MCID: PRT031
MIFTS: 24

Parotid Disease

Categories: Oral diseases

Aliases & Classifications for Parotid Disease

MalaCards integrated aliases for Parotid Disease:

Name: Parotid Disease 12 15 17
Parotid Diseases 44 70

Classifications:



External Ids:

Disease Ontology 12 DOID:10302
MeSH 44 D010305
UMLS 70 C0030579

Summaries for Parotid Disease

MalaCards based summary : Parotid Disease, also known as parotid diseases, is related to parotitis and facial paralysis. An important gene associated with Parotid Disease is CRP (C-Reactive Protein). Affiliated tissues include bone, lymph node and breast.

Related Diseases for Parotid Disease

Diseases related to Parotid Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 241)
# Related Disease Score Top Affiliating Genes
1 parotitis 30.9 TRIM21 SSB SPINK1 KLK4 CRP CD8A
2 facial paralysis 30.2 CRP CD8A CD4
3 sialadenitis 29.9 TRIM21 SSB CD4
4 sarcoidosis 1 29.8 CRP CD8A CD4
5 panniculitis 29.7 PSMB8 CRP CD8A CD4
6 parotid gland cancer 29.4 ZNFX1 TNS4 SLC26A9
7 panophthalmitis 10.4 CRP CD4
8 epidural abscess 10.4 CRP CD4
9 pericardial tuberculosis 10.4 CRP CD4
10 urogenital tuberculosis 10.4 CRP CD4
11 meningovascular neurosyphilis 10.4 CRP CD4
12 pyomyositis 10.4 CRP CD4
13 suppurative lymphadenitis 10.4 CRP CD4
14 splenic abscess 10.4 CRP CD4
15 orbital cellulitis 10.4 CRP CD4
16 acute orbital inflammation 10.4 CRP CD4
17 neuroretinitis 10.4 CRP CD4
18 opportunistic bacterial infectious disease 10.4 CRP CD4
19 mediastinitis 10.4 CRP CD4
20 nocardiosis 10.4 CRP CD4
21 arachnoiditis 10.4 CRP CD4
22 optic papillitis 10.4 CRP CD4
23 gastrointestinal tuberculosis 10.4 CRP CD4
24 intestinal tuberculosis 10.4 CRP CD4
25 lymph node tuberculosis 10.4 CRP CD4
26 external ear disease 10.4 CRP CD4
27 otitis externa 10.4 CRP CD4
28 lymphangitis 10.4 CRP CD4
29 cork-handlers' disease 10.4 CD8A CD4
30 necrotic uveal melanoma 10.4 CD8A CD4
31 splenic tuberculosis 10.4 CRP CD4
32 cat-scratch disease 10.4 CRP CD4
33 hypopyon 10.4 CRP CD4
34 early yaws 10.4 CD8A CD4
35 tenosynovitis 10.4 CRP CD4
36 aortitis 10.3 CRP CD4
37 latent syphilis 10.3 CD8A CD4
38 tracheitis 10.3 CRP CD8A
39 type 1 diabetes mellitus 23 10.3 CD8A CD4
40 autoimmune lymphoproliferative syndrome, type iia 10.3 CD8A CD4
41 lung abscess 10.3 CRP CD4
42 parapsoriasis 10.3 CD8A CD4
43 gastroduodenitis 10.3 CD8A CD4
44 abdominal tuberculosis 10.3 CRP CD4
45 first-degree atrioventricular block 10.3 TRIM21 CRP
46 norwegian scabies 10.3 CD8A CD4
47 cervical adenitis 10.3 CRP CD4
48 second-degree atrioventricular block 10.3 TRIM21 SSB
49 lipid pneumonia 10.3 MUC1 CRP
50 skin sarcoidosis 10.3 CD8A CD4

Graphical network of the top 20 diseases related to Parotid Disease:



Diseases related to Parotid Disease

Symptoms & Phenotypes for Parotid Disease

Drugs & Therapeutics for Parotid Disease

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of Safety and Effectiveness of the FMwand Ferromagnetic Surgical System During Parotidectomy Surgery Completed NCT02291939

Search NIH Clinical Center for Parotid Disease

Cochrane evidence based reviews: parotid diseases

Genetic Tests for Parotid Disease

Anatomical Context for Parotid Disease

MalaCards organs/tissues related to Parotid Disease:

40
Bone, Lymph Node, Breast, Skin

Publications for Parotid Disease

Articles related to Parotid Disease:

(show top 50) (show all 131)
# Title Authors PMID Year
1
Benign parotid mass and facial palsy: systematic review. 61
32969265 2021
2
Long-Term Results of a Pedicled and Innervated Sternocleidomastoid Muscle Flap to Immediately Reconstruct Superficial Parotidectomy Defects. 61
32456521 2020
3
Outcomes and prognosticators in regionally recurrent cutaneous squamous cell carcinoma of the head and neck. 61
32800595 2020
4
Prospective outcomes following drainless superficial parotidectomy with sternocleidomastoid flap reconstruction. 61
33023674 2020
5
Trends in parotidectomy over 30 years in an Australian tertiary care center. 61
32618071 2020
6
Factors associated with facial weakness following surgery for benign parotid disease: a retrospective multicenter study. 61
33007165 2020
7
Salivary Carcinosarcoma: An Extremely Rare and Highly Aggressive Malignancy. 61
31291005 2020
8
Graft interposition for preventing Frey's syndrome in patients undergoing parotidectomy. 61
31578708 2019
9
Parotid incidentalomas on positron emission tomography: what is their clinical significance? 61
30614921 2019
10
The Clinical Significance of Incidental Parotid Uptake in a PET/CT Study: A Diagnostic Algorithm. 61
31989884 2019
11
Ultrasound detection of incidental diffuse parotid disease: A single-center study. 61
31269074 2019
12
Value of Visualization of the Intraparotid Facial Nerve and Parotid Duct Using a Micro Surface Coil and Three-Dimensional Reversed Fast Imaging With Steady-State Precession and Diffusion-Weighted Imaging Sequence. 61
29927823 2018
13
Buccal space malignancy in the setting of chronic sialadenitis: A report of 2 cases. 61
29493724 2018
14
Comparison of Complications in Parotid Surgery With Harmonic Scalpel Versus Cold Instruments. 61
28230591 2017
15
Thirty-Day Perioperative Outcomes in Pediatric Parotidectomy. 61
27254314 2016
16
Head and neck melanoma (excluding ocular melanoma): United Kingdom National Multidisciplinary Guidelines. 61
27841141 2016
17
Contrast-enhanced ultrasound in the evaluation of parotid gland lesions: an update of the literature. 61
27482279 2016
18
Parotid Gland Imaging. 61
26902980 2016
19
Oncocytic carcinoma of the major salivary glands: A population-based study of 278 cases. 61
26829582 2016
20
Rare Parotid Gland Diseases. 61
26902981 2016
21
Evaluation of Parotid Glands With Real-time Ultrasound Elastography in Children. 61
26903660 2016
22
Sensitivity, Specificity, and Posttest Probability of Parotid Fine-Needle Aspiration: A Systematic Review and Meta-analysis. 61
26428476 2016
23
Sinonasal and skull base pleomorphic adenoma: a case series and literature review. 61
25712714 2015
24
Idiopathic Chronic Parotitis: Imaging Findings and Sialendoscopic Response. 61
26376430 2015
25
[The effect evaluation of suction drainage to prevent fistula after superficial parotidectomy]. 61
25636298 2014
26
A comparison of parotid imaging characteristics and sialendoscopic findings in obstructive salivary disorders. 61
24932900 2014
27
Reconstructive techniques of the parotid region. 61
24705234 2014
28
Parotid abscess: a retrospective study of 14 cases at a regional hospital in Taiwan. 61
25654957 2014
29
High-frequency ultrasound in parotid gland disease. 61
24263755 2013
30
Quality of life following surgical treatment of benign parotid disease. 61
24427625 2013
31
Evaluation of superficial musculoaponeurotic system flap and fat graft outcomes for benign and malignant parotid disease. 61
23358951 2013
32
An algorithm approach to diagnosing bilateral parotid enlargement. 61
23380830 2013
33
The diagnosis and management of parotid disease. 61
23159219 2013
34
[Salivary stone in parotid gland with a cutaneous fistula]. 61
23305643 2013
35
Parotidectomy and neck dissection in the management of conjunctival melanoma: are they necessary? 61
23007927 2012
36
Wegener's granulomatosis of the major salivary glands. 61
22417113 2012
37
Parotid gland disease in childhood: diagnosis and indications for surgical intervention. 61
21715068 2012
38
Idiopathic masseter muscle hypertrophy. 61
22435002 2011
39
Primary Sjögren syndrome in a 2-year-old patient: role of the dentist in diagnosis and dental management with a 6-year follow-up. 61
21623979 2011
40
The extended indication of parotidectomy using the modified facelift incision in benign lesions: retrospective analysis of a single institution. 61
21858558 2011
41
Face-lift incision combined with sternomastoid muscular flap in parotidectomy. 61
21403992 2011
42
Comparison of facial nerve injury and recovery rates after antegrade and retrograde nerve dissection in parotid surgery for benign disease: prospective study over 4 years. 61
20554358 2011
43
Polycystic parotid disease in a male child: report of a case and review of the literature. 61
21256652 2011
44
Pathologic occult neck disease in patients with metastatic cutaneous squamous cell carcinoma to the parotid. 61
21493233 2011
45
Efficacy of conventional whole-body ¹⁸F-FDG PET/CT in the incidental findings of parotid masses. 61
20640540 2010
46
Predictors of facial palsy after surgery for benign parotid disease: multivariate analysis of 626 operations. 61
19536764 2009
47
Parotid incidentaloma identified by combined 18F-fluorodeoxyglucose whole-body positron emission tomography and computed tomography: findings at grayscale and power Doppler ultrasonography and ultrasound-guided fine-needle aspiration biopsy or core-needle biopsy. 61
19396445 2009
48
Primary squamous cell carcinoma of Stensen's duct in a patient with HIV: the role of magnetic resonance imaging and fine-needle aspiration. 61
18642319 2009
49
Elective parotidectomy in the management of advanced auricular malignancies. 61
19029866 2008
50
[Macroamylasaemia in paediatrics]. 61
19128745 2008

Variations for Parotid Disease

Expression for Parotid Disease

Search GEO for disease gene expression data for Parotid Disease.

Pathways for Parotid Disease

GO Terms for Parotid Disease

Biological processes related to Parotid Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of viral entry into host cell GO:0046598 8.62 TRIM21 CD4

Sources for Parotid Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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