Parasitic Protozoa Infectious Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: PRS036 MIFTS: 44	Parasitic Protozoa Infectious Disease Categories: Cancer diseases, Infectious diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Parasitic Protozoa Infectious Disease

MalaCards integrated aliases for Parasitic Protozoa Infectious Disease:

Name: Parasitic Protozoa Infectious Disease ¹² ¹⁵

Protozoan Infections ⁴⁴ ⁷¹

Sarcomastigophora Infectious Disease ¹²

Mastigophora Infectious Disease ¹²

Classifications:

MalaCards categories:
Global: Infectious diseases Cancer diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Certain infectious and parasitic diseases

Protozoal diseases

Unspecified protozoal disease

External Ids:

Disease Ontology ¹² DOID:2789

MeSH ⁴⁴ D011528

NCIt ⁵⁰ C34953

SNOMED-CT ⁶⁷ 95896000

ICD10 ³² B64

UMLS ⁷¹ C0033740

Sources

Summaries for Parasitic Protozoa Infectious Disease

Disease Ontology : ¹² A parasitic infectious disease that is caused by parasitic protozoa which are microorganisms classified as unicellular eukaryotes.

MalaCards based summary : Parasitic Protozoa Infectious Disease, also known as protozoan infections, is related to babesiosis and giardiasis. An important gene associated with Parasitic Protozoa Infectious Disease is H2AC18 (H2A Clustered Histone 18), and among its related pathways/superpathways are PAK Pathway and Allograft rejection. The drugs Albendazole and Anthelmintics have been mentioned in the context of this disorder. Affiliated tissues include kidney, small intestine and skin, and related phenotype is integument.

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Related Diseases for Parasitic Protozoa Infectious Disease

Diseases related to Parasitic Protozoa Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 797)

#	Related Disease	Score	Top Affiliating Genes
1	babesiosis	32.8	MT-CYB IL10 CD4 ALB
2	giardiasis	32.8	IL10 CD8A CD4 ALB
3	amebiasis	32.8	TNF IL4 IL10 CD4 ALB
4	leishmaniasis	32.7	TNF LMLN IL6 IL4 IL2 IL10
5	trichomoniasis	32.7	TNF LMLN IL6 IL2 IL10 CD4
6	trypanosomiasis	32.7	TNF IL6 IL4 IL10 H2AC18 ALB
7	coccidiosis	32.4	TNF MT-CYB IL6 IL4 IL2 IL10
8	malaria	32.3	TNF SERPINA3 MT-CYB IL6 IL4 IL2
9	toxoplasmosis	31.6	TNF IL6 IL4 IL10 DHFR
10	cryptosporidiosis	31.4	DHFR CD8A CD4
11	diarrhea	31.2	TNF IL6 IL2 IL10 ALB
12	chagas disease	31.1	TNF IL6 IL4 IL2 IL10 CD4
13	dysentery	31.0	TNF IL6 IL10 H2AC18 CD4 CCR6
14	acquired immunodeficiency syndrome	31.0	TNF IL6 IL2 IL10 CD4 CCR6
15	parasitic helminthiasis infectious disease	30.9	TNF SIGLEC5 SERPINA3 IL6 IL4 IL2
16	myocarditis	30.9	TNF IL6 IL4 IL2 IL10
17	gastroenteritis	30.9	TNF IL6 IL4 IL10 ALB
18	acute myocarditis	30.8	TNF IL10 H2AC18 CD4
19	respiratory allergy	30.8	IL4 IL10 ICOSLG CD4 CCR6
20	echinococcosis	30.7	TNF IL6 IL10 CD8A
21	schistosomiasis	30.7	TNF IL4 IL2 IL10 ALB
22	sleeping sickness	30.7	PRODH LMLN IL6 IL10 H2AC18
23	typhoid fever	30.7	TNF SIGLEC5 IL6 CCR6 ALB
24	proteasome-associated autoinflammatory syndrome 1	30.7	TNF IL6 IL4 IL10 ALB
25	visceral leishmaniasis	30.7	TNF LMLN IL4 IL2 IL10 ALB
26	bacterial infectious disease	30.7	TNF SERPINA3 IL6 IL10 ICOSLG H2AC18
27	meningoencephalitis	30.6	TNF SERPINA3 IL6 IL10 CD8A CD4
28	pneumocystosis	30.6	TNF MT-CYB IL6 IL2 DHFR CD8A
29	colorectal cancer	30.2	TNF SERPINA3 MT-CYB IL6 IL4 IL2
30	primary amebic meningoencephalitis	11.3
31	granulomatous amebic encephalitis	11.3
32	balantidiasis	11.3
33	theileriasis	11.3
34	dientamoebiasis	11.3
35	elephantiasis	10.6	IL4 IL10 CD4
36	adult acute lymphocytic leukemia	10.6	CD8A CD4 CCR6
37	tropical endomyocardial fibrosis	10.6	TNF IL4 IL10
38	endomyocardial fibrosis	10.6	TNF IL4 IL10
39	enterocolitis	10.6	TNF IL6 IL10
40	cork-handlers' disease	10.6	CD8A CD4 ALB
41	esophageal candidiasis	10.6	CD8A CD4 CCR6
42	type 1 diabetes mellitus 23	10.6	TNF CD8A CD4
43	punctate inner choroidopathy	10.6	TNF IL10
44	subcutaneous mycosis	10.6	IL10 CD4 CCR6
45	oral hairy leukoplakia	10.6	IL10 CD8A CD4
46	cerebritis	10.6	TNF CD8A CD4
47	viral exanthem	10.6	TNF CD8A CD4
48	immunodeficiency 16	10.6	ICOSLG CD8A CD4 CCR6
49	loiasis	10.6	IL4 IL10 CD4
50	granulomatous dermatitis	10.6	TNF CD8A CD4

Graphical network of the top 20 diseases related to Parasitic Protozoa Infectious Disease:

Sources

Symptoms & Phenotypes for Parasitic Protozoa Infectious Disease

MGI Mouse Phenotypes related to Parasitic Protozoa Infectious Disease:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	integument	MP:0010771	9.28	CD4 CD8A DHFR IL10 IL4 IL6

Sources

Drugs & Therapeutics for Parasitic Protozoa Infectious Disease

Drugs for Parasitic Protozoa Infectious Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 23)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Albendazole

Approved, Vet_approved

Phase 3

54965-21-8

2082

Synonyms:

((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle

((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle [French]

(5-(Propylthio)-1H-benzimidazol-2-yl)carbamate methyl ester

(5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester

(5-(Propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester

(5-Propylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester

[5-(Propylthio)benzimidazol-2-yl]carbamic Acid Methyl Ester

[5-(Propythio)-1H-benzimidazol-2-yl]carbamic acid methyl ester

5-(propylthio)-2-carbomethoxyaminobenzimidazole

5-(Propylthio)-2-carbomethoxyaminobenzimidazole

54965-21-8

A4673_FLUKA

A4673_SIGMA

AB00052377

AC-015

AC1L1CVL

AC1Q2YKD

AKOS000540882

Albendazol

Albendazol [INN-Spanish]

albendazole

Albendazole

Albendazole (JAN/USP/INN)

Albendazole [USAN:INN:BAN:JAN]

Albendazole armstrong brand

Albendazole Armstrong Brand

Albendazole diba brand

Albendazole Diba Brand

Albendazole fustery brand

Albendazole Fustery Brand

Albendazole hormona brand

Albendazole Hormona Brand

Albendazole liferpal brand

Albendazole Liferpal Brand

Albendazole monohydrochloride

Albendazole Monohydrochloride

Albendazole Noe-Socopharm Brand

Albendazole noé-socopharm brand

Albendazole pfizer brand

Albendazole Pfizer Brand

Albendazole sanicoopa brand

Albendazole Sanicoopa Brand

Albendazole valdecasas brand

Albendazole Valdecasas Brand

Albendazolum

Albendazolum [INN-Latin]

Albendoral

Albenza

Albenza (TN)

Albenza, Eskazole, Zentel, Andazol, Albendazole

Andazol

Armstrong brand OF albendazole

Armstrong Brand of Albendazole

BAS 00439961

BB_SC-1386

Bendapar

BIDD:GT0615

Bilutac

BIM-0051849.0001

BPBio1_000038

BRD-K79131256-001-04-7

BSPBio_000034

BSPBio_002548

C01779

CARBAMIC ACID, (5-(PROPYLTHIO)-1H-BENZIMIDAZOL-2-YL)-, METHYL ESTER

Carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester

CAS-54965-21-8

CHEBI:16664

CHEBI:506787

CHEMBL1483

ChemDiv1_000190

ChemDivAM_000003

CID2082

CPD000036735

D00134

D015766

DB00518

Diba brand OF albendazole

Diba Brand of Albendazole

Digezanol

Disthelm

Disthelm, mediamix V

Disthelm, Mediamix V

DivK1c_000704

EINECS 259-414-7

Endoplus

Eskazole

Fustery brand OF albendazole

Fustery Brand of Albendazole

Gascop

HMS1568B16

HMS1922K04

HMS2090G19

HMS2093K13

HMS502D06

HMS587I14

Hormona brand OF albendazole

Hormona Brand of Albendazole

HSDB 7444

I01-0380

IDI1_000704

InChI=1/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

KBio1_000704

KBio2_002012

KBio2_004580

KBio2_007148

KBioGR_000801

KBioSS_002012

Liferpal brand OF albendazole

Liferpal Brand of Albendazole

LS-50618

Lurdex

Mediamix V disthelm

Mediamix V Disthelm

methyl [(2Z)-5-(propylsulfanyl)-1,3-dihydro-2H-benzimidazol-2-ylidene]carbamate

methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate

methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate

Methyl [5-(Propylthio)benzimidazol-2-yl]carbamate

methyl [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate

Methyl 5-(propylthio)-2-benzimidazolecarbamate

Methyl 5-(propyl-thio)-2-benzimidazolecarbamate

methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate

methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate

Methyl-5-[propylthio]-2-benzimidazole carbamate

Metiazol

MLS000069722

MolPort-000-726-929

MolPort-000-760-571

MolPort-001-932-918

Monohydrochloride, albendazole

Monohydrochloride, Albendazole

NCGC00016876-01

NCGC00016876-02

NCGC00022896-03

NCGC00022896-04

NCGC00022896-05

NCGC00022896-06

NCGC00022896-07

NINDS_000704

Noe Socopharm Brand of Albendazole

Noé socopharm brand OF albendazole

Noe-Socopharm Brand of Albendazole

Noé-socopharm brand OF albendazole

NSC 220008

NSC220008

O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate

O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate

O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamic acid

Oprea1_429292

Oprea1_585016

Oprea1_640007

Pfizer brand OF albendazole

Pfizer Brand of Albendazole

Prestwick_675

Prestwick0_000247

Prestwick1_000247

Prestwick2_000247

Prestwick3_000247

Proftril

S1640_Selleck

SAM002589939

Sanicoopa brand OF albendazole

Sanicoopa Brand of Albendazole

SK And F 62979

SK And F62979

SK And F-62979

SK&F 62979

SK&F62979

SK&F-62979

SKF 62979

SKF62979

SKF-62979

Smith Kline & French Brand of Albendazole

SmithKline beecham brand OF albendazole

SmithKline Beecham Brand of Albendazole

SMR000036735

SPBio_002253

Spectrum_001532

SPECTRUM1503903

Spectrum4_000201

Spectrum5_001567

STK387550

STL046130

STOCK2S-67946

TL8003543

UNII-F4216019LN

V Disthelm, mediamix

V Disthelm, Mediamix

Valbazen

Valdecasas brand OF albendazole

Valdecasas Brand of Albendazole

VU0239747-6

Zental

Zentel

ZINC17146904

Anthelmintics

Phase 3

Antimitotic Agents

Phase 3

Tubulin Modulators

Phase 3

Nitazoxanide

Approved, Investigational, Vet_approved

Phase 1, Phase 2

55981-09-4

41684

Synonyms:

(2-((5-Nitro-2-thiazolyl)carbamoyl)phenyl)acetat

[2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl] acetate

2-(Acetolyloxy)-N-(5-nitro-2-thiazolyl)benzamide

2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate

2-Acetyloxy-N-[(5-nitro-2-thiazolyl)]benzamide

55981-09-4

AC-1302

AC1L26A1

AC1Q5NVY

Alinia

Alinia (TN)

AZT + Nitazoxanide

azt+ nitazoxanide

BRN 1225475

C12H9N3O5S

CHEMBL1401

CID41684

Colufase

Columbia brand 1 OF nitazoxanide

Columbia brand 2 OF nitazoxanide

Columbia brand 3 OF nitazoxanide

CPD000466367

Cryptaz

D02486

Daxon

Daxon, Dexidex, Kidonax, Pacovanton, Paramix, Nitax, Zox, Nitazoxanide

DB00507

EINECS 259-931-8

FT-0082459

Heliton

HMS2051L04

I14-6011

LS-144176

MLS000759492

MLS001424074

MolPort-002-042-244

N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester)

N-(5-Nitrothiazol-2-yl)salicylamide acetate ester

NCGC00090774-01

NCI60_034935

NCIMech_000843

Nitaxozanid

Nitaxozanide

Nitazoxanid

Nitazoxanida

Nitazoxanida [INN-Spanish]

Nitazoxanide

NITAZOXANIDE

Nitazoxanide (USAN/INN)

Nitazoxanide [USAN:INN]

Nitazoxanidum

Nitazoxanidum [INN-Latin]

NSC 697855

NSC697855

NTZ

o-(N-(5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate

Oprea1_263587

Phavic-1

Romark brand 1 OF nitazoxanide

Romark brand 2 OF nitazoxanide

S1627_Selleck

Salicylamide, N-(5-nitro-2-thiazolyl)- acetate (ester)

Salicylamide, N-(5-nitro-2-thiazolyl)-, acetate (ester)

SAM001246708

SBB068315

SMR000466367

STK395664

Taenitaz

Tizoxanide glucuronide

UNII-SOA12P041N

ZINC03956788

Anti-Infective Agents

Phase 1, Phase 2

Antiparasitic Agents

Phase 1, Phase 2

Mesalamine

Phase 1, Phase 2

89-57-6

Anti-Inflammatory Agents

Phase 1, Phase 2

Analgesics, Non-Narcotic

Phase 1, Phase 2

Anti-Inflammatory Agents, Non-Steroidal

Phase 1, Phase 2

Analgesics

Phase 1, Phase 2

Antirheumatic Agents

Phase 1, Phase 2

Artemether

Approved

Phase 1

71963-77-4

119380 9796294 68911

Synonyms:

( )-alpha-Artemether

(1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane

(1R,4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane

(3alpha,5abeta,6beta,8abeta,9alpha,10beta,12beta,12aR*)-isomer of artemether

(3r,5as,6r,8as,9r,10r,12r,12ar)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene

(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine

(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin

(5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene

.beta.-Artemether

.beta.-Dihydroartemisinin methyl ether

.beta.-Methylether of 11-epi-dihydroartemisinin

10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane

10-Methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane

159573-83-8

3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-tri

71939-51-0

71963-77-4

74784-06-8

80286-56-2

93787-85-0

AC1L2APD

AC1L2XO8

AC1L9SH2

AC1L9UV0

AC1MI2ZX

AC1Q6Z74

AC1Q6Z7V

alpha-Artemether

alpha-Dihydroartemisinin methyl ether

AR-1A4424

Arteannuin ether

Artemetero

Artemetero [INN-Spanish]

Artemether

Artemether (INN)

Artemether [INN]

Artemether, (3R-(3alpha,5abeta,6alpha,8abeta,9alpha,10beta,12beta,12ar*))-isomer

Artemether, (3R-(3alpha,5abeta,6beta,8aalpha,9alpha,10beta,12beta,12ar*))-isomer

artemether, (3R-(3alpha,5abeta,6beta,8abeta,9alpha,10alpha,12beta,12aR*))-isomer

Artemether, (3R-(3alpha,5abeta,6beta,8abeta,9alpha,10alpha,12beta,12ar*))-isomer

artemether[inn]

Artemetheri

Artemetherum

Artemetherum [INN-Latin]

Artemisininelactol methyl ether

Artemos

Artenam

Artesaph

Artesian

Artimist

Artmether

b-Artemether

b-Dihydroartemisinin methyl ether

beta-Artemether

beta-Arthemeter

beta-Dihydroartemisinin methyl ether

BRN 5948416

C16H26O5

CHEBI:195280

CHEMBL411864

CHEMBL512315

CID10266705

CID104888

CID3062122

CID456408

CID500199

CID6483308

CID6712286

CID68911

CID9796294

CID9796295

CPD000469218

D02483

DB06697

dihydroartemisinin methyl ether

Dihydroartemisinin methyl ether

Dihydroqinghaosu methyl ether

Dihydroquinghaosu methyl ether

Falcidol

Gvither

HMS2052L09

HSDB 7456

I06-0205

KST-1A8041

LS-176935

LS-64237

Malartem

methyl-dihydroartemisinine

Methyl-dihydroartemisinine

MLS001424249

NCI60_022891

NSC 665970

NSC665970

O-Methyldihydroartemisinine

Paluther

rither

S2264_Selleck

SAM001246799

SM 224

SM 229

SM-224

SMR000469218

UNII-C7D6T3H22J

β-artemether

Β-artemether

β-dihydroartemisinin methyl ether

Β-dihydroartemisinin methyl ether

Lumefantrine

Approved

Phase 1

82186-77-4

6437380

Synonyms:

(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-a-((dibutylamino)methyl)fluorene-4-methanol

(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha((dibutylamino)methyl)fluorene-4-methanol

(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol

(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol

(±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol

120583-69-9

2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol

2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol

2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol

2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol

82186-77-4

AC1O5NKD

AC-4542

benflumetol

Benflumetol

Benflumetol, (-)-isomer

Benflumetol, (+)-isomer

Benflumetol, (+-)-isomer

Bio-0132

C30H32Cl3NO

CHEBI:156095

CHEMBL38827

CID6437380

Coartem

D03821

DB06708

dl-Benflumelol

DL-Benflumelol

HSDB 7210

I14-7746

LS-177674

Lumefantrine

Lumefantrine (INN)

Lumefantrine [INN:BAN]

MolPort-006-394-826

NCGC00167490-01

UNII-F38R0JR742

Antiprotozoal Agents

Phase 1

Antimalarials

Phase 1

Vaccines

Phase 1

Artemether, Lumefantrine Drug Combination

Phase 1

Benzocaine

Approved, Investigational

1994-09-7, 94-09-7

2337

Synonyms:

(p-(Ethoxycarbonyl)phenylamine

06952_FLUKA

112909_ALDRICH

112909_SIAL

1333-08-0

23239-88-5

23239-88-5 (hydrochloride)

4 Aminobenzoic Acid Ethyl Ester

4-(Ethoxycarbonyl)aniline

4-(Ethoxycarbonyl)phenylamine

4-14-00-01129 (Beilstein Handbook Reference)

4-Aminobenzoate

4-Aminobenzoate ethyl ester

4-Aminobenzoic acid

4-aminobenzoic acid ethyl ester

4-amino-benzoic acid ethyl ester

4-Aminobenzoic acid ethyl ester

4-Aminobenzoic acid, ethyl ester

4-Carbethoxyaniline

71123-91-6

94-09-7

94-09-7 (Parent)

A0271

AB00051923

AC1L1DGC

AC1Q341A

AC1Q64JE

Acetate, benzocaine

Acetate, Benzocaine

AE-562/40377256

Aethoform

Aethylium paraminobenzoicum

AI3-02081

AKOS000119763

Amben ethyl ester

Americaine

Anaesthan-syngala

Anaesthesin

Anaesthesinum

Anaesthin

Anestezin

Anestezin [Russian]

Anesthesin

Anesthesine

Anesthone

AR-1H9065

Baby anbesol

Baby Anbesol

BB_SC-0019

Bensokain

Benzoak

Benzocaina

Benzocaina [INN-Spanish]

benzocaine

Benzocaine

Benzocaine (USP/INN)

Benzocaine [INN:BAN]

Benzocaine acetate

Benzocaine Acetate

Benzocaine formate

Benzocaine Formate

Benzocaine hydrobromide

Benzocaine Hydrobromide

Benzocaine hydrochloride

Benzocaine Hydrochloride

Benzocaine methanesulfonate

Benzocaine Methanesulfonate

Benzocainum

Benzocainum [INN-Latin]

Benzoic acid, 4-amino-, ethyl ester

Benzoic acid, 4-amino-, ethyl ester, hydrochloride

Benzoic acid, amino-, ethyl ester

Benzoic acid, p-amino-, ethyl ester

BPBio1_001017

BRD-K75466013-001-05-2

BRN 0638434

BSPBio_000923

BSPBio_001908

C07527

CAS-94-09-7

Caswell No. 430A

CHEBI:116735

CHEMBL278172

Chloraseptic

CID2337

D001566

D00552

DB01086

Dermoplast

Diet ayds

DivK1c_000932

E1501_SIGMA

EINECS 202-303-5

EPA Pesticide Chemical Code 097001

Ethoform

Ethoforme

Ethyl 4-aminobenzoate

Ethyl 4-aminobenzoate hydrochloride

Ethyl 4-aminobenzoic acid

Ethyl aminobenzoate

Ethyl aminobenzoate (JP15)

Ethyl aminobenzoate (VAN)

Ethyl aminobenzoic acid

Ethyl PABA

Ethyl p-aminobenzenecarboxylate

Ethyl p-aminobenzoate

Ethyl p-aminobenzoic acid

Ethyl p-aminophenylcarboxylate

Ethyl p-aminophenylcarboxylic acid

ethylaminobenzoate-4

Ethylester kyseliny p-aminobenzoove

Ethylester kyseliny p-aminobenzoove [Czech]

Ethylis aminobenzoas

ETHYL-P-AMINOBENZOATE

Formate, benzocaine

Formate, Benzocaine

h-4-abz-oet

HMS1570O05

HMS1920G09

HMS2091M11

HMS502O14

HSDB 7225

Hurricaine

Hydrobromide, benzocaine

Hydrobromide, Benzocaine

Hydrochloride, benzocaine

Hydrochloride, Benzocaine

I05-0204

Identhesin

IDI1_000932

KBio1_000932

KBio2_000474

KBio2_003042

KBio2_005610

KBio3_001408

KBioGR_000658

KBioSS_000474

Keloform

LS-35847

Methanesulfonate, benzocaine

Methanesulfonate, Benzocaine

MLS001331704

MLS002153970

MolPort-000-871-526

NCGC00016352-01

NCGC00094598-01

NCGC00094598-02

nchembio.182-comp4

NINDS_000932

Norcain

Norcaine

Norcainum

NSC 122792

NSC 41531

NSC41531

NSC4688

Oprea1_750694

Oprea1_827402

Orabase-b

Ora-jel

Orthesin

Otocain

Outgro

p-(Ethoxycarbonyl)aniline

p-Aminobenzoate

p-Aminobenzoic acid

p-Aminobenzoic acid ethyl ester

p-Aminobenzoic acid, ethyl ester

p-Aminobenzoic ethyl ester

Parathesin

Parathesin (TN)

Parathesine

p-Carbethoxyaniline

p-Ethoxycarboxylic aniline

Prestwick_991

Prestwick0_000712

Prestwick1_000712

Prestwick2_000712

Prestwick3_000712

Slim mint gum

SMR000059025

Solarcaine

Solu H

SPBio_000134

SPBio_002844

Spectrum_000074

SPECTRUM1500139

Spectrum2_000117

Spectrum3_000314

Spectrum4_000249

Spectrum5_000860

STK043620

Topcaine

UNII-U3RSY48JW5

WLN: ZR DVO2

ZINC12358719

tannic acid

Approved

1401-55-4

Calcium, Dietary

Calcium

Nutraceutical

7440-70-2

271

Synonyms:

Ca(2+)

Ca2+

Calcio

Calcium

Calcium element

CALCIUM ion

Calcium(2+)

Calcium, doubly charged positive ion

Calcium, elemental

Elemental calcium

Kalzium

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	A Double-Blind, Placebo-Controlled Trial of Albendazole in HIV-Positive Patients With Intestinal Microsporidiosis	Completed	NCT00002191	Phase 3	Albendazole
2	Role of Intestinal Protozoa and Helminths in the Course of Ulcerative Colitis	Active, not recruiting	NCT03441893	Phase 1, Phase 2	Nitazoxanide 500Mg Oral Tablet;Mesalazine 250Mg Tablet and nitazoxanide 500Mg Oral Tablet;Mesalazine 250Mg
3	Randomized, Double-blind, Placebo-controlled Sequential Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SCYX-7158 After Single Oral Ascending Doses in Healthy Male Volunteers	Completed	NCT01533961	Phase 1	SCYX-7158;Placebo
4	A Single Centre, Open Label, Pilot Phase Ib Study to Investigate Blood Stage Malaria Infection After Direct Venous Inoculation of Cryopreserved P. Falciparum (NF54 Strain) Sporozoites (PfSPZ-DVI) in Malaria naïve Healthy Adult Volunteers	Recruiting	NCT04310085	Phase 1	Artemether-Lumefantrine 20 Mg-120 Mg Oral Tablet
5	Survey of Intestinal Protozoal Infections and Sexual Transmitted Diseases Among Targeted Cohorts	Completed	NCT00630162
6	PCR in Blood Cultures of Individuals With Positive and Inconclusive Serology for Chagas' Disease	Completed	NCT00511589
7	Intestinal Helminths and Protozoan Infections in Patients With Colorectal Cancer: Prevalence and Possible Association With Cancer Pathogenesis	Active, not recruiting	NCT03173001
8	Effect on Pregnancy Outcomes, Infant Growth and Development of an Egg Intervention During Pregnancy in Indonesia	Not yet recruiting	NCT04694235

Search NIH Clinical Center for Parasitic Protozoa Infectious Disease

Inferred drug relations via UMLS ⁷¹ / NDF-RT ⁵¹ :

acetyl sulfisoxazole

Aminoglycoside Antimicrobial [EPC]

Antiprotozoal [EPC]

Ciprofloxacin

Dihydrofolate Reductase Inhibitor Antimicrobial [EPC]

Dihydrofolate Reductase Inhibitor Antiprotozoal [EPC]

Eflornithine

Eflornithine Hydrochloride

ERYTHROMYCIN PWDR

gemifloxacin mesylate

Macrolide Antimicrobial [EPC]

Metronidazole

Metronidazole Hydrochloride

METRONIDAZOLE PWDR

nitazoxanide

Nitroimidazole Antimicrobial [EPC]

Pentamidine

Pentamidine Isethionate

Polyene Antimicrobial [EPC]

Sulfisoxazole

Sulfisoxazole Diolamine

Sulfonamide Antimicrobial [EPC]

Tetracycline-class Antimicrobial [EPC]

Tinidazole

Cochrane evidence based reviews: protozoan infections

Sources

Genetic Tests for Parasitic Protozoa Infectious Disease

Sources

Anatomical Context for Parasitic Protozoa Infectious Disease

MalaCards organs/tissues related to Parasitic Protozoa Infectious Disease:

⁴⁰

Kidney, Small Intestine, Skin, Nk Cells, T Cells, Brain, Retina

Sources

Publications for Parasitic Protozoa Infectious Disease

Articles related to Parasitic Protozoa Infectious Disease:

(show top 50) (show all 608)

#	Title	Authors	PMID	Year
1	Socio-demographic influences on the prevalence of intestinal parasitic infections among workers in Qatar. ⁶¹	Younes N...Abu-Madi MA	33472686	2021
2	Detection and characterization of the Isospora lunaris infection from different finch hosts in southern Iran. ⁶¹	Rakhshandehroo E...Asadpour M	33179153	2021
3	The Stem Cell Revolution Revealing Protozoan Parasites' Secrets and Paving the Way towards Vaccine Development. ⁶¹	Pance A	33572549	2021
4	Diagnosis of intestinal protozoan infections in patients in Cuba by microscopy and molecular methods: advantages and disadvantages. ⁶¹	Jerez Puebla LE...Robertson LJ	33188802	2020
5	Protozoan infections are under-recognized in Swedish patients with gastrointestinal symptoms. ⁶¹	Ogren J...Matussek A	32638222	2020
6	Host-parasite interactions in vector-borne protozoan infections. ⁶¹	Baneth G...Olivieri A	33147559	2020
7	Global prevalence of intestinal parasitic infections and associated risk factors in pregnant women: a systematic review and meta-analysis. ⁶¹	Taghipour A...Ghaffarifar F	33007067	2020
8	Detection of Intravascular Hemolysis in Newborn Infants Using Urinary Carbonic Anhydrase I Immunoreactivity. ⁶¹	Hulikova A...Swietach P	32529247	2020
9	Discovery of Amphamide, a Drug Candidate for the Second Generation of Polyene Antibiotics. ⁶¹	Tevyashova AN...Shchekotikhin AE	32598131	2020
10	Gastrointestinal parasites of dromedary camel (Camelus dromedarius) in Algeria. ⁶¹	Bouragba M...Hakem A	33061238	2020
11	Targeting histone acetylation/deacetylation in parasites: an update (2017-2020). ⁶¹	Fioravanti R...Mai A	32615359	2020
12	Leishmania Immunity: Advancing Immunotherapy and Vaccine Development. ⁶¹	Ikeogu NM...Uzonna JE	32784615	2020
13	Antimicrobial peptides in human corneal tissue of patients with fungal keratitis. ⁶¹	Mohammed I...Mittal R	32855162	2020
14	Alkyl and Aryl Derivatives Based on p-Coumaric Acid Modification and Inhibitory Action against Leishmania braziliensis and Plasmodium falciparum. ⁶¹	Lopes SP...de Sousa DP	32664596	2020
15	Heme oxygenase-1 in protozoan infections: A tale of resistance and disease tolerance. ⁶¹	Silva RCMC...Bozza MT	32692767	2020
16	Bacterial and protozoan pathogens/symbionts in ticks infecting wild grasscutters (Thryonomys swinderianus) in Ghana. ⁶¹	Adenyo C...Nakao R	32035054	2020
17	Interleukin-17 mediated immunity during infections with Trypanosoma cruzi and other protozoans. ⁶¹	Amezcua Vesely MC...Acosta Rodriguez EV	31987839	2020
18	Intestinal Protozoan Parasitic Infections in Immunocompromised Child Patients with Diarrhea. ⁶¹	Caner A...Turgay N	31875601	2020
19	Molecular prevalence of intestinal parasites infections in children with diarrhea in Franceville, Southeast of Gabon. ⁶¹	Oyegue-Liabagui SL...Lekana-Douki JB	32414337	2020
20	Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018. ⁶¹	Bauhofer AFL...de Deus N	32320399	2020
21	Clearing or subverting the enemy: Role of autophagy in protozoan infections. ⁶¹	Ghartey-Kwansah G...Abu EK	32088215	2020
22	Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis. ⁶¹	Lauwaet T...Eckmann L	32302296	2020
23	Microglia in neuropathology caused by protozoan parasites. ⁶¹	Figarella K...Duszenko M	31682077	2020
24	Prevalence of Intestinal Parasitic Infections among the Bulgarian Population Over a Three Year Period (2015 - 2017). ⁶¹	Harizanov R...Videnova M	32063735	2020
25	Medication for COVID-19-an Overview of Approaches Currently Under Study. ⁶¹	Stahlmann R...Lode H	32343658	2020
26	The zebrafish as a model for gastrointestinal tract-microbe interactions. ⁶¹	Flores EM...Krachler AM	31872937	2020
27	Targeting Parasite-Produced Macrophage Migration Inhibitory Factor as an Antivirulence Strategy With Antibiotic-Antibody Combination to Reduce Tissue Damage. ⁶¹	Ghosh S...Moonah S	31677380	2020
28	Mitochondrially-targeted treatment strategies. ⁶¹	Bozi LHM...Ferreira JCB	31866004	2020
29	Organoids - New Models for Host-Helminth Interactions. ⁶¹	Duque-Correa MA...Berriman M	31791691	2020
30	Changes in the epidemiological profile of intestinal parasites after a school-based large-scale treatment for soil-transmitted helminths in a community in northeastern Brazil: Epidemiological profile after large-scale school-based treatment for STH. ⁶¹	Oliveira YLDC...Dolabella SS	31758913	2020
31	Update on the major imported protozoan infections in travelers and migrants. ⁶¹	Norman FF...Lopez-Velez R	32065535	2020
32	The Delay in the Licensing of Protozoal Vaccines: A Comparative History. ⁶¹	Palatnik-de-Sousa CB...Nico D	32210953	2020
33	Old Antiprotozoal Drugs: Are They Still Viable Options for Parasitic Infections or New Options for Other Diseases? ⁶¹	Cortez-Maya S...Rivera G	31264538	2020
34	Assessment of Prevalence and Risk Factors for Intestinal Parasitosis, Malnutrition, and Anemia among School Children in Ghindae Area, Eritrea. ⁶¹	Kesete Y...Seltene B	33178289	2020
35	First evidences of salt and pepper retinal lesions in patients with intestinal protozoan infections in Iran. ⁶¹	Jafari R...Fakhar M	31903888	2020
36	More Than Half Prevalence of Protozoan Parasitic Infections Among Diarrheic Outpatients in Eastern Tigrai, Ethiopia, 2019; A Cross-Sectional Study. ⁶¹	Berhe B...Negash H	32021317	2020
37	Prevalence and associated risk factors of human intestinal parasitic infections: a population-based study in the southeast of Kerman province, southeastern Iran. ⁶¹	Abbaszadeh Afshar MJ...Samimi M	31906872	2020
38	Prevalence of Intestinal Parasitic Infections and Associated Water, Sanitation, and Hygiene Risk Factors among School Children in Mwea Irrigation Scheme, Kirinyaga County, Kenya. ⁶¹	Njambi E...Njenga SM	32454837	2020
39	Gastrointestinal parasites in shelter cats of central Italy. ⁶¹	Sauda F...Perrucci S	31796183	2019
40	Intestinal parasite infections and associated factors among inmates of Arba Minch prison, southern Ethiopia: cross sectional study. ⁶¹	Ameya G...Eshetu M	31888496	2019
41	Correlates of parasites and pseudoparasites in wolves (Canis lupus) across continents: A comparison among Yellowstone (USA), Abruzzo (IT) and Mercantour (FR) national parks. ⁶¹	Molnar B...Betschart B	31667082	2019
42	Prevalence of selected intestinal protozoan infections in marginalized rural communities in Palestine. ⁶¹	Al-Jawabreh A...Nasereddin A	31829156	2019
43	Reduced prevalence of soil-transmitted helminths and high frequency of protozoan infections in the surrounding urban area of Curitiba, Paraná, Brazil. ⁶¹	Oishi CY...Munoz-Antoli C	31660444	2019
44	Gastrointestinal parasites as a possible threat to an endangered autochthonous Portuguese sheep breed. ⁶¹	Ruano ZM...Mateus TL	31679528	2019
45	Unlocking the genetic basis of monarch butterflies' use of medicinal plants. ⁶¹	Smilanich AM...Nuss AB	31713935	2019
46	Validation of Human Sterol 14α-Demethylase (CYP51) Druggability: Structure-Guided Design, Synthesis, and Evaluation of Stoichiometric, Functionally Irreversible Inhibitors. ⁶¹	Friggeri L...Lepesheva GI	31663733	2019
47	Prevalence of intestinal parasitic infections in Hawassa University students' clinic, Southern Ethiopia: a 10-year retrospective study. ⁶¹	Menjetta T...Asnake S	31661021	2019
48	Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules. ⁶¹	Malik A...Tomar S	31199070	2019
49	A prevalence survey of enteral parasites in preschool children in the Mangochi District of Malawi. ⁶¹	Jones TPW...Bailey RL	31604429	2019
50	Variable Surface Glycoprotein from Trypanosoma brucei Undergoes Cleavage by Matrix Metalloproteinases: An in silico Approach. ⁶¹	Moreno CJG...Silva MS	31597256	2019

Sources

Genes for Parasitic Protozoa Infectious Disease

Genes related to Parasitic Protozoa Infectious Disease (0 elite genes):

(show top 50) (show all 69)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	H2AC18	H2A Clustered Histone 18	Protein Coding	12.37	DISEASES inferred ¹⁵ ¹⁵
2	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	11.25	DISEASES inferred ¹⁵ ¹⁵
3	ICOSLG	Inducible T Cell Costimulator Ligand	Protein Coding	11.01	DISEASES inferred ¹⁵ ¹⁵
4	SERPINA3	Serpin Family A Member 3	Protein Coding	9.91	DISEASES inferred ¹⁵ ¹⁵
5	EPRS1	Glutamyl-Prolyl-TRNA Synthetase 1	Protein Coding	9.45	DISEASES inferred ¹⁵ ¹⁵
6	CD4	CD4 Molecule	Protein Coding	9.38	DISEASES inferred ¹⁵
7	CD8A	CD8a Molecule	Protein Coding	9.05	DISEASES inferred ¹⁵
8	IL10	Interleukin 10	Protein Coding	9.03	DISEASES inferred ¹⁵
9	MT-CYB	Mitochondrially Encoded Cytochrome B	Protein Coding	8.82	DISEASES inferred ¹⁵
10	TNF	Tumor Necrosis Factor	Protein Coding	8.75	DISEASES inferred ¹⁵
11	AKR1C2	Aldo-Keto Reductase Family 1 Member C2	Protein Coding	8.75	DISEASES inferred ¹⁵
12	IL4	Interleukin 4	Protein Coding	8.64	DISEASES inferred ¹⁵
13	LMLN	Leishmanolysin Like Peptidase	Protein Coding	8.57	DISEASES inferred ¹⁵
14	SIGLEC5	Sialic Acid Binding Ig Like Lectin 5	Protein Coding	8.49	DISEASES inferred ¹⁵ ¹⁵
15	IL2	Interleukin 2	Protein Coding	8.23	DISEASES inferred ¹⁵
16	PRODH	Proline Dehydrogenase 1	Protein Coding	8.21	DISEASES inferred ¹⁵ ¹⁵
17	IL6	Interleukin 6	Protein Coding	8.19	DISEASES inferred ¹⁵
18	ALB	Albumin	Protein Coding	8.11	DISEASES inferred ¹⁵
19	DHFR	Dihydrofolate Reductase	Protein Coding	8.1	DISEASES inferred ¹⁵
20	ACKR1	Atypical Chemokine Receptor 1 (Duffy Blood Group)	Protein Coding	8.05	DISEASES inferred ¹⁵
21	G6PD	Glucose-6-Phosphate Dehydrogenase	Protein Coding	7.96	DISEASES inferred ¹⁵
22	IL1B	Interleukin 1 Beta	Protein Coding	7.94	DISEASES inferred ¹⁵
23	IFNG	Interferon Gamma	Protein Coding	7.94	DISEASES inferred ¹⁵
24	TLR4	Toll Like Receptor 4	Protein Coding	7.9	DISEASES inferred ¹⁵
25	TLR9	Toll Like Receptor 9	Protein Coding	7.89	DISEASES inferred ¹⁵
26	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	7.86	DISEASES inferred ¹⁵
27	TLR2	Toll Like Receptor 2	Protein Coding	7.83	DISEASES inferred ¹⁵
28	APOL1	Apolipoprotein L1	Protein Coding	7.71	DISEASES inferred ¹⁵
29	IL17A	Interleukin 17A	Protein Coding	7.71	DISEASES inferred ¹⁵
30	HSPA4	Heat Shock Protein Family A (Hsp70) Member 4	Protein Coding	7.71	DISEASES inferred ¹⁵
31	MT-CO1	Mitochondrially Encoded Cytochrome C Oxidase I	Protein Coding	7.63	DISEASES inferred ¹⁵
32	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	7.53	DISEASES inferred ¹⁵
33	CRP	C-Reactive Protein	Protein Coding	7.52	DISEASES inferred ¹⁵
34	IL5	Interleukin 5	Protein Coding	7.51	DISEASES inferred ¹⁵
35	IL13	Interleukin 13	Protein Coding	7.5	DISEASES inferred ¹⁵
36	MYD88	MYD88 Innate Immune Signal Transduction Adaptor	Protein Coding	7.48	DISEASES inferred ¹⁵
37	CXCL10	C-X-C Motif Chemokine Ligand 10	Protein Coding	7.48	DISEASES inferred ¹⁵
38	GYPA	Glycophorin A (MNS Blood Group)	Protein Coding	7.46	DISEASES inferred ¹⁵
39	CCR5	C-C Motif Chemokine Receptor 5	Protein Coding	7.46	DISEASES inferred ¹⁵
40	MIR27A	MicroRNA 27a	RNA Gene	7.45	DISEASES inferred ¹⁵ ¹⁵
41	ITGAX	Integrin Subunit Alpha X	Protein Coding	7.44	DISEASES inferred ¹⁵
42	KDR	Kinase Insert Domain Receptor	Protein Coding	7.42	DISEASES inferred ¹⁵
43	HP	Haptoglobin	Protein Coding	7.39	DISEASES inferred ¹⁵
44	PRF1	Perforin 1	Protein Coding	7.39	DISEASES inferred ¹⁵
45	PROCR	Protein C Receptor	Protein Coding	7.38	DISEASES inferred ¹⁵
46	FOXP3	Forkhead Box P3	Protein Coding	7.36	DISEASES inferred ¹⁵
47	CD40	CD40 Molecule	Protein Coding	7.36	DISEASES inferred ¹⁵
48	CFHR2	Complement Factor H Related 2	Protein Coding	7.35	DISEASES inferred ¹⁵ ¹⁵
49	CSF2	Colony Stimulating Factor 2	Protein Coding	7.34	DISEASES inferred ¹⁵
50	TPI1	Triosephosphate Isomerase 1	Protein Coding	7.28	DISEASES inferred ¹⁵

Sources

Variations for Parasitic Protozoa Infectious Disease

Sources

Expression for Parasitic Protozoa Infectious Disease

Search GEO for disease gene expression data for Parasitic Protozoa Infectious Disease.

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Pathways for Parasitic Protozoa Infectious Disease

Pathways related to Parasitic Protozoa Infectious Disease according to GeneCards Suite gene sharing:

(show all 38)

#	Super pathways	Score	Top Affiliating Genes
1	PAK Pathway ⁶³ Show member pathways Antioxidant Action of Vitamin-C ⁶³ Epithelial Adherens Junctions ⁶³	13.27	TNF IL6 IL4 IL2 IL10 CD4
2	Allograft rejection ³⁶ ¹ Show member pathways Antigen processing and presentation ³⁶ Asthma ³⁶ Autoimmune thyroid disease ³⁶ CTL Mediated Apoptosis ⁶³ Graft-versus-host disease ³⁶ Intestinal immune network for IgA production ³⁶ THC Differentiation Pathway ⁶³ Type I diabetes mellitus ³⁶ Viral myocarditis ³⁶	12.78	TNF IL6 IL4 IL2 IL10 ICOSLG
3	Immune response NFAT in immune response ²³ Show member pathways Immune response CD28 signaling ²³ Immune response ICOS pathway in T-helper cell ²³ Immune response T cell receptor signaling pathway ²³	12.6	TNF IL4 IL2 IL10 ICOSLG CD4
4	Immune response IL-23 signaling pathway ²³ Show member pathways Angiopoietin receptor Tie2-mediated signaling ¹ Angiopoietin-TIE2 Signaling ⁶³ Development Angiopoietin - Tie2 signaling ²³ Development PDGF signaling via STATs and NF-kB ²³ IL23-mediated signaling events ¹ Immune response IL-10 signaling pathway ²³ Rac1/Pak1/p38/MMP-2 pathway ¹	12.57	TNF IL6 IL2 IL10 CD4
5	Th17 cell differentiation ³⁶ Show member pathways IL-22 Pathway ⁶³ Immune response IL-22 signaling pathway ²³ Inflammatory bowel disease ³⁶ Th1 and Th2 cell differentiation ³⁶	12.57	TNF IL6 IL4 IL2 IL10 CD4
6	T cell receptor signaling pathway ³⁶ Show member pathways PD-L1 expression and PD-1 checkpoint pathway in cancer ³⁶ T-Cell antigen Receptor (TCR) Signaling Pathway ¹ T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection ¹	12.56	TNF IL6 IL4 IL2 IL10 CD8A
7	NF-kappaB Signaling ⁴	12.55	TNF IL4 IL2 IL10 CD8A
8	Human T-cell leukemia virus 1 infection ³⁶	12.31	TNF IL6 IL2 CD4
9	Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions ⁶⁴ Show member pathways Chemokine receptors bind chemokines ⁶⁵ Viral protein interaction with cytokine and cytokine receptor ³⁶	12.31	TNF IL6 IL2 IL10 CCR6 ACKR1
10	Immune response IFN alpha/beta signaling pathway ²³ Show member pathways Cytokine Network ⁶³ Interferon alpha/beta signaling ⁶⁵ Regulation of IFNA signaling ⁶⁵	12.25	TNF IL6 IL4 IL2 IL10
11	Folate Metabolism ¹ Show member pathways Selenium Micronutrient Network ¹ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	12.24	TNF SERPINA3 IL6 IL4 IL2 DHFR
12	C-type lectin receptor signaling pathway ³⁶ Show member pathways Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways ⁶⁴	12.19	TNF IL6 IL2 IL10
13	Yersinia infection ³⁶	12.02	TNF IL6 IL2 IL10 CD8A CD4
14	Spinal Cord Injury ¹	11.99	TNF IL6 IL4 IL2
15	Interleukin-4 and 13 signaling ⁶⁵	11.95	TNF IL6 IL4 IL10
16	IL12-mediated signaling events ¹ Show member pathways Immune response IL-12-induced IFN-gamma production ²³	11.94	IL4 IL2 CD8A CD4
17	Hematopoietic cell lineage ³⁶	11.9	TNF IL6 IL4 CD8A CD4
18	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.76	TNF IL6 IL4 IL2 IL10 CD8A
19	Th1 Differentiation Pathway ⁶⁴ Show member pathways IL27-mediated signaling events ¹	11.74	TNF IL6 IL2 IL10 CD4
20	Pertussis ³⁶	11.73	TNF IL6 IL10
21	Calcineurin-regulated NFAT-dependent transcription in lymphocytes ¹ Show member pathways Calcium signaling in the CD4+ TCR pathway ¹	11.73	TNF IL4 IL2
22	Dendritic Cells Developmental Lineage Pathway ⁶⁴	11.67	TNF IL6 IL2 IL10 CD8A CD4
23	Photodynamic therapy-induced NF-kB survival signaling ¹ Show member pathways Immune response MIF-mediated glucocorticoid regulation ²³	11.64	TNF IL6 IL2
24	Lung fibrosis ¹	11.64	TNF IL6 IL4
25	Downstream signaling in naive CD8+ T cells ¹ Show member pathways Ras signaling in the CD4+ TCR pathway ¹	11.62	TNF IL2 CD8A
26	Malaria ³⁶	11.55	TNF IL6 IL10 ACKR1
27	IgA-Producing B Cells in the Intestine ⁶⁴	11.55	TNF IL6 IL4 IL10 ICOSLG CCR6
28	Photodynamic therapy-induced AP-1 survival signaling. ¹	11.53	TNF IL6 IL2
29	Interleukin-10 signaling ⁶⁵	11.53	TNF IL6 IL4 IL10
30	Th2 Differentiation Pathway ⁶⁴	11.49	IL4 IL2 IL10 CD4
31	Innate Lymphoid Cell Differentiation Pathways ⁶⁴	11.4	TNF IL4 IL2 IL10 CD8A CD4
32	African trypanosomiasis ³⁶	11.37	TNF IL6 IL10
33	IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types ⁶⁴ Show member pathways IL-2 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types ⁶⁴	11.36	TNF IL2 IL10
34	IL-10 Pathway ⁶³	11.34	TNF IL6 IL10
35	Development and heterogeneity of the ILC family ¹	11.29	TNF IL6 IL4
36	Antifolate resistance ³⁶	11.27	TNF IL6 DHFR
37	OX40 Pathway ⁶³	11.17	IL4 IL2 IL10
38	Cytokines and Inflammatory Response ¹	10.56	TNF IL6 IL4 IL2 IL10 CD4

Sources

GO Terms for Parasitic Protozoa Infectious Disease

Cellular components related to Parasitic Protozoa Infectious Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:0009897	9.02	TNF ICOSLG CD8A CD4 CCR6

Biological processes related to Parasitic Protozoa Infectious Disease according to GeneCards Suite gene sharing:

(show all 19)

#	Name	GO ID	Score	Top Affiliating Genes
1	response to glucocorticoid	GO:0051384	9.73	TNF IL6 IL10
2	humoral immune response	GO:0006959	9.7	TNF IL6 CCR6
3	cytokine-mediated signaling pathway	GO:0019221	9.63	TNF IL6 IL4 IL2 IL10 CD4
4	positive regulation of tyrosine phosphorylation of STAT protein	GO:0042531	9.62	TNF IL6 IL4 IL2
5	negative regulation of T-helper 17 cell differentiation	GO:2000320	9.58	IL4 IL2
6	positive regulation of isotype switching to IgG isotypes	GO:0048304	9.58	IL4 IL2
7	positive regulation of JAK-STAT cascade	GO:0046427	9.58	TNF IL6 IL10
8	negative regulation of lipid storage	GO:0010888	9.57	TNF IL6
9	positive regulation of T cell proliferation	GO:0042102	9.56	IL6 IL4 IL2 CD4
10	endothelial cell apoptotic process	GO:0072577	9.55	TNF IL10
11	vascular endothelial growth factor production	GO:0010573	9.54	TNF IL6
12	positive regulation of immunoglobulin production	GO:0002639	9.54	IL6 IL2 IL10
13	positive regulation of mononuclear cell migration	GO:0071677	9.51	TNF IL4
14	negative regulation of cytokine production involved in immune response	GO:0002719	9.49	TNF IL10
15	type 2 immune response	GO:0042092	9.48	IL4 IL10
16	positive regulation of plasma cell differentiation	GO:1900100	9.46	IL2 IL10
17	regulation of isotype switching	GO:0045191	9.43	IL4 IL10
18	T cell activation	GO:0042110	9.26	IL4 ICOSLG CD8A CD4
19	immune response	GO:0006955	9.23	TNF IL6 IL4 IL2 IL10 CD8A

Molecular functions related to Parasitic Protozoa Infectious Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	growth factor activity	GO:0008083	9.26	IL6 IL4 IL2 IL10
2	cytokine activity	GO:0005125	9.02	TNF IL6 IL4 IL2 IL10

Sources

Sources for Parasitic Protozoa Infectious Disease

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Mar-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia

Parasitic Protozoa Infectious Disease

Aliases & Classifications for Parasitic Protozoa Infectious Disease

MalaCards integrated aliases for Parasitic Protozoa Infectious Disease:

Classifications:

External Ids:

Summaries for Parasitic Protozoa Infectious Disease

Related Diseases for Parasitic Protozoa Infectious Disease

Diseases related to Parasitic Protozoa Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Parasitic Protozoa Infectious Disease:

Symptoms & Phenotypes for Parasitic Protozoa Infectious Disease

MGI Mouse Phenotypes related to Parasitic Protozoa Infectious Disease:

Drugs & Therapeutics for Parasitic Protozoa Infectious Disease

Drugs for Parasitic Protozoa Infectious Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 71 / NDF-RT 51 :

Cochrane evidence based reviews: protozoan infections

Genetic Tests for Parasitic Protozoa Infectious Disease

Anatomical Context for Parasitic Protozoa Infectious Disease

MalaCards organs/tissues related to Parasitic Protozoa Infectious Disease:

Publications for Parasitic Protozoa Infectious Disease

Articles related to Parasitic Protozoa Infectious Disease:

Genes for Parasitic Protozoa Infectious Disease

Genes related to Parasitic Protozoa Infectious Disease (0 elite genes):

Variations for Parasitic Protozoa Infectious Disease

Expression for Parasitic Protozoa Infectious Disease

Pathways for Parasitic Protozoa Infectious Disease

Pathways related to Parasitic Protozoa Infectious Disease according to GeneCards Suite gene sharing:

GO Terms for Parasitic Protozoa Infectious Disease

Cellular components related to Parasitic Protozoa Infectious Disease according to GeneCards Suite gene sharing:

Biological processes related to Parasitic Protozoa Infectious Disease according to GeneCards Suite gene sharing:

Molecular functions related to Parasitic Protozoa Infectious Disease according to GeneCards Suite gene sharing:

Sources for Parasitic Protozoa Infectious Disease

Inferred drug relations via UMLS ⁷¹ / NDF-RT ⁵¹ :