Parietal Lobe Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MalaCards based summary: Parietal Lobe Neoplasm, also known as malignant neoplasm of parietal lobe, is related to parietal lobe ependymoma and oral rhabdomyosarcoma. An important gene associated with Parietal Lobe Neoplasm is MYOG (Myogenin), and among its related pathways/superpathways are Regulation of retinoblastoma protein and Mesenchymal Stem Cells and Lineage-specific Markers. Affiliated tissues include parietal lobe, brain and eye.

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Related Diseases for Parietal Lobe Neoplasm

Diseases related to Parietal Lobe Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 237)

#	Related Disease	Score	Top Affiliating Genes
1	parietal lobe ependymoma	11.2
2	oral rhabdomyosarcoma	10.2	MYOG MYOD1
3	gallbladder sarcoma	10.2	MYOG MYOD1
4	skeletal muscle neoplasm	10.2	MYOG MYOD1
5	botryoid rhabdomyosarcoma	10.2	MYOG MYOD1
6	prostate embryonal rhabdomyosarcoma	10.2	MYOG MYOD1
7	inflammatory leiomyosarcoma	10.2	MYOG MYOD1
8	prostate rhabdomyosarcoma	10.2	MYOG MYOD1
9	spindle cell rhabdomyosarcoma	10.2	MYOG MYOD1
10	kidney cortex disease	10.2	SMARCB1 MYOG
11	blastoma	10.2	MYOG ENO2
12	orbit rhabdomyosarcoma	10.2	MYOG MYOD1
13	progressive relapsing multiple sclerosis	10.2	MYOG MYOD1
14	clear cell basal cell carcinoma	10.2	MYOG KRT5
15	optic nerve astrocytoma	10.1	SMARCB1 ENO2
16	askin's tumor	10.1	MYOG ENO2
17	gas gangrene	10.1	MYOG MYOD1
18	ovarian large-cell neuroendocrine carcinoma	10.1	SMARCB1 ENO2
19	ovarian small cell carcinoma	10.1	SMARCB1 ENO2
20	cloacogenic carcinoma	10.1	KRT5 ENO2
21	middle ear adenoma	10.1	KRT5 ENO2
22	auditory system benign neoplasm	10.1	KRT5 ENO2
23	vulvar apocrine adenocarcinoma	10.1	KRT5 ENO2
24	ureter small cell carcinoma	10.1	KRT5 ENO2
25	extraosseous chondrosarcoma	10.1	SMARCB1 ENO2
26	small cell carcinoma	10.1	KRT5 ENO2
27	sensory organ benign neoplasm	10.1	KRT5 ENO2
28	nasal cavity olfactory neuroblastoma	10.1	KRT5 ENO2
29	cystic basal cell carcinoma	10.1	KRT5 ENO2
30	lymphoepithelioma-like carcinoma	10.1	KRT5 ENO2
31	basaloid squamous cell carcinoma	10.1	KRT5 ENO2
32	goblet cell carcinoid	10.1	ENO2 CDH1
33	rhabdoid meningioma	10.1	SMARCB1 GFAP
34	esophageal adenosquamous carcinoma	10.1	KRT5 CDH1
35	endobronchial lipoma	10.0	KRT5 ENO2
36	emery-dreifuss muscular dystrophy 2, autosomal dominant	10.0	MYOG MYOD1
37	verrucous carcinoma	10.0	KRT5 CDH1
38	breast rhabdomyosarcoma	10.0	SMARCB1 MYOG MYOD1
39	lobular neoplasia	10.0	KRT5 CDH1
40	anaplastic ependymoma	10.0	SMARCB1 GFAP
41	middle ear adenocarcinoma	10.0	KRT5 GFAP
42	granular cell tumor	10.0	GFAP ENO2
43	large cell neuroendocrine carcinoma	10.0	KRT5 ENO2
44	cerebral neuroblastoma	10.0	GFAP ENO2
45	spondylometaphyseal dysplasia with corneal dystrophy	10.0	MYOD1 GFAP
46	partial cryptophthalmia	10.0	GFAP ENO2
47	cerebellopontine angle primitive neuroectodermal tumor	10.0	GFAP ENO2
48	pleomorphic rhabdomyosarcoma	10.0	MYOG MYOD1
49	rhabdoid cancer	10.0	SMARCB1 MYOD1
50	pineocytoma	10.0	GFAP ENO2

Graphical network of the top 20 diseases related to Parietal Lobe Neoplasm:

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Symptoms & Phenotypes for Parietal Lobe Neoplasm

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Drugs & Therapeutics for Parietal Lobe Neoplasm

Search Clinical Trials, NIH Clinical Center for Parietal Lobe Neoplasm

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Genetic Tests for Parietal Lobe Neoplasm

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Anatomical Context for Parietal Lobe Neoplasm

Organs/tissues related to Parietal Lobe Neoplasm:

FMA: Parietal Lobe

MalaCards : Parietal Lobe, Brain, Eye

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Publications for Parietal Lobe Neoplasm

Articles related to Parietal Lobe Neoplasm:

#	Title	Authors	PMID	Year
1	Malignant meningioma with jugular vein invasion and carotid artery extension: A case report and review of the literature. ⁶²	Chen HY...Su JP	33344612	2020
2	Malignant supratentorial glial-neuronal neoplasms: report of two cases and review of the literature. ⁶²	McLendon RE...Friedman HS	9167602	1997

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Genes for Parietal Lobe Neoplasm

Genes related to Parietal Lobe Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MYOG	Myogenin	Protein Coding	4.09	DISEASES inferred ¹⁴
2	SMARCB1	SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1	Protein Coding	4.01	DISEASES inferred ¹⁴
3	MYOD1	Myogenic Differentiation 1	Protein Coding	3.97	DISEASES inferred ¹⁴
4	KRT5	Keratin 5	Protein Coding	3.77	DISEASES inferred ¹⁴
5	ENO2	Enolase 2	Protein Coding	3.53	DISEASES inferred ¹⁴
6	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	3.49	DISEASES inferred ¹⁴
7	CD34	CD34 Molecule	Protein Coding	2.86	DISEASES inferred ¹⁴
8	CDH1	Cadherin 1	Protein Coding	2.79	DISEASES inferred ¹⁴

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Variations for Parietal Lobe Neoplasm

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Expression for Parietal Lobe Neoplasm

Search GEO for disease gene expression data for Parietal Lobe Neoplasm.

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Pathways for Parietal Lobe Neoplasm

Pathways related to Parietal Lobe Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Regulation of retinoblastoma protein ⁶¹	10.9	SMARCB1 MYOD1
2	Mesenchymal Stem Cells and Lineage-specific Markers ⁶⁵	10.78	MYOG MYOD1 CD34
3	Myogenesis ⁶⁶	10.43	MYOG MYOD1

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GO Terms for Parietal Lobe Neoplasm

Biological processes related to Parietal Lobe Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cellular response to lithium ion	GO:0071285	9.62	MYOG CDH1
2	positive regulation of skeletal muscle fiber development	GO:0048743	9.46	MYOG MYOD1
3	myotube differentiation	GO:0014902	9.26	MYOG MYOD1
4	muscle cell fate commitment	GO:0042693	9.26	MYOG MYOD1
5	positive regulation of myoblast differentiation	GO:0045663	9.1	SMARCB1 MYOG MYOD1

Molecular functions related to Parietal Lobe Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	DNA-binding transcription activator activity	GO:0001216	8.62	MYOG MYOD1

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Sources for Parietal Lobe Neoplasm

¹ BitterDB

² CDC

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²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

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²⁹ HMDB

³⁰ HPO

³¹ ICD10

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³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

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⁴⁷ NCBI Bookshelf

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⁵¹ NIH Clinical Center

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⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

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⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: PRT023 MIFTS: 25	Parietal Lobe Neoplasm Categories: Cancer diseases, Neuronal diseases	Data Licensing For inquiries, contact: [email protected]
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