MCID: PRT100
MIFTS: 21

Parotid Gland Adenoid Cystic Carcinoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Parotid Gland Adenoid Cystic Carcinoma

MalaCards integrated aliases for Parotid Gland Adenoid Cystic Carcinoma:

Name: Parotid Gland Adenoid Cystic Carcinoma 12 15 17
Adenoid Cystic Carcinoma of Parotid Gland 71

Classifications:



External Ids:

Disease Ontology 12 DOID:0050931
UMLS 71 C1335355

Summaries for Parotid Gland Adenoid Cystic Carcinoma

Disease Ontology : 12 A parotid gland cancer that is characterized by a distinctive pattern in which abnormal nests or cords of epithelial cells surround and/or infiltrate ducts or glandular structures within the affected organ.

MalaCards based summary : Parotid Gland Adenoid Cystic Carcinoma, also known as adenoid cystic carcinoma of parotid gland, is related to adenoid cystic carcinoma and intracranial hypertension, and has symptoms including pain An important gene associated with Parotid Gland Adenoid Cystic Carcinoma is CEACAM5 (CEA Cell Adhesion Molecule 5), and among its related pathways/superpathways are DNA Damage Response (only ATM dependent) and Platinum drug resistance.

Related Diseases for Parotid Gland Adenoid Cystic Carcinoma

Diseases related to Parotid Gland Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 107)
# Related Disease Score Top Affiliating Genes
1 adenoid cystic carcinoma 10.7
2 intracranial hypertension 10.2
3 rare tumor 10.2
4 cystadenocarcinoma 10.0 ERBB2 CEACAM5
5 sebaceous breast carcinoma 10.0 ERBB2 CEACAM5
6 eccrine mixed tumor of skin 10.0 ERBB2 CEACAM5
7 breast cystic hypersecretory carcinoma 10.0 ERBB2 CEACAM5
8 vulva basal cell carcinoma 10.0 ERBB2 CEACAM5
9 vulval paget's disease 10.0 ERBB2 CEACAM5
10 vulva adenocarcinoma 10.0 ERBB2 CEACAM5
11 linitis plastica 10.0 ERBB2 CEACAM5
12 esophageal adenosquamous carcinoma 10.0 ERBB2 CEACAM5
13 apocrine sweat gland neoplasm 10.0 ERBB2 CEACAM5
14 sweat gland neoplasm 10.0 ERBB2 CEACAM5
15 gastric diffuse adenocarcinoma 10.0 ERBB2 CEACAM5
16 intracystic papillary adenoma 10.0 ERBB2 CEACAM5
17 paget disease, extramammary 10.0 ERBB2 CEACAM5
18 mature teratoma 10.0 ERBB2 CEACAM5
19 sweat gland disease 10.0 ERBB2 CEACAM5
20 sweat gland cancer 10.0 ERBB2 CEACAM5
21 microinvasive gastric cancer 10.0 ERBB2 CEACAM5
22 rectum adenocarcinoma 10.0 ERBB2 CEACAM5
23 signet ring cell adenocarcinoma 10.0 ERBB2 CEACAM5
24 mixed cell type cancer 10.0 ERBB2 CEACAM5
25 tubular adenocarcinoma 9.9 ERBB2 CEACAM5
26 papillary adenocarcinoma 9.9 ERBB2 CEACAM5
27 small intestine cancer 9.9 ERBB2 CEACAM5
28 bile duct adenocarcinoma 9.9 ERBB2 CEACAM5
29 large cell carcinoma 9.9 ERBB2 CEACAM5
30 gallbladder disease 9.9 ERBB2 CEACAM5
31 breast papillomatosis 9.8 ERBB2 CDKN2A
32 fallopian tube endometrioid adenocarcinoma 9.8 ERBB2 CDKN2A
33 esophagus adenocarcinoma 9.8 ERBB2 CDKN2A
34 esophageal disease 9.8 ERBB2 CEACAM5
35 bilateral breast cancer 9.8 ERBB2 CDKN2A
36 barrett's adenocarcinoma 9.8 ERBB2 CDKN2A
37 uterine corpus cancer 9.8 ERBB2 CDKN2A
38 oropharynx cancer 9.8 ERBB2 CDKN2A
39 childhood medulloblastoma 9.8 ERBB2 CDKN2A
40 pancreatic ductal carcinoma 9.8 ERBB2 CDKN2A
41 vagina leiomyoma 9.8 CEACAM5 CDKN2A
42 vulvar eccrine porocarcinoma 9.8 CEACAM5 CDKN2A
43 vaginal tubulovillous adenoma 9.8 CEACAM5 CDKN2A
44 vaginal adenoma 9.8 CEACAM5 CDKN2A
45 pre-malignant neoplasm 9.8 ERBB2 CDKN2A
46 vaginal benign neoplasm 9.8 CEACAM5 CDKN2A
47 lymphohistiocytoid mesothelioma 9.8 CEACAM5 CDKN2A
48 endometrial adenocarcinoma 9.8 ERBB2 CDKN2A
49 gallbladder small cell carcinoma 9.8 CEACAM5 CDKN2A
50 sporadic breast cancer 9.8 ERBB2 CDKN2A

Graphical network of the top 20 diseases related to Parotid Gland Adenoid Cystic Carcinoma:



Diseases related to Parotid Gland Adenoid Cystic Carcinoma

Symptoms & Phenotypes for Parotid Gland Adenoid Cystic Carcinoma

UMLS symptoms related to Parotid Gland Adenoid Cystic Carcinoma:


pain

Drugs & Therapeutics for Parotid Gland Adenoid Cystic Carcinoma

Search Clinical Trials , NIH Clinical Center for Parotid Gland Adenoid Cystic Carcinoma

Genetic Tests for Parotid Gland Adenoid Cystic Carcinoma

Anatomical Context for Parotid Gland Adenoid Cystic Carcinoma

Publications for Parotid Gland Adenoid Cystic Carcinoma

Articles related to Parotid Gland Adenoid Cystic Carcinoma:

# Title Authors PMID Year
1
Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report. 61
29137049 2017
2
Detection of atypical metastases in recurrent adenoid cystic carcinoma of parotid gland. 61
23575100 2013
3
Adenoid cystic carcinoma of parotid gland treated with surgery and radiotherapy: long-term outcomes, QoL assessment and review of the literature. 61
22093375 2012
4
First bite syndrome as presenting symptom of parapharyngeal adenoid cystic carcinoma. 61
21272418 2011
5
Iris metastasis from adenoid cystic carcinoma of parotid gland. 61
21045673 2011
6
[Adenoid cystic carcinoma of parotid gland: case report]. 61
19472715 2008
7
Intrasellar remote metastasis from adenoid cystic carcinoma of parotid gland: case report. 61
16902261 2006
8
Hepatic resection for metastasis from adenoid cystic carcinoma of parotid gland. 61
15778528 2005
9
Adenoid cystic carcinoma of the submandibular gland with symptomatic ovarian metastases. 61
8886883 1996

Variations for Parotid Gland Adenoid Cystic Carcinoma

Cosmic variations for Parotid Gland Adenoid Cystic Carcinoma:

9
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM130791756 salivary gland,parotid,carcinoma,adenoid cystic carcinoma c.2640C>A p.G880= 20:64227445-64227445 0

Expression for Parotid Gland Adenoid Cystic Carcinoma

Search GEO for disease gene expression data for Parotid Gland Adenoid Cystic Carcinoma.

Pathways for Parotid Gland Adenoid Cystic Carcinoma

Pathways related to Parotid Gland Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.22 ERBB2 CDKN2A
2 10.82 ERBB2 CDKN2A
3 10.49 ERBB2 CDKN2A

GO Terms for Parotid Gland Adenoid Cystic Carcinoma

Cellular components related to Parotid Gland Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 basolateral plasma membrane GO:0016323 8.62 ERBB2 CEACAM5

Biological processes related to Parotid Gland Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of immature T cell proliferation in thymus GO:0033088 8.62 ERBB2 CDKN2A

Sources for Parotid Gland Adenoid Cystic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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