MCID: PDT003
MIFTS: 23

Pediatric Ovarian Dysgerminoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Pediatric Ovarian Dysgerminoma

MalaCards integrated aliases for Pediatric Ovarian Dysgerminoma:

Name: Pediatric Ovarian Dysgerminoma 12 15
Childhood Ovarian Dysgerminoma 72

Classifications:



External Ids:

Disease Ontology 12 DOID:7340
NCIt 50 C6550
UMLS 72 C1332988

Summaries for Pediatric Ovarian Dysgerminoma

Disease Ontology : 12 A dysgerminoma of ovary that occurs in children.

MalaCards based summary : Pediatric Ovarian Dysgerminoma, also known as childhood ovarian dysgerminoma, is related to dysgerminoma and dysgerminoma of ovary, and has symptoms including abdominal pain An important gene associated with Pediatric Ovarian Dysgerminoma is ENO2 (Enolase 2), and among its related pathways/superpathways are Presynaptic function of Kainate receptors and G alpha (s) signalling events. Affiliated tissues include ovary, and related phenotype is craniofacial.

Related Diseases for Pediatric Ovarian Dysgerminoma

Graphical network of the top 20 diseases related to Pediatric Ovarian Dysgerminoma:



Diseases related to Pediatric Ovarian Dysgerminoma

Symptoms & Phenotypes for Pediatric Ovarian Dysgerminoma

UMLS symptoms related to Pediatric Ovarian Dysgerminoma:


abdominal pain

MGI Mouse Phenotypes related to Pediatric Ovarian Dysgerminoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 8.8 ENO2 PTH PTHLH

Drugs & Therapeutics for Pediatric Ovarian Dysgerminoma

Search Clinical Trials , NIH Clinical Center for Pediatric Ovarian Dysgerminoma

Genetic Tests for Pediatric Ovarian Dysgerminoma

Anatomical Context for Pediatric Ovarian Dysgerminoma

MalaCards organs/tissues related to Pediatric Ovarian Dysgerminoma:

41
Ovary

Publications for Pediatric Ovarian Dysgerminoma

Articles related to Pediatric Ovarian Dysgerminoma:

# Title Authors PMID Year
1
Two Cases of Hypercalcemia in Pediatric Ovarian Dysgerminoma. 38
30551952 2019
2
Pediatric ovarian dysgerminoma with highly elevated serum neuron-specific enolase. 38
30345703 2018
3
Pediatric ovarian dysgerminoma presenting with hypercalcemia and chronic constipation: a case report. 38
23799522 2013
4
A case of pediatric ovarian dysgerminoma associated with high serum levels and positive immunohistochemical staining of neuron-specific enolase. 38
15359410 2004

Variations for Pediatric Ovarian Dysgerminoma

Expression for Pediatric Ovarian Dysgerminoma

Search GEO for disease gene expression data for Pediatric Ovarian Dysgerminoma.

Pathways for Pediatric Ovarian Dysgerminoma

GO Terms for Pediatric Ovarian Dysgerminoma

Biological processes related to Pediatric Ovarian Dysgerminoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.4 PTHLH PTH
2 regulation of gene expression GO:0010468 9.37 PTHLH PTH
3 skeletal system development GO:0001501 9.32 PTHLH PTH
4 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 9.26 PTHLH PTH
5 negative regulation of chondrocyte differentiation GO:0032331 8.96 PTHLH PTH
6 bone mineralization GO:0030282 8.85 PTHLH
7 cAMP metabolic process GO:0046058 8.62 PTHLH PTH

Molecular functions related to Pediatric Ovarian Dysgerminoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 magnesium ion binding GO:0000287 9.16 ENO2 ALPP
2 hormone activity GO:0005179 8.96 PTHLH PTH
3 peptide hormone receptor binding GO:0051428 8.62 PTHLH PTH

Sources for Pediatric Ovarian Dysgerminoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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