MCID: PRT006
MIFTS: 20

Partial Motor Epilepsy

Categories: Neuronal diseases

Aliases & Classifications for Partial Motor Epilepsy

MalaCards integrated aliases for Partial Motor Epilepsy:

Name: Partial Motor Epilepsy 12 15
Epilepsy, Partial, Motor 44 73
Epilepsy, Focal Motor 12
Focal Motor Seizure 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3327
MeSH 44 D020938
NCIt 50 C50847
UMLS 73 C0016399

Summaries for Partial Motor Epilepsy

MalaCards based summary : Partial Motor Epilepsy, also known as epilepsy, partial, motor, is related to cortical blindness and hemifacial spasm, and has symptoms including seizures and non-epileptic convulsion. An important gene associated with Partial Motor Epilepsy is EIF2B5 (Eukaryotic Translation Initiation Factor 2B Subunit Epsilon). The drugs Clobazam and Clonazepam have been mentioned in the context of this disorder.

Related Diseases for Partial Motor Epilepsy

Diseases related to Partial Motor Epilepsy via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 cortical blindness 9.8
2 hemifacial spasm 9.8
3 epilepsy 9.7
4 bone epithelioid hemangioma 9.5 F3 SMUG1
5 femoral neuropathy 9.4 F3 SMUG1
6 lemierre's syndrome 9.3 F3 SMUG1
7 endocardium disease 9.2 F3 SMUG1
8 coronary artery anomaly 9.0 F3 SMUG1

Graphical network of the top 20 diseases related to Partial Motor Epilepsy:



Diseases related to Partial Motor Epilepsy

Symptoms & Phenotypes for Partial Motor Epilepsy

UMLS symptoms related to Partial Motor Epilepsy:


seizures, non-epileptic convulsion

Drugs & Therapeutics for Partial Motor Epilepsy

Drugs for Partial Motor Epilepsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clobazam Approved, Illicit Phase 3 22316-47-8 2789
2
Clonazepam Approved, Illicit Phase 3 1622-61-3 2802
3
Lorazepam Approved Phase 3 846-49-1 3958
4 Neurotransmitter Agents Phase 3,Not Applicable
5 Anti-Anxiety Agents Phase 3
6 Anticonvulsants Phase 3
7 Antiemetics Phase 3
8 Autonomic Agents Phase 3
9 Central Nervous System Depressants Phase 3
10 GABA Agents Phase 3
11 GABA Modulators Phase 3
12 Gastrointestinal Agents Phase 3
13 Hypnotics and Sedatives Phase 3
14 Peripheral Nervous System Agents Phase 3
15 Psychotropic Drugs Phase 3
16 Tranquilizing Agents Phase 3
17
Glycerol Approved, Investigational Phase 2 56-81-5 753
18 Protective Agents Phase 2
19
Caffeine Approved, Nutraceutical Not Applicable 58-08-2 2519
20 Central Nervous System Stimulants Not Applicable
21 Phosphodiesterase Inhibitors Not Applicable
22 Purinergic P1 Receptor Antagonists Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 An Open-Label Extension Study of the Safety and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures Completed NCT00744731 Phase 3 placebo;carisbamate
2 A Study of the Effectiveness, Safety, and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures. Completed NCT00740623 Phase 3 Carisbamate;placebo;Carisbamate
3 Effectiveness and Safety Study for RWJ-333369 as Adjunctive Therapy in Korean and Japanese Patients With Partial Onset Seizures Terminated NCT00697762 Phase 3 RWJ-333369;RWJ-333369;Placebo
4 Clobazam Use in Epilepsia Partialis Continua - Pilot Study Terminated NCT02134366 Phase 3 Clobazam;Clonazepam;Lorazepam
5 Phase 2 Study of Triheptanoin (UX007) for the Treatment of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS) Completed NCT01993186 Phase 2 UX007 (triheptanoin);Placebo Oil
6 A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures Active, not recruiting NCT01866111 Phase 2 YKP3089;Placebo
7 Detecting PNES With Single-channel sEMG Enrolling by invitation NCT03313362 Not Applicable

Search NIH Clinical Center for Partial Motor Epilepsy

Cochrane evidence based reviews: epilepsy, partial, motor

Genetic Tests for Partial Motor Epilepsy

Anatomical Context for Partial Motor Epilepsy

Publications for Partial Motor Epilepsy

Articles related to Partial Motor Epilepsy:

# Title Authors Year
1
Partial motor epilepsy with "negative myoclonus". ( 1898721 )
1991

Variations for Partial Motor Epilepsy

Expression for Partial Motor Epilepsy

Search GEO for disease gene expression data for Partial Motor Epilepsy.

Pathways for Partial Motor Epilepsy

GO Terms for Partial Motor Epilepsy

Sources for Partial Motor Epilepsy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....