MCID: PDT002
MIFTS: 24

Pediatric Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Pediatric Meningioma

MalaCards integrated aliases for Pediatric Meningioma:

Name: Pediatric Meningioma 12 15
Childhood Meningioma 72

Classifications:



External Ids:

Disease Ontology 12 DOID:4593
NCIt 50 C8264
UMLS 72 C0280656

Summaries for Pediatric Meningioma

MalaCards based summary : Pediatric Meningioma, also known as childhood meningioma, is related to secretory meningioma and meningioma, radiation-induced. An important gene associated with Pediatric Meningioma is NF2 (Neurofibromin 2). The drugs Dexamethasone and Granisetron have been mentioned in the context of this disorder. Affiliated tissues include liver and lymph node, and related phenotypes are neoplasm and normal

Related Diseases for Pediatric Meningioma

Graphical network of the top 20 diseases related to Pediatric Meningioma:



Diseases related to Pediatric Meningioma

Symptoms & Phenotypes for Pediatric Meningioma

MGI Mouse Phenotypes related to Pediatric Meningioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.26 F3 KLF4 NF2 PGR
2 normal MP:0002873 9.02 F3 KLF4 PGR SAMHD1 STMN1

Drugs & Therapeutics for Pediatric Meningioma

Drugs for Pediatric Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
2
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
3
Cisplatin Approved Phase 3 15663-27-1 84093 441203 2767
4
Ondansetron Approved Phase 3 99614-02-5 4595
5
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
6 Peripheral Nervous System Agents Phase 3
7 Gastrointestinal Agents Phase 3
8 Antiemetics Phase 3
9 Autonomic Agents Phase 3
10 BB 1101 Phase 3
11 Emetics Phase 3
12
Doxorubicin Approved, Investigational Phase 1 23214-92-8 31703
13 Analgesics Phase 1
14 Analgesics, Non-Narcotic Phase 1
15 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole Phase 1
16 Anti-Inflammatory Agents, Non-Steroidal Phase 1
17 Anti-Inflammatory Agents Phase 1
18 Antirheumatic Agents Phase 1
19
Liposomal doxorubicin Phase 1 31703
20 Anti-Bacterial Agents Phase 1
21 Antibiotics, Antitubercular Phase 1
22 Topoisomerase Inhibitors Phase 1
23 Liver Extracts Phase 1
24
Povidone Approved 9003-39-8
25
Hyaluronic acid Approved, Vet_approved 9004-61-9 53477741
26 Adjuvants, Immunologic
27 Protective Agents
28 Viscosupplements
29 Plasma Substitutes
30 Immunologic Factors
31 Blood Substitutes

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Controlled Trial of Acupressure to Control Chemotherapy-Induced Nausea (CIN) in Children Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
2 Phase I and Pharmacokinetic Trial of PTC299 in Pediatric Patients With Refractory or Recurrent CNS Tumors Completed NCT01158300 Phase 1 VEGF inhibitor PTC299
3 Phase I Study of Doxorubicin HCl Liposome in Pediatric Patients With Refractory Solid Tumors Completed NCT00019630 Phase 1 doxorubicin HCl liposome
4 Efficacy of Gelclair™ in Reducing the Pain of Oral Mucositis in Children and Young People With Cancer (SC 2005 07) Unknown status NCT00349024 polyvinylpyrrolidone-sodium hyaluronate gel
5 A Pharmacokinetic Participation Questionnaire Study Completed NCT00890435
6 Barriers to Patient Enrollment Onto Frontline Therapeutic Clinical Trials and Development of Intervention Strategies to Increase the Proportion of Enrollment Completed NCT00002485
7 Pilot Study of Early Enteral Tube Feedings in Children Receiving Chemotherapy for Newly Diagnosed AML/MDS and High Risk Solid Tumors Withdrawn NCT00624962

Search NIH Clinical Center for Pediatric Meningioma

Genetic Tests for Pediatric Meningioma

Anatomical Context for Pediatric Meningioma

MalaCards organs/tissues related to Pediatric Meningioma:

41
Liver, Lymph Node

Publications for Pediatric Meningioma

Articles related to Pediatric Meningioma:

(show all 18)
# Title Authors PMID Year
1
Management of pediatric CNS meningiomas: CCHE-57357 experience in 39 cases. 38
31127346 2019
2
Contralateral facial nerve paresis subsequent to posterior fossa meningioma surgery in a child: case report. 38
30643949 2019
3
Pediatric meningiomas: a report of 5 cases and review of literature. 38
31001646 2019
4
Nasopharyngeal tumor developing in a 36-year-old man following radiation for a childhood meningioma. 38
28414885 2017
5
Prediction of pediatric meningioma recurrence by preoperative MRI assessment. 38
27037557 2016
6
Anterolateral meningioma of the foramen magnum and high cervical spine presenting intradural and extradural growth in a child: case report and literature review. 38
26077596 2015
7
The importance of microsurgery in childhood meningioma: a case report. 38
25034239 2015
8
Intracranial meningiomas managed at Memfys hospital for neurosurgery in Enugu, Nigeria. 38
23188985 2012
9
Meningioma as second malignant neoplasm after oncological treatment during childhood. 38
22410835 2012
10
Pediatric meningioma: current approaches and future direction. 38
21203895 2011
11
Childhood and juvenile meningiomas. 38
19641924 2009
12
Aggressive pediatric meningioma with soft tissue and lymph node metastases: a case report. 38
19086745 2009
13
Meningiomas in children. 38
18097185 2008
14
Childhood meningioma: unusual location, atypical radiological findings, and favorable treatment outcome. 38
11734983 2001
15
Paediatric presentation of type 2 neurofibromatosis. 38
10569966 1999
16
[The clinical analysis of pediatric meningioma: 5 cases]. 38
9027889 1997
17
Meningioma in children: a report of nine cases and a review of the literature. 38
8607080 1996
18
Childhood meningioma associated with meningio-angiomatosis. Case report. 38
8421212 1993

Variations for Pediatric Meningioma

Expression for Pediatric Meningioma

Search GEO for disease gene expression data for Pediatric Meningioma.

Pathways for Pediatric Meningioma

GO Terms for Pediatric Meningioma

Molecular functions related to Pediatric Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 zinc ion binding GO:0008270 8.92 TRAF7 SAMHD1 PGR KLF4

Sources for Pediatric Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....