MCID: PRT028
MIFTS: 24

Paratesticular Lipoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Paratesticular Lipoma

MalaCards integrated aliases for Paratesticular Lipoma:

Name: Paratesticular Lipoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:10207
NCIt 50 C6384
UMLS 71 C1335348

Summaries for Paratesticular Lipoma

Disease Ontology : 12 A reproductive organ benign neoplasm that derives from fat cells located in the paratesticular region.

MalaCards based summary : Paratesticular Lipoma is related to pleomorphic lipoma and lipomatosis, multiple. An important gene associated with Paratesticular Lipoma is ANO1 (Anoctamin 1), and among its related pathways/superpathways are Integrated Cancer Pathway and DNA damage_ATM/ATR regulation of G1/S checkpoint. Affiliated tissues include paratesticular region, and related phenotypes are craniofacial and liver/biliary system

Related Diseases for Paratesticular Lipoma

Diseases related to Paratesticular Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 197)
# Related Disease Score Top Affiliating Genes
1 pleomorphic lipoma 30.5 MDM2 CDK4
2 lipomatosis, multiple 30.3 MDM2 CDK4 ANO1
3 lipoma of spermatic cord 29.2 MDM2 KRT19 ENO2 CEACAM5 CDK4 ANO1
4 ring chromosome 7 10.2 MDM2 CDK4
5 ring chromosome 10.2 MDM2 CDK4
6 mediastinum liposarcoma 10.2 MDM2 CDK4
7 colon leiomyosarcoma 10.2 CEACAM5 ANO1
8 infiltrating lipoma 10.2 MDM2 CDK4
9 spindle cell liposarcoma 10.2 MDM2 CDK4
10 pediatric liposarcoma 10.2 MDM2 CDK4
11 undifferentiated embryonal sarcoma of the liver 10.2 MDM2 CDK4
12 embryonal sarcoma 10.2 MDM2 CDK4
13 diffuse lipomatosis 10.2 MDM2 CDK4
14 lipoblastoma 10.2 MDM2 CDK4
15 malignant inflammatory fibrous histiocytoma 10.2 MDM2 CDK4
16 liposarcoma of bone 10.2 MDM2 CDK4
17 liver lipoma 10.2 CEACAM5 AFP
18 adult liposarcoma 10.2 MDM2 CDK4
19 gestational ovarian choriocarcinoma 10.2 CEACAM5 AFP
20 immature teratoma of ovary 10.2 CEACAM5 AFP
21 urachal adenocarcinoma 10.2 CEACAM5 AFP
22 liver inflammatory pseudotumor 10.2 CEACAM5 AFP
23 rectum signet ring adenocarcinoma 10.2 CEACAM5 AFP
24 mixed liposarcoma 10.2 MDM2 CDK4
25 gallbladder leiomyosarcoma 10.2 KRT19 AFP
26 adult teratoma 10.2 CEACAM5 AFP
27 hereditary melanoma 10.2 MDM2 CDK4
28 dermoid cyst of ovary 10.2 CEACAM5 AFP
29 infiltrating angiolipoma 10.2 MDM2 CDK4
30 bile duct cystadenocarcinoma 10.2 CEACAM5 AFP
31 peripheral osteosarcoma 10.2 MDM2 CDK4
32 juxtacortical osteosarcoma 10.2 MDM2 CDK4
33 colonic lymphangioma 10.2 CEACAM5 AFP
34 spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2 10.2 AFP ACTA1
35 extraosseous osteosarcoma 10.2 MDM2 CDK4
36 ovarian mixed germ cell neoplasm 10.2 CEACAM5 AFP
37 spindle cell lipoma 10.2 MDM2 CDK4
38 sclerosing hepatic carcinoma 10.2 KRT19 AFP
39 liver sarcoma 10.1 CEACAM5 AFP
40 ovarian germ cell teratoma 10.1 KRT19 AFP
41 myositis ossificans 10.1 MDM2 CDK4
42 jejunal neoplasm 10.1 ENO2 ANO1
43 acinar cell carcinoma 10.1 ANO1 AFP
44 pancreatic acinar cell adenocarcinoma 10.1 KRT19 AFP
45 cellular myxoid liposarcoma 10.1 MDM2 CDK4
46 plexiform schwannoma 10.1 ENO2 ANO1
47 ischemic fasciitis 10.1 MDM2 CDK4
48 gastric hemangioma 10.1 ENO2 ANO1
49 common bile duct disease 10.1 CEACAM5 AFP
50 abdominal tuberculosis 10.1 CEACAM5 AFP

Graphical network of the top 20 diseases related to Paratesticular Lipoma:



Diseases related to Paratesticular Lipoma

Symptoms & Phenotypes for Paratesticular Lipoma

MGI Mouse Phenotypes related to Paratesticular Lipoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.72 ACTA1 CDK4 ENO2 KRT19 MDM2
2 liver/biliary system MP:0005370 9.65 ACTA1 AFP CDK4 KRT19 MDM2
3 neoplasm MP:0002006 9.55 AFP ALK CDK4 KRT19 MDM2
4 reproductive system MP:0005389 9.43 ACTA1 AFP ALK CDK4 KRT19 MDM2
5 skeleton MP:0005390 9.1 ACTA1 ALK ANO1 CDK4 KRT19 MDM2

Drugs & Therapeutics for Paratesticular Lipoma

Search Clinical Trials , NIH Clinical Center for Paratesticular Lipoma

Genetic Tests for Paratesticular Lipoma

Anatomical Context for Paratesticular Lipoma

The Foundational Model of Anatomy Ontology organs/tissues related to Paratesticular Lipoma:

19
Paratesticular Region

Publications for Paratesticular Lipoma

Articles related to Paratesticular Lipoma:

# Title Authors PMID Year
1
[Paratesticular lipoma]. 61
11103506 2000
2
[Paratesticular lipoma]. 61
9412198 1997
3
Unusual, benign asymptomatic scrotal masses in children: case reports and review of the literature. 61
7860206 1994
4
Paratesticular lipoma. 61
5911777 1966

Variations for Paratesticular Lipoma

Expression for Paratesticular Lipoma

Search GEO for disease gene expression data for Paratesticular Lipoma.

Pathways for Paratesticular Lipoma

Pathways related to Paratesticular Lipoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.82 MDM2 CDK4
2 10.6 MDM2 CDK4
3 10.13 MDM2 CDK4

GO Terms for Paratesticular Lipoma

Cellular components related to Paratesticular Lipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.1 KRT19 ENO2 CEACAM5 ANO1 ALK ACTA1

Biological processes related to Paratesticular Lipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell cycle GO:0045787 9.16 MDM2 CDK4
2 response to steroid hormone GO:0048545 8.96 MDM2 ACTA1
3 negative regulation of cell cycle arrest GO:0071157 8.62 MDM2 CDK4

Sources for Paratesticular Lipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....