MCID: PDC003
MIFTS: 22

Pediculus Humanus Corporis Infestation

Categories: Infectious diseases

Aliases & Classifications for Pediculus Humanus Corporis Infestation

MalaCards integrated aliases for Pediculus Humanus Corporis Infestation:

Name: Pediculus Humanus Corporis Infestation 12 15
Body Louse Infestation 12 71
Pediculus Humanus Infestation 12
Pediculus Corporis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5513
ICD9CM 34 132.1
SNOMED-CT 67 25188002
ICD10 32 B85.1
UMLS 71 C0030758

Summaries for Pediculus Humanus Corporis Infestation

Disease Ontology : 12 A lice infestation that is a cutaneous condition caused by parasitic infestation of body lice Pediculus humanus corporis, which feed on the human blood. Body lice can spread epidemic typhus, trench fever, and louse-borne relapsing fever.

MalaCards based summary : Pediculus Humanus Corporis Infestation, also known as body louse infestation, is related to epidemic typhus and carrion's disease. An important gene associated with Pediculus Humanus Corporis Infestation is AFF2 (AF4/FMR2 Family Member 2). Affiliated tissues include skin and pancreas.

Related Diseases for Pediculus Humanus Corporis Infestation

Diseases related to Pediculus Humanus Corporis Infestation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Related Disease Score Top Affiliating Genes
1 epidemic typhus 29.0 WARS1 TXNDC15 PPP1R14A MT-CYB CS CD40LG
2 carrion's disease 10.3 WARS1 PPP1R14A MT-CYB
3 relapsing fever 10.3
4 flinders island spotted fever 10.3 LINC01554 CS AFF2
5 trench fever 10.3 WARS1 MT-CYB CS
6 bacillary angiomatosis 10.3 WARS1 PPP1R14A CS
7 myiasis 10.1 MT-CYB MT-CO1
8 endemic typhus 10.1 WARS1 PPP1R14A CS AFF2
9 mitochondrial myopathy, infantile, transient 10.1 MT-CYB MT-CO1
10 mitochondrial non-syndromic sensorineural deafness 10.1 MT-ND4 MT-CO1
11 myasthenic syndrome, congenital, 10 10.1 MT-CYB MT-CO1 LINC01554
12 angiostrongyliasis 10.0 MT-CYB MT-CO1
13 lice infestation 10.0 TXNDC15 MT-CYB MT-CO1
14 parasitic ectoparasitic infectious disease 10.0 TXNDC15 MT-CYB MT-CO1
15 sparganosis 10.0 MT-ND4 MT-CYB MT-CO1
16 pearson marrow-pancreas syndrome 10.0 MT-ND4 MT-CYB
17 plasmodium malariae malaria 10.0 MT-CYB CD40LG
18 phlebotomus fever 9.9 MT-CYB CD40LG
19 alkhurma hemorrhagic fever 9.9 TXNDC15 CD40LG
20 brill-zinsser disease 9.9 WARS1 CD40LG AFF2
21 retinitis pigmentosa 48 9.9 LINC01554 CD40LG
22 indian tick typhus 9.9 PPP1R14A CD40LG AFF2
23 japanese spotted fever 9.9 PPP1R14A CD40LG AFF2
24 pediculus humanus capitis infestation 9.9 TXNDC15 TMEM11 MT-CYB MT-CO1
25 neuroretinitis 9.9 CS CD40LG
26 polycystic echinococcosis 9.9 MT-CO1 CXCL11
27 hantavirus pulmonary syndrome 9.8 MT-CYB CD40LG
28 cat-scratch disease 9.8 PPP1R14A CS CD40LG
29 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 9.7 MT-ND4 MT-CYB MT-CO1 CS
30 mitochondrial myopathy 9.7 MT-ND4 MT-CYB MT-CO1 CS
31 leber optic atrophy 9.7 MT-ND4 MT-CYB MT-CO1 CS
32 kearns-sayre syndrome 9.7 MT-ND4 MT-CYB MT-CO1 CS
33 cranial nerve disease 9.7 MT-ND4 MT-CYB CD40LG
34 amelogenesis imperfecta, type iv 9.7 MT-CYB MT-CO1
35 hantavirus hemorrhagic fever with renal syndrome 9.7 MX2 MX1 CD40LG
36 mitochondrial metabolism disease 9.7 MT-ND4 MT-CYB MT-CO1 CS
37 rocky mountain spotted fever 9.7 PPP1R14A CS CD40LG AFF2
38 spotted fever 9.7 PPP1R14A CS CD40LG AFF2
39 boutonneuse fever 9.7 PPP1R14A CS CD40LG AFF2
40 transient hypogammaglobulinemia of infancy 9.6 CD40LG CD27
41 3-methylglutaconic aciduria, type iii 9.6 MT-ND4 MT-CYB MT-CO1 CS
42 immunodeficiency with hyper-igm, type 4 9.6 CD40LG CD27
43 babesiosis 9.6 MT-CYB MT-CO1 CD40LG
44 chronic meningitis 9.6 MT-CO1 CD40LG
45 optic nerve disease 9.6 MT-ND4 MT-CYB CD40LG
46 mite infestation 9.6 TXNDC15 MT-CO1 CD40LG
47 bartonellosis 9.5 WARS1 PPP1R14A MT-CYB CS CD40LG
48 taeniasis 9.5 MT-CO1 CD40LG
49 parasitic protozoa infectious disease 9.4 TXNDC15 MT-CYB MT-CO1 CD40LG
50 congenital myasthenic syndrome 9.3 TXNDC15 MT-CYB MT-CO1 LINC01554 CD40LG

Graphical network of the top 20 diseases related to Pediculus Humanus Corporis Infestation:



Diseases related to Pediculus Humanus Corporis Infestation

Symptoms & Phenotypes for Pediculus Humanus Corporis Infestation

Drugs & Therapeutics for Pediculus Humanus Corporis Infestation

Search Clinical Trials , NIH Clinical Center for Pediculus Humanus Corporis Infestation

Genetic Tests for Pediculus Humanus Corporis Infestation

Anatomical Context for Pediculus Humanus Corporis Infestation

MalaCards organs/tissues related to Pediculus Humanus Corporis Infestation:

40
Skin, Pancreas

Publications for Pediculus Humanus Corporis Infestation

Articles related to Pediculus Humanus Corporis Infestation:

# Title Authors PMID Year
1
Preventing and controlling emerging and reemerging transmissible diseases in the homeless. 61
18760000 2008
2
Oral ivermectin in the treatment of body lice. 61
16388498 2006
3
Prevalence of skin infections in sheltered homeless. 61
16172049 2005
4
[Lice and lice-borne diseases in humans]. 61
15903070 2005
5
Outbreak of epidemic typhus associated with trench fever in Burundi. 61
9717922 1998
6
Pediculosis. 61
1693887 1990
7
[Body-louse infestation in patient with typhus as a source of new infections]. 61
13245868 1955

Variations for Pediculus Humanus Corporis Infestation

Expression for Pediculus Humanus Corporis Infestation

Search GEO for disease gene expression data for Pediculus Humanus Corporis Infestation.

Pathways for Pediculus Humanus Corporis Infestation

GO Terms for Pediculus Humanus Corporis Infestation

Cellular components related to Pediculus Humanus Corporis Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 postsynaptic density GO:0014069 9.62 RPS13 MX2 MX1 MAPK1
2 mitochondrial respiratory chain complex III GO:0005750 9.26 MT-CYB MT-CO1
3 dendritic spine head GO:0044327 9.16 MX2 MX1
4 respiratory chain GO:0070469 9.13 MT-ND4 MT-CYB MT-CO1
5 postsynaptic endocytic zone membrane GO:0098844 8.62 MX2 MX1

Biological processes related to Pediculus Humanus Corporis Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to ethanol GO:0045471 9.58 MT-ND4 MT-CYB CD27
2 mitochondrial fission GO:0000266 9.43 MX2 MX1
3 response to copper ion GO:0046688 9.37 MT-CYB MT-CO1
4 regulation of synapse structure or activity GO:0050803 9.32 MX2 MX1
5 postsynaptic neurotransmitter receptor internalization GO:0098884 9.26 MX2 MX1
6 aging GO:0007568 9.26 MT-ND4 MT-CO1 MAPK1 FOXG1
7 synaptic vesicle budding from presynaptic endocytic zone membrane GO:0016185 9.16 MX2 MX1
8 electron transport coupled proton transport GO:0015990 8.8 MT-ND4 MT-CYB MT-CO1

Sources for Pediculus Humanus Corporis Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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