MCID: PTL003
MIFTS: 36

Patellar Tendinitis

Categories: Muscle diseases

Aliases & Classifications for Patellar Tendinitis

MalaCards integrated aliases for Patellar Tendinitis:

Name: Patellar Tendinitis 12 15
Patellar Tendonitis 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10471
ICD10 33 M76.5 M76.50
ICD9CM 35 726.64
SNOMED-CT 68 37785001
UMLS 73 C0158317

Summaries for Patellar Tendinitis

MalaCards based summary : Patellar Tendinitis, also known as patellar tendonitis, is related to spastic ataxia, charlevoix-saguenay type and sinding-larsen-johansson disease. An important gene associated with Patellar Tendinitis is SPAG5 (Sperm Associated Antigen 5), and among its related pathways/superpathways are Development Endothelin-1/EDNRA signaling and Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways. The drugs Acetaminophen and Peripheral Nervous System Agents have been mentioned in the context of this disorder. Affiliated tissues include bone, and related phenotypes are cellular and growth/size/body region

Wikipedia : 76 Patellar tendinitis (patellar tendinopathy, also known as jumper''s knee), is a relatively common cause... more...

Related Diseases for Patellar Tendinitis

Diseases related to Patellar Tendinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 spastic ataxia, charlevoix-saguenay type 11.2
2 sinding-larsen-johansson disease 11.2
3 tendinitis 10.8
4 tendinopathy 10.6
5 tendinosis 10.4
6 giant cell tumor 10.3
7 anterior cruciate ligament tears 10.3
8 cerebral palsy 10.2
9 sarcoma 10.2
10 osgood-schlatter's disease 10.2
11 systemic lupus erythematosus 10.1
12 rheumatoid arthritis 10.1
13 brittle bone disorder 10.1
14 arthritis 10.1
15 gout 10.1
16 ehlers-danlos syndrome 10.1
17 enthesopathy 10.1
18 lupus erythematosus 10.1
19 osteochondroma 10.1
20 arteritic anterior ischemic optic neuropathy 10.0 NOS3 MAPK14
21 spondyloarthropathy 1 10.0
22 lipomatosis, multiple 10.0
23 arthrogryposis, distal, type 2a 10.0
24 insulin-like growth factor i 10.0
25 arts syndrome 10.0
26 reflex sympathetic dystrophy 10.0
27 muscle hypertrophy 10.0
28 diabetic foot ulcers 10.0
29 pseudoarthrosis 10.0
30 spinal muscular atrophy 10.0
31 pleomorphic lipoma 10.0
32 spastic diplegia 10.0
33 lyme disease 10.0
34 secondary hyperparathyroidism of renal origin 10.0
35 hyperparathyroidism 10.0
36 algoneurodystrophy 10.0
37 frozen shoulder 10.0
38 patellofemoral pain syndrome 10.0
39 glomus tumor 10.0
40 relapsing polychondritis 10.0
41 bursitis 10.0
42 pyoderma 10.0
43 clear cell sarcoma 10.0
44 spindle cell sarcoma 10.0
45 radiculopathy 10.0
46 spondylitis 10.0
47 muscular atrophy 10.0
48 pyoderma gangrenosum 10.0
49 distal hereditary motor neuropathies 10.0
50 mycobacterium fortuitum 10.0

Graphical network of the top 20 diseases related to Patellar Tendinitis:



Diseases related to Patellar Tendinitis

Symptoms & Phenotypes for Patellar Tendinitis

MGI Mouse Phenotypes related to Patellar Tendinitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.73 DIABLO MAPK14 NOS3 PTBP1 PTBP2 VEGFA
2 growth/size/body region MP:0005378 9.63 DIABLO MAPK14 NOS3 PTBP1 PTBP2 VEGFA
3 normal MP:0002873 9.35 DIABLO MAPK14 NOS3 SPAG5 VEGFA
4 respiratory system MP:0005388 8.92 MAPK14 NOS3 PTBP2 VEGFA

Drugs & Therapeutics for Patellar Tendinitis

Drugs for Patellar Tendinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetaminophen Approved Phase 4 103-90-2 1983
2 Peripheral Nervous System Agents Phase 4,Phase 2
3 Antipyretics Phase 4
4 Analgesics Phase 4
5 Analgesics, Non-Narcotic Phase 4
6
Tetracaine Approved, Vet_approved Phase 2 94-24-6 5411
7
Lidocaine Approved, Vet_approved Phase 2 137-58-6 3676
8 Diuretics, Potassium Sparing Phase 2
9 Anesthetics, Local Phase 2
10 Anti-Arrhythmia Agents Phase 2
11 Sodium Channel Blockers Phase 2
12 Anesthetics Phase 2
13 Central Nervous System Depressants Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Close Kinect Chain Exercise With Kinesio Taping in the Management of Patellofemoral Pain Syndrome Unknown status NCT02241148 Phase 4 Acetaminophen 500mg
2 Study Evaluating a Heated Lidocaine and Tetracaine Topical Patch in the Treatment of Patients With Patellar Tendinopathy Completed NCT01111773 Phase 2 Heated Lidocaine and Tetracaine Patch
3 Platelet-Rich Plasma Therapy for Patellar Tendinopathy Recruiting NCT03136965 Phase 2
4 Effect of Distal Needling on Knee Pain Using Acupuncture Techniques Unknown status NCT01612663 Not Applicable
5 The Acute Effect of Isometric Versus Isotonic Resistance Exercise in Patients With Patellar Tendinopathy Completed NCT03528746 Not Applicable
6 The Effect of Infrapatellar Strap Treatment on Pain Extent and Athletic Measures in Young Athletes Completed NCT01460004 Not Applicable
7 Time Difference Between Onsets of Lateral And Medial Hamstring Muscles During Gait in Patients With Patellofemoral Pain. Completed NCT03392688 Not Applicable
8 Platelet Rich Plasma Versus Placebo for the Treatment of Greater Trochanteric Pain Syndrome (HiPPO Trial) Recruiting NCT03479190 Not Applicable
9 Continued Activity During Rehabilitation in Patients With Patellar Tendinopathy Recruiting NCT03694730 Not Applicable

Search NIH Clinical Center for Patellar Tendinitis

Genetic Tests for Patellar Tendinitis

Anatomical Context for Patellar Tendinitis

MalaCards organs/tissues related to Patellar Tendinitis:

41
Bone

Publications for Patellar Tendinitis

Articles related to Patellar Tendinitis:

(show all 39)
# Title Authors Year
1
Editorial Commentary: Arthroscopy Is Preferred Over Open Surgery for Patellar Tendonitis. ( 26652150 )
2015
2
Progression of patellar tendinitis following treatment with platelet-rich plasma: case reports. ( 23728418 )
2013
3
Intratendinous gouty tophus mimics patellar tendonitis in an athlete. ( 22457228 )
2013
4
Patellar tendonitis. ( 21691492 )
2011
5
Intratendinous tophaceous gout imitating patellar tendonitis in an athletic man. ( 21410111 )
2011
6
Clinical signs and anatomical correlation of patellar tendinitis. ( 20924486 )
2010
7
Arthroscopic excision of distal pole of patella for refractory patellar tendinitis. ( 19634846 )
2009
8
Patellar tendonitis and patellar dislocations. ( 15544827 )
2004
9
Kinematics of cycling in relation to anterior knee pain and patellar tendinitis. ( 12875315 )
2003
10
Is impingement the cause of jumper's knee? Dynamic and static magnetic resonance imaging of patellar tendinitis in an open-configuration system. ( 12016080 )
2002
11
Evidence of abnormal anteroposterior patellar tilt in patients with patellar tendinitis with use of a new radiographic measurement. ( 12016081 )
2002
12
Intrinsic risk factors for the development of patellar tendinitis in an athletic population. A two-year prospective study. ( 11292044 )
2001
13
Surgical aspects of patellar tendonitis: technique and results. ( 11216719 )
2001
14
Patellar tendinitis: the significance of magnetic resonance imaging findings. ( 10352771 )
1999
15
Patellar tendonitis and anterior knee pain. ( 10323501 )
1999
16
Patellar tendinitis: the significance of magnetic resonance imaging findings. ( 10569375 )
1999
17
Operative treatment and arthroscopic findings in chronic patellar tendinitis. ( 9848595 )
1998
18
Recalcitrant patellar tendinitis. Magnetic resonance imaging, histologic evaluation, and surgical treatment. ( 9079177 )
1997
19
Knee joint dynamics predict patellar tendinitis in elite volleyball players. ( 8883692 )
1996
20
Surgical intervention and rehabilitation of chronic patellar tendinitis. ( 16558376 )
1996
21
Magnetic resonance imaging of patellar tendonitis. ( 8636185 )
1996
22
The correlation of bone scintigraphy and histological findings in patellar tendinitis. ( 8692491 )
1996
23
Patellar tendinitis--a case report of elongation and ossification of the inferior pole of the patella. ( 8581575 )
1995
24
Correlation of MR imaging and pathologic findings in athletes undergoing surgery for chronic patellar tendinitis. ( 7785569 )
1995
25
Patellar tendinitis: MR imaging features, with suggested pathogenesis and proposed classification. ( 7480766 )
1995
26
Patellar tendonitis: clinical and literature review. ( 7553016 )
1995
27
Surgical treatment of chronic patellar tendinitis in a collegiate football player. ( 16558360 )
1995
28
Surgical treatment of patellar tendinitis. ( 8536009 )
1993
29
Patellar tendinitis in the recreational athlete. ( 1461820 )
1992
30
MR imaging of patellar tendinitis. ( 1509078 )
1992
31
Ultrasound, computed tomography and magnetic resonance imaging in patellar tendinitis. ( 1999074 )
1991
32
Patellar tendinitis ('jumper's knee'). ( 2775029 )
1989
33
Evaluation of eccentric exercise in treatment of patellar tendinitis. ( 2919192 )
1989
34
Computed tomography and ultrasound imaging of jumper's knee-patellar tendinitis. ( 3281780 )
1988
35
Magnetic resonance images of chronic patellar tendinitis. ( 3358133 )
1988
36
The use of thermography for the diagnosis and management of patellar tendinitis. ( 18797007 )
1987
37
Bone scintigraphic findings in patellar tendonitis. ( 3668667 )
1987
38
Patellar tendinitis: pathology and results of treatment. ( 7090767 )
1982
39
Patellar tendinitis (jumper's knee). ( 736196 )
1978

Variations for Patellar Tendinitis

Expression for Patellar Tendinitis

Search GEO for disease gene expression data for Patellar Tendinitis.

Pathways for Patellar Tendinitis

Pathways related to Patellar Tendinitis according to GeneCards Suite gene sharing:

(show all 20)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.31 DIABLO MAPK14 VEGFA
2
Show member pathways
12.28 MAPK14 NOS3 VEGFA
3
Show member pathways
12.18 MAPK14 NOS3 VEGFA
4
Show member pathways
11.95 MAPK14 NOS3 VEGFA
5
Show member pathways
11.89 MAPK14 NOS3 VEGFA
6
Show member pathways
11.69 MAPK14 NOS3 VEGFA
7 11.59 NOS3 VEGFA
8 11.55 MAPK14 NOS3
9 11.54 NOS3 SPAG5
10
Show member pathways
11.53 NOS3 VEGFA
11 11.47 MAPK14 NOS3 VEGFA
12 11.36 MAPK14 NOS3
13 11.24 NOS3 VEGFA
14 11.2 MAPK14 VEGFA
15 11.15 MAPK14 VEGFA
16 11.13 MAPK14 NOS3 VEGFA
17
Show member pathways
11.11 DIABLO MAPK14
18 11.09 MAPK14 NOS3
19 10.97 DIABLO MAPK14
20 10.18 MAPK14 NOS3 VEGFA

GO Terms for Patellar Tendinitis

Biological processes related to Patellar Tendinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.58 MAPK14 NOS3 VEGFA
2 lung development GO:0030324 9.43 NOS3 VEGFA
3 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.37 MAPK14 VEGFA
4 angiogenesis GO:0001525 9.33 MAPK14 NOS3 VEGFA
5 lipopolysaccharide-mediated signaling pathway GO:0031663 9.32 MAPK14 NOS3
6 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.26 MAPK14 VEGFA
7 negative regulation of RNA splicing GO:0033119 8.96 PTBP1 PTBP2
8 positive regulation of blood vessel endothelial cell migration GO:0043536 8.8 MAPK14 NOS3 VEGFA

Sources for Patellar Tendinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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