Paratyphoid Fever disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: PRT002 MIFTS: 55	Paratyphoid Fever Categories: Gastrointestinal diseases, Infectious diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Paratyphoid Fever

MalaCards integrated aliases for Paratyphoid Fever:

Name: Paratyphoid Fever ¹² ⁷⁴ ⁵⁸ ⁴³ ¹⁵ ¹⁷ ⁷¹

Paratyphoid B Fever ¹² ⁷¹

Paratyphoid C Fever ¹² ⁷¹

Paratyphoid Fever a ¹² ³²

Paratyphoid Fever B ¹² ³²

Paratyphoid Fever C ¹² ³²

Paratyphoid a Fever ¹²

Paratyphoid a ¹²

Paratyphoid B ¹²

Paratyphoid C ¹²

Paratyphoid ¹²

Characteristics:

Orphanet epidemiological data:

⁵⁸

paratyphoid fever
Inheritance: Not applicable;

Classifications:

MalaCards categories:
Global: Infectious diseases Rare diseases
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

ICD10: ³² ³³

Certain infectious and parasitic diseases

Intestinal infectious diseases

Typhoid and paratyphoid fevers

Paratyphoid fever A

Paratyphoid fever B

Paratyphoid fever C

Paratyphoid fever, unspecified

Orphanet: ⁵⁸

Rare infectious diseases

External Ids:

Disease Ontology ¹² DOID:3055

ICD9CM ³⁴ 002.1 002.2 002.3 more

MeSH ⁴³ D010284

NCIt ⁴⁹ C34894 C34895 C34896 more

SNOMED-CT ⁶⁷ 51254007 71085009 76623002 more

ICD10 ³² A01.1 A01.2 A01.3 more

ICD10 via Orphanet ³³ A01.1 A01.2 A01.3 more

UMLS via Orphanet ⁷² C0030528

Orphanet ⁵⁸ ORPHA443227

EFO ¹⁷ EFO_0007420

UMLS ⁷¹ C0030528 C0343375 C0343376 more

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Summaries for Paratyphoid Fever

Disease Ontology : ¹² A primary bacterial infectious disease that results in infection located in intestine, has material basis in Salmonella enterica subsp enterica serovar Paratyphi A, B or C, which are transmitted by ingestion of contaminated food. The infection has symptom fever, has symptom headache, has symptom abdominal pain, has symptom malaise, has symptom anorexia, has symptom constipation, has symptom rosy spots on the central body, has symptom non productive cough (in early stage of illness), has symptom bradycardia, and has symptom hepatosplenomegaly.

MalaCards based summary : Paratyphoid Fever, also known as paratyphoid b fever, is related to salmonellosis and tetanus, and has symptoms including constipation, fever and abdominal pain. An important gene associated with Paratyphoid Fever is PRKN (Parkin RBR E3 Ubiquitin Protein Ligase), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Vaccines and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include intestine, skin and liver, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : ⁷⁴ Paratyphoid fever, also known simply as paratyphoid, is a bacterial infection caused by one of the three... more...

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Related Diseases for Paratyphoid Fever

Diseases related to Paratyphoid Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 346)

#	Related Disease	Score	Top Affiliating Genes
1	salmonellosis	31.3	TNF SPI1 SLC11A1 IL1B IFNGR1 IFNG
2	tetanus	30.6	TNF IL1B IFNG CRP
3	meningitis	30.6	TNF IL1B IFNG CRP
4	schistosomiasis	30.6	TNF IL1A IFNGR1 IFNG
5	spondylitis	30.6	TNF IFNG CRP
6	dysentery	30.5	TNF IL1B IL1A CRP
7	stomatitis	30.5	TNF IL1B IFNG
8	aortitis	30.4	TNF CRP
9	prostatitis	30.3	TNF IL1B IL1A
10	typhoid fever	30.3	TNFRSF1A TNF SPI1 SLC11A1 IL1R1 IL1B
11	brucellosis	30.3	TNF SLC11A1 IFNG CRP
12	peritonitis	30.2	TNF IL1B IFNG CRP
13	leptospirosis	30.2	TNF IL1B IFNG CRP
14	appendicitis	30.2	TNF IL1B IFNG CRP
15	gastroenteritis	30.2	TNF IL1B IFNG CRP
16	aphthous stomatitis	30.1	TNF IL1B IL1A IFNG
17	bronchitis	30.1	TNF IL1B CRP
18	pyelonephritis	30.0	TNF IL1B IFNG CRP
19	pneumonia	30.0	TNF IL1B IFNG CRP
20	colitis	30.0	TNF IL1R1 IL1B IFNG
21	viral hepatitis	30.0	TNFRSF1A TNF IFNG CRP
22	toxic shock syndrome	29.9	TNF IL1R1 IL1B IFNG CRP
23	osteomyelitis	29.8	TNF IL1B IL1A IFNGR1 IFNG CASP1
24	bone inflammation disease	29.8	TNFRSF1A TNF IL1B IFNG CRP CASP1
25	leprosy 3	29.7	TNF SLC11A1 PRKN IL1B IFNG
26	osteoarthritis	29.6	TNF IL1R1 IL1B IL1A CRP
27	malaria	28.0	TNFRSF1A TNF IL1R1 IL1B IL1A IL12B
28	rare form of salmonellosis	10.9
29	drug reaction with eosinophilia and systemic symptoms	10.5	TNF CRP
30	interferon gamma, receptor 1, deficiency	10.5	IFNGR1 IFNG
31	polyarticular juvenile idiopathic arthritis	10.5	TNF IFNG
32	autoimmune myocarditis	10.5	TNF IFNG
33	axillary adenitis	10.5	IFNGR1 IFNG
34	spotted fever rickettsiosis	10.5	TNF IFNG
35	rheumatoid arthritis interstitial lung disease	10.5	TNF CRP
36	posterior scleritis	10.5	TNF CRP
37	chronic beryllium disease	10.5	TNF IFNG
38	cryopyrin-associated periodic syndrome	10.5	IL1R1 CRP
39	systemic onset juvenile idiopathic arthritis	10.5	TNF IL1B
40	pericardial tuberculosis	10.4	IFNG CRP
41	skeletal tuberculosis	10.4	IFNG CRP
42	palladium allergic contact dermatitis	10.4	TNF IL1B
43	kashin-beck disease	10.4	TNF IL1B
44	tuberculous peritonitis	10.4	IFNG CRP
45	louse-borne relapsing fever	10.4	TNF CRP
46	prosthetic joint infection	10.4	IL1B CRP
47	angelucci's syndrome	10.4	IL1B IFNG
48	neuroretinitis	10.4	IFNG CRP
49	renal infectious disease	10.4	CRP CASP1
50	soft tissue sarcoma	10.4	TNF IFNG

Graphical network of the top 20 diseases related to Paratyphoid Fever:

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Symptoms & Phenotypes for Paratyphoid Fever

Symptoms:

¹²

• constipation
• fever
• abdominal pain
• anorexia
• headache

• hepatosplenomegaly
• bradycardia
• malaise
• rosy spots on the central body
• non productive cough

GenomeRNAi Phenotypes related to Paratyphoid Fever according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-1	9.4	CASP1 IL1A IL1B PRKN TNF TNFRSF1A
2	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-2	9.4	CASP1 IL1A IL1B PRKN TNF TNFRSF1A

MGI Mouse Phenotypes related to Paratyphoid Fever:

⁴⁵ (show all 11)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	10.25	CASP1 CRP HGD IFNG IFNGR1 IL12B
2	cardiovascular system	MP:0005385	10.24	CASP1 CRP IFNG IFNGR1 IL1A IL1B
3	immune system	MP:0005387	10.21	CASP1 CRP HGD IFNG IFNGR1 IL12B
4	hematopoietic system	MP:0005397	10.17	CASP1 IFNG IFNGR1 IL12B IL1A IL1B
5	craniofacial	MP:0005382	10.02	IFNG IL12B IL1B IL1R1 SPI1 TNF
6	digestive/alimentary	MP:0005381	10	CASP1 IFNG IFNGR1 IL12B SLC11A1 TNF
7	integument	MP:0010771	9.97	CASP1 IFNG IFNGR1 IL1A IL1B IL1R1
8	mortality/aging	MP:0010768	9.93	CASP1 CLPX IFNG IFNGR1 IL12B IL1B
9	liver/biliary system	MP:0005370	9.8	HGD IFNG IFNGR1 IL1R1 SPI1 TNF
10	neoplasm	MP:0002006	9.7	CASP1 IFNG IFNGR1 IL12B IL1A IL1B
11	skeleton	MP:0005390	9.32	HGD IFNG IFNGR1 IL12B IL1B IL1R1

Sources

Drugs & Therapeutics for Paratyphoid Fever

Drugs for Paratyphoid Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Vaccines

Phase 4

Immunologic Factors

Phase 4

Azithromycin

Approved

Phase 3

83905-01-5

55185 447043

Synonyms:

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside

121470-24-4

1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*

75199_FLUKA

83905-01-5

9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A

AC-16014

AC1L9KEG

Aritromicina

Azadose

Azasite

Azenil

Azifast

Azigram

Azimakrol

Azithramycine

azithromycin

Azithromycin

Azithromycin & Tumor Necrosis Factor

Azithromycin (AIDS Initiative)

Azithromycin (anhydrous)

Azithromycin dihydrate

Azithromycin monohydrate

Azithromycin Monohydrate

Azithromycin pfizer brand

Azithromycine

Azithromycinum

Azitrocin

Azitromax

Azitromicina

Azitromin

Azythromycin

Bayer brand OF azithromycin dihydrate

BIDD:GT0792

Bio-0676

BRN 5387583

BSPBio_002285

C38H72N2O12

CCRIS 1961

CHEBI:2955

CHEMBL529

CID447043

CP62,993

CP-62993

CPD000471864

DCH3

Dihydrate, azithromycin

DivK1c_000233

DRG-0104

Funk brand OF azithromycin dihydrate

Goxal

Hemomycin

HMS1922G12

HMS2094M11

HMS500L15

HSDB 7205

IDI1_000233

KBio1_000233

KBio2_000787

KBio2_003355

KBio2_005923

KBio3_001505

KBioGR_000731

KBioSS_000787

Lesvi brand OF azithromycin dihydrate

LS-1834

Mack brand OF azithromycin dihydrate

Misultina

MLS001055353

MLS001066331

MLS001201763

MLS001304005

MLS001332499

MLS001332500

MolPort-002-507-426

Monohydrate, azithromycin

NCGC00090753-01

NCGC00090753-02

NINDS_000233

NSC643732

Pfizer brand OF azithromycin

Pfizer brand OF azithromycin dihydrate

Pharmacia brand OF azithromycin dihydrate

SAM002589961

SMR000471864

SPBio_001544

Spectrum_000307

SPECTRUM1503679

Spectrum2_001582

Spectrum3_000653

Spectrum4_000186

Spectrum5_001867

Sumamed

Toraseptol

Tromix

Ultreon

UNII-JTE4MNN1MD

Vinzam

Vita brand OF azithromycin dihydrate

XZ-450

Zentavion

ZIT

Zithromac

Zithromax

Zithromax IV

Zithromycin

Zitromax

Zitromax Avium 600

Zmas

Zmax

Z-Pak

Sulfamethoxazole

Approved

Phase 3

723-46-6

5329

Synonyms:

129378-89-8

3-(P-Aminobenzenesulfonamido)-5-methylisoxazole

3-(p-Aminophenylsulfonamido)-5-methylisoxazole

3-(P-Aminophenylsulfonamido)-5-methylisoxazole

3-(P-Aminophenylsulphonamido)-5-methylisoxazole

3-(para-Aminophenylsulphonamido)-5-methylisoxazole

3-(Para-aminophenylsulphonamido)-5-methylisoxazole

3-Sulfanilamido-5-methylisoxazole

3-Sulphanilamido-5-methylisoxazole

46850_RIEDEL

4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide

4-amino-N-(5-Methyl-1,2-oxazol-3-yl)benzenesulfonamide

4-amino-N-(5-Methyl-3-isoxazolyl)benzenesulfonamide

4-amino-N-(5-Methyl-3-isoxazolyl)-benzenesulfonamide

4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide

4-amino-N-(5-Methyl-3-isoxazolyl)benzenesulphonamide

4-amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide

4-Amino-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide

4-Amino-N-[5-methyl-3- isoxazolyl]benzenesulfonamide

5-Methyl-3-sulfanilamidoisoxazole

5-Methyl-3-sulfanylamidoisoxazole

5-Methyl-3-sulfonylamidoisoxazole

5-Methyl-3-sulphanil-amidoisoxazole

723-46-6

A047

AB00052099

AC-11118

AC1L1K42

AC1Q2J5R

AKOS000200952

ALBB-002089

Apo-Sulfamethoxazole

ARONIS018156

Azo Gantanol

azo-Gantanol

Azo-gantanol

Azo-Gantanol

Bactrim

Bactrimel

BAS 00836086

BB_SC-1251

BIDD:GT0731

BPBio1_000081

BRD-K28494619-001-05-0

BRN 0226453

BSPBio_000073

BSPBio_002028

C07315

C10H11N3O3S

CAS-723-46-6

CCRIS 567

CHEBI:9332

CHEMBL443

CID5329

CPD000058223

D00447

D013420

DB01015

DivK1c_000649

EINECS 211-963-3

Gamazole

Gantanol

Gantanol-DS

HMS1568D15

HMS1921A21

HMS2092K03

HMS502A11

HMS561O18

HSDB 3186

I01-0154

IDI1_000649

InChI=1/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

KBio1_000649

KBio2_001474

KBio2_004042

KBio2_006610

KBio3_001528

KBioGR_000749

KBioSS_001474

LS-1620

Maybridge1_007190

Metoxal

MLS000069732

MLS001055354

MLS001074165

MolPort-000-145-787

MS 53

N'-(5-methyl-3-isoxazole)sulfanilamide

N'-(5-Methyl-3-isoxazole)sulfanilamide

N'-(5-methyl-3-isoxazolyl)sulfanilamide

N'-(5-methyl-3-isoxazolyl)-sulfanilamide

N'-(5-Methyl-3-isoxazolyl)sulfanilamide

N'-(5-methylisoxazol-3-yl)sulphanilamide

N'-(5-Methylisoxazol-3-yl)sulphanilamide

N(sup 1)-(5-Methyl-3-isoxazolyl)sulfanilamide

N(sup 1)-(5-Methyl-3-isoxazolyl)sulphanilamide

N(sup1)-(5-Methyl-3-isoxazolyl)sulfanilamide

N^1-(5-methyl-3-isoxazolyl)-sulfanilamide

N1-(5-Methyl-3-isoxazolyl)sulfanilamide

N1-(5-Methyl-3-isoxazolyl)-sulfanilamide

N1-(5-Methyl-3-isoxazolyl)sulphanilamide

N1-(5-Methylisoxazol-3-yl)sulfanilamide

NCGC00016533-01

NCGC00016533-02

NCGC00021995-03

NCGC00021995-04

NCGC00021995-05

nchembio.221-comp24

Ndimethyl1-(5-methyl-3-isoxazolyl)-sulfanilamide

NINDS_000649

NSC 147832

NSC147832

Oprea1_114486

Oprea1_285680

Prestwick_453

Prestwick0_000177

Prestwick1_000177

Prestwick2_000177

Prestwick3_000177

Radonil

Ro 4-2130

Ro 6-2580/11

Ro-4-2130

S0361

S1915_Selleck

S7507_FLUKA

S7507_SIGMA

SAM002554930

Septran

SIM

Simsinomin

Sinomin

SMR000058223

SMX

Solfametossazolo

Solfametossazolo [DCIT]

SPBio_000896

SPBio_001994

Spectrum_000994

SPECTRUM1500550

Spectrum2_000788

Spectrum3_000584

Spectrum4_000345

Spectrum5_000982

STK007988

Sulfamethalazole

Sulfamethoxazol

sulfamethoxazole

Sulfamethoxazole

SULFAMETHOXAZOLE (8064-90-2 (TRIMETHOPRIM/SULFAMETHOXAZOLE)

Sulfamethoxazole (JP15/USP/INN)

Sulfamethoxazole [USAN:INN:JAN]

Sulfamethoxazole sodium

Sulfamethoxazole(usan)

Sulfamethoxazolum

Sulfamethoxazolum [INN-Latin]

Sulfamethoxizole

Sulfamethylisoxazole

Sulfametoxazol

Sulfametoxazol [INN-Spanish]

Sulfanilamide, N1-(5-methyl-3-isoxazolyl)- (8CI)

Sulfisomezole

Sulphamethalazole

Sulphamethoxazol

Sulphamethoxazole

Sulphamethoxazole BP 98

Sulpha-methoxizole

Sulpha-Methoxizole

Sulphamethylisoxazole

Sulphisomezole

TL8005058

TMP/SMX (MIXTURE))

Trib

UNII-JE42381TNV

Urobak

WLN: T5NOJ C1 EMSWR DZ

ZINC00089763

Trimethoprim

Approved, Vet_approved

Phase 3

738-70-5

5578

Synonyms:

2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine

2,4-diamino-5-(3,4,5-Trimethoxybenzyl)pyrimidine

46984_FLUKA

46984_RIEDEL

5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine

5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine

738-70-5

92131_FLUKA

92131_SIGMA

AB00052118

AB1004879

Abacin

Abaprim

AC-13572

AC1L1KNQ

AC1Q48DF

AI3-52594

AKOS001650069

Alcorim-F

Alprim

Anitrim

Antrima

Antrimox

Apo-Sulfatrim

ARONIS24118

AZT + TMP/SMX (mixture) combination

Bacdan

Bacidal

Bacide

Bacin

Bacta

Bacterial

Bacterial [Antibiotic]

Bacticel

Bactin

Bactoprim

Bactramin

Bactrim

Bactrim DS

Bactrim Pediatric

Baktar

BB_SC-2116

Bencole

Bethaprim

BIDD:GT0190

Biosulten

BPBio1_000215

BRD-K07208025-001-06-5

Briscotrim

BRN 0625127

BSPBio_000195

BSPBio_002245

BW 5672

BW 56-72

BW-56-72

C01965

CAS-738-70-5

CCRIS 2410

CHEBI:45924

CHEMBL22

Chemotrim

Chemotrin

CID5578

Cidal

Colizole

Colizole DS

Comox

component of Bactrim

component of Septra

Conprim

Cotrim

Cotrim D.S.

Cotrimel

CO-Trimoxazole

Co-Trimoxizole

CPD000035999

CPD0-1581

D00145

D014295

DB00440

Deprim

DivK1c_000589

Drylin

Duocide

EINECS 212-006-2

Esbesul

Espectrin

EU-0101271

Euctrim

Eusaprim

Exbesul

Fectrim

Fermagex

Fortrim

Futin

Gantaprim

Gantrim

HMS1568J17

HMS1921I03

HMS2090D14

HMS2092A10

HMS501N11

HSDB 6781

I06-0086

IDI1_000589

Idotrim

Ikaprim

Imexim

Instalac

Ipral

KBio1_000589

KBio2_000647

KBio2_003215

KBio2_005783

KBio3_001465

KBioGR_000863

KBioSS_000647

Kepinol

Kombinax

KSC-4-158

KUC103659N

Lagatrim

Lagatrim Forte

Laratrim

Lastrim

Lidaprim

Linaris

Lopac0_001271

Lopac-T-7883

LS-1627

Methoprim

Metoprim

Microtrim

MLS000079023

MLS001201740

MLS002303068

MolPort-001-826-685

Monoprim

Monotrim

Monotrimin

NCGC00016055-01

NCGC00016055-02

NCGC00016055-06

NCGC00016055-12

NCGC00024707-01

NCGC00024707-03

NCGC00024707-04

NCGC00024707-05

NCGC00024707-06

NCGC00024707-07

NCGC00024707-08

nchembio.108-comp1

nchembio.215-comp11

nchembio.221-comp23

NIH 204

NIH 204 (VAN)

NINDS_000589

Nopil

Novotrimel

NSC 106568

NSC106568

NSC-106568

Omstat

Oprea1_495058

Oraprim

Pancidim

Polytrim

Prestwick_485

Prestwick0_000208

Prestwick1_000208

Prestwick2_000208

Prestwick3_000208

Priloprim

Primosept

Primsol

Proloprim

Proloprim (TN)

Protrin

Purbal

Resprim

Resprim Forte

Roubac

Roubal

Salvatrim

SAM002264649

Septra

Septra DS

Septra Grape

Septrin

Septrin DS

Septrin Forte

Septrin S

Setprin

Sigaprim

Sinotrim

SMP2_000262

SMR000035999

Smz-Tmp

SPBio_000874

SPBio_002116

Spectrum_000167

SPECTRUM1500595

Spectrum2_000937

Spectrum3_000643

Spectrum4_000372

Spectrum5_001559

STK177322

Stopan

Streptoplus

Sugaprim

Sulfamar

Sulfamethoprim

Sulfamethoprim-DS

Sulfamethoxazole & Trimethoprim

Sulfatrim

Sulfatrim Pediatric

Sulfatrim-DS

Sulfatrim-SS

Sulfotrim

Sulfoxaprim

Sulmeprim

Sulmeprim Pediatric

Sulprim

Sulthrim

Sultrex

Sumetrolim

Supracombin

Suprim

Syraprim

T 7883

T2286

T7883_SIGMA

TCMDC-125538

Teleprim

Thiocuran

Tiempe

TL8005108

TMP/SMX (MIXTURE))

Tmp-Ratiopharm

Tocris-0650

Toprim

Trigonyl

Trimanyl

Trimesulf

Trimeth/Sulfa

Trimethioprim

Trimethopim(TMP)

trimethoprim

Trimethoprim

Trimethoprim & VRC3375

Trimethoprim (JAN/USP/INN)

Trimethoprim [USAN:BAN:INN:JAN]

Trimethoprime

Triméthoprime

Trimethoprime [INN-French]

Trimethoprimum

Trimethoprimum [INN-Latin]

Trimethopriom

Trimetoprim

Trimetoprim [DCIT]

Trimetoprim [Polish]

Trimetoprima

Trimetoprima [INN-Spanish]

Trimexazole

Trimexol

Trimez-IFSA

Trimezol

Trimogal

Trimono

Trimopan

Trimpex

Trimpex (TN)

Trimpex 200

Triprim

Trisul

Trisulcom

Trisulfam

Trisural

UNII-AN164J8Y0X

Unitrim

UPCMLD-DP132

UPCMLD-DP132:001

U-Prin

Uretrim

Urobactrim

Uro-D S

Uroplus

Uroplus DS

Uroplus SS

Uro-Septra

Utetrin

Velaten

Wellcoprim

Wellcoprin

WLN: T6N CNJ BZ DZ E1R CO1 DO1 EO1

WR 5949

Xeroprim

Zamboprim

ZINC06627681

Anti-Infective Agents

Phase 3

Renal Agents

Phase 3

Antimalarials

Phase 3

Antiparasitic Agents

Phase 3

Anti-Infective Agents, Urinary

Phase 3

Antiprotozoal Agents

Phase 3

Trimethoprim, Sulfamethoxazole Drug Combination

Phase 3

Anti-Bacterial Agents

Phase 3

Lecithin

Phase 1, Phase 2

Soy Bean

Phase 1, Phase 2

Pharmaceutical Solutions

Phase 1, Phase 2

Liver Extracts

Phase 1, Phase 2

Immunoglobulin G

Immunoglobulin M

Immunoglobulins

Antibodies

Interventional clinical trials:

(show all 15)

#	Name	Status	NCT ID	Phase	Drugs
1	Typhoid Vi Vaccine Effectiveness in a Population Older Than 5 Years of Age Living in an Endemic Area in Hechi, Guangxi, P.R. China: A Group-Randomized Controlled Demonstration Project	Completed	NCT00131833	Phase 4
2	Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central Vietnam. An Evaluation of Feasibility, Public Acceptability, Effectiveness and Cost-Effectiveness in Students	Completed	NCT00131820	Phase 4
3	Effectiveness of a Combined Vi Vaccination and Health Education Program on Reducing the Burden of Typhoid During Childhood: A Demonstration Project in Karachi	Completed	NCT00125047	Phase 4
4	Randomized Controlled Evaluation of the Vi Polysaccharide Vaccine Against Typhoid Fever in Eastern Kolkata, West Bengal, India	Completed	NCT00125008	Phase 4
5	Parallel Group, Double Blinded, 1:1, Randomized Controlled Phase III Trial of Co-trimoxazole Versus Azithromycin for the Treatment of Undifferentiated Fever In Nepal	Active, not recruiting	NCT02773407	Phase 3	Azithromycin;Co-trimoxazole
6	Safety Issue and Efficacy Study of Combining Mix Vaccine and Standard Therapy in the Treatment of Prostate Carcinoma Patient	Completed	NCT02338700	Phase 1, Phase 2
7	A Randomized, Double-Blind, Placebo-Controlled, Dose Escalation, In-Patient Phase I/II Study to Determine the Safety and Immunogenicity of Ty800 in Healthy Adult Subjects	Completed	NCT00269295	Phase 1, Phase 2	Placebo
8	Safety Issue and Efficacy Study of Combining Mix Vaccine and Standard Therapy in the Treatment of Breast Carcinoma Patient	Completed	NCT02338804	Phase 1, Phase 2
9	Safety Issue and Efficacy Study of Combining Mix Vaccine and Standard Therapy in the Treatment of Hepatocyte Carcinoma Patient	Completed	NCT02338778	Phase 1, Phase 2
10	Safety Issue and Efficacy Study of Combining Mix Vaccine and Standard Therapy in the Treatment of Pancreatic Carcinoma Patient	Completed	NCT02338752	Phase 1, Phase 2
11	Phase I Trial of a Live Oral Salmonella Enterica Serovar Paratyphi A Vaccine Harboring Mutations in guaBA and clpX	Completed	NCT01129453	Phase 1
12	Development of a Human Model of Salmonella Enterica Serovar Paratyphi A Challenge in Healthy Adult Volunteers	Unknown status	NCT02100397
13	Evaluation of Rapid Diagnostic Tests (RDT) in Association With Clinical and Laboratory Predictors for the Diagnosis of Neglected Tropical Diseases (NTD) in Patients Presenting With Persistent Fever (≥1 Week) in Cambodia, Nepal, Democratic Republic of the Congo and Sudan	Completed	NCT01766830
14	Investigating the Mechanisms and Determinants of Systemic and Mucosal Immunity to Salmonella Typhi and Salmonella Paratyphi A in naïve and Previously Exposed Individuals - A Challenge and Rechallenge Study	Active, not recruiting	NCT02192008
15	Investigating the Role of Typhoid Toxin in the Pathogenesis of Enteric Fever: A Double-blinded, Randomised, Outpatient Human Challenge Study.	Active, not recruiting	NCT03067961

Search NIH Clinical Center for Paratyphoid Fever

Cochrane evidence based reviews: paratyphoid fever

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Genetic Tests for Paratyphoid Fever

Sources

Anatomical Context for Paratyphoid Fever

The Foundational Model of Anatomy Ontology organs/tissues related to Paratyphoid Fever:

¹⁹

Intestine

MalaCards organs/tissues related to Paratyphoid Fever:

⁴⁰

Skin, Liver, Lung, Bone, Testes, Prostate, Breast

Sources

Publications for Paratyphoid Fever

Articles related to Paratyphoid Fever:

(show top 50) (show all 437)

#	Title	Authors	PMID	Year
1	[Epidemiology profil of fever typhoid in Meknes (Morocco) 2013-2016]. ⁶¹	Essayagh M...Essayagh T	31917023	2020
2	Characterization and protective efficacy of a Salmonella pathogenicity island 2 (SPI2) mutant of Salmonella Paratyphi A. ⁶¹	Yin J...Guo D	31610219	2019
3	Attenuated Salmonella Typhimurium expressing Salmonella Paratyphoid A O-antigen induces protective immune responses against two Salmonella strains. ⁶¹	Liu Q...Kong Q	31874075	2019
4	Spatial and Temporal Patterns of Typhoid and Paratyphoid Fever Outbreaks: A Worldwide Review, 1990-2018. ⁶¹	Kim S...Mogasale V	31665782	2019
5	Pediatric travelers presenting to an Australian emergency department (2014-2015): A retrospective, cross-sectional analysis. ⁶¹	Chong CH...Britton PN	30395939	2019
6	Antimicrobial resistance and genetic diversity of Salmonella enterica from eggs. ⁶¹	Xie T...Zhao J	31572578	2019
7	Loop-mediated isothermal amplification for paratyphoid fever - a proof-of-principle analysis. ⁶¹	Rojak S...Frickmann H	30761564	2019
8	Typhoid and Paratyphoid Fever - A Call to Action: Erratum. ⁶¹		31021958	2019
9	Salmonella Typhi outer membrane protein STIV is a potential candidate for vaccine development against typhoid and paratyphoid fever. ⁶¹	Das S...Das S	30952553	2019
10	The global burden of typhoid and paratyphoid fevers: a systematic analysis for the Global Burden of Disease Study 2017. ⁶¹	GBD 2017 Typhoid and Paratyphoid Collaborators	30792131	2019
11	Invasive Salmonella infections among children in Bintulu, Sarawak, Malaysian Borneo: a 6-year retrospective review. ⁶¹	Mohan A...Ooi MH	30999894	2019
12	Identifying different types of flood-sensitive diarrheal diseases from 2006 to 2010 in Guangxi, China. ⁶¹	Liu Z...Jiang B	30623882	2019
13	Epidemiology of Typhoid and Paratyphoid: Implications for Vaccine Policy. ⁶¹	Saha S...Saha SK	30845325	2019
14	Incidence of Typhoid and Paratyphoid Fevers Among Adolescents and Adults in Yangon, Myanmar. ⁶¹	Oo WT...Crump JA	30845332	2019
15	Salmonella infections in Canadian children. ⁶¹	Robinson JL	30833820	2019
16	Conservation of the OmpC Porin Among Typhoidal and Non-Typhoidal Salmonella Serovars. ⁶¹	Valero-Pacheco N...Lopez-Macias C	31998292	2019
17	Myositis associated with Salmonella paratyphi A bacteremia appears to be common. ⁶¹	Harris A...Aghoram R	30911492	2019
18	Analysis of research intensity on infectious disease by disease burden reveals which infectious diseases are neglected by researchers. ⁶¹	Furuse Y	30598444	2019
19	The Relationship Between Blood Sample Volume and Diagnostic Sensitivity of Blood Culture for Typhoid and Paratyphoid Fever: A Systematic Review and Meta-Analysis. ⁶¹	Antillon M...Pitzer VE	30307563	2018
20	Typhoid and paratyphoid fever: a call to action. ⁶¹	Gibani MM...Pollard AJ	30138141	2018
21	Global Trends in Typhoidal Salmonellosis: A Systematic Review. ⁶¹	Als D...Bhutta ZA	30047364	2018
22	Typhoid Fever: Way Forward. ⁶¹	Bhutta ZA...Levine MM	30047361	2018
23	Introductory Article on Global Burden and Epidemiology of Typhoid Fever. ⁶¹	Radhakrishnan A...Bhutta ZA	30047370	2018
24	The Burden of Typhoid Fever in South Africa: The Potential Impact of Selected Interventions. ⁶¹	Keddy KH...Benson FG	30047360	2018
25	Typhoidal Salmonella Trends in Thailand. ⁶¹	Techasaensiri C...Thisyakorn U	30047363	2018
26	Pan-genome Analysis of Ancient and Modern Salmonella enterica Demonstrates Genomic Stability of the Invasive Para C Lineage for Millennia. ⁶¹	Zhou Z...Achtman M	30033331	2018
27	Typhoidal Salmonella serovars: ecological opportunity and the evolution of a new pathovar. ⁶¹	Hiyoshi H...Baumler AJ	29790924	2018
28	Breast abscess due to Salmonella paratyphi A : Case reports with review of literature. ⁶¹	Agrawal S...Dhawan B	29862156	2018
29	Vaccines for preventing typhoid fever. ⁶¹	Milligan R...Neuberger A	29851031	2018
30	Seasonal dynamics of typhoid and paratyphoid fever. ⁶¹	Saad NJ...Pitzer VE	29720736	2018
31	Isolation and Identification of <i>Salmonella paratyphi </i>from Enteric Fever Patients at Different Hospitals of Quetta City. ⁶¹	Panezai M...Muhammad G	30724049	2018
32	Enteric fever among children: 50 cases in a French tertiary care centre. ⁶¹	Pommelet V...Faye A	30060197	2018
33	ECG abnormalities in a patient with paratyphoid fever. ⁶¹	Biber A...Schwartz E	30376076	2018
34	Molecular and Clinical Epidemiology of Salmonella Paratyphi A Isolated from Patients with Bacteremia in Nepal. ⁶¹	Sherchan JB...Hayakawa K	29016327	2017
35	[Spatial and temporal clustering characteristics of typhoid and paratyphoid fever and its change pattern in 3 provinces in southwestern China, 2001-2012]. ⁶¹	Wang LX...Kan B	29141338	2017
36	Vertical transmission of Salmonella enterica serotype Paratyphi A leading to abortion. ⁶¹	Sethi S...Angrup A	29255611	2017
37	Review of current typhoid fever vaccines, cross-protection against paratyphoid fever, and the European guidelines. ⁶¹	Zuckerman JN...Kantele A	28856924	2017
38	Spatio-temporal variations of typhoid and paratyphoid fevers in Zhejiang Province, China from 2005 to 2015. ⁶¹	Gu H...Jiang Q	28720886	2017
39	Salmonella Intracellular Lifestyles and Their Impact on Host-to-Host Transmission. ⁶¹	Pucciarelli MG...Garcia-Del Portillo F	28730976	2017
40	[Surveillance data on typhoid fever and paratyphoid fever in 2015, China]. ⁶¹	Liu FF...Liao QH	28647977	2017
41	The Epidemiology of Childhood Salmonella Infections in Alberta, Canada. ⁶¹	Faulder KE...Robinson JL	28306338	2017
42	Infectious Diseases and Tropical Cyclones in Southeast China. ⁶¹	Zheng J...Zhang Y	28481286	2017
43	Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model. ⁶¹	Dobinson HC...Pollard AJ	28158395	2017
44	Overview of the impact of Typhoid and Paratyphoid fever. Utility of Ty21a vaccine (Vivotif®). ⁶¹	Amicizia D...Gasparini R	28515625	2017
45	[An outbreak of paratyphoid fever in a county of Yunnan province, 2010-2011]. ⁶¹	Wang SK...Yan MY	28231666	2017
46	Self-reported infections during international travel and notifiable infections among returning international travellers, Sweden, 2009-2013. ⁶¹	Dahl V...Wallensten A	28753671	2017
47	Antimicrobial Resistance of Salmonella enterica Serovars Typhi and Paratyphi Isolates from a General Hospital in Karawaci, Tangerang, Indonesia: A Five-Year Review. ⁶¹	Hardjo Lugito NP...Cucunawangsih	28484494	2017
48	Antimicrobial susceptibility profile, treatment outcome and serotype distribution of clinical isolates of Salmonella enterica subspecies enterica: a 2-year study from Kerala, South India. ⁶¹	Harichandran D...Dinesh KR	28352198	2017
49	Diagnosis of Persistent Fever in the Tropics: Set of Standard Operating Procedures Used in the NIDIAG Febrile Syndrome Study. ⁶¹	Alirol E...Chappuis F	27812090	2016
50	Genomic analysis of Salmonella enterica serotype Paratyphi A during an outbreak in Cambodia, 2013-2015. ⁶¹	Kuijpers LMF...Weill FX	28348832	2016

Sources

Genes for Paratyphoid Fever

Genes related to Paratyphoid Fever (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PRKN	Parkin RBR E3 Ubiquitin Protein Ligase	Protein Coding	12.12	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	TNF	Tumor Necrosis Factor	Protein Coding	11.56	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	IFNGR1	Interferon Gamma Receptor 1	Protein Coding	11.42	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	CRP	C-Reactive Protein	Protein Coding	11.26	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	IFNG	Interferon Gamma	Protein Coding	11.25	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	CASP1	Caspase 1	Protein Coding	10.93	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	IL1R1	Interleukin 1 Receptor Type 1	Protein Coding	10.48	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	IL12B	Interleukin 12B	Protein Coding	6.99	GeneCards inferred via : Publications (show sections)
9	IL1A	Interleukin 1 Alpha	Protein Coding	6.99	GeneCards inferred via : Publications (show sections)
10	IL1B	Interleukin 1 Beta	Protein Coding	6.99	GeneCards inferred via : Publications (show sections)
11	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	6.99	GeneCards inferred via : Publications (show sections)
12	GALE	UDP-Galactose-4-Epimerase	Protein Coding	6.57	DISEASES inferred ¹⁵
13	SPI1	Spi-1 Proto-Oncogene	Protein Coding	6.15	DISEASES inferred ¹⁵
14	HGD	Homogentisate 1,2-Dioxygenase	Protein Coding	6.07	DISEASES inferred ¹⁵
15	CLPX	Caseinolytic Mitochondrial Matrix Peptidase Chaperone Subunit X	Protein Coding	5.97	DISEASES inferred ¹⁵
16	NPL	N-Acetylneuraminate Pyruvate Lyase	Protein Coding	5.94	DISEASES inferred ¹⁵
17	SLC11A1	Solute Carrier Family 11 Member 1	Protein Coding	5.9	DISEASES inferred ¹⁵

Sources

Variations for Paratyphoid Fever

Sources

Expression for Paratyphoid Fever

Search GEO for disease gene expression data for Paratyphoid Fever.

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Pathways for Paratyphoid Fever

Pathways related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show top 50) (show all 75)

#	Super pathways	Score	Top Affiliating Genes
1	Innate Immune System ⁶⁵ Show member pathways Immune System ⁶⁵ Neutrophil degranulation ⁶⁵	14.05	TNFRSF1A TNF SLC11A1 PRKN IL1R1 IL1B
2	PEDF Induced Signaling ⁶³ Show member pathways all-trans-Retinoic Acid Signaling in Brain ⁶³ Cytokine-cytokine receptor interaction ³⁶ Endothelin-1 Signaling Pathway ⁶³ Glucocorticoid Receptor Signaling ⁶³ IL-6 Pathway ⁶³ MIF Mediated Glucocorticoid Regulation ⁶³ MIF Regulation of Innate Immune Cells ⁶³ NFAT Signaling and Lymphocyte Interactions ⁶³ PGC1Alpha Pathway ⁶³ RAR-Gamma-RXR-Alpha Degradation ⁶³ STAT3 Pathway ⁶³	13.71	TNFRSF1A TNF IL1R1 IL1B IL1A IL12B
3	TGF-Beta Pathway ⁶³ Show member pathways JAK-STAT Pathway ⁶³ JNK Pathway ⁶³ MAPK Family Pathway ⁶³ Regulation of eIF4 and p70S6K ⁶³ SOCS Pathway ⁶³	13.58	TNFRSF1A TNF IL1R1 IL1B IL1A IL12B
4	Cytokine Signaling in Immune system ⁶⁵ Show member pathways Signaling by Interleukins ⁶⁵	13.41	TNFRSF1A TNF IL1R1 IL1B IL1A IL12B
5	PAK Pathway ⁶³ Show member pathways Antioxidant Action of Vitamin-C ⁶³ Epithelial Adherens Junctions ⁶³	13.34	TNFRSF1A TNF IL1R1 IL1B IL1A IL12B
6	IL-2 Pathway ⁶³ Show member pathways ErbB Family Pathway ⁶³ ErbB2-ErbB3 Heterodimers ⁶³ ErbB4 Pathway ⁶³ Growth Hormone Signaling ⁶³ HMGB1 Pathway ⁶³ IL-4 Pathway ⁶³ LPS Stimulated MAPK Signaling ⁶³ PACAP Signaling ⁶³ PI3K Signaling in B-Lymphocyte ⁶³ Prolactin Signaling ⁶³ Thrombopoietin Pathway ⁶³ TREM1 Pathway ⁶³ UVC-Induced MAPK Signaling ⁶³	13.25	TNFRSF1A TNF IL1R1 IL1B IL1A IFNGR1
7	Toll-like Receptor Signaling Pathway ¹ ³⁶ Show member pathways Chagas disease (American trypanosomiasis) ³⁶ Hepatitis B ³⁶ Hepatitis C ³⁶ NOD-like Receptor Signaling Pathways ⁶⁴ Regulation of toll-like receptor signaling pathway ¹	13.17	TNFRSF1A TNF IL1B IL12B IFNGR1 IFNG
8	Human cytomegalovirus infection ³⁶ Show member pathways Human immunodeficiency virus 1 infection ³⁶ Kaposi sarcoma-associated herpesvirus infection ³⁶	12.94	TNFRSF1A TNF IL1R1 IL1B IFNGR1
9	Allograft rejection ¹ ³⁶ Show member pathways Antigen processing and presentation ³⁶ Asthma ³⁶ Autoimmune thyroid disease ³⁶ CTL Mediated Apoptosis ⁶³ Graft-versus-host disease ³⁶ Intestinal immune network for IgA production ³⁶ THC Differentiation Pathway ⁶³ Type I diabetes mellitus ³⁶ Viral myocarditis ³⁶	12.89	TNF IL1B IL1A IL12B IFNG
10	Herpes simplex virus 1 infection ³⁶	12.85	TNFRSF1A TNF IL1B IL12B IFNGR1 IFNG
11	MAPK signaling pathway ³⁶ ¹	12.81	TNFRSF1A TNF IL1R1 IL1B IL1A CASP1
12	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways ⁶⁵ Show member pathways Cytosolic DNA-sensing pathway ³⁶ Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway ²² Negative regulators of RIG-I/MDA5 signaling ⁶⁵ NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 ⁶⁵ RIG-I-like Receptor Signaling ¹ RIG-I-like receptor signaling pathway ³⁶ TRAF3-dependent IRF activation pathway ⁶⁵ TRAF6 mediated IRF7 activation ⁶⁵ Virus Detection and Induction of Antiviral Signaling Pathways by RIG-I-like Receptors (RLR) ⁶⁴	12.8	TNF IL1B IL12B IFNG CASP1
13	Measles ³⁶ Show member pathways Epstein-Barr virus infection ³⁶ Influenza A ³⁶	12.79	TNFRSF1A TNF IL1B IL1A IL12B IFNGR1
14	NF-KappaB Family Pathway ⁶³ Show member pathways NF-KappaB (p50-p65) Pathway ⁶³	12.75	TNFRSF1A TNF IL1R1 IL1B IL1A
15	4-1BB Pathway ⁶³ Show member pathways CD27 Pathway ⁶³ CD40 Signaling ⁶³ CMV and MAPK Pathways ⁶³ NF-KappaB Activation by EBV ⁶³ NF-kappaB Activation by Viruses ⁶³ PKR Pathway ⁶³ SUMO Pathway ⁶³ TNFR2 Pathway ⁶³	12.71	TNFRSF1A TNF IL1R1 IL1B IL1A IFNGR1
16	Immune response NFAT in immune response ²² Show member pathways Immune response CD28 signaling ²² Immune response ICOS pathway in T-helper cell ²² Immune response T cell receptor signaling pathway ²²	12.68	TNFRSF1A TNF IL12B IFNGR1 IFNG
17	T cell receptor signaling pathway ³⁶ Show member pathways PD-L1 expression and PD-1 checkpoint pathway in cancer ³⁶ T-Cell antigen Receptor (TCR) Signaling Pathway ¹ T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection ¹	12.65	TNF IL1B IL1A IFNGR1 IFNG
18	NF-kappaB Signaling ⁴	12.62	TNFRSF1A TNF SPI1 IL1B IFNG
19	Th17 cell differentiation ³⁶ Show member pathways IL-22 Pathway ⁶³ Immune response IL-22 signaling pathway ²² Inflammatory bowel disease (IBD) ³⁶ Th1 and Th2 cell differentiation ³⁶	12.62	TNF IL1R1 IL1B IL1A IL12B IFNGR1
20	TRAF Pathway ⁶³ Show member pathways 14-3-3 Induced Apoptosis ⁶³ TNF Superfamily Pathway ⁶³ Toll-Like Receptors Pathway ⁶³	12.59	TNFRSF1A TNF IL1R1 IL1B IL1A IL12B
21	Shigellosis ³⁶	12.44	TNFRSF1A TNF IL1R1 IL1B CASP1
22	Human T-cell leukemia virus 1 infection ³⁶	12.38	TNFRSF1A TNF SPI1 IL1R1
23	Folate Metabolism ¹ Show member pathways Selenium Micronutrient Network ¹ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	12.38	TNF IL1B IFNG CRP
24	Pathogenic Escherichia coli infection ³⁶	12.37	TNFRSF1A TNF IL1R1 IL1B CASP1
25	IL-1 signaling pathway ¹ Show member pathways IL1-mediated signaling events ¹ Interleukin-1 signaling ⁶⁵ MAP3K8 (TPL2)-dependent MAPK1/3 activation ⁶⁵ Structural Pathway of Interleukin 1 (IL-1) ¹	12.35	IL1R1 IL1B IL1A CASP1
26	Immune response IFN alpha/beta signaling pathway ²² Show member pathways Cytokine Network ⁶³ Interferon alpha/beta signaling ⁶⁵ Regulation of IFNA signaling ⁶⁵	12.32	TNF IL1B IL1A IL12B IFNG
27	IL-1 Family Signaling Pathways ⁶⁴ Show member pathways Immune response IL-1 signaling pathway ²² Mucin expression in CF via TLRs, EGFR signaling pathways ²²	12.27	TNF IL1R1 IL1B IL1A
28	Apoptosis and survival Caspase cascade ²² Show member pathways Apoptosis and survival FAS signaling cascades ²² Breakdown of the nuclear lamina ⁶⁵ Caspase cascade in apoptosis ¹ Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation ¹ FasL/ CD95L signaling ⁶⁵ Influenza A virus infection ¹	12.27	TNFRSF1A TNF IL1A CASP1
29	Bacterial infections in CF airways ²² Show member pathways IL-1 beta-dependent CFTR expression ²² Immune response Bacterial infections in normal airways ²² Immune response TLR signaling pathways ²²	12.27	TNF IL1R1 IL1B IFNGR1 IFNG
30	C-type lectin receptor signaling pathway ³⁶ Show member pathways Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways ⁶⁴	12.26	TNF IL1B IL12B CASP1
31	Colorectal Cancer Metastasis ⁶³	12.24	TNFRSF1A TNF IFNGR1 IFNG
32	Toll Comparative Pathway ⁶³ Show member pathways IL-1 Pathway ⁶³ Immune response MIF in innate immunity response ²² iNOS Signaling ⁶³ TLR-TRIF Pathway ⁶³	12.24	TNF SPI1 IL1R1 IL1B IL1A IFNGR1
33	Toxoplasmosis ³⁶ Show member pathways Leishmaniasis ³⁶	12.19	TNFRSF1A TNF IL1B IL1A IL12B IFNGR1
34	Tuberculosis ³⁶	12.12	TNFRSF1A TNF IL1B IL1A IL12B IFNGR1
35	Spinal Cord Injury ¹	12.08	TNF IL1R1 IL1B IL1A IFNG
36	Fluid shear stress and atherosclerosis ³⁶	12.08	TNFRSF1A TNF IL1R1 IL1B IL1A IFNG
37	Interleukin-4 and 13 signaling ⁶⁵	12.06	TNF IL1B IL1A IL12B
38	IL12-mediated signaling events ¹ Show member pathways Immune response IL-12-induced IFN-gamma production ²²	12.05	IL1R1 IL1B IL12B IFNG
39	Necroptosis ³⁶ Show member pathways Nanoparticle triggered regulated necrosis ¹	12.04	TNFRSF1A TNF IL1B IL1A IFNGR1 IFNG
40	Th1 Differentiation Pathway ⁶⁴ Show member pathways IL27-mediated signaling events ¹ Th17 Differentiation Pathway ⁶⁴	12.02	TNF IL1R1 IL1B IL12B IFNGR1 IFNG
41	NF-kappa B signaling pathway ³⁶	12	TNFRSF1A TNF IL1R1 IL1B
42	Amoebiasis ³⁶	11.99	TNF IL1R1 IL1B IL12B IFNG
43	Hematopoietic cell lineage ³⁶	11.98	TNF IL1R1 IL1B IL1A
44	Senescence and Autophagy in Cancer ¹	11.95	IL1B IL1A IFNG
45	Rheumatoid arthritis ³⁶	11.95	TNF IL1B IL1A IFNG
46	Immune response IFN gamma signaling pathway ²² Show member pathways IFN-gamma pathway ¹	11.93	IL1B IFNGR1 IFNG CASP1
47	AGE-RAGE signaling pathway in diabetic complications ³⁶	11.92	TNF IL1B IL1A
48	Salmonella infection (KEGG) ³⁶	11.86	IL1B IL1A IFNGR1 IFNG CASP1
49	Innate Lymphoid Cell Differentiation Pathways ⁶⁴	11.85	TNF SPI1 IL1R1 IL1B IFNG
50	Dendritic Cells Developmental Lineage Pathway ⁶⁴	11.83	TNF SPI1 IL1B IFNG

Sources

GO Terms for Paratyphoid Fever

Biological processes related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show all 50)

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of transcription by RNA polymerase II	GO:0045944	10.17	TNFRSF1A TNF SPI1 SLC11A1 PRKN IL1B
2	immune response	GO:0006955	10.05	TNF SLC11A1 IL1R1 IL1B IL1A IFNG
3	cell surface receptor signaling pathway	GO:0007166	9.96	TNFRSF1A IL1R1 IL12B IFNG
4	inflammatory response	GO:0006954	9.95	TNFRSF1A TNF SLC11A1 IL1R1 IL1B IL1A
5	cellular response to lipopolysaccharide	GO:0071222	9.91	TNF IL1B IL1A IL12B CASP1
6	response to virus	GO:0009615	9.88	TNF IFNGR1 IFNG
7	interleukin-1-mediated signaling pathway	GO:0070498	9.87	IL1R1 IL1B IL1A
8	positive regulation of JNK cascade	GO:0046330	9.86	TNF IL1B IL1A
9	regulation of inflammatory response	GO:0050727	9.86	TNF IL1R1 CASP1
10	positive regulation of inflammatory response	GO:0050729	9.86	TNFRSF1A TNF IL1B IL12B
11	cellular response to mechanical stimulus	GO:0071260	9.85	TNFRSF1A IL1B CASP1
12	positive regulation of I-kappaB kinase/NF-kappaB signaling	GO:0043123	9.85	TNFRSF1A TNF PRKN IL1B IL1A CASP1
13	regulation of insulin secretion	GO:0050796	9.83	TNF IL1B IFNG
14	positive regulation of tyrosine phosphorylation of STAT protein	GO:0042531	9.83	TNFRSF1A TNF IL12B IFNG
15	positive regulation of NIK/NF-kappaB signaling	GO:1901224	9.82	TNF IL1B IL12B
16	positive regulation of interleukin-6 production	GO:0032755	9.82	TNF IL1B IL1A
17	positive regulation of nitric oxide biosynthetic process	GO:0045429	9.8	TNF IL1B IFNG
18	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001240	9.79	TNF IL1B IL1A
19	microglial cell activation	GO:0001774	9.77	TNF IFNGR1 IFNG
20	positive regulation of phagocytosis	GO:0050766	9.76	TNF SLC11A1 IL1B IFNG
21	positive regulation of gene expression	GO:0010628	9.76	TNF SLC11A1 PRKN IL1B IL1A IFNGR1
22	positive regulation of osteoclast differentiation	GO:0045672	9.74	TNF IL12B IFNG
23	positive regulation of amyloid-beta formation	GO:1902004	9.72	TNF IFNGR1 IFNG
24	positive regulation of interleukin-6 biosynthetic process	GO:0045410	9.71	TNF IL1B
25	positive regulation of membrane protein ectodomain proteolysis	GO:0051044	9.71	TNF IL1B IFNG
26	positive regulation of interleukin-2 biosynthetic process	GO:0045086	9.7	IL1B IL1A
27	negative regulation of interleukin-17 production	GO:0032700	9.7	IL12B IFNG
28	regulation of interferon-gamma-mediated signaling pathway	GO:0060334	9.7	IFNGR1 IFNG
29	positive regulation of neuroinflammatory response	GO:0150078	9.69	TNF IL1B
30	positive regulation of ceramide biosynthetic process	GO:2000304	9.69	TNFRSF1A TNF
31	positive regulation of granulocyte macrophage colony-stimulating factor production	GO:0032725	9.69	IL1B IL12B
32	positive regulation of tumor necrosis factor-mediated signaling pathway	GO:1903265	9.68	PRKN CASP1
33	positive regulation of smooth muscle cell apoptotic process	GO:0034393	9.67	IL12B IFNG
34	negative regulation of lipid storage	GO:0010888	9.67	TNF CRP
35	positive regulation of T-helper 1 type immune response	GO:0002827	9.67	SLC11A1 IL12B
36	positive regulation of chemokine biosynthetic process	GO:0045080	9.67	TNF IL1B IFNG
37	death-inducing signaling complex assembly	GO:0071550	9.66	TNFRSF1A TNF
38	ectopic germ cell programmed cell death	GO:0035234	9.65	IL1B IL1A
39	negative regulation of amyloid-beta clearance	GO:1900222	9.65	TNF IFNGR1 IFNG
40	positive regulation of T-helper 1 cell cytokine production	GO:2000556	9.64	IL1R1 IL1B
41	positive regulation of fever generation	GO:0031622	9.63	TNF IL1B
42	sequestering of triglyceride	GO:0030730	9.62	TNF IL1B
43	fever generation	GO:0001660	9.61	IL1B IL1A
44	regulation of establishment of endothelial barrier	GO:1903140	9.61	TNFRSF1A TNF IL1B
45	positive regulation of vitamin D biosynthetic process	GO:0060557	9.59	TNF IFNG
46	positive regulation of nitrogen compound metabolic process	GO:0051173	9.58	TNF IFNG
47	astrocyte activation	GO:0048143	9.56	TNF IL1B IFNGR1 IFNG
48	positive regulation of calcidiol 1-monooxygenase activity	GO:0060559	9.5	TNF IL1B IFNG
49	positive regulation of interferon-gamma production	GO:0032729	9.35	TNF SLC11A1 IL1R1 IL1B IL12B
50	cytokine-mediated signaling pathway	GO:0019221	9.23	TNFRSF1A TNF IL1R1 IL1B IL1A IL12B

Molecular functions related to Paratyphoid Fever according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	identical protein binding	GO:0042802	9.56	TNF PRKN NPL IL12B HGD GALE
2	interleukin-1 receptor binding	GO:0005149	9.16	IL1B IL1A
3	cytokine activity	GO:0005125	9.02	TNF IL1B IL1A IL12B IFNG

Sources

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