MCID: PDC002
MIFTS: 24

Pediculus Humanus Capitis Infestation

Categories: Infectious diseases

Aliases & Classifications for Pediculus Humanus Capitis Infestation

MalaCards integrated aliases for Pediculus Humanus Capitis Infestation:

Name: Pediculus Humanus Capitis Infestation 12 15
Pediculus Capitis Infestation 12 73
Head Louse Infestation 12
Pediculosis Capitis 12
Pediculus Capitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5501
ICD10 33 B85.0
ICD9CM 35 132.0
UMLS 73 C0030757

Summaries for Pediculus Humanus Capitis Infestation

Disease Ontology : 12 A lice infestation that involves colonization of the hair and skin by the parasitic insect Pediculus humanus capitis, which feeds on blood several times daily and resides close to the scalp to maintain its body temperature. The symptoms include tickling feeling of something moving in the hair, itching, caused by an allergic reaction to louse saliva, and irritability.

MalaCards based summary : Pediculus Humanus Capitis Infestation, also known as pediculus capitis infestation, is related to lice infestation and white piedra. An important gene associated with Pediculus Humanus Capitis Infestation is SPINK5 (Serine Peptidase Inhibitor, Kazal Type 5), and among its related pathways/superpathways is Cell adhesion_Plasmin signaling. The drugs Ivermectin and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include skin and colon.

Related Diseases for Pediculus Humanus Capitis Infestation

Diseases related to Pediculus Humanus Capitis Infestation via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 lice infestation 30.5 HOTAIR KDR MT-CO1
2 white piedra 10.2
3 scabies 10.2
4 elephantiasis 10.1
5 renal cell carcinoma, nonpapillary 9.6 HOTAIR KDR
6 pre-eclampsia 9.5 HOTAIR KDR
7 parasitic ectoparasitic infectious disease 9.4 KDR MT-CO1
8 glioma 9.2 HOTAIR KDR
9 parasitic protozoa infectious disease 8.9 KDR MT-CO1 SPINK5

Comorbidity relations with Pediculus Humanus Capitis Infestation via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Pediculus Humanus Capitis Infestation:



Diseases related to Pediculus Humanus Capitis Infestation

Symptoms & Phenotypes for Pediculus Humanus Capitis Infestation

Drugs & Therapeutics for Pediculus Humanus Capitis Infestation

Drugs for Pediculus Humanus Capitis Infestation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ivermectin Approved, Investigational, Vet_approved Phase 3,Phase 2 70288-86-7 6474909
2 Anti-Infective Agents Phase 3,Phase 2
3 Antiparasitic Agents Phase 3,Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Safety and Efficacy Study Comparing 0.5% Ivermectin Cream to a Vehicle Control in Subjects With Head Lice Infestation Completed NCT01066585 Phase 3 Ivermectin Cream;vehicle control
2 A Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects Completed NCT01068158 Phase 3 0.5% Ivermectin Cream;Placebo control
3 Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects Completed NCT00994422 Phase 2 Ivermectin cream;vehicle control

Search NIH Clinical Center for Pediculus Humanus Capitis Infestation

Genetic Tests for Pediculus Humanus Capitis Infestation

Anatomical Context for Pediculus Humanus Capitis Infestation

MalaCards organs/tissues related to Pediculus Humanus Capitis Infestation:

41
Skin, Colon

Publications for Pediculus Humanus Capitis Infestation

Articles related to Pediculus Humanus Capitis Infestation:

# Title Authors Year
1
Treatment of head lice (Pediculus humanus capitis) infestation: Is regular combing alone with a special detection comb effective at all levels? ( 25604670 )
2015
2
Prehistorical Pediculus humanus capitis infestation: quantitative data and low vacuum scanning microscopy. ( 24626412 )
2014
3
Prevalence of Pediculus humanus capitis infestation among kindergarten children in BahA-a Blanca city, Argentina. ( 22752696 )
2012
4
Impact of ivermectin drug combinations on Pediculus humanus capitis infestation in primary schoolchildren of south Indian rural villages. ( 20064176 )
2009
5
Economic considerations associated with Pediculus humanus capitis infestation. ( 15248004 )
2004
6
Pediculus humanus capitis infestation in a Shiraz rural area, Iran. ( 17283477 )
1999
7
Chemotherapy of head louse (Pediculus humanus capitis) infestation gamma benzene hexachloride (gamma-BHC) among school children in Szu-Hu District, Yunlin County, Central West Taiwan. ( 1715809 )
1991
8
Comparative study of DDT, carbaryl (Sevin) and Actellic (pirimiphos-methyl) in the treatment of Pediculus humanus capitis infestation. ( 6405446 )
1983
9
Epidemiology of Pediculus humanus capitis infestation in Malaysian school children. ( 7258487 )
1981

Variations for Pediculus Humanus Capitis Infestation

Expression for Pediculus Humanus Capitis Infestation

Search GEO for disease gene expression data for Pediculus Humanus Capitis Infestation.

Pathways for Pediculus Humanus Capitis Infestation

Pathways related to Pediculus Humanus Capitis Infestation according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.31 KDR SPINK5

GO Terms for Pediculus Humanus Capitis Infestation

Biological processes related to Pediculus Humanus Capitis Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 8.62 KDR SPINK5

Sources for Pediculus Humanus Capitis Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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