MCID: PRS053
MIFTS: 23

Parsonage Turner Syndrome

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Parsonage Turner Syndrome

MalaCards integrated aliases for Parsonage Turner Syndrome:

Name: Parsonage Turner Syndrome 52
Acute Brachial Neuritis 52 71
Acute Brachial Radiculitis Syndrome 52
Acute Brachial Neuritis Syndrome 52
Idiopathic Neuralgic Amyotrophy 52
Brachial Plexus Neuritis 71
Acute Shoulder Neuritis 52

Classifications:



External Ids:

UMLS 71 C0221759 C2931902

Summaries for Parsonage Turner Syndrome

NIH Rare Diseases : 52 Parsonage Turner syndrome (PTS) is characterized by the sudden onset of shoulder and upper arm pain followed by progressive (worsening over time) weakness and/or atrophy of the affected area. The pain is felt along the path of one or more nerves and often has no obvious physical cause. The network of nerves involved in this syndrome is called the brachial plexus and it controls movement and sensation in the shoulders and arms. The cause is still unknown (idiopathic). However, r esearchers believe that most cases are due to an autoimmune response following exposure to an illness or environmental factor . Suspected triggers include viral and bacterial infections, surgery, vaccinations , injury, childbirth, strenuous exercise, certain medical procedures, and various health conditions. Treatment is symptomatic and may include pain relievers, corticosteroids and physical therapy . PTS is one of two forms of neuralgic amyotrophy . The other form is hereditary and is caused by mutations in the SEPT9 gene in about 85% of cases.

MalaCards based summary : Parsonage Turner Syndrome, also known as acute brachial neuritis, is related to amyotrophy, hereditary neuralgic and brachial plexus lesion. The drugs Acetylcholine and Cholinergic Agents have been mentioned in the context of this disorder. Affiliated tissues include kidney and b cells.

Wikipedia : 74 Parsonage-Turner syndrome, also known as acute brachial neuropathy and neuralgic amyotrophy, is a... more...

Related Diseases for Parsonage Turner Syndrome

Diseases related to Parsonage Turner Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 amyotrophy, hereditary neuralgic 11.9
2 brachial plexus lesion 11.5
3 erb's palsy 11.5
4 gonadal dysgenesis 11.2
5 turner syndrome 11.2
6 amyotrophic neuralgia 10.9
7 neuritis 10.8
8 brachial plexus neuritis 10.5
9 hepatitis e 10.5
10 radiculopathy 10.4
11 muscular atrophy 10.4
12 neuropathy 10.4
13 osteomyelitis 10.4
14 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.3
15 lyme disease 10.3
16 peripheral nervous system disease 10.3
17 herpes zoster 10.3
18 allergic hypersensitivity disease 10.1
19 acoustic neuroma 10.1
20 allergic bronchopulmonary aspergillosis 10.1
21 algoneurodystrophy 10.1
22 b-cell lymphoma 10.1
23 polymyositis 10.1
24 cytomegalovirus infection 10.1
25 hereditary neuropathies 10.1
26 paresthesia 10.1
27 chickenpox 10.1
28 nervous system disease 10.1
29 neuromuscular disease 10.1
30 brachial plexus neuropathy 10.1
31 plexopathy 10.1
32 neurilemmoma 10.1
33 sensory peripheral neuropathy 10.1
34 hepatitis 10.1
35 frozen shoulder 10.1
36 diarrhea 10.1
37 guillain-barre syndrome 10.1
38 mononeuropathy 10.1
39 castleman disease 10.1
40 multicentric castleman disease 10.1
41 inflammatory bowel disease 10.1
42 exanthem 10.1
43 aspergillosis 10.1
44 reflex sympathetic dystrophy 10.1
45 myeloma, multiple 10.1
46 hand skill, relative 10.1
47 carpal tunnel syndrome 10.1
48 encephalitis 10.0
49 extrapontine myelinolysis 10.0
50 influenza 10.0

Graphical network of the top 20 diseases related to Parsonage Turner Syndrome:



Diseases related to Parsonage Turner Syndrome

Symptoms & Phenotypes for Parsonage Turner Syndrome

Drugs & Therapeutics for Parsonage Turner Syndrome

Drugs for Parsonage Turner Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
2 Cholinergic Agents Phase 4
3 Neurotransmitter Agents Phase 4
4 Botulinum Toxins Phase 4
5
Ibuprofen Approved Phase 2, Phase 3 15687-27-1 3672
6 Analgesics, Non-Narcotic Phase 2, Phase 3
7 Cyclooxygenase Inhibitors Phase 2, Phase 3
8 Analgesics Phase 2, Phase 3
9 Antirheumatic Agents Phase 2, Phase 3
10 Anti-Inflammatory Agents Phase 2, Phase 3
11 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Probe Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome Completed NCT00241215 Phase 4 Botulinum toxin serotype A
2 Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain Completed NCT02593721 Phase 2, Phase 3 Ibuprofen
3 Cervicobrachial Neuralgia and Sagital Balance of the Cervical Spine Unknown status NCT03397459
4 Longitudinal Experimental Study on ULNTT1 and Cervico-Thoracic Spine Motion Patterns Relationship Completed NCT02632357
5 The GRANVIA®-C Cervical Disc Prosthesis to Treat Symptomatic Degenerative Disc Diseases Completed NCT01518582
6 Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group Completed NCT02596815
7 Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group Completed NCT02595294
8 Neuralgic Amyotrophy: Central Reorganization and Rehabilitation After Peripheral Dysfunction Enrolling by invitation NCT03441347

Search NIH Clinical Center for Parsonage Turner Syndrome

Genetic Tests for Parsonage Turner Syndrome

Anatomical Context for Parsonage Turner Syndrome

MalaCards organs/tissues related to Parsonage Turner Syndrome:

40
Kidney, B Cells

Publications for Parsonage Turner Syndrome

Articles related to Parsonage Turner Syndrome:

(show top 50) (show all 195)
# Title Authors PMID Year
1
Neuralgic amyotrophy: a paradigm shift in diagnosis and treatment. 61
32487526 2020
2
Adolescent with osteomyelitis after intramuscular administration of a vaccine: A case report. 61
32336672 2020
3
Neuralgic Amyotrophy Presenting with Multifocal Myonecrosis and Rhabdomyolysis. 61
32337110 2020
4
Screening of hepatitis E in patients presenting for acute neurological disorders. 61
32224109 2020
5
Neuromuscular Mimics of Entrapment Neuropathies of Upper Extremities. 61
32020820 2020
6
Parsonage Turner syndrome caused by Staphylococcus aureus spondylodiscitis. 61
32060112 2020
7
The magnetic resonance neurography of a Parsonage-Turner syndrome case. 61
32232206 2020
8
Bilateral Parsonage-Turner Syndrome After Initial Unilateral Presentation: A Case Report. 61
31886104 2019
9
MRI Appearances of Parsonage-Turner Syndrome. 61
31659981 2019
10
Cervical spondylotic amyotrophy: a systematic review. 61
31037421 2019
11
[Parsonage-Turner syndrome. Report of one case]. 61
32186643 2019
12
Neuralgic Amyotrophy in a 66-year-old Hiker: a Case Report. 61
31762709 2019
13
MR neurography in Parsonage-Turner syndrome. 61
31741594 2019
14
A rare case of pure sensitive Parsonage-Turner syndrome. 61
30729338 2019
15
Teaching Video NeuroImages: Hourglass-like fascicular constriction in Parsonage-Turner syndrome. 61
31085734 2019
16
Post-operative nerve injuries after cervical spine surgery. 61
30498911 2019
17
Post-operative emergence of acute brachial neuritis following posterior cervical laminectomy with fusion: A case report and review of the literature. 61
31726257 2019
18
Brachial plexitis: an unusual presentation in sickle cell disease. 61
31723392 2019
19
Parsonage-Turner Syndrome as a Rare Extrahepatic Complication of Hepatitis E Infection. 61
31508389 2019
20
[Parsonage-Turner syndrome: Unknown but not infrequent. Apropos of 6 cases]. 61
30929832 2019
21
Recurrent Brachial Neuritis Attacks in Presentation of B-Cell Lymphoma. 61
30560241 2018
22
[Neurologic disorders and Hepatitis E: Review of literature]. 61
30033188 2018
23
Surgical and Clinical Decision Making in Isolated Long Thoracic Nerve Palsy. 61
28975819 2018
24
Acute hepatitis E in French patients and neurological manifestations. 61
29966614 2018
25
Brachial plexitis or neuritis? MRI features of lesion distribution in Parsonage-Turner syndrome. 61
29461642 2018
26
Hepatitis E virus in neurological disorders: a case of Parsonage-Turner syndrome. 61
29685043 2018
27
Parsonage-Turner syndrome secondary to Lyme disease. 61
28549944 2018
28
Acute Shoulder Pain Followed by Shoulder Weakness and Atrophy: A Characteristic Presentation of Parsonage-Turner Syndrome. 61
28956267 2018
29
Infant brachial neuritis following a viral prodrome: a case in a 6-month old child and review of the literature. 61
28884231 2018
30
[Parsonage-Turner Syndrome - Case Report]. 61
28926848 2017
31
Parsonage-Turner syndrome in a patient with bilateral shoulder pain: A case report. 61
29255532 2017
32
The electrodiagnostic natural history of parsonage-turner syndrome. 61
28044362 2017
33
18F-FDG Uptake in Parsonage-Turner Syndrome. 61
28759527 2017
34
Management of Atraumatic Posterior Interosseous Nerve Palsy. 61
28969808 2017
35
Neuralgic Amyotrophy Attributed Incorrectly to Block-Related Injury: Understanding Errors in Clinical Reasoning. 61
28665875 2017
36
Brachial Plexus Neuritis Associated With Anti-Programmed Cell Death-1 Antibodies: Report of 2 Cases. 61
30225416 2017
37
Letter: Phrenic Nerve Palsy Secondary to Parsonage-Turner Syndrome. 61
28260176 2017
38
Parsonage-Turner syndrome due to autochthonous acute genotype 3f hepatitis E virus infection in a nonimmunocompromised 55-year-old patient. 61
28439773 2017
39
MRI bullseye sign: An indicator of peripheral nerve constriction in parsonage-turner syndrome. 61
27864992 2017
40
Atypical presentation of Parsonage-Turner syndrome confounded by surgical rotator cuff injury. 61
28739618 2017
41
Winging of the scapula diagnosed as Parsonage-Turner syndrome: a case report. 61
28853127 2017
42
Phrenic Nerve Palsy Secondary to Parsonage-Turner Syndrome: A Diagnosis Commonly Overlooked. 61
28138789 2017
43
Parsonage-Turner syndrome: A case report. 61
27079958 2017
44
Reinterpretation of Electrodiagnostic Studies and Magnetic Resonance Imaging Scans in Patients with Nontraumatic "Isolated" Anterior Interosseous Nerve Palsy. 61
27391838 2016
45
Parsonage-Turner Syndrome: A Case of Idiopathic Upper Extremity Paresis Following Middle Cranial Fossa Resection of a Vestibular Schwannoma. 61
27518132 2016
46
Brachial neuritis or Parsonage-Turner syndrome: A problem of liability. A presentation of 3 cases. 61
26948383 2016
47
Atypical Pectoralis Major Muscle Wasting in a Recreational Weight Lifter. 61
27280627 2016
48
[Infection by the hepatitis E virus as a precipitating factor of Parsonage-Turner syndrome]. 61
27270680 2016
49
Parsonage-Turner Syndrome: Clinical and Epidemiological Features From a Hand Surgeon's Perspective. 61
27390568 2016
50
High resolution neurography of the brachial plexus by 3 Tesla magnetic resonance imaging. 61
26860655 2016

Variations for Parsonage Turner Syndrome

Expression for Parsonage Turner Syndrome

Search GEO for disease gene expression data for Parsonage Turner Syndrome.

Pathways for Parsonage Turner Syndrome

GO Terms for Parsonage Turner Syndrome

Sources for Parsonage Turner Syndrome

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68 SNOMED-CT via HPO
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72 UMLS via Orphanet
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