MCID: PRT001
MIFTS: 21

Partial Fetal Alcohol Syndrome

Categories: Fetal diseases, Mental diseases

Aliases & Classifications for Partial Fetal Alcohol Syndrome

MalaCards integrated aliases for Partial Fetal Alcohol Syndrome:

Name: Partial Fetal Alcohol Syndrome 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:0050666
UMLS 70 C3661483

Summaries for Partial Fetal Alcohol Syndrome

Disease Ontology : 12 A fetal alcohol spectrum disorder that results in most, but not all, of the growth deficiency and/or craniofacial features of fetal alcohol syndrome including central nervous system dysfunction due to prenatal alcohol exposure.

MalaCards based summary : Partial Fetal Alcohol Syndrome is related to alcohol-related birth defect and fetal alcohol syndrome. An important gene associated with Partial Fetal Alcohol Syndrome is GMDS (GDP-Mannose 4,6-Dehydratase). Affiliated tissues include eye and brain, and related phenotype is behavior/neurological.

Related Diseases for Partial Fetal Alcohol Syndrome

Diseases related to Partial Fetal Alcohol Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 5, show less)
# Related Disease Score Top Affiliating Genes
1 alcohol-related birth defect 30.0 NTNG2 NTNG1 ACER3
2 fetal alcohol syndrome 11.3
3 fetal alcohol spectrum disorder 11.2
4 agenesis of corpus callosum, cardiac, ocular, and genital syndrome 10.0
5 st. louis encephalitis 9.8 NTNG2 NTNG1

Graphical network of the top 20 diseases related to Partial Fetal Alcohol Syndrome:



Diseases related to Partial Fetal Alcohol Syndrome

Symptoms & Phenotypes for Partial Fetal Alcohol Syndrome

MGI Mouse Phenotypes related to Partial Fetal Alcohol Syndrome:

46 (showing 1, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.17 ACER3 FEZF2 NEUROD2 NEUROG2 NOVA1 NTNG2

Drugs & Therapeutics for Partial Fetal Alcohol Syndrome

Search Clinical Trials , NIH Clinical Center for Partial Fetal Alcohol Syndrome

Genetic Tests for Partial Fetal Alcohol Syndrome

Anatomical Context for Partial Fetal Alcohol Syndrome

MalaCards organs/tissues related to Partial Fetal Alcohol Syndrome:

40
Eye, Brain

Publications for Partial Fetal Alcohol Syndrome

Articles related to Partial Fetal Alcohol Syndrome:

(showing 49, show less)
# Title Authors PMID Year
1
Altered Resting-State Neural Oscillations and Spectral Power in Children with Fetal Alcohol Spectrum Disorder. 61
33164218 2021
2
[Fetal alcohol spectrum disorders in adults]. 61
33104818 2020
3
Incontinence in persons with fetal alcohol spectrum disorders: a polish cohort. 61
32222270 2020
4
Fetal alcohol spectrum disorder among pre-adopted and foster children. 61
32493264 2020
5
Radiological Findings on Structural Magnetic Resonance Imaging in Fetal Alcohol Spectrum Disorders and Healthy Controls. 61
31840819 2020
6
Fetal Alcohol Spectrum Disorders in a Pacific Southwest City: Maternal and Child Characteristics. 61
31688971 2019
7
Are Low-to-Moderate Average Alcohol Consumption and Isolated Episodes of Binge Drinking in Early Pregnancy Associated with Facial Features Related to Fetal Alcohol Syndrome in 5-Year-Old Children? 61
30977899 2019
8
An investigation of intra-individual variability in children with fetal alcohol spectrum disorder (FASD). 61
28301980 2018
9
Challenges of diagnosing fetal alcohol spectrum disorders in foster and adopted children. 61
29316477 2018
10
Prevalence of Fetal Alcohol Spectrum Disorders in 4 US Communities. 61
29411031 2018
11
Twin study confirms virtually identical prenatal alcohol exposures can lead to markedly different fetal alcohol spectrum disorder outcomes-fetal genetics influences fetal vulnerability. 61
33364429 2018
12
[Formula: see text]Social perception in children with fetal alcohol spectrum disorder. 61
27829119 2017
13
Nocturnal incontinence in children with fetal alcohol spectrum disorders (FASD) in a South African cohort. 61
28381366 2017
14
Profile of children diagnosed with a fetal alcohol spectrum disorder: A retrospective chart review. 61
28334461 2017
15
Differential Recruitment of Brain Regions During Response Inhibition in Children Prenatally Exposed to Alcohol. 61
28075019 2017
16
Comparison of the FASD 4-Digit Code and Hoyme et al. 2016 FASD diagnostic guidelines. 61
33409370 2017
17
Cortical miscommunication after prenatal exposure to alcohol. 61
27491551 2016
18
What we know of the central auditory disorders in children exposed to alcohol during pregnancy? Systematic review. 61
27849248 2016
19
Updated Clinical Guidelines for Diagnosing Fetal Alcohol Spectrum Disorders. 61
27464676 2016
20
Worldwide Prevalence of Fetal Alcohol Spectrum Disorders: A Systematic Literature Review Including Meta-Analysis. 61
26727519 2016
21
Magnetic resonance imaging (MRI) findings among children with fetal alcohol syndrome (FAS), partial fetal alcohol syndrome (pFAS) and alcohol related neurodevelopmental disorders (ARND). 61
29688653 2016
22
Prevalence and characteristics of fetal alcohol syndrome and partial fetal alcohol syndrome in a Rocky Mountain Region City. 61
26321671 2015
23
Ethanol-related alterations in gene expression patterns in the developing murine hippocampus. 61
26063602 2015
24
Prevalence of fetal alcohol syndrome in a population-based sample of children living in remote Australia: the Lililwan Project. 61
25594247 2015
25
Verbal learning and memory impairment in children with fetal alcohol spectrum disorders. 61
25833031 2015
26
Misdiagnosis and missed diagnoses in foster and adopted children with prenatal alcohol exposure. 61
25583914 2015
27
Parietal dysfunction during number processing in children with fetal alcohol spectrum disorders. 61
26199871 2015
28
Differences in cortico-striatal-cerebellar activation during working memory in syndromal and nonsyndromal children with prenatal alcohol exposure. 61
22451272 2013
29
Approaching the prevalence of the full spectrum of fetal alcohol spectrum disorders in a South African population-based study. 61
23241076 2013
30
Prevalence of fetal alcohol syndrome and maternal characteristics in a sample of schoolchildren from a rural province of Croatia. 61
23591786 2013
31
Alcohol use in pregnancy: insights in screening and intervention for the clinician. 61
23314712 2013
32
Effects of heavy prenatal alcohol exposure and iron deficiency anemia on child growth and body composition through age 9 years. 61
22897691 2012
33
Maternal risk factors predicting child physical characteristics and dysmorphology in fetal alcohol syndrome and partial fetal alcohol syndrome. 61
21658862 2011
34
Sensory processing and adaptive behavior deficits of children across the fetal alcohol spectrum disorder continuum. 61
20374212 2010
35
Population differences in dysmorphic features among children with fetal alcohol spectrum disorders. 61
20431397 2010
36
FAS prevalence in a sample of urban schoolchildren in Croatia. 61
19922788 2010
37
Oculomotor control in children with fetal alcohol spectrum disorders assessed using a mobile eye-tracking laboratory. 61
19302166 2009
38
Neuropsychological study of FASD in a sample of American Indian children: processing simple versus complex information. 61
18828799 2008
39
Maternal risk factors for fetal alcohol syndrome and partial fetal alcohol syndrome in South Africa: a third study. 61
18336634 2008
40
The epidemiology of fetal alcohol syndrome and partial FAS in a South African community. 61
17127017 2007
41
Fetal alcohol spectrum disorders: a practical clinical approach to diagnosis. 61
16962173 2007
42
Fetal alcohol spectrum disorders in Finland: clinical delineation of 77 older children and adolescents. 61
16353236 2006
43
The neurodevelopmental consequences of prenatal alcohol exposure. 61
16084479 2005
44
A practical clinical approach to diagnosis of fetal alcohol spectrum disorders: clarification of the 1996 institute of medicine criteria. 61
15629980 2005
45
Fetal alcohol spectrum disorder and ADHD: diagnostic implications and therapeutic consequences. 61
19810932 2003
46
The subtle facial signs of prenatal exposure to alcohol: an anthropometric approach. 61
11487746 2001
47
Effectiveness of methylphenidate in Native American children with fetal alcohol syndrome and attention deficit/hyperactivity disorder: a controlled pilot study. 61
9639078 1998
48
Prenatal effects of alcohol. 61
6386408 1984
49
Prevention of fetal alcohol effects. An antenatal program for early detection of pregnancies at risk. 61
6868968 1983

Variations for Partial Fetal Alcohol Syndrome

Expression for Partial Fetal Alcohol Syndrome

Search GEO for disease gene expression data for Partial Fetal Alcohol Syndrome.

Pathways for Partial Fetal Alcohol Syndrome

GO Terms for Partial Fetal Alcohol Syndrome

Cellular components related to Partial Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

(showing 5, show less)
# Name GO ID Score Top Affiliating Genes
1 glutamatergic synapse GO:0098978 9.43 SLITRK2 NTNG2 NTNG1
2 Schaffer collateral - CA1 synapse GO:0098685 9.32 NTNG2 NTNG1
3 anchored component of plasma membrane GO:0046658 9.16 NTNG2 NTNG1
4 laminin complex GO:0043256 8.96 NTNG2 NTNG1
5 anchored component of presynaptic active zone membrane GO:0099029 8.62 NTNG2 NTNG1

Biological processes related to Partial Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

(showing 15, show less)
# Name GO ID Score Top Affiliating Genes
1 cell differentiation GO:0030154 9.8 NTNG2 NTNG1 NEUROG2 NEUROD2 FEZF2
2 multicellular organism development GO:0007275 9.63 ZNF875 NTNG2 NTNG1 NEUROG2 NEUROD2 FEZF2
3 positive regulation of neuron differentiation GO:0045666 9.55 NEUROD2 FEZF2
4 locomotory behavior GO:0007626 9.54 NOVA1 FEZF2
5 modulation of chemical synaptic transmission GO:0050804 9.52 NTNG2 NTNG1
6 substrate adhesion-dependent cell spreading GO:0034446 9.51 NTNG2 NTNG1
7 axonogenesis GO:0007409 9.5 SLITRK2 NTNG2 NTNG1
8 regulation of neuron projection development GO:0010975 9.49 NTNG2 NTNG1
9 tissue development GO:0009888 9.48 NTNG2 NTNG1
10 regulation of presynapse assembly GO:1905606 9.46 SLITRK2 NTNG2
11 regulation of neuron migration GO:2001222 9.43 NTNG2 NTNG1
12 basement membrane assembly GO:0070831 9.37 NTNG2 NTNG1
13 nervous system development GO:0007399 9.35 NTNG2 NTNG1 NEUROG2 NEUROD2 FEZF2
14 regulation of neuron projection arborization GO:0150011 9.26 NTNG2 NTNG1
15 synaptic membrane adhesion GO:0099560 8.8 SLITRK2 NTNG2 NTNG1

Molecular functions related to Partial Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 E-box binding GO:0070888 8.62 NEUROG2 NEUROD2

Sources for Partial Fetal Alcohol Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....