MCID: PDP001
MIFTS: 33

Pedophilia

Categories: Mental diseases

Aliases & Classifications for Pedophilia

MalaCards integrated aliases for Pedophilia:

Name: Pedophilia 12 45 15 74
Paedophilia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13351
ICD9CM 36 302.2
MeSH 45 D010378
NCIt 51 C94355
SNOMED-CT 69 84002002
ICD10 34 F65.4
UMLS 74 C0030764

Summaries for Pedophilia

MalaCards based summary : Pedophilia, also known as paedophilia, is related to androgenic alopecia and brain injury. An important gene associated with Pedophilia is PRL (Prolactin). The drugs Leuprolide and Cyproterone Acetate have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye, and related phenotype is nervous system.

Wikipedia : 77 Pedophilia (alternatively spelt paedophilia) is a psychiatric disorder in which an adult or older... more...

Related Diseases for Pedophilia

Graphical network of the top 20 diseases related to Pedophilia:



Diseases related to Pedophilia

Symptoms & Phenotypes for Pedophilia

MGI Mouse Phenotypes related to Pedophilia:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.1 GRN IFNB1 OXT PRL RTN4 TWIST1

Drugs & Therapeutics for Pedophilia

Drugs for Pedophilia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Leuprolide Approved, Investigational Phase 2, Phase 3,Phase 3 53714-56-0 657181 3911
2
Cyproterone Acetate Approved, Investigational Phase 3 427-51-0
3 Antineoplastic Agents, Hormonal Phase 2, Phase 3
4 Fertility Agents Phase 2, Phase 3
5 Hormone Antagonists Phase 3
6 Androgens Phase 3
7
Cyproterone Phase 3 2098-66-0 5284537
8 Contraceptive Agents Phase 3
9 Hormones Phase 3
10 Contraceptive Agents, Male Phase 3
11 Androgen Antagonists Phase 3
12 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Impaired Decision Making in Pedophilic Offenders Unknown status NCT01541150 Phase 4
2 Lupron Sex Offender Therapy Unknown status NCT00220350 Phase 2, Phase 3 leuprolide acetate
3 Comparison of Two Pharmacological Treatments of Pedophilia Terminated NCT00601276 Phase 3 leuprorelin;Cyproterone acetate
4 Analysis of Cerebral Correlates of Pedophilia With Neuroimaging Techniques Completed NCT02822664 Not Applicable
5 From Attention to Behavior: Increasing Behavioral Inhibition Not yet recruiting NCT03825627 Not Applicable

Search NIH Clinical Center for Pedophilia

Cochrane evidence based reviews: pedophilia

Genetic Tests for Pedophilia

Anatomical Context for Pedophilia

MalaCards organs/tissues related to Pedophilia:

42
Brain, Testes, Eye, Amygdala, Skin, Cerebellum, Cortex

Publications for Pedophilia

Articles related to Pedophilia:

(show top 50) (show all 172)
# Title Authors Year
1
Are There Early Risk Markers for Pedophilia? A Nationwide Case-Control Study of Child Sexual Exploitation Material Offenders. ( 30064261 )
2019
2
The Neurobiological Origins of Pedophilia: Not That Simple. ( 30621922 )
2019
3
Empathy in pedophilia and sexual offending against children: A multifaceted approach. ( 31045397 )
2019
4
Pedophilia-Themed Obsessive-Compulsive Disorder: Assessment, Differential Diagnosis, and Treatment with Exposure and Response Prevention. ( 28822003 )
2018
5
GnRH Antagonist and Antipsychotic Medication for Pedophilia Comorbid with Schizophrenia and Intellectual Disability. ( 29938360 )
2018
6
Therapists' Experiences in Their Work With Sex Offenders and People With Pedophilia: A Literature Review. ( 30008959 )
2018
7
Mental Insanity Assessment of Pedophilia: The Importance of the Trans-Disciplinary Approach. Reflections on Two Cases. ( 29867338 )
2018
8
Toward a Neurodevelopmental Understanding of Pedophilia. ( 29861362 )
2018
9
Paraphilic infantilism, diaperism and pedophilia: A review. ( 29525580 )
2018
10
Is Contact with Children Related to Legitimizing Beliefs Toward Sex with Children Among Men with Pedophilia? ( 29330640 )
2018
11
Emotions and Cognitions Associated with the Stigma of Non-Offending Pedophilia: A Vignette Experiment. ( 29159755 )
2018
12
Determinants of Punitive Attitudes Toward People with Pedophilia: Dissecting Effects of the Label and Intentionality Ascriptions. ( 28799101 )
2018
13
Why Information Matters: Examining the Consequences of Suggesting That Pedophilia Is Immutable. ( 27864530 )
2018
14
Clinical characteristics associated with paedophilia and child sex offending - Differentiating sexual preference from offence status. ( 29625377 )
2018
15
Decoding Pedophilia: Increased Anterior Insula Response to Infant Animal Pictures. ( 29403367 )
2017
16
Taxometric analyses of pedophilia utilizing self-report, behavioral, and sexual arousal indicators. ( 29154571 )
2017
17
Neural correlates of moral judgment in pedophilia. ( 28992273 )
2017
18
Executive Functioning in Pedophilia and Child Sexual Offending. ( 28511726 )
2017
19
Leg Length Versus Torso Length in Pedophilia: Further Evidence of Atypical Physical Development Early in Life. ( 26459491 )
2017
20
Reliability and validity of the DSM-IV-TR and proposed DSM-5 criteria for pedophilia: Implications for the ICD-11 and the next DSM. ( 27665026 )
2016
21
Neural basis of pedophilia: Altered sexual preference following traumatic brain injury. ( 27394398 )
2016
22
Assessing paedophilia based on the haemodynamic brain response to face images. ( 26452682 )
2016
23
Researchers use crowdfunding site to raise money to test potential paedophilia treatment. ( 27055461 )
2016
24
Diffusion Tensor Imaging of Pedophilia. ( 26494360 )
2015
25
Androgen deprivation therapy (castration therapy) and pedophilia: What's new. ( 26428645 )
2015
26
A Temporal Link Between Epileptiform Brain Activity, Schizotypy, and Pedophilia. ( 26222969 )
2015
27
The Neurobiology and Psychology of Pedophilia: Recent Advances and Challenges. ( 26157372 )
2015
28
Minor Physical Anomalies as a Window into the Prenatal Origins of Pedophilia. ( 26058490 )
2015
29
Connectivity and functional profiling of abnormal brain structures in pedophilia. ( 25733379 )
2015
30
Commentary on Kärgel and colleagues' study: diminished functional connectivity on the road to child sexual abuse in pedophilia. ( 25683865 )
2015
31
Diminished functional connectivity on the road to child sexual abuse in pedophilia. ( 25615561 )
2015
32
Pedophilia 30 years after a traumatic brain injury. ( 25098556 )
2015
33
Stigmatizing attitudes towards people with pedophilia and their malleability among psychotherapists in training. ( 25085206 )
2015
34
Purported changes in pedophilia as statistical artefacts: comment on Müller et Al. (2014). ( 25048080 )
2015
35
Stigmatization of people with pedophilia: two comparative surveys. ( 24948422 )
2015
36
Rethinking responsibility in offenders with acquired paedophilia: punishment or treatment? ( 25725545 )
2015
37
Paedophilia, Invasive Brain Surgery, and Punishment. ( 26173776 )
2015
38
Potential implications of research on genetic or heritable contributions to pedophilia for the objectives of criminal law. ( 25557668 )
2014
39
Pedophilia and DSM-5: the importance of clearly defining the nature of a Pedophilic Disorder. ( 25492064 )
2014
40
Changed processing of visual sexual stimuli under GnRH-therapy--a single case study in pedophilia using eye tracking and fMRI. ( 24885644 )
2014
41
Elevated rates of atypical handedness in paedophilia: theory and implications. ( 24666135 )
2014
42
Brain alterations in paedophilia: a critical review. ( 25116710 )
2014
43
Association between brain structure and phenotypic characteristics in pedophilia. ( 23399486 )
2013
44
Neuroimaging in pedophilia. ( 23435970 )
2013
45
Response inhibition in pedophilia: an FMRI pilot study. ( 24247250 )
2013
46
Pedophilia: is there a duty to report? ( 24152773 )
2013
47
Is "pedophilia" a paraphrase of the incest taboo? Apropos: are the corollaries of taboo offered up as reasons for it? ( 23771551 )
2013
48
Immediate processing of erotic stimuli in paedophilia and controls: a case control study. ( 23510246 )
2013
49
A pilot study of the effects of gonadotropin-releasing hormone agonist therapy on brain activation pattern in a man with pedophilia. ( 21518701 )
2012
50
Assessment of pedophilia using hemodynamic brain response to sexual stimuli. ( 21969422 )
2012

Variations for Pedophilia

Expression for Pedophilia

Search GEO for disease gene expression data for Pedophilia.

Pathways for Pedophilia

GO Terms for Pedophilia

Biological processes related to Pedophilia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 female pregnancy GO:0007565 9.16 OXT PRL
2 regulation of signaling receptor activity GO:0010469 8.92 GRN IFNB1 OXT PRL
3 positive regulation of epithelial cell proliferation GO:0050679 8.65 TWIST1

Sources for Pedophilia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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