IL13 IL4 IL5
23 11.26 IL10 TLR9 TNF
24 11.26 IL10 IL13 IL4 IL5 TNF
25 11.09 IL10 IL13 IL4 IL5 TNF
26 11.06 IL13 IL4 IL5 TNF
27 10.93 IL10 IL13 IL4 IL5 TNF
28 10.87 IL10 IL13 IL4 IL5
29 10.48 IL10 IL13 IL4 IL5 TNF

GO Terms for Parasitic Helminthiasis Infectious Disease

Cellular components related to Parasitic Helminthiasis Infectious Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CTSL EPGN IL10 IL13 IL4 IL5
2 extracellular space GO:0005615 9.28 CES1 CTSL EPGN IL10 IL13 IL4

Biological processes related to Parasitic Helminthiasis Infectious Disease according to GeneCards Suite gene sharing:

(show all 24)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.97 IL10 IL13 IL4 IL5 TNF
2 defense response to bacterium GO:0042742 9.88 IL10 RNASE3 TLR9 TNF
3 immune response GO:0006955 9.8 IL10 IL13 IL4 IL5 TLR9 TNF
4 cytokine-mediated signaling pathway GO:0019221 9.77 IL10 IL13 IL4 IL5 TNF
5 negative regulation of endothelial cell apoptotic process GO:2000352 9.63 IL10 IL13 IL4
6 positive regulation of macrophage activation GO:0043032 9.62 IL10 IL13
7 negative regulation of growth of symbiont in host GO:0044130 9.61 IL10 TNF
8 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.61 IL10 TNF
9 positive regulation of podosome assembly GO:0071803 9.6 IL5 TNF
10 response to molecule of bacterial origin GO:0002237 9.59 IL10 TLR9
11 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.58 TLR9 TNF
12 endothelial cell apoptotic process GO:0072577 9.56 IL10 TNF
13 positive regulation of immunoglobulin production GO:0002639 9.55 IL13 TLR9
14 negative regulation of interleukin-8 production GO:0032717 9.54 IL10 TLR9
15 positive regulation of MHC class II biosynthetic process GO:0045348 9.52 IL10 IL4
16 negative regulation of cytokine secretion involved in immune response GO:0002740 9.51 IL10 TNF
17 regulation of isotype switching GO:0045191 9.49 IL10 IL4
18 type 2 immune response GO:0042092 9.48 IL10 IL4
19 negative regulation of complement-dependent cytotoxicity GO:1903660 9.43 IL13 IL4
20 negative regulation of interleukin-6 production GO:0032715 9.43 IL10 TLR9 TNF
21 inflammatory response GO:0006954 9.43 IL10 IL13 IL5 TLR9 TNF TRPV1
22 receptor biosynthetic process GO:0032800 9.4 IL10 TNF
23 microglial cell activation GO:0001774 9.33 IL13 TNF TRPV1
24 positive regulation of B cell proliferation GO:0030890 8.92 IL13 IL4 IL5 TLR9

Molecular functions related to Parasitic Helminthiasis Infectious Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.26 EPGN IL10 IL4 IL5
2 cytokine activity GO:0005125 9.02 IL10 IL13 IL4 IL5 TNF

Sources for Parasitic Helminthiasis Infectious Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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