MCID: PRS035
MIFTS: 23

Parasitic Ichthyosporea Infectious Disease

Categories: Infectious diseases

Aliases & Classifications for Parasitic Ichthyosporea Infectious Disease

MalaCards integrated aliases for Parasitic Ichthyosporea Infectious Disease:

Name: Parasitic Ichthyosporea Infectious Disease 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050291

Summaries for Parasitic Ichthyosporea Infectious Disease

Disease Ontology : 12 A parasitic infectious disease that involves parasitic infection by the members of the class Ichthyosporea, which are parasites of fish and other animals.

MalaCards based summary : Parasitic Ichthyosporea Infectious Disease is related to rhinosporidiosis and orbit lymphoma. An important gene associated with Parasitic Ichthyosporea Infectious Disease is TIA1 (TIA1 Cytotoxic Granule Associated RNA Binding Protein), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. Related phenotypes are Decreased viability and Decreased viability

Related Diseases for Parasitic Ichthyosporea Infectious Disease

Diseases related to Parasitic Ichthyosporea Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 187)
# Related Disease Score Top Affiliating Genes
1 rhinosporidiosis 27.3 VGF TIA1 SERPINA1 NRL NCAM1 IL4
2 orbit lymphoma 10.4 TIA1 NCAM1
3 systemic epstein-barr virus-positive t-cell lymphoma of childhood 10.4 TIA1 NCAM1
4 bacterial esophagitis 10.4 CD68 CD4
5 xanthogranulomatous pyelonephritis 10.4 CD68 AOAH
6 cork-handlers' disease 10.4 CD8A CD4
7 necrotic uveal melanoma 10.4 CD8A CD4
8 lichen sclerosus et atrophicus 10.4 TIA1 CD8A
9 lethal midline granuloma 10.4 TIA1 NCAM1
10 granulomatous myositis 10.4 CD8A CD68
11 early yaws 10.4 CD8A CD4
12 ventilation pneumonitis 10.4 CD8A CD4
13 diffuse infiltrative lymphocytosis syndrome 10.4 CD8A CD4
14 latent syphilis 10.4 CD8A CD4
15 lymphocytic gastritis 10.4 TIA1 CD8A
16 orbital cellulitis 10.4 NCAM1 CD4
17 type 1 diabetes mellitus 23 10.4 CD8A CD4
18 acute orbital inflammation 10.4 NCAM1 CD4
19 autoimmune lymphoproliferative syndrome, type iia 10.4 CD8A CD4
20 lymphohistiocytoid mesothelioma 10.4 CD8A CD68
21 parapsoriasis 10.4 CD8A CD4
22 gastroduodenitis 10.4 CD8A CD4
23 geniculate ganglionitis 10.4 IFNA2 CD4
24 primary syphilis 10.4 CD8A CD4
25 lymphomatoid granulomatosis 10.4 TIA1 IFNA2
26 norwegian scabies 10.4 CD8A CD4
27 bird fancier's lung 10.4 CD8A CD4
28 conjunctival pigmentation 10.4 IFNA2 CD68
29 skin sarcoidosis 10.3 CD8A CD4
30 nasal cavity lymphoma 10.3 TIA1 NCAM1
31 variola major 10.3 CD8A CD4
32 granuloma annulare 10.3 CD68 CD4
33 tertiary syphilis 10.3 CD8A CD4
34 spongiotic dermatitis 10.3 CD8A CD4
35 acute retinal necrosis syndrome 10.3 CD8A CD4
36 congenital granular cell tumor 10.3 SERPINA1 CD68
37 maxillary sinus inverted papilloma 10.3 DNASE1 CD8A
38 liver sarcoma 10.3 SERPINA1 CD68
39 gastrointestinal lymphoma 10.3 TIA1 NCAM1
40 cerebral lymphoma 10.3 CD8A CD4
41 oral tuberculosis 10.3 CD8A CD4
42 cerebritis 10.3 CD8A CD4
43 invasive malignant thymoma 10.3 CD8A CD4
44 west nile encephalitis 10.3 CD8A CD4
45 granulomatous hepatitis 10.3 CD8A CD4
46 virus associated hemophagocytic syndrome 10.3 IL4 CD68
47 t-cell adult acute lymphocytic leukemia 10.3 TIA1 CD8A CD4
48 giardiasis 10.3 TIA1 CD8A CD4
49 granulomatous dermatitis 10.3 CD8A CD68 CD4
50 orchitis 10.3 CD8A CD68 CD4

Graphical network of the top 20 diseases related to Parasitic Ichthyosporea Infectious Disease:



Diseases related to Parasitic Ichthyosporea Infectious Disease

Symptoms & Phenotypes for Parasitic Ichthyosporea Infectious Disease

GenomeRNAi Phenotypes related to Parasitic Ichthyosporea Infectious Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-1 9.53 NCAM1
2 Decreased viability GR00240-S-1 9.53 TIA1
3 Decreased viability GR00249-S 9.53 IFNA21 TIA1
4 Decreased viability GR00342-S-2 9.53 CD4
5 Decreased viability GR00381-A-1 9.53 APOF CLEC7A TIA1
6 Decreased viability GR00381-A-2 9.53 CLEC7A
7 Decreased viability GR00381-A-3 9.53 APOF
8 Decreased viability GR00386-A-1 9.53 IFNA17 VGF
9 Decreased viability GR00402-S-2 9.53 APOF BMP2 CD8A IFNA21

MGI Mouse Phenotypes related to Parasitic Ichthyosporea Infectious Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.36 AOAH BMP2 CD4 CD68 CD8A CLEC7A

Drugs & Therapeutics for Parasitic Ichthyosporea Infectious Disease

Search Clinical Trials , NIH Clinical Center for Parasitic Ichthyosporea Infectious Disease

Genetic Tests for Parasitic Ichthyosporea Infectious Disease

Anatomical Context for Parasitic Ichthyosporea Infectious Disease

Publications for Parasitic Ichthyosporea Infectious Disease

Variations for Parasitic Ichthyosporea Infectious Disease

Expression for Parasitic Ichthyosporea Infectious Disease

Search GEO for disease gene expression data for Parasitic Ichthyosporea Infectious Disease.

Pathways for Parasitic Ichthyosporea Infectious Disease

Pathways related to Parasitic Ichthyosporea Infectious Disease according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.81 SERPINA1 NCAM1 IL4 IFNA21 IFNA2 IFNA17
2
Show member pathways
13.11 NCAM1 IL4 IFNA21 IFNA2 IFNA17 FN1
3 12.52 IL4 IFNA21 IFNA2 IFNA17 FN1 BMP2
4
Show member pathways
12.48 IL4 IFNA21 IFNA2 IFNA17 CD8A CD4
5
Show member pathways
12.32 IL4 IFNA21 IFNA2 IFNA17
6
Show member pathways
12.19 IL4 IFNA21 IFNA2 IFNA17
7 11.99 IFNA21 IFNA2 IFNA17 CLEC7A
8
Show member pathways
11.98 IL4 IFNA21 IFNA2 IFNA17 BMP2
9 11.71 IL4 CD8A CD4
10 11.68 NCAM1 FN1 BMP2
11 11.65 IFNA21 IFNA2 IFNA17
12 11.36 NCAM1 IL4 CD8A CD4
13 11.25 IFNA21 IFNA2 IFNA17
14 11.16 NCAM1 IL4 IFNA2 CD8A CD68 CD4
15 11.13 NCAM1 IFNA2 CD8A CD4

GO Terms for Parasitic Ichthyosporea Infectious Disease

Cellular components related to Parasitic Ichthyosporea Infectious Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.63 NCAM1 DUOX2 DUOX1 CLEC7A CD4 BMP2
2 extracellular space GO:0005615 9.61 VGF SERPINA1 IL4 IFNA21 IFNA2 IFNA17
3 extracellular region GO:0005576 9.44 VGF SERPINA1 NCAM1 IL4 IFNA21 IFNA2
4 NADPH oxidase complex GO:0043020 9.26 DUOX2 DUOX1

Biological processes related to Parasitic Ichthyosporea Infectious Disease according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.98 NRL IL4 FN1 CLEC7A BMP2
2 adaptive immune response GO:0002250 9.97 IFNA21 IFNA2 IFNA17 CD8A CD4
3 blood coagulation GO:0007596 9.84 SERPINA1 IFNA21 IFNA2 IFNA17
4 type I interferon signaling pathway GO:0060337 9.72 IFNA21 IFNA2 IFNA17
5 humoral immune response GO:0006959 9.7 IFNA21 IFNA2 IFNA17
6 response to cAMP GO:0051591 9.69 VGF DUOX2 DUOX1
7 response to exogenous dsRNA GO:0043330 9.67 IFNA21 IFNA2 IFNA17
8 B cell proliferation GO:0042100 9.65 IFNA21 IFNA2 IFNA17
9 positive regulation of wound healing GO:0090303 9.61 DUOX2 DUOX1 CLEC7A
10 hormone biosynthetic process GO:0042446 9.58 DUOX2 DUOX1
11 T cell activation involved in immune response GO:0002286 9.58 IFNA21 IFNA2 IFNA17
12 hydrogen peroxide biosynthetic process GO:0050665 9.56 DUOX2 DUOX1
13 B cell differentiation GO:0030183 9.56 IL4 IFNA21 IFNA2 IFNA17
14 defense response GO:0006952 9.55 IFNA21 IFNA2 IFNA17 DUOX2 DUOX1
15 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 9.54 IFNA21 IFNA2 IFNA17
16 natural killer cell activation involved in immune response GO:0002323 9.5 IFNA21 IFNA2 IFNA17
17 cuticle development GO:0042335 9.46 DUOX2 DUOX1
18 T cell activation GO:0042110 9.26 IL4 CLEC7A CD8A CD4
19 cytokine-mediated signaling pathway GO:0019221 9.23 IL4 IFNA21 IFNA2 IFNA17 FN1 DUOX2

Molecular functions related to Parasitic Ichthyosporea Infectious Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.55 IL4 IFNA21 IFNA2 IFNA17 BMP2
2 superoxide-generating NADPH oxidase activity GO:0016175 9.32 DUOX2 DUOX1
3 NAD(P)H oxidase activity GO:0016174 9.26 DUOX2 DUOX1
4 type I interferon receptor binding GO:0005132 9.13 IFNA21 IFNA2 IFNA17
5 cytokine receptor binding GO:0005126 8.92 IL4 IFNA21 IFNA2 IFNA17

Sources for Parasitic Ichthyosporea Infectious Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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