Aliases & Classifications for Paronychia

MalaCards integrated aliases for Paronychia:

Name: Paronychia 12 76 29 55 44 15
Paronychia Inflammation 12 73
Onychia and Paronychia of Finger 12
Onychia and Paronychia of Toe 12
Fungal Nail Infection 12
Infected Nailfold 12
Onychomycosis 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13117
ICD10 33 L03.0
MeSH 44 D010304
NCIt 50 C79702

Summaries for Paronychia

Disease Ontology : 12 A nail disease characterized by often-tender bacterial or fungal hand infection or foot infection due to either bacteria or fungus (Candida albicans) where the nail and skin meet at the side or the base of a finger or toe nail. The infection can start suddenly (acute paronychia) or gradually (chronic paronychia). Puss is usually present, along with gradual thickening and browning discoloration of the nail plate.

MalaCards based summary : Paronychia, also known as paronychia inflammation, is related to aggressive digital papillary adenocarcinoma and adenocarcinoma. An important gene associated with Paronychia is EGFR (Epidermal Growth Factor Receptor), and among its related pathways/superpathways are ERK Signaling and HIV Life Cycle. The drugs Cetuximab and Fluorouracil have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and t cells, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 76 Paronychia is a nail disease that is an often-tender bacterial or fungal infection of the hand or foot... more...

Related Diseases for Paronychia

Diseases related to Paronychia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 126)
# Related Disease Score Top Affiliating Genes
1 aggressive digital papillary adenocarcinoma 29.7 HRAS KRAS
2 adenocarcinoma 28.6 EGFR HRAS KRAS
3 squamous cell carcinoma 28.6 EGFR HRAS KRAS
4 candidal paronychia 11.9
5 neuropathy, hereditary sensory and autonomic, type iia 11.0
6 luminal breast carcinoma 10.3 EGFR MTOR
7 ethmoid sinus cancer 10.2 EGFR HRAS
8 ethmoid sinus adenocarcinoma 10.2 EGFR HRAS
9 sigmoid neoplasm 10.1 HRAS KRAS
10 apocrine adenoma 10.1 HRAS KRAS
11 schimmelpenning-feuerstein-mims syndrome 10.1 HRAS KRAS
12 periampullary adenoma 10.1 HRAS KRAS
13 bile duct cysts 10.1 HRAS KRAS
14 bronchiolo-alveolar adenocarcinoma 10.1 EGFR KRAS
15 pemphigus 10.1
16 secondary hypertrophic osteoarthropathy 10.1 HRAS KRAS
17 nasal cavity adenocarcinoma 10.1 HRAS KRAS
18 anal canal adenocarcinoma 10.1 HRAS KRAS
19 ovary serous adenocarcinoma 10.1 HRAS KRAS
20 nail disease 10.1 EGFR KRAS
21 ampulla of vater neoplasm 10.1 HRAS KRAS
22 ovarian cystadenocarcinoma 10.1 HRAS KRAS
23 pulmonary blastoma 10.1 EGFR KRAS
24 pemphigus vulgaris, familial 10.1
25 pemphigus vulgaris 10.1
26 nevus, epidermal 10.1 HRAS KRAS
27 biliary papillomatosis 10.1 HRAS KRAS
28 colloid carcinoma of the pancreas 10.1 HRAS KRAS
29 mixed cell type cancer 10.1 HRAS KRAS
30 leishmaniasis 10.0
31 pyogenic granuloma 10.0
32 ovary adenocarcinoma 10.0 HRAS KRAS
33 adenosquamous pancreas carcinoma 10.0 HRAS KRAS
34 core binding factor acute myeloid leukemia 10.0 HRAS KRAS
35 biliary tract neoplasm 10.0 HRAS KRAS
36 duodenum cancer 10.0 HRAS KRAS
37 liver angiosarcoma 10.0 HRAS KRAS
38 cutaneous leishmaniasis 10.0
39 penile cancer 10.0 EGFR HRAS
40 lacrimal gland adenocarcinoma 10.0 HRAS KRAS
41 cecum adenocarcinoma 10.0 HRAS KRAS
42 pulmonic stenosis 10.0 HRAS KRAS
43 costello syndrome 10.0 HRAS KRAS
44 mucinous adenocarcinoma 10.0 EGFR KRAS
45 dermatitis 10.0
46 bile duct adenocarcinoma 10.0 HRAS KRAS
47 small intestinal adenocarcinoma 9.9 EGFR KRAS
48 gastrointestinal system benign neoplasm 9.9 HRAS KRAS
49 skin squamous cell carcinoma 9.9 HRAS KRAS
50 intestinal benign neoplasm 9.9 HRAS KRAS

Graphical network of the top 20 diseases related to Paronychia:



Diseases related to Paronychia

Symptoms & Phenotypes for Paronychia

GenomeRNAi Phenotypes related to Paronychia according to GeneCards Suite gene sharing:

26 (show all 32)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 10.73 MTOR EGFR HRAS KRAS
2 Decreased viability GR00106-A-0 10.73 KRAS
3 Decreased viability GR00221-A-1 10.73 MTOR MAP2K7 KRAS EGFR HRAS
4 Decreased viability GR00221-A-2 10.73 KRAS HRAS
5 Decreased viability GR00221-A-3 10.73 WNK1 HRAS
6 Decreased viability GR00221-A-4 10.73 MTOR WNK1 EGFR
7 Decreased viability GR00301-A 10.73 KRAS
8 Decreased viability GR00342-S-1 10.73 MTOR MAP2K7
9 Decreased viability GR00342-S-2 10.73 MTOR
10 Decreased viability GR00381-A-1 10.73 KRAS
11 Decreased viability GR00402-S-2 10.73 MTOR WNK1 MAP2K7 EGFR HRAS KRAS
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-117 10.27 KRAS
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 10.27 KRAS
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 10.27 KRAS
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 10.27 MTOR
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-193 10.27 KRAS
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 10.27 KRAS
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-22 10.27 KRAS
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 10.27 KRAS
20 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 10.27 WNK1 KRAS
21 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 10.27 WNK1 MTOR KRAS
22 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 10.27 MTOR
23 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 10.27 KRAS
24 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 10.27 WNK1
25 Decreased viability with paclitaxel GR00179-A-1 9.85 MTOR EGFR
26 Decreased viability with paclitaxel GR00179-A-2 9.85 MTOR
27 Decreased viability with paclitaxel GR00179-A-3 9.85 MTOR EGFR
28 Decreased substrate adherent cell growth GR00193-A-2 9.8 WNK1 MTOR MAP2K7 EGFR
29 Decreased substrate adherent cell growth GR00193-A-3 9.8 WNK1 MAP2K7
30 Decreased cell migration GR00055-A-1 9.71 MTOR KRAS HRAS EGFR
31 Increased cell migration GR00055-A-3 9.26 MTOR KRAS HRAS EGFR
32 Reduced mammosphere formation GR00396-S 8.92 KRAS MTOR EGFR HRAS

MGI Mouse Phenotypes related to Paronychia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.88 WNK1 KRAS MAP2K7 EGFR MTOR HRAS
2 cardiovascular system MP:0005385 9.85 HRAS WNK1 KRAS EGFR MTOR
3 mortality/aging MP:0010768 9.85 HRAS WNK1 KRAS MAP2K7 EGFR MTOR
4 endocrine/exocrine gland MP:0005379 9.83 KRAS MAP2K7 EGFR MTOR HRAS
5 nervous system MP:0003631 9.73 KRAS MAP2K7 EGFR MTOR HRAS WNK1
6 neoplasm MP:0002006 9.62 KRAS MAP2K7 EGFR HRAS
7 no phenotypic analysis MP:0003012 9.46 HRAS KRAS EGFR MTOR
8 normal MP:0002873 9.35 KRAS MAP2K7 EGFR MTOR HRAS
9 renal/urinary system MP:0005367 9.02 KRAS EGFR MTOR HRAS WNK1

Drugs & Therapeutics for Paronychia

Drugs for Paronychia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 92)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cetuximab Approved Phase 4 205923-56-4 56842117 2333
2
Fluorouracil Approved Phase 4,Phase 2 51-21-8 3385
3
Irinotecan Approved, Investigational Phase 4,Phase 2 97682-44-5, 100286-90-6 60838
4
Amorolfine Approved, Investigational Phase 4 78613-35-1
5
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
6
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
7
leucovorin Approved, Nutraceutical Phase 4,Phase 2 58-05-9 143 6006
8
Menadione Approved, Nutraceutical Phase 4 58-27-5 4055
9
Phytonadione Approved, Investigational, Nutraceutical Phase 4 84-80-0 4812 5284607
10 Antibodies Phase 4,Phase 2
11 Antibodies, Monoclonal Phase 4,Phase 2
12 Immunoglobulins Phase 4,Phase 2
13 Mitogens Phase 4,Not Applicable
14 Vitamin B Complex Phase 4
15 Vitamin K 1 Phase 4
16 Vitamins Phase 4
17 Anti-Infective Agents Phase 4,Phase 2,Not Applicable
18 Antifungal Agents Phase 4
19 Folate Nutraceutical Phase 4
20 Menaquinone Nutraceutical Phase 4
21 naphthoquinone Nutraceutical Phase 4
22 Vitamin B9 Nutraceutical Phase 4
23 Vitamin K Nutraceutical Phase 4
24
Amoxicillin Approved, Vet_approved Phase 2,Not Applicable 26787-78-0 33613
25
Ciprofloxacin Approved, Investigational Phase 2 85721-33-1 2764
26
Clindamycin Approved, Vet_approved Phase 2 18323-44-9 29029
27
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
28
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754
29
Hydroxyzine Approved Phase 2 68-88-2 3658
30
Petrolatum Approved, Investigational Phase 2 8009-03-8
31
Silver sulfadiazine Approved, Vet_approved Phase 2 22199-08-2 441244
32
Sulfadiazine Approved, Investigational, Vet_approved Phase 2 68-35-9 5215
33
Methylprednisolone Approved, Vet_approved Phase 2 83-43-2 6741
34
Prednisolone Approved, Vet_approved Phase 2 50-24-8 5755
35
Azacitidine Approved, Investigational Phase 2 320-67-2 9444
36
Decitabine Approved, Investigational Phase 2 2353-33-5 451668
37 Lycopene Approved, Investigational, Nutraceutical Phase 2 502-65-8 446925
38 Tomato Approved, Nutraceutical Phase 2
39
Butyric Acid Experimental, Investigational Phase 2 107-92-6 264
40
Camptothecin Experimental Phase 2 7689-03-4
41 Anti-Bacterial Agents Phase 2,Not Applicable
42 Antibiotics, Antitubercular Phase 2,Not Applicable
43 Anti-Inflammatory Agents Phase 2
44 Antineoplastic Agents, Phytogenic Phase 2
45 Antitubercular Agents Phase 2,Not Applicable
46 Clavulanic Acid Phase 2
47 Clindamycin palmitate Phase 2
48 Clindamycin phosphate Phase 2
49 Cortisol succinate Phase 2
50 Dermatologic Agents Phase 2

Interventional clinical trials:

(show all 14)
# Name Status NCT ID Phase Drugs
1 FOLFIRI in Combination With Cetuximab in the First-line Treatment of Metastatic Colorectal Cancer Including a Regular Dermal Prophylaxis to Prevent Acneiforme Follicular Exanthema Unknown status NCT01315990 Phase 4 FOLFIRI + Cetuximab
2 A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis Treatment Completed NCT02464826 Phase 4 Nailprotex
3 Comparison Between Long-pulsed Nd:YAG, Amorolfine and Combination Treatment in Treating Non-dermatophyte Onychomycosis Recruiting NCT02812043 Phase 4 Amorolfine
4 Afatinib Treatment for Patients With EGFR Mutation Positive NSCLC Who Are Age 70 or Older Active, not recruiting NCT02514174 Phase 4 Afatinib
5 Afatinib in EGFR+NSCLC (Recurrent or Stage IV) - Patients With Poor Performance Status (ECOG 2 or 3) Terminated NCT02695290 Phase 4 Afatinib
6 Skin Toxicity Treatment in Metastatic Colorectal Cancer (mCRC) Patients Receiving Panitumumab + Irinotecan-based Therapy Completed NCT00332163 Phase 2 Irinotecan;FOLFIRI;Pre-emptive Skin Treatment;Reactive Skin Treatment
7 Study Of Dacomitinib (PF-00299804) In Advanced NSCLC Patients (Post Chemo Or Select First Line) To Evaluate Prophylactic Intervention On Derm And GI AEs And PRO Completed NCT01465802 Phase 2 Dacomitinib;Dacomitinib;Doxycycline;Probiotic;Alclometasone cream
8 A Study of Management of Tarceva - Induced Rash in Patients With Non-Small Cell Lung Cancer. Completed NCT00531934 Phase 2 Doxycline;erlotinib [Tarceva]
9 An Efficacy and Safety Study of Decitabine in Participants With Myelodysplastic Syndrome (MDS) Completed NCT00744757 Phase 2 Decitabine
10 Panitumumab Skin Toxicity Prevention Trial Recruiting NCT03167268 Phase 2 Lycopene
11 A Trial to Evaluate the Efficacy and Safety of Two Concentrations of VBP-926 Solution for the Treatment of Chemotherapy-associated Paronychia in Cancer Patients Active, not recruiting NCT03207906 Phase 2 VBP-926
12 Preventive Effect of EGF Cream for Cutaneous Adverse Event of EGFR Inhibitors Recruiting NCT03051880 Not Applicable Repair Control EGF®;Cream without rhEGF
13 Impact of Antibiotic Treatment of Group A Streptococcal Blistering Distal Dactylitis in Children Recruiting NCT02624882 Not Applicable
14 GIOTRIF in First Line Therapy of Advanced NSCLC With EGFR-mutations Active, not recruiting NCT02047903 Afatinib

Search NIH Clinical Center for Paronychia

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: paronychia

Genetic Tests for Paronychia

Genetic tests related to Paronychia:

# Genetic test Affiliating Genes
1 Paronychia 29

Anatomical Context for Paronychia

MalaCards organs/tissues related to Paronychia:

41
Skin, Lung, T Cells, Testes

Publications for Paronychia

Articles related to Paronychia:

(show top 50) (show all 225)
# Title Authors Year
1
Topical Betaxolol for Treating Relapsing Paronychia with Pyogenic Granuloma-Like Lesions Induced by Epidermal Growth Factor Receptor Inhibitors. ( 29339238 )
2018
2
Febrile neutropenia with bacterial paronychia. ( 29531738 )
2018
3
Using a novel scoring system for paronychia related to oncologic treatments (SPOT) for assessing paronychia severity and its correlation with pain index and quality of life. ( 29894010 )
2018
4
Topical Timolol for Paronychia and Pseudopyogenic Granuloma in Patients Treated With Epidermal Growth Factor Receptor Inhibitors and Capecitabine. ( 29117285 )
2018
5
Relationship between Paronychia and Drug Concentrations of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. ( 29902802 )
2018
6
Chronic Paronychia and Onychomadesis in Pemphigus Vegetans: An Unusual Presentation in a Rare Autoimmune Disease. ( 29560011 )
2018
7
Purulent Pericarditis Due to Paronychia in a 16-Month-Old Child: A Nail-Biting Story. ( 29506451 )
2018
8
Retronychia a little-known cause of paronychia: A report of two cases in adolescent patients. ( 29479729 )
2018
9
Recurrent Paronychia as a Presenting Manifestation of Pemphigus Vulgaris: A Case Report. ( 28611998 )
2017
10
Acute and Chronic Paronychia. ( 28671378 )
2017
11
Nail Braces for Severe Paronychia Induced by Epidermal Growth Factor Receptor Inhibitors: An alternative to nail extraction. ( 28987490 )
2017
12
Primary Cutaneous CD8+ T-cell Lymphoma, an Indolent and Locally Aggressive Form Mimicking Paronychia. ( 28984695 )
2017
13
Neonatal Acute Paronychia. ( 28720045 )
2017
14
Paronychia: What You Should Know. ( 28671380 )
2017
15
Chinese Medicine Treatment for Afatinib-Induced Paronychia. ( 28948057 )
2017
16
Paronychia with Sporangium Formation Causing an Ingrown Toenail A Rare Case Report. ( 29116824 )
2017
17
Chemotherapy-associated paronychia treated with 2% povidone-iodine: a series of cases. ( 28721095 )
2017
18
Pediatric Dermatology Photoquiz: Refractory Purulent Paronychia in a Young Girl. Paronychial cutaneous leishmaniasis. ( 26758096 )
2016
19
Acute felon and paronychia: Antibiotics not necessary after surgical treatment. Prospective study of 46 patients. ( 27117023 )
2016
20
Paronychia and granulation tissue formation during treatment with isotretinoin. ( 27192525 )
2016
21
Toenail paronychia. ( 27810017 )
2016
22
Non-healing ulcerative paronychia. ( 28017401 )
2016
23
sQuiz your knowledge: chronic paronychia of the third toe. ( 27241472 )
2016
24
Periungual Abscess Caused by Citrobacter braakii in a Patient with Chronic Paronychia. ( 27489449 )
2016
25
sQUIZ your knowledge: Chronic paronychia of the third toe. ( 27789424 )
2016
26
Paronychia and onychomadesis due to pemphigus vulgaris. ( 27506502 )
2016
27
Chronic paronychia treatment: Square flap technique. ( 26946988 )
2016
28
Paronychia-like digital metastases of osteosarcoma. ( 27495265 )
2016
29
Congenital Malalignment of the Great Toenails With Acute Paronychia. ( 27396767 )
2016
30
Ungual squamous cell carcinoma mimicking a chronic paronychia: clinical, pathological and radiological correlation. ( 26632936 )
2015
31
Chemotherapy-associated paronychia treated with a dilute povidone-iodine/dimethylsulfoxide preparation. ( 26445556 )
2015
32
Evaluation of role of Candida in patients with chronic paronychia. ( 26087081 )
2015
33
HPLC-UV/DAD and ESI-MS(n) analysis of flavonoids and antioxidant activity of an Algerian medicinal plant: Paronychia argentea Lam. ( 25910047 )
2015
34
Tips to Treat the 5 Most Common Nail Disorders: Brittle Nails, Onycholysis, Paronychia, Psoriasis, Onychomycosis. ( 25828710 )
2015
35
Effective treatments for paronychia caused by oncology pharmacotherapy. ( 26596962 )
2015
36
Antibiotic Overuse and Paronychia: A Teachable Moment. ( 26569127 )
2015
37
Paronychia-like cutaneous leishmaniasis. ( 26632940 )
2015
38
Treatment and prevention of paronychia using a new combination of topicals: 30 cases report. ( 25854670 )
2015
39
Case of Fusarium paronychia successfully treated with occlusive dressing of antifungal cream. ( 24533442 )
2014
40
Management of chronic paronychia. ( 24470654 )
2014
41
Oleanane type glycosides from Paronychia anatolica subsp. balansae. ( 24321579 )
2014
42
Images in clinical medicine. Cutaneous leishmaniasis with a paronychia-like lesion. ( 25354107 )
2014
43
Clinical and cytologic features of antibiotic-resistant acute paronychia. ( 24355264 )
2014
44
Periungual Bowen disease mimicking chronic paronychia and diagnosed by dermoscopy. ( 25128126 )
2014
45
Atypical chronic sterile paronychia leading to tissue and joint space destruction in a patient with thromboangiitis obliterans. ( 23127186 )
2014
46
Chronic paronychia in a hairdresser. ( 24985481 )
2014
47
Acute and chronic paronychia of the hand. ( 24603826 )
2014
48
Paronychia-like digital cutaneous metastasis. ( 24690016 )
2014
49
Paronychia induced by the epidermal growth factor receptor inhibitor cetuximab. ( 23161875 )
2013
50
Tuberculous dactylitis presenting as paronychia with pseudopterygium and nail dystrophy. ( 22994887 )
2013

Variations for Paronychia

Expression for Paronychia

Search GEO for disease gene expression data for Paronychia.

Pathways for Paronychia

Pathways related to Paronychia according to GeneCards Suite gene sharing:

(show top 50) (show all 105)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.65 EGFR HRAS KRAS MAP2K7 MTOR WNK1
2
Show member pathways
13.53 EGFR HRAS KRAS MAP2K7 MTOR
3
Show member pathways
13.5 EGFR HRAS KRAS MAP2K7 MTOR
4
Show member pathways
13.36 EGFR HRAS KRAS MAP2K7 MTOR
5
Show member pathways
13.26 EGFR HRAS KRAS MTOR WNK1
6
Show member pathways
13.14 EGFR HRAS KRAS MAP2K7
7
Show member pathways
12.94 EGFR HRAS KRAS MTOR
8
Show member pathways
12.93 EGFR HRAS KRAS MTOR
9
Show member pathways
12.91 EGFR HRAS KRAS MAP2K7
10
Show member pathways
12.87 EGFR HRAS KRAS MTOR
11
Show member pathways
12.8 EGFR HRAS KRAS MTOR
12
Show member pathways
12.8 EGFR HRAS KRAS MAP2K7
13
Show member pathways
12.77 EGFR HRAS KRAS MTOR
14 12.73 EGFR HRAS KRAS MTOR
15
Show member pathways
12.7 HRAS KRAS MAP2K7 MTOR
16
Show member pathways
12.68 EGFR HRAS KRAS MAP2K7 MTOR
17
Show member pathways
12.67 EGFR HRAS KRAS MTOR
18 12.66 EGFR HRAS KRAS MAP2K7
19
Show member pathways
12.65 EGFR HRAS KRAS MTOR
20
Show member pathways
12.62 EGFR HRAS KRAS MTOR
21
Show member pathways
12.6 EGFR HRAS KRAS
22
Show member pathways
12.6 EGFR HRAS KRAS
23
Show member pathways
12.6 HRAS KRAS MAP2K7 MTOR
24
Show member pathways
12.55 EGFR HRAS KRAS MAP2K7
25
Show member pathways
12.54 EGFR HRAS KRAS
26
Show member pathways
12.54 EGFR HRAS MTOR
27
Show member pathways
12.52 EGFR HRAS KRAS MAP2K7 MTOR
28 12.5 EGFR HRAS KRAS
29
Show member pathways
12.48 EGFR HRAS KRAS
30
Show member pathways
12.48 HRAS KRAS MAP2K7
31
Show member pathways
12.46 HRAS KRAS MAP2K7 MTOR
32
Show member pathways
12.42 HRAS MAP2K7 MTOR
33
Show member pathways
12.42 EGFR HRAS KRAS MAP2K7 MTOR
34 12.41 EGFR HRAS KRAS MTOR
35
Show member pathways
12.39 HRAS KRAS MTOR
36
Show member pathways
12.39 EGFR HRAS KRAS MTOR
37
Show member pathways
12.36 HRAS KRAS MTOR
38
Show member pathways
12.35 HRAS KRAS MAP2K7
39
Show member pathways
12.34 HRAS KRAS MAP2K7
40
Show member pathways
12.34 EGFR HRAS KRAS
41
Show member pathways
12.33 EGFR HRAS KRAS MTOR
42
Show member pathways
12.32 HRAS KRAS MAP2K7 MTOR
43
Show member pathways
12.31 EGFR HRAS KRAS MAP2K7
44
Show member pathways
12.29 EGFR HRAS KRAS MTOR
45
Show member pathways
12.28 HRAS KRAS MTOR
46
Show member pathways
12.26 HRAS KRAS MTOR
47
Show member pathways
12.24 EGFR HRAS KRAS
48
Show member pathways
12.21 HRAS MAP2K7 MTOR
49
Show member pathways
12.21 EGFR HRAS KRAS MAP2K7 MTOR
50 12.18 EGFR HRAS KRAS MTOR

GO Terms for Paronychia

Biological processes related to Paronychia according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.93 EGFR HRAS KRAS MAP2K7 MTOR
2 phosphorylation GO:0016310 9.78 EGFR MAP2K7 MTOR WNK1
3 positive regulation of gene expression GO:0010628 9.75 HRAS KRAS MTOR
4 MAPK cascade GO:0000165 9.7 EGFR HRAS KRAS
5 protein phosphorylation GO:0006468 9.67 EGFR MAP2K7 MTOR WNK1
6 Fc-epsilon receptor signaling pathway GO:0038095 9.61 HRAS KRAS MAP2K7
7 positive regulation of epithelial cell proliferation GO:0050679 9.59 EGFR HRAS
8 positive regulation of smooth muscle cell proliferation GO:0048661 9.58 EGFR MTOR
9 protein autophosphorylation GO:0046777 9.58 EGFR MTOR WNK1
10 cellular response to amino acid stimulus GO:0071230 9.57 EGFR MTOR
11 visual learning GO:0008542 9.56 KRAS MTOR
12 positive regulation of DNA replication GO:0045740 9.55 EGFR HRAS
13 cell aging GO:0007569 9.51 HRAS MTOR
14 regulation of long-term neuronal synaptic plasticity GO:0048169 9.49 HRAS KRAS
15 response to osmotic stress GO:0006970 9.46 EGFR MAP2K7
16 positive regulation of MAP kinase activity GO:0043406 9.43 EGFR HRAS KRAS
17 epidermal growth factor receptor signaling pathway GO:0007173 9.33 EGFR HRAS KRAS
18 response to isolation stress GO:0035900 9.32 HRAS KRAS
19 ERBB2 signaling pathway GO:0038128 9.13 EGFR HRAS KRAS
20 positive regulation of protein phosphorylation GO:0001934 8.92 EGFR HRAS KRAS MTOR

Molecular functions related to Paronychia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 kinase activity GO:0016301 9.56 EGFR MAP2K7 MTOR WNK1
2 protein serine/threonine kinase activity GO:0004674 9.54 MAP2K7 MTOR WNK1
3 protein kinase activity GO:0004672 9.46 EGFR MAP2K7 MTOR WNK1
4 GDP binding GO:0019003 9.32 HRAS KRAS
5 protein kinase binding GO:0019901 9.26 EGFR MAP2K7 MTOR WNK1
6 nucleotide binding GO:0000166 8.92 EGFR HRAS KRAS MTOR

Sources for Paronychia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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