MCID: PDT002
MIFTS: 22

Pediatric Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Pediatric Meningioma

MalaCards integrated aliases for Pediatric Meningioma:

Name: Pediatric Meningioma 12 15
Childhood Meningioma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4593
NCIt 49 C8264
UMLS 71 C0280656

Summaries for Pediatric Meningioma

MalaCards based summary : Pediatric Meningioma, also known as childhood meningioma, is related to spinal meningioma and secretory meningioma. An important gene associated with Pediatric Meningioma is LUC7L2 (LUC7 Like 2, Pre-MRNA Splicing Factor). The drugs Dexamethasone acetate and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and liver.

Related Diseases for Pediatric Meningioma

Diseases related to Pediatric Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
# Related Disease Score Top Affiliating Genes
1 spinal meningioma 30.4 TRAF7 NF2
2 secretory meningioma 30.3 TRAF7 NF2
3 neurofibromatosis, type iv, of riccardi 29.7 NF2 KIAA1549
4 fibrous meningioma 29.6 TRAF7 NF2
5 meningioma, familial 29.5 TRAF7 NF2 KIAA1549
6 childhood brain meningioma 11.3
7 meningioma, radiation-induced 10.2
8 lymphoplasmacyte-rich meningioma 10.2
9 intraventricular meningioma 10.1 TRAF7 NF2
10 brain meningioma 10.1 TRAF7 NF2
11 olfactory groove meningioma 10.1 TRAF7 NF2
12 psammomatous meningioma 10.1 TRAF7 NF2
13 anterior cranial fossa meningioma 10.1 TRAF7 NF2
14 intraneural perineurioma 10.0 TRAF7 NF2
15 spinal canal and spinal cord meningioma 10.0 TRAF7 NF2
16 transitional meningioma 10.0 TRAF7 NF2
17 meningothelial meningioma 10.0 TRAF7 NF2
18 rhabdoid meningioma 10.0 TRAF7 NF2
19 skull base cancer 10.0 TRAF7 NF2
20 skull base meningioma 10.0 TRAF7 NF2
21 clear cell meningioma 10.0 TRAF7 NF2
22 frontal convexity meningioma 10.0 TRAF7 NF2
23 childhood pilocytic astrocytoma 10.0 LUC7L2 KIAA1549
24 optic nerve neoplasm 10.0 NF2 KIAA1549
25 adult astrocytic tumour 10.0 LUC7L2 KIAA1549
26 juvenile astrocytoma 9.9 LUC7L2 KIAA1549
27 optic nerve glioma 9.9 NF2 KIAA1549
28 malignant ependymoma 9.9 NF2 KIAA1549
29 cerebral ventricle cancer 9.9 NF2 KIAA1549
30 benign meningioma 9.9 TRAF7 NF2
31 dysembryoplastic neuroepithelial tumor 9.9 LUC7L2 KIAA1549
32 intracranial hypertension 9.9
33 monosomy 22 9.9
34 cerebrum cancer 9.9 NF2 KIAA1549
35 fibrillary astrocytoma 9.8 LUC7L2 KIAA1549
36 supratentorial cancer 9.8 NF2 KIAA1549
37 juvenile pilocytic astrocytoma 9.8 LUC7L2 KIAA1549
38 pilomyxoid astrocytoma 9.8 LUC7L2 KIAA1549
39 neurofibromatosis, type ii 9.7
40 parasagittal meningioma 9.7
41 spinal cord ependymoma 9.7 NF2 LUC7L2 KIAA1549
42 spinal cord glioma 9.7 NF2 LUC7L2 KIAA1549
43 spinal cancer 9.7 NF2 LUC7L2 KIAA1549
44 myxopapillary ependymoma 9.7 NF2 LUC7L2 KIAA1549
45 central nervous system benign neoplasm 9.7 NF2 LUC7L2 KIAA1549
46 ganglioglioma 9.6 LUC7L2 KIAA1549
47 central nervous system cancer 9.4 NF2 KIAA1549

Graphical network of the top 20 diseases related to Pediatric Meningioma:



Diseases related to Pediatric Meningioma

Symptoms & Phenotypes for Pediatric Meningioma

Drugs & Therapeutics for Pediatric Meningioma

Drugs for Pediatric Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 30)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
2
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
3
Cisplatin Approved Phase 3 15663-27-1 84093 441203 2767
4
Ondansetron Approved Phase 3 99614-02-5 4595
5
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
6 Gastrointestinal Agents Phase 3
7 Autonomic Agents Phase 3
8 BB 1101 Phase 3
9 Emetics Phase 3
10 Antiemetics Phase 3
11
Doxorubicin Approved, Investigational Phase 1 23214-92-8 31703
12 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole Phase 1
13 Anti-Inflammatory Agents Phase 1
14 Analgesics, Non-Narcotic Phase 1
15 Anti-Inflammatory Agents, Non-Steroidal Phase 1
16 Antirheumatic Agents Phase 1
17 Analgesics Phase 1
18 Anti-Bacterial Agents Phase 1
19 Liver Extracts Phase 1
20 Antibiotics, Antitubercular Phase 1
21 Topoisomerase Inhibitors Phase 1
22
Liposomal doxorubicin Phase 1 31703
23
Hyaluronic acid Approved, Vet_approved 9004-61-9 53477741
24
Povidone Approved 9003-39-8
25 Plasma Substitutes
26 Viscosupplements
27 Adjuvants, Immunologic
28 Blood Substitutes
29 Protective Agents
30 Immunologic Factors

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Controlled Trial of Acupressure to Control Chemotherapy-Induced Nausea (CIN) in Children Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
2 Phase I and Pharmacokinetic Trial of PTC299 in Pediatric Patients With Refractory or Recurrent CNS Tumors Completed NCT01158300 Phase 1 VEGF inhibitor PTC299
3 Phase I Study of Doxorubicin HCl Liposome in Pediatric Patients With Refractory Solid Tumors Completed NCT00019630 Phase 1 doxorubicin HCl liposome
4 Efficacy of Gelclair™ in Reducing the Pain of Oral Mucositis in Children and Young People With Cancer (SC 2005 07) Unknown status NCT00349024 polyvinylpyrrolidone-sodium hyaluronate gel
5 A Pharmacokinetic Participation Questionnaire Study Completed NCT00890435
6 Barriers to Patient Enrollment Onto Frontline Therapeutic Clinical Trials and Development of Intervention Strategies to Increase the Proportion of Enrollment Completed NCT00002485
7 Pilot Study of Early Enteral Tube Feedings in Children Receiving Chemotherapy for Newly Diagnosed AML/MDS and High Risk Solid Tumors Withdrawn NCT00624962

Search NIH Clinical Center for Pediatric Meningioma

Genetic Tests for Pediatric Meningioma

Anatomical Context for Pediatric Meningioma

MalaCards organs/tissues related to Pediatric Meningioma:

40
Spinal Cord, Brain, Liver, Lymph Node

Publications for Pediatric Meningioma

Articles related to Pediatric Meningioma:

(show all 19)
# Title Authors PMID Year
1
Pediatric meningiomas: a report of 5 cases and review of literature. 61
31001646 2019
2
Long-term outcomes of pediatric meningioma surgery: single center experience with 23 patients. 61
31736038 2019
3
Management of pediatric CNS meningiomas: CCHE-57357 experience in 39 cases. 61
31127346 2019
4
Contralateral facial nerve paresis subsequent to posterior fossa meningioma surgery in a child: case report. 61
30643949 2019
5
Nasopharyngeal tumor developing in a 36-year-old man following radiation for a childhood meningioma. 61
28414885 2017
6
Prediction of pediatric meningioma recurrence by preoperative MRI assessment. 61
27037557 2016
7
Anterolateral meningioma of the foramen magnum and high cervical spine presenting intradural and extradural growth in a child: case report and literature review. 61
26077596 2015
8
The importance of microsurgery in childhood meningioma: a case report. 61
25034239 2015
9
Intracranial meningiomas managed at Memfys hospital for neurosurgery in Enugu, Nigeria. 61
23188985 2012
10
Meningioma as second malignant neoplasm after oncological treatment during childhood. 61
22410835 2012
11
Pediatric meningioma: current approaches and future direction. 61
21203895 2011
12
Childhood and juvenile meningiomas. 61
19641924 2009
13
Aggressive pediatric meningioma with soft tissue and lymph node metastases: a case report. 61
19086745 2009
14
Meningiomas in children. 61
18097185 2008
15
Childhood meningioma: unusual location, atypical radiological findings, and favorable treatment outcome. 61
11734983 2001
16
Paediatric presentation of type 2 neurofibromatosis. 61
10569966 1999
17
[The clinical analysis of pediatric meningioma: 5 cases]. 61
9027889 1997
18
Meningioma in children: a report of nine cases and a review of the literature. 61
8607080 1996
19
Childhood meningioma associated with meningio-angiomatosis. Case report. 61
8421212 1993

Variations for Pediatric Meningioma

Expression for Pediatric Meningioma

Search GEO for disease gene expression data for Pediatric Meningioma.

Pathways for Pediatric Meningioma

GO Terms for Pediatric Meningioma

Sources for Pediatric Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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