MCID: PDC002
MIFTS: 25

Pediculus Humanus Capitis Infestation

Categories: Infectious diseases

Aliases & Classifications for Pediculus Humanus Capitis Infestation

MalaCards integrated aliases for Pediculus Humanus Capitis Infestation:

Name: Pediculus Humanus Capitis Infestation 12 15
Pediculus Capitis Infestation 12 71
Head Louse Infestation 12
Pediculosis Capitis 12
Pediculus Capitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5501
ICD9CM 34 132.0
SNOMED-CT 67 81000006
ICD10 32 B85.0
UMLS 71 C0030757

Summaries for Pediculus Humanus Capitis Infestation

Disease Ontology : 12 A lice infestation that involves colonization of the hair and skin by the parasitic insect Pediculus humanus capitis, which feeds on blood several times daily and resides close to the scalp to maintain its body temperature. The symptoms include tickling feeling of something moving in the hair, itching, caused by an allergic reaction to louse saliva, and irritability.

MalaCards based summary : Pediculus Humanus Capitis Infestation, also known as pediculus capitis infestation, is related to lice infestation and scabies. An important gene associated with Pediculus Humanus Capitis Infestation is KDR (Kinase Insert Domain Receptor). The drugs Malathion and Ivermectin have been mentioned in the context of this disorder.

Related Diseases for Pediculus Humanus Capitis Infestation

Diseases related to Pediculus Humanus Capitis Infestation via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 30)
# Related Disease Score Top Affiliating Genes
1 lice infestation 10.8
2 scabies 10.4
3 skin disease 10.3
4 exanthem 10.3
5 superficial mycosis 10.2
6 white piedra 10.2
7 iron metabolism disease 10.2
8 dermatitis 10.2
9 alopecia 10.2
10 plague 10.1
11 anoxia 10.1
12 melkersson-rosenthal syndrome 10.1
13 deficiency anemia 10.1
14 iron deficiency anemia 10.1
15 ocular hyperemia 10.1
16 elephantiasis 10.1
17 conjunctivitis 10.1
18 impetigo 10.1
19 hypereosinophilic syndrome 10.1
20 bacillary angiomatosis 9.9 MT-CYB COX18
21 trench fever 9.9 MT-CYB COX18
22 bartonellosis 9.8 MT-CYB COX18
23 coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or mental retardation 9.8 MT-CYB COX18
24 articulation disorder 9.8 MT-CYB LINC01554
25 epidemic typhus 9.8 MT-CYB COX18
26 stuttering 9.8 MT-CYB LINC01554
27 parasitic protozoa infectious disease 9.7 MT-CYB KDR
28 speech disorder 9.7 MT-CYB LINC01554
29 pediculus humanus corporis infestation 9.7 TMEM11 MT-CYB
30 neuronal ceroid lipofuscinosis 9.5 TMEM11 BNIP3L

Comorbidity relations with Pediculus Humanus Capitis Infestation via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Pediculus Humanus Capitis Infestation:



Diseases related to Pediculus Humanus Capitis Infestation

Symptoms & Phenotypes for Pediculus Humanus Capitis Infestation

Drugs & Therapeutics for Pediculus Humanus Capitis Infestation

Drugs for Pediculus Humanus Capitis Infestation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Malathion Approved, Investigational Phase 2, Phase 3 121-75-5 4004
2
Ivermectin Approved, Investigational, Vet_approved Phase 3 70288-86-7 6474909
3
Permethrin Approved, Investigational Phase 3 52645-53-1 40326
4 Neurotransmitter Agents Phase 3
5 Anti-Infective Agents Phase 3
6 Antiparasitic Agents Phase 3
7 Cholinesterase Inhibitors Phase 3
8 Cholinergic Agents Phase 3
9 Pulmonary Surfactants Phase 3
10 Pharmaceutical Solutions

Interventional clinical trials:

(show all 22)
# Name Status NCT ID Phase Drugs
1 A Randomised, Double-Blind, Multicentre Study to Compare the Efficacy and Tolerability of Oral Ivermectin to Malathion 0.5% Lotion in the Treatment of Head Lice Infestation Completed NCT00819520 Phase 3 ivermectin;malathion
2 A Phase 3 Comparative Safety and Efficacy Study Between NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects > 6 Months of Age With Pediculosis Capitis Completed NCT00545168 Phase 3 Spinosad;Spinosad;Permethrin 1%
3 A Double-Blind Randomized Study to Compare the Efficacy, Safety and Local Tolerability of a 0.5% Ivermectin Cream Compared to a Topical Vehicle Control in Subjects With Pediculus Humanus Capitis Infestation Completed NCT01066585 Phase 3 Ivermectin Cream;vehicle control
4 A Double-Blind Randomized Study to Compare the Efficacy, Safety, and Local Tolerability of a 0.5% Ivermectin Cream Compared to a Topical Vehicle Control in Subjects With Pediculus Humanus Capitis Infestation Completed NCT01068158 Phase 3 0.5% Ivermectin Cream;Placebo control
5 A Phase 3 Comparative Safety and Efficacy Study Between NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects >6 Months of Age or Older With Pediculosis Capitis Completed NCT00545753 Phase 3 Spinosad;Spinosad;Permethrin 1%
6 A Multi-Center Phase III Study to Evaluate MALG, a Novel Malathion 0.05%Formulation, for the Control of Head Lice in Pediatric and Adult Subjects With Pediculosis Capitis Completed NCT00244439 Phase 3 MALG;Ovide (malathion) lotion 0.05%;Permethrin 1%
7 Phase II, Multi-Center, Open-Label, Safety and Tolerance Study of a Novel Malathion Formulation in Infants and Toddlers With Pediculosis Capitis Completed NCT00752973 Phase 2, Phase 3 MALG (malathion) Treatment
8 A Multi-Center Phase III Study to Evaluate Malathion Gel 0.5% Formulation, for the Control of Head Lice in Pediatric Subjects and Adult Subjects With Pediculosis Capitis Completed NCT00963508 Phase 3 Malathion gel 0.5%;Permethrin 1% rinse (Nix Crème)
9 A Multi-Center Phase III Study to Evaluate Ovide Lotion 0.5% Formulation, for the Control of Head Lice in Pediatric Subjects and Adult Subjects With Pediculosis Capitis Completed NCT00927472 Phase 3 Malathion gel 0.5%;Permethrin 1% rinse
10 A Randomised, Controlled, Assessor-blind, Parallel Group Clinical Trial to Assess the Efficacy, Safety and Acceptability of a Surfactant Based Lotion and a Permethrin Creme Rinse in the Treatment of Head Lice Terminated NCT02500524 Phase 3 Cocamide diethanolamine;Permethrin
11 A Double-Blind Randomized Study to Compare the Safety, Local Tolerability and Efficacy of a 0.5% Ivermectin Cream Compared to a Topical Vehicle Control in Subjects With Pediculus Humanus Capitis Infestation Completed NCT00994422 Phase 2 Ivermectin cream;vehicle control
12 Phase 2 Study of Efficacy and Safety of Different Strengths of Spinosad Topical Creme Rinse (0%, 0.5% or 1.0%) in Subjects 2 Years of Age or Older With Pediculosis Capitis - A Dose Ranging Study Completed NCT00311779 Phase 2 Spinosad Creme Rinse
13 Efficacy and Safety of Different Strengths of Spinosad Topical Creme (0%, 0.5%, 1.0% or 2%) in Subjects With Pediculosis Capitis - a Dose Ranging Study Completed NCT00858481 Phase 2 Spinosad Creme Rinse - Vehicle Control;Spinosad Creme Rinse;Spinosad Creme Rinse;Spinosad Creme Rinse
14 A Pilot Study to Test the Operational Elements of an Actual Use Study Designed to Compare the Safety and Efficacy of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months of Age or Older With Pediculosis Capitis Completed NCT00857935 Phase 2 NatrOVA Creme Rinse - 1%;NIX Creme Rinse - 1% permethrin
15 A Randomized, Double-Blind, Placebo-Controlled Clinical Trial On The Efficacy And Safety Of Topical 0.5% Ivermectin Lotion For The Treatment Of Head Lice Infestation Among Filipino Children Age 3 Years Or Older Completed NCT03286101 Phase 2 0.5% Ivermectin lotion;Vehicle
16 Phase II, Multi-center, Open-Label, Safety and Tolerance Study of a Novel Malathion Formulation in Infants and Toddlers With Pediculosis Capitis Terminated NCT00291057 Phase 2 MALG
17 A Randomized, Single-Dose, Parallel Group, Comparative Pharmacokinetic (PK) Study to Evaluate Malathion Gel 0.5% Versus Ovide (Malathion) Lotion 0.5% in Patients With Pediculosis Capitis Completed NCT00927407 Phase 1 Malathion gel 0.5%;Malathion lotion 0.5%
18 A Phase 1B Single Treatment, Pharmacokinetic and Tolerance Study of NatroVA Topical Creme (1%) i Pediatric Subjects 6 to 24 Months of Age Completed NCT00410709 Phase 1 NatrOVA Creme Rinse (1%)
19 Scalp Pruritus Measurement Using Visual Analog Scale and 5-d Itch Scale in Children With Pediculosis Capitis Completed NCT04415034
20 Treatment of Head Lice Infestation Using Novel Ultrasonic Comb Completed NCT02854878
21 A Randomized Sham Controlled Double Blinded Single Site Clinical Trial Evaluating the Efficacy of Resultz Lice and Egg Elimination Kit for the Removal of Human Head Lice and Eggs on Pediatric and Adult Subjects Completed NCT02997904
22 A Comparative Study to Demonstrate the Efficacy and Safety of Licefreee Spray Against Nix 1% Permethrin in Head Lice Infested Individuals Completed NCT01514513 Licefreee Spray;1% permethrin creme rinse

Search NIH Clinical Center for Pediculus Humanus Capitis Infestation

Genetic Tests for Pediculus Humanus Capitis Infestation

Anatomical Context for Pediculus Humanus Capitis Infestation

Publications for Pediculus Humanus Capitis Infestation

Articles related to Pediculus Humanus Capitis Infestation:

(show all 36)
# Title Authors PMID Year
1
Economic Burden Associated with Head Louse (Pediculus humanus capitis) Infestation in Iran. 61
33083302 2020
2
Forecasting head lice (Pediculidae: Pediculus humanus capitis) infestation incidence hotspots based on spatial correlation analysis in Northwest Iran. 61
32158149 2020
3
Effect of a health education program on reduction of pediculosis in school girls at Amphoe Muang, Khon Kaen Province, Thailand. 61
29889851 2018
4
Safety, Efficacy, and Physicochemical Characterization of Tinospora crispa Ointment: A Community-Based Formulation against Pediculus humanus capitis. 61
28877572 2017
5
[Randomised clinical trial to evaluate the efficacy and safety of a new pediculicide made with saponified olive oil in the eradication of Pediculus humanus capitis]. 61
27255407 2017
6
Electron Microscopic Alterations in Pediculus humanus capitis Exposed to Some Pediculicidal Plant Extracts. 61
27658606 2016
7
Treatment of head lice (Pediculus humanus capitis) infestation: is regular combing alone with a special detection comb effective at all levels? 61
25604670 2015
8
[Epidemiological study of Pediculosis in elementary schools of Arica, northern Chile]. 61
25697248 2014
9
Prehistorical Pediculus humanus capitis infestation: quantitative data and low vacuum scanning microscopy. 61
24626412 2014
10
Prevalence of Pediculus humanus capitis infestation among kindergarten children in Bahía Blanca city, Argentina. 61
22752696 2012
11
[Prevalence of head lice in some primary schools in Iğdır province]. 61
22198918 2011
12
[High performance liquid chromatography-validated analytical method for 1% permethrin quantification]. 61
23437540 2011
13
Impact of ivermectin drug combinations on Pediculus humanus capitis infestation in primary schoolchildren of south Indian rural villages. 61
20064176 2009
14
[Clinical and epidemiological study of pediculosis capitis in schoolchildren from Coro, Venezuela]. 61
18271390 2007
15
Pediculus capitis infestation according to sex and social factors in Hamedan-Iran. 61
19090174 2007
16
Rural life, lower socioeconomic status and parasitic infections. 61
17324610 2007
17
Pediculus capitis infestation according to sex and social factors in Hamedan, Iran. 61
17547060 2006
18
Pediculus capitis infestation according to sex and social factors in Argentina. 61
15997320 2005
19
Economic considerations associated with Pediculus humanus capitis infestation. 61
15248004 2004
20
Prevalence of Pediculus capitis infestation among school children of Chinese refugees residing in mountanous areas of northern Thailand. 61
15191220 2004
21
[Prevalence of pediculus humanus capitis infestation in schoolchildren at Despeñaderos, Córdoba Province]. 61
14763432 2003
22
Pediculus humanus capitis infestation in a Shiraz rural area, Iran. 61
17283477 1999
23
Prevalence and treatment of Pediculus capitis infestation among aboriginal school children in northern Taiwan. 61
10330800 1999
24
Pediculosis capitis among urban school children in Ilorin, Nigeria. 61
7807575 1994
25
The head louse in Sierra Leone: an epidemiological study among school children, in the Njala area. 61
1476959 1992
26
Evaluation of efficacy of four pediculicides against head louse (Pediculus capitis) infestation. 61
1377757 1992
27
Chemotherapy of head louse (Pediculus humanus capitis) infestation gamma benzene hexachloride (gamma-BHC) among school children in Szu-Hu District, Yunlin County, Central West Taiwan. 61
1715809 1991
28
Present status of head louse (Pediculus capitis) infestation among school children in Yunlin County, Taiwan. 61
2030521 1991
29
Comparison of pediculicidal and ovicidal effects of two pyrethrin-piperonyl-butoxide agents. 61
3607818 1987
30
[Incidence of Pediculus capitis infestation in the student population of Alcala de Henares]. 61
3826920 1986
31
Prevalence of head louse (Pediculus capitis) infestation among inhabitants of the Niger Delta. 61
4081545 1985
32
Comparative study of DDT, carbaryl (Sevin) and Actellic (pirimiphos-methyl) in the treatment of Pediculus humanus capitis infestation. 61
6405446 1983
33
Resistance of head louse (Pediculus humanus capitis de Geer) to DDT in Malaysia. 61
7080159 1982
34
Epidemiology of Pediculus humanus capitis infestation in Malaysian school children. 61
7258487 1981
35
Pediculus humanus capitis on children in Mahé, Seychelles. 61
7434423 1980
36
The use of D. D. T. for Pediculus capitis infestation in school children. 61
20297460 1947

Variations for Pediculus Humanus Capitis Infestation

Expression for Pediculus Humanus Capitis Infestation

Search GEO for disease gene expression data for Pediculus Humanus Capitis Infestation.

Pathways for Pediculus Humanus Capitis Infestation

GO Terms for Pediculus Humanus Capitis Infestation

Cellular components related to Pediculus Humanus Capitis Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrion GO:0005739 9.56 TMEM11 MT-CYB COX18 BNIP3L
2 mitochondrial inner membrane GO:0005743 9.33 TMEM11 MT-CYB COX18
3 intrinsic component of membrane GO:0031224 8.96 MT-CYB BNIP3L
4 integral component of mitochondrial inner membrane GO:0031305 8.8 TMEM11 MT-CYB COX18

Biological processes related to Pediculus Humanus Capitis Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of macroautophagy GO:0016239 8.62 KDR BNIP3L

Sources for Pediculus Humanus Capitis Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....