PET
MCID: PTL001
MIFTS: 31

Patulous Eustachian Tube (PET)

Categories: Ear diseases, Oral diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Patulous Eustachian Tube

MalaCards integrated aliases for Patulous Eustachian Tube:

Name: Patulous Eustachian Tube 12 54 15 74
Pet 54

Classifications:



External Ids:

Disease Ontology 12 DOID:12358
ICD9CM 36 381.7
SNOMED-CT 69 30280005
ICD10 34 H69.0 H69.00
UMLS 74 C0155434

Summaries for Patulous Eustachian Tube

NIH Rare Diseases : 54 Patulous eustachian tube is a benign but symptomatically troubling condition in which the eustachian tube stays open most of the time. The eustachian tube is the tube that runs between the middle ear and throat and regulates the ear pressure around the ear drum. Under normal circumstances, it remains closed most of the time, opening only on occasion to equalize air pressure between the middle ear and the exterior environment. Major symptoms include distorted autophony (hearing one's own voice or breathing), echoing which may interfere with speech production, wave-like sounds, and a sensation of fullness in the ear. In severe cases, vertigo and hearing loss may occur. Over time, individuals with patulous eustachian tube may develop serious and even extreme responses to the abnormal sounds and other findings. In most cases, the cause of patulous eustachian tube is unknown. Weight loss and pregnancy may be predisposing factors. Neurologic disorders that cause muscle atrophy such as stroke, multiple sclerosis, and motor neuron disease have been implicated in some cases of patulous eustachian tube. Other cases may be associated with medications such as oral contraceptives or diuretics. Other predisposing factors include fatigue, stress, anxiety, exercise, and temporomandibular joint syndrome. Many treatments have been proposed, however none have shown consistent effectiveness.

MalaCards based summary : Patulous Eustachian Tube, also known as pet, is related to intracranial hypotension and spontaneous intracranial hypotension. An important gene associated with Patulous Eustachian Tube is PGRMC1 (Progesterone Receptor Membrane Component 1). The drugs Triamcinolone and Triamcinolone hexacetonide have been mentioned in the context of this disorder. Affiliated tissues include prostate, brain and breast.

Disease Ontology : 12 A eustachian tube disorder with a wider eustachian tube which allows a larger bolus of bacteria-laden material from the nasopharynx during an infection to enter the middle ear, causing a more fulminant infection.

Wikipedia : 77 Patulous Eustachian tube (PET) is the name of a physical disorder where the Eustachian tube, which is... more...

Related Diseases for Patulous Eustachian Tube

Diseases related to Patulous Eustachian Tube via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 intracranial hypotension 10.5
2 spontaneous intracranial hypotension 10.5
3 amyotrophic lateral sclerosis 1 10.4
4 lateral sclerosis 10.4
5 cleft palate, isolated 10.2
6 otitis media 10.2
7 trigeminal neuralgia 10.2
8 anorexia nervosa 10.2
9 nasopharyngeal carcinoma 10.2
10 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.2
11 sensorineural hearing loss 10.2
12 relapsing polychondritis 10.2
13 middle ear disease 10.2

Graphical network of the top 20 diseases related to Patulous Eustachian Tube:



Diseases related to Patulous Eustachian Tube

Symptoms & Phenotypes for Patulous Eustachian Tube

Drugs & Therapeutics for Patulous Eustachian Tube

Drugs for Patulous Eustachian Tube (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved 124-94-7 31307
2 Triamcinolone hexacetonide
3 Triamcinolone diacetate
4 triamcinolone acetonide

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Trial of Clay Weight on the Ear Drum for Patulous Eustachian Tube Unknown status NCT00933478
2 Risk Factors and Potential Causes of Eustachian Tube Dysfunction in Adults Completed NCT01251432

Search NIH Clinical Center for Patulous Eustachian Tube

Genetic Tests for Patulous Eustachian Tube

Anatomical Context for Patulous Eustachian Tube

MalaCards organs/tissues related to Patulous Eustachian Tube:

42
Prostate, Brain, Breast, Bone, Lymph Node, Thyroid, T Cells

Publications for Patulous Eustachian Tube

Articles related to Patulous Eustachian Tube:

(show top 50) (show all 2912)
# Title Authors Year
1
Optimal respiratory-gated [18F]FDG PET/CT significantly impacts the quantification of metabolic parameters and their correlation with overall survival in patients with pancreatic ductal adenocarcinoma. ( 30868318 )
2019
2
Correction: Solitary ground-glass opacity nodules of stage IA pulmonary adenocarcinoma: combination of 18F-FDG PET/CT and high-resolution computed tomography features to predict invasive adenocarcinoma. ( 30838094 )
2019
3
Perioperative EOX treatment in operable locally advanced gastroesophageal adenocarcinoma: Prediction of tumor response by FDG -PET and histopathology. ( 30851910 )
2019
4
18F-FDG PET/CT of Lung Adenocarcinoma With Ovarian Metastases. ( 30789397 )
2019
5
Recurrent pancreatic adenocarcinoma depicted by 18F-fluciclovine PET/CT imaging. ( 30718122 )
2019
6
Concurrent Pancreatic Metastasis From Lung Adenocarcinoma and Primary Cholangiocarcinoma on FDG PET/CT Imaging. ( 30762824 )
2019
7
Impact of different image reconstructions on PET quantification in non-small cell lung cancer: a comparison of adenocarcinoma and squamous cell carcinoma. ( 30673302 )
2019
8
Usefulness of FDG PET/CT derived parameters in prediction of histopathological finding during the surgery in patients with pancreatic adenocarcinoma. ( 30629646 )
2019
9
Prospective comparison of (4S)-4-(3-18F-fluoropropyl)-L-glutamate versus 18F-fluorodeoxyglucose PET/CT for detecting metastases from pancreatic ductal adenocarcinoma: a proof-of-concept study. ( 30635754 )
2019
10
Prognostic impact of combining whole-body PET/CT and brain PET/MR in patients with lung adenocarcinoma and brain metastases. ( 30415280 )
2019
11
Solitary Mucinous Prostate Adenocarcinoma Lung Metastasis Detected by 68Ga-PSMA-11 PET/CT. ( 30293922 )
2019
12
Pretreatment quantitative 18F-FDG PET/CT parameters as a predictor of survival in adenoid cystic carcinoma of the salivary glands. ( 30308429 )
2019
13
18 F-FDG PET/MRI vs MRI in patients with recurrent adenoid cystic carcinoma. ( 30548894 )
2019
14
Ectopic thyroid-stimulating hormone-secreting pituitary adenoma of the nasopharynx diagnosed by 68Ga-DOTA-TATE PET/CT. ( 30797906 )
2019
15
FDG PET/CT findings in adult-onset Still's disease. ( 30828734 )
2019
16
A pilot study demonstrating cardiac uptake with 18F-florbetapir PET in AL amyloidosis patients with cardiac involvement. ( 30661419 )
2019
17
A Rare Case of Neutrophil-Rich, ALK-Negative Anaplastic Large Cell Lymphoma in the Lung Mimicking a Pulmonary Abscess on 18F-FDG PET/CT. ( 30562196 )
2019
18
Doughnut sign of hepatic alveolar echinococcosis on FDG PET/CT: Clinical case report. ( 30813170 )
2019
19
FDG-PET/MRI Imaging for the Management of Alveolar Echinococcosis: Initial Clinical Experience at a Reference Centre in Austria. ( 30851233 )
2019
20
A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain. ( 30398430 )
2019
21
In Vivo Characterization and Quantification of Neurofibrillary Tau PET Radioligand 18F-MK-6240 in Humans from Alzheimer Disease Dementia to Young Controls. ( 29777006 )
2019
22
Detection of cardiac amyloidosis with 18F-Florbetaben-PET/CT in comparison to echocardiography, cardiac MRI and DPD-scintigraphy. ( 30798427 )
2019
23
Examining the sensitivity of 18F-NaF PET for the imaging of cardiac amyloidosis. ( 30834499 )
2019
24
68Ga-PSMA Uptake in Anal Fistula on PET/CT Scan. ( 30540600 )
2019
25
Anaplastic Oligodendroglioma Found as an Incidental Photopenic Lesion on 18F-FP-CIT PET/CT Image. ( 30672761 )
2019
26
PET/CT and MR Features of Infiltrating Spinal Angiolipoma. ( 30516665 )
2019
27
Primary and Secondary Breast Angiosarcoma: FDG PET/CT Series. ( 30371579 )
2019
28
Primary Common Iliac Artery Angiosarcoma With Multiple Bone Metastases Revealed by Dual-Time Point FDG PET/CT Imaging. ( 30624266 )
2019
29
The effect of a pet therapy and comparison intervention on anxiety in hospitalized children. ( 30852256 )
2019
30
Depression and anxiety in pet owners after a diagnosis of cancer in their pets: a cross-sectional study in Japan. ( 30782907 )
2019
31
Role of Cerebrospinal Fluid Biomarkers and (18)F-florbetapir PET Imaging in the Diagnosis of Primary Progressive Aphasia: A Retrospective Analysis. ( 30640253 )
2019
32
Development and validation of an 18 F-FDG PET/CT-based tool for the evaluation of joint counts and disease activity in patients with rheumatoid arthritis. ( 30771237 )
2019
33
Bifrontal Hypermetabolism on Brain FDG-PET in a Case of C9orf72-Related Behavioral Variant of Frontotemporal Dementia. ( 30404533 )
2019
34
Measurement of 18F-FDG PET tumor heterogeneity improves early assessment of response to bevacizumab compared with the standard size and uptake metrics in a colorectal cancer model. ( 30893213 )
2019
35
Combining 18F-FDG PET/CT-based Metabolically Active Tumor Volume and Circulating Cell-free DNA Significantly Improves Outcome Prediction in Chemorefractory Metastatic Colorectal Cancer. ( 30850494 )
2019
36
Diagnostic performance of F-18 FDG PET/CT for prediction of KRAS mutation in colorectal cancer patients: a systematic review and meta-analysis. ( 30603881 )
2019
37
The significant value of predicting prognosis in patients with colorectal cancer using 18F-FDG PET metabolic parameters of primary tumors and hematological parameters. ( 30218280 )
2019
38
18F-FDG PET/CT AS AN ASSESSMENT TOOL OF HEPATOCELLULAR CARCINOMA SECONDARY TO NON-ALCOHOLIC FATTY LIVER DISEASE DEVELOPMENT IN EXPERIMENTAL MODEL. ( 30892403 )
2019
39
Transcriptomics associates molecular features with 18F-fluorocholine PET/CT imaging phenotype and its potential relationship to survival in hepatocellular carcinoma. ( 30760520 )
2019
40
Hepatocellular Carcinoma Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE PET/CT. ( 30688738 )
2019
41
68Ga-DOTANOC PET/CT Detects Multifocal Hepatocellular Carcinoma. ( 30672751 )
2019
42
Telbivudine-Induced Myopathy Incidentally Detected by FDG PET/CT Imaging in a Patient With History of Hepatocellular Carcinoma. ( 30608913 )
2019
43
FDG PET/CT Imaging of Hepatocellular Carcinoma With Bile Duct Tumor Thrombus. ( 30562190 )
2019
44
18F-fluorodeoxyglucose positron emission tomography (18FDG-PET) for patients with biliary tract cancer: systematic review and meta-analysis. ( 30797051 )
2019
45
Integrated analysis of 18F-FDG PET/CT improves preoperative lymph node staging for patients with invasive bladder cancer. ( 30666449 )
2019
46
Vascular Burden Score Impacts Cognition Independent of Amyloid PET and MRI Measures of Alzheimer's Disease and Vascular Brain Injury. ( 30775991 )
2019
47
PET/CT radiomics in breast cancer: promising tool for prediction of pathological response to neoadjuvant chemotherapy. ( 30915523 )
2019
48
Investigation of appropriate semi-quantitative index for assessment of esophageal and breast cancer treatment response in Japanese patients using 18F-FDG PET/CT findings. ( 30843006 )
2019
49
Prognostic value of 18F-FDG PET/CT prior to breast cancer treatment. Comparison with magnetic resonance spectroscopy and diffusion weighted imaging. ( 30843007 )
2019
50
Diagnostic accuracy and safety of 16α-[18F]fluoro-17β-oestradiol PET-CT for the assessment of oestrogen receptor status in recurrent or metastatic lesions in patients with breast cancer: a prospective cohort study. ( 30846327 )
2019

Variations for Patulous Eustachian Tube

Expression for Patulous Eustachian Tube

Search GEO for disease gene expression data for Patulous Eustachian Tube.

Pathways for Patulous Eustachian Tube

GO Terms for Patulous Eustachian Tube

Sources for Patulous Eustachian Tube

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63 PubMed
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70 SNOMED-CT via HPO
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72 TGDB
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74 UMLS
75 UMLS via Orphanet
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