MCID: PRS053
MIFTS: 23

Parsonage Turner Syndrome

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Parsonage Turner Syndrome

MalaCards integrated aliases for Parsonage Turner Syndrome:

Name: Parsonage Turner Syndrome 52
Acute Brachial Neuritis 52 71
Acute Brachial Radiculitis Syndrome 52
Acute Brachial Neuritis Syndrome 52
Idiopathic Neuralgic Amyotrophy 52
Brachial Plexus Neuritis 71
Acute Shoulder Neuritis 52

Classifications:



External Ids:

UMLS 71 C0221759 C2931902

Summaries for Parsonage Turner Syndrome

NIH Rare Diseases : 52 Parsonage Turner syndrome (PTS) is characterized by the sudden onset of shoulder and upper arm pain followed by progressive (worsening over time) weakness and/or atrophy of the affected area. The pain is felt along the path of one or more nerves and often has no obvious physical cause. The network of nerves involved in this syndrome is called the brachial plexus and it controls movement and sensation in the shoulders and arms. The cause is still unknown (idiopathic). However, r esearchers believe that most cases are due to an autoimmune response following exposure to an illness or environmental factor . Suspected triggers include viral and bacterial infections, surgery, vaccinations , injury, childbirth, strenuous exercise, certain medical procedures, and various health conditions. Treatment is symptomatic and may include pain relievers, corticosteroids and physical therapy . PTS is one of two forms of neuralgic amyotrophy . The other form is hereditary and is caused by mutations in the SEPT9 gene in about 85% of cases.

MalaCards based summary : Parsonage Turner Syndrome, also known as acute brachial neuritis, is related to amyotrophy, hereditary neuralgic and brachial plexus lesion. The drugs Acetylcholine and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include b cells and kidney.

Wikipedia : 74 Parsonage-Turner syndrome, also known as acute brachial neuropathy and neuralgic amyotrophy, is a... more...

Related Diseases for Parsonage Turner Syndrome

Diseases related to Parsonage Turner Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 amyotrophy, hereditary neuralgic 11.9
2 brachial plexus lesion 11.5
3 erb's palsy 11.5
4 gonadal dysgenesis 11.2
5 turner syndrome 11.2
6 amyotrophic neuralgia 10.9
7 neuritis 10.8
8 brachial plexus neuritis 10.5
9 hepatitis e 10.5
10 neuropathy 10.5
11 radiculopathy 10.4
12 muscular atrophy 10.4
13 osteomyelitis 10.4
14 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.3
15 lyme disease 10.3
16 peripheral nervous system disease 10.3
17 herpes zoster 10.3
18 carpal tunnel syndrome 10.1
19 hand skill, relative 10.1
20 myeloma, multiple 10.1
21 reflex sympathetic dystrophy 10.1
22 aspergillosis 10.1
23 exanthem 10.1
24 inflammatory bowel disease 10.1
25 multicentric castleman disease 10.1
26 castleman disease 10.1
27 mononeuropathy 10.1
28 allergic hypersensitivity disease 10.1
29 acoustic neuroma 10.1
30 guillain-barre syndrome 10.1
31 allergic bronchopulmonary aspergillosis 10.1
32 diarrhea 10.1
33 algoneurodystrophy 10.1
34 frozen shoulder 10.1
35 hepatitis 10.1
36 sensory peripheral neuropathy 10.1
37 neurilemmoma 10.1
38 plexopathy 10.1
39 brachial plexus neuropathy 10.1
40 neuromuscular disease 10.1
41 b-cell lymphoma 10.1
42 nervous system disease 10.1
43 chickenpox 10.1
44 polymyositis 10.1
45 cytomegalovirus infection 10.1
46 hereditary neuropathies 10.1
47 paresthesia 10.1
48 pfeiffer syndrome 10.0
49 spondylosis, cervical 10.0
50 immune deficiency disease 10.0

Graphical network of the top 20 diseases related to Parsonage Turner Syndrome:



Diseases related to Parsonage Turner Syndrome

Symptoms & Phenotypes for Parsonage Turner Syndrome

Drugs & Therapeutics for Parsonage Turner Syndrome

Drugs for Parsonage Turner Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
2 Neurotransmitter Agents Phase 4
3 Acetylcholine Release Inhibitors Phase 4
4 Botulinum Toxins Phase 4
5 Cholinergic Agents Phase 4
6
Ibuprofen Approved Phase 2, Phase 3 15687-27-1 3672
7 Anti-Inflammatory Agents Phase 2, Phase 3
8 Analgesics, Non-Narcotic Phase 2, Phase 3
9 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3
10 Cyclooxygenase Inhibitors Phase 2, Phase 3
11 Antirheumatic Agents Phase 2, Phase 3
12 Analgesics Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Probe Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome Completed NCT00241215 Phase 4 Botulinum toxin serotype A
2 Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain Completed NCT02593721 Phase 2, Phase 3 Ibuprofen
3 Cervicobrachial Neuralgia and Sagital Balance of the Cervical Spine Unknown status NCT03397459
4 Longitudinal Experimental Study on ULNTT1 and Cervico-Thoracic Spine Motion Patterns Relationship Completed NCT02632357
5 The GRANVIA®-C Cervical Disc Prosthesis to Treat Symptomatic Degenerative Disc Diseases Completed NCT01518582
6 Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group Completed NCT02596815
7 Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group Completed NCT02595294
8 Neuralgic Amyotrophy: Central Reorganization and Rehabilitation After Peripheral Dysfunction Enrolling by invitation NCT03441347

Search NIH Clinical Center for Parsonage Turner Syndrome

Genetic Tests for Parsonage Turner Syndrome

Anatomical Context for Parsonage Turner Syndrome

MalaCards organs/tissues related to Parsonage Turner Syndrome:

40
B Cells, Kidney

Publications for Parsonage Turner Syndrome

Articles related to Parsonage Turner Syndrome:

(show top 50) (show all 188)
# Title Authors PMID Year
1
Neuromuscular Mimics of Entrapment Neuropathies of Upper Extremities. 61
32020820 2020
2
Bilateral Parsonage-Turner Syndrome After Initial Unilateral Presentation: A Case Report. 61
31886104 2019
3
MRI Appearances of Parsonage-Turner Syndrome. 61
31659981 2019
4
Cervical spondylotic amyotrophy: a systematic review. 61
31037421 2019
5
Neuralgic Amyotrophy in a 66-year-old Hiker: a Case Report. 61
31762709 2019
6
MR neurography in Parsonage-Turner syndrome. 61
31741594 2019
7
A rare case of pure sensitive Parsonage-Turner syndrome. 61
30729338 2019
8
Teaching Video NeuroImages: Hourglass-like fascicular constriction in Parsonage-Turner syndrome. 61
31085734 2019
9
Post-operative nerve injuries after cervical spine surgery. 61
30498911 2019
10
Brachial plexitis: an unusual presentation in sickle cell disease. 61
31723392 2019
11
Parsonage-Turner Syndrome as a Rare Extrahepatic Complication of Hepatitis E Infection. 61
31508389 2019
12
Post-operative emergence of acute brachial neuritis following posterior cervical laminectomy with fusion: A case report and review of the literature. 61
31726257 2019
13
[Parsonage-Turner syndrome: Unknown but not infrequent. Apropos of 6 cases]. 61
30929832 2019
14
Recurrent Brachial Neuritis Attacks in Presentation of B-Cell Lymphoma. 61
30560241 2018
15
[Neurologic disorders and Hepatitis E: Review of literature]. 61
30033188 2018
16
Surgical and Clinical Decision Making in Isolated Long Thoracic Nerve Palsy. 61
28975819 2018
17
Acute hepatitis E in French patients and neurological manifestations. 61
29966614 2018
18
Brachial plexitis or neuritis? MRI features of lesion distribution in Parsonage-Turner syndrome. 61
29461642 2018
19
Hepatitis E virus in neurological disorders: a case of Parsonage-Turner syndrome. 61
29685043 2018
20
Parsonage-Turner syndrome secondary to Lyme disease. 61
28549944 2018
21
Acute Shoulder Pain Followed by Shoulder Weakness and Atrophy: A Characteristic Presentation of Parsonage-Turner Syndrome. 61
28956267 2018
22
Infant brachial neuritis following a viral prodrome: a case in a 6-month old child and review of the literature. 61
28884231 2018
23
[Parsonage-Turner Syndrome - Case Report]. 61
28926848 2017
24
Parsonage-Turner syndrome in a patient with bilateral shoulder pain: A case report. 61
29255532 2017
25
The electrodiagnostic natural history of parsonage-turner syndrome. 61
28044362 2017
26
18F-FDG Uptake in Parsonage-Turner Syndrome. 61
28759527 2017
27
Management of Atraumatic Posterior Interosseous Nerve Palsy. 61
28969808 2017
28
Neuralgic Amyotrophy Attributed Incorrectly to Block-Related Injury: Understanding Errors in Clinical Reasoning. 61
28665875 2017
29
Brachial Plexus Neuritis Associated With Anti-Programmed Cell Death-1 Antibodies: Report of 2 Cases. 61
30225416 2017
30
Letter: Phrenic Nerve Palsy Secondary to Parsonage-Turner Syndrome. 61
28260176 2017
31
Parsonage-Turner syndrome due to autochthonous acute genotype 3f hepatitis E virus infection in a nonimmunocompromised 55-year-old patient. 61
28439773 2017
32
MRI bullseye sign: An indicator of peripheral nerve constriction in parsonage-turner syndrome. 61
27864992 2017
33
Atypical presentation of Parsonage-Turner syndrome confounded by surgical rotator cuff injury. 61
28739618 2017
34
Winging of the scapula diagnosed as Parsonage-Turner syndrome: a case report. 61
28853127 2017
35
Phrenic Nerve Palsy Secondary to Parsonage-Turner Syndrome: A Diagnosis Commonly Overlooked. 61
28138789 2017
36
Parsonage-Turner syndrome: A case report. 61
27079958 2017
37
Reinterpretation of Electrodiagnostic Studies and Magnetic Resonance Imaging Scans in Patients with Nontraumatic "Isolated" Anterior Interosseous Nerve Palsy. 61
27391838 2016
38
Parsonage-Turner Syndrome: A Case of Idiopathic Upper Extremity Paresis Following Middle Cranial Fossa Resection of a Vestibular Schwannoma. 61
27518132 2016
39
Brachial neuritis or Parsonage-Turner syndrome: A problem of liability. A presentation of 3 cases. 61
26948383 2016
40
Atypical Pectoralis Major Muscle Wasting in a Recreational Weight Lifter. 61
27280627 2016
41
[Infection by the hepatitis E virus as a precipitating factor of Parsonage-Turner syndrome]. 61
27270680 2016
42
Parsonage-Turner Syndrome: Clinical and Epidemiological Features From a Hand Surgeon's Perspective. 61
27390568 2016
43
High resolution neurography of the brachial plexus by 3 Tesla magnetic resonance imaging. 61
26860655 2016
44
Neurologic Disorders in Immunocompetent Patients with Autochthonous Acute Hepatitis E. 61
26490255 2015
45
[Bilateral diaphragmatic paralysis due to Parsonage-Turner syndrome]. 61
25534571 2015
46
Brachioradial pruritus in a patient with cervical disc herniation and Parsonage-Turner syndrome. 61
26131874 2015
47
Parsonage-Turner syndrome. 61
26229940 2015
48
[Parsonage-Turner syndrome following varicella-zoster virus infection]. 61
25704804 2015
49
Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy. 61
26078744 2015
50
Incidence of neuralgic amyotrophy (Parsonage Turner syndrome) in a primary care setting--a prospective cohort study. 61
26016482 2015

Variations for Parsonage Turner Syndrome

Expression for Parsonage Turner Syndrome

Search GEO for disease gene expression data for Parsonage Turner Syndrome.

Pathways for Parsonage Turner Syndrome

GO Terms for Parsonage Turner Syndrome

Sources for Parsonage Turner Syndrome

3 CDC
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48 NCI
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68 SNOMED-CT via HPO
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72 UMLS via Orphanet
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