PARK16
MCID: PRK058
MIFTS: 17

Parkinson Disease 16 (PARK16)

Categories: Genetic diseases, Mental diseases, Metabolic diseases, Muscle diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Parkinson Disease 16

MalaCards integrated aliases for Parkinson Disease 16:

Name: Parkinson Disease 16 56 29 13 71
Park16 56

Classifications:



External Ids:

OMIM 56 613164
OMIM Phenotypic Series 56 PS168600
UMLS 71 C2751012

Summaries for Parkinson Disease 16

MalaCards based summary : Parkinson Disease 16, also known as park16, is related to parkinson disease, late-onset and parkinson disease 8, autosomal dominant. An important gene associated with Parkinson Disease 16 is PARK16 (Parkinson Disease 16 (Susceptibility)).

More information from OMIM: 613164 PS168600

Related Diseases for Parkinson Disease 16

Symptoms & Phenotypes for Parkinson Disease 16

Clinical features from OMIM:

613164

Drugs & Therapeutics for Parkinson Disease 16

Search Clinical Trials , NIH Clinical Center for Parkinson Disease 16

Genetic Tests for Parkinson Disease 16

Genetic tests related to Parkinson Disease 16:

# Genetic test Affiliating Genes
1 Parkinson Disease 16 29

Anatomical Context for Parkinson Disease 16

Publications for Parkinson Disease 16

Articles related to Parkinson Disease 16:

(show top 50) (show all 57)
# Title Authors PMID Year
1
Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease. 61 56
21425343 2011
2
An independent replication of PARK16 in Asian samples. 61 56
21172849 2010
3
Analysis of GWAS-linked loci in Parkinson disease reaffirms PARK16 as a susceptibility locus. 56 61
20697102 2010
4
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. 56 61
19915576 2009
5
Genome-wide association study reveals genetic risk underlying Parkinson's disease. 56 61
19915575 2009
6
EFNS/MDS-ES/ENS [corrected] recommendations for the diagnosis of Parkinson's disease. 6
23279440 2013
7
Parkinson Disease Overview 6
20301402 2004
8
Parkinson's disease GWAS-linked Park16 carriers show greater motor progression. 61
30814270 2019
9
SNPs rs11240569, rs708727, and rs823156 in SLC41A1 Do Not Discriminate Between Slovak Patients with Idiopathic Parkinson's Disease and Healthy Controls: Statistics and Machine-Learning Evidence. 61
31546642 2019
10
Functional association between NUCKS1 gene and Parkinson disease: A potential susceptibility biomarker. 61
31719764 2019
11
Association between rs823128 polymorphism and the risk of Parkinson's disease: A meta-analysis. 61
29191693 2018
12
Gene Co-Expression Network Analysis Implicates microRNA Processing in Parkinson's Disease Pathogenesis. 61
30089309 2018
13
Rab29 activation of the Parkinson's disease-associated LRRK2 kinase. 61
29212815 2018
14
Association between PARK16 and Parkinson's disease: A meta-analysis. 61
28807727 2017
15
Associations of rs823128, rs1572931, and rs823156 polymorphisms with reduced Parkinson's disease risks. 61
28749816 2017
16
Rabs, Membrane Dynamics, and Parkinson's Disease. 61
27925204 2017
17
RAB7L1 promoter polymorphism and risk of Parkinson's disease; a case-control study. 61
28245721 2017
18
Combined Diffusion Tensor Imaging and Apparent Transverse Relaxation Rate Differentiate Parkinson Disease and Atypical Parkinsonism. 61
28364007 2017
19
Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study. 61
27814993 2017
20
Genome-wide association study of Parkinson's disease in East Asians. 61
28011712 2017
21
PARK16 is associated with PD in the Malaysian population. 61
27174169 2016
22
Objective Measures of Swallowing Function Applied to the Dysphagia Population: A One Year Experience. 61
27106909 2016
23
Mutation in ADORA1 identified as likely cause of early-onset parkinsonism and cognitive dysfunction. 61
27134041 2016
24
Comprehensive promoter level expression quantitative trait loci analysis of the human frontal lobe. 61
27287230 2016
25
PARK16 polymorphisms, interaction with smoking, and sporadic Parkinson's disease in Japan. 61
26944116 2016
26
SLC41A1 and TRPM7 in magnesium homeostasis and genetic risk for Parkinson's disease. 61
31187092 2016
27
Exploring the Effects of Genetic Variants on Clinical Profiles of Parkinson's Disease Assessed by the Unified Parkinson's Disease Rating Scale and the Hoehn-Yahr Stage. 61
27299523 2016
28
Genetic analysis of SLC41A1 in Chinese Parkinson's disease patients. 61
26308152 2015
29
Patterns of linkage disequilibrium at PARK16 may explain variances in genetic association studies. 61
25758099 2015
30
A commentary on fine mapping and resequencing of the PARK16 locus in Parkinson's disease. 61
26134513 2015
31
PARK16 haplotypes and the importance of protective genetic factors in Parkinson's disease. 61
26108144 2015
32
Fine mapping and resequencing of the PARK16 locus in Parkinson's disease. 61
25855069 2015
33
Association between PARK16 gene polymorphisms and susceptibility of Parkinson's disease in a Chinese population. 61
25966061 2015
34
Polygenic determinants of Parkinson's disease in a Chinese population. 61
25623333 2015
35
Association analysis of PARK16-18 variants and Parkinson's disease in a Chinese population. 61
24373818 2014
36
Alzheimer's disease and Parkinson's disease genome-wide association study top hits and risk of Parkinson's disease in Korean population. 61
23820587 2013
37
Association between PARK16 and Parkinson's disease in the Han Chinese population: a meta-analysis. 61
23747047 2013
38
Association of five SNPs at the PARK16 locus as a susceptibility locus with Parkinson's disease for forensic application. 61
24303760 2013
39
RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk. 61
23395371 2013
40
Parallel PARKing: Parkinson's genes function in common pathway. 61
23395366 2013
41
GWAS risk factors in Parkinson's disease: LRRK2 coding variation and genetic interaction with PARK16. 61
24319646 2013
42
Substitution p.A350V in Na⁺/Mg²⁺ exchanger SLC41A1, potentially associated with Parkinson's disease, is a gain-of-function mutation. 61
23976986 2013
43
Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants. 61
22658533 2012
44
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 61
22438815 2012
45
Association of sequence alterations in the putative promoter of RAB7L1 with a reduced parkinson disease risk. 61
22232350 2012
46
Genetic variants in sporadic Parkinson's disease: East vs West. 61
22166457 2012
47
An association between the PARK16 locus and Parkinson's disease in a cohort from eastern China. 61
21840748 2011
48
Genetic variants in the RAB7L1 and SLC41A1 genes of the PARK16 locus in Chinese Parkinson's disease patients. 61
21812739 2011
49
Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population. 61
21812969 2011
50
A two-stage meta-analysis identifies several new loci for Parkinson's disease. 61
21738488 2011

Variations for Parkinson Disease 16

Expression for Parkinson Disease 16

Search GEO for disease gene expression data for Parkinson Disease 16.

Pathways for Parkinson Disease 16

GO Terms for Parkinson Disease 16

Sources for Parkinson Disease 16

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
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30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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