MCID: PRN006
MIFTS: 15

Parenchymatous Neurosyphilis

Categories: Infectious diseases, Neuronal diseases

Aliases & Classifications for Parenchymatous Neurosyphilis

MalaCards integrated aliases for Parenchymatous Neurosyphilis:

Name: Parenchymatous Neurosyphilis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050490

Summaries for Parenchymatous Neurosyphilis

Disease Ontology : 12 A tertiary neurosyphilis that results when chronic meningoencephalitis causes destruction of cortical parenchyma. The infection has symptom irritability, has symptom difficulty concentrating, has symptom deterioration of memory, has symptom defective judgment, has symptom headaches, has symptom insomnia, has symptom fatigue, and has symptom lethargy.

MalaCards based summary : Parenchymatous Neurosyphilis is related to neurosyphilis and tabes dorsalis, and has symptoms including irritability, difficulty concentrating and deterioration of memory. An important gene associated with Parenchymatous Neurosyphilis is EXTL3 (Exostosin Like Glycosyltransferase 3). Affiliated tissues include brain.

Related Diseases for Parenchymatous Neurosyphilis

Diseases related to Parenchymatous Neurosyphilis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 neurosyphilis 10.3
2 tabes dorsalis 8.9 EXTL3 MBP
3 tertiary neurosyphilis 8.5 EXTL3 FLYWCH1 MBP

Symptoms & Phenotypes for Parenchymatous Neurosyphilis

Symptoms:

12
  • irritability
  • difficulty concentrating
  • deterioration of memory
  • defective judgment
  • headaches
  • insomnia
  • fatigue
  • lethargy

Drugs & Therapeutics for Parenchymatous Neurosyphilis

Search Clinical Trials , NIH Clinical Center for Parenchymatous Neurosyphilis

Genetic Tests for Parenchymatous Neurosyphilis

Anatomical Context for Parenchymatous Neurosyphilis

MalaCards organs/tissues related to Parenchymatous Neurosyphilis:

41
Brain

Publications for Parenchymatous Neurosyphilis

Articles related to Parenchymatous Neurosyphilis:

# Title Authors Year
1
Late-stage parenchymatous neurosyphilis presenting as general paresis of insane, Poland a89 case report ( 28230337 )
2016
2
A Fatal Fall Associated With Undiagnosed Parenchymatous Neurosyphilis. ( 24317097 )
2013
3
Parenchymatous neurosyphilis. ( 11731886 )
2001
4
Permeability of the blood-brain barrier to penicillin in cases of parenchymatous neurosyphilis. ( 14824880 )
1951

Variations for Parenchymatous Neurosyphilis

Expression for Parenchymatous Neurosyphilis

Search GEO for disease gene expression data for Parenchymatous Neurosyphilis.

Pathways for Parenchymatous Neurosyphilis

GO Terms for Parenchymatous Neurosyphilis

Sources for Parenchymatous Neurosyphilis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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