MCID: PDT003
MIFTS: 26

Pediatric Ovarian Dysgerminoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Pediatric Ovarian Dysgerminoma

MalaCards integrated aliases for Pediatric Ovarian Dysgerminoma:

Name: Pediatric Ovarian Dysgerminoma 12 15
Childhood Ovarian Dysgerminoma 74

Classifications:



External Ids:

Disease Ontology 12 DOID:7340
NCIt 51 C6550
UMLS 74 C1332988

Summaries for Pediatric Ovarian Dysgerminoma

Disease Ontology : 12 A dysgerminoma of ovary that occurs in children.

MalaCards based summary : Pediatric Ovarian Dysgerminoma, also known as childhood ovarian dysgerminoma, is related to dysgerminoma of ovary and dysgerminoma, and has symptoms including abdominal pain An important gene associated with Pediatric Ovarian Dysgerminoma is ENO2 (Enolase 2), and among its related pathways/superpathways are Presynaptic function of Kainate receptors and G alpha (s) signalling events. Affiliated tissues include ovary and bone, and related phenotype is craniofacial.

Related Diseases for Pediatric Ovarian Dysgerminoma

Graphical network of the top 20 diseases related to Pediatric Ovarian Dysgerminoma:



Diseases related to Pediatric Ovarian Dysgerminoma

Symptoms & Phenotypes for Pediatric Ovarian Dysgerminoma

UMLS symptoms related to Pediatric Ovarian Dysgerminoma:


abdominal pain

MGI Mouse Phenotypes related to Pediatric Ovarian Dysgerminoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 8.8 ENO2 PTH PTHLH

Drugs & Therapeutics for Pediatric Ovarian Dysgerminoma

Search Clinical Trials , NIH Clinical Center for Pediatric Ovarian Dysgerminoma

Genetic Tests for Pediatric Ovarian Dysgerminoma

Anatomical Context for Pediatric Ovarian Dysgerminoma

MalaCards organs/tissues related to Pediatric Ovarian Dysgerminoma:

42
Ovary, Bone

Publications for Pediatric Ovarian Dysgerminoma

Articles related to Pediatric Ovarian Dysgerminoma:

# Title Authors Year
1
Two Cases of Hypercalcemia in Pediatric Ovarian Dysgerminoma. ( 30551952 )
2019
2
Pediatric ovarian dysgerminoma with highly elevated serum neuron-specific enolase. ( 30345703 )
2018
3
Pediatric ovarian dysgerminoma presenting with hypercalcemia and chronic constipation: a case report. ( 23799522 )
2013
4
A case of pediatric ovarian dysgerminoma associated with high serum levels and positive immunohistochemical staining of neuron-specific enolase. ( 15359410 )
2004

Variations for Pediatric Ovarian Dysgerminoma

Expression for Pediatric Ovarian Dysgerminoma

Search GEO for disease gene expression data for Pediatric Ovarian Dysgerminoma.

Pathways for Pediatric Ovarian Dysgerminoma

GO Terms for Pediatric Ovarian Dysgerminoma

Biological processes related to Pediatric Ovarian Dysgerminoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.4 PTH PTHLH
2 regulation of gene expression GO:0010468 9.37 PTH PTHLH
3 skeletal system development GO:0001501 9.32 PTH PTHLH
4 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 9.26 PTH PTHLH
5 negative regulation of chondrocyte differentiation GO:0032331 8.96 PTH PTHLH
6 bone mineralization GO:0030282 8.85 PTHLH
7 cAMP metabolic process GO:0046058 8.62 PTH PTHLH

Molecular functions related to Pediatric Ovarian Dysgerminoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 magnesium ion binding GO:0000287 9.16 ALPP ENO2
2 hormone activity GO:0005179 8.96 PTH PTHLH
3 peptide hormone receptor binding GO:0051428 8.62 PTH PTHLH

Sources for Pediatric Ovarian Dysgerminoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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