MCID: PLS002
MIFTS: 37

Peliosis Hepatis

Categories: Cardiovascular diseases, Endocrine diseases, Gastrointestinal diseases, Immune diseases, Liver diseases

Aliases & Classifications for Peliosis Hepatis

MalaCards integrated aliases for Peliosis Hepatis:

Name: Peliosis Hepatis 12 44 15 73
Hepatic Peliosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:914
ICD10 33 K76.4
MeSH 44 D010382
SNOMED-CT 68 58008004
UMLS 73 C0030781

Summaries for Peliosis Hepatis

MalaCards based summary : Peliosis Hepatis, also known as hepatic peliosis, is related to idiopathic peliosis hepatis and bartonellosis. An important gene associated with Peliosis Hepatis is THOC2 (THO Complex 2), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and G-protein signaling_Rap2B regulation pathway. Affiliated tissues include liver, lymph node and kidney, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 76 Peliosis hepatis is an uncommon vascular condition characterised by multiple, randomly distributed,... more...

Related Diseases for Peliosis Hepatis

Diseases related to Peliosis Hepatis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 idiopathic peliosis hepatis 12.5
2 bartonellosis 11.4
3 nodular regenerative hyperplasia 10.4
4 portal hypertension 10.3
5 myopathy 10.3
6 hepatocellular carcinoma 10.2
7 systemic lupus erythematosus 10.2
8 myopathy, centronuclear, x-linked 10.2
9 aplastic anemia 10.2
10 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 10.2
11 hepatitis 10.2
12 hepatitis b 10.2
13 liver disease 10.2
14 lymphoma 10.2
15 bacillary angiomatosis 10.2
16 acquired immunodeficiency syndrome 10.2
17 lupus erythematosus 10.2
18 macroglobulinemia 10.2
19 viral infectious disease 10.2
20 endometrial small cell carcinoma 10.2 AFP F2
21 vitamin k deficiency hemorrhagic disease 10.1 AFP F2
22 long-chain 3-hydroxyacyl-coa dehydrogenase deficiency 10.1 HADHA VIM
23 hepatic tuberculosis 10.1 F2 SMUG1
24 eccrine adenocarcinoma 10.1 F2 SMUG1
25 venous insufficiency 10.1 F2 ITGA4 SELL
26 adenomatoid tumor 10.1 AFP VIM
27 hepatic infarction 10.1 F2 HADHA
28 pancreatic cholera 10.1 GHRH MEN1
29 ischemic colitis 10.1 F2 VEGFA
30 intravascular papillary endothelial hyperplasia 10.1 VEGFA VIM
31 esophageal varix 10.1 AFP F2
32 renal cell carcinoma, nonpapillary 10.1
33 prostate cancer 10.1
34 thrombocytopenic purpura, autoimmune 10.1
35 myeloma, multiple 10.1
36 aging 10.1
37 myelodysplastic syndrome 10.1
38 deficiency anemia 10.1
39 crohn's disease 10.1
40 glycogen storage disease 10.1
41 hemangioma 10.1
42 hepatocellular adenoma 10.1
43 castleman disease 10.1
44 endocarditis 10.1
45 gastric ulcer 10.1
46 disseminated intravascular coagulation 10.1
47 iron deficiency anemia 10.1
48 marasmus 10.1
49 cholestasis 10.1
50 iron metabolism disease 10.1

Graphical network of the top 20 diseases related to Peliosis Hepatis:



Diseases related to Peliosis Hepatis

Symptoms & Phenotypes for Peliosis Hepatis

MGI Mouse Phenotypes related to Peliosis Hepatis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.9 AFP COL14A1 COL18A1 F2 GHRH HADHA
2 cardiovascular system MP:0005385 9.86 COL18A1 F2 HADHA ITGA4 MEN1 SELL
3 liver/biliary system MP:0005370 9.43 AFP GHRH HADHA MEN1 SELL VEGFA
4 neoplasm MP:0002006 9.1 AFP COL18A1 MEN1 SELL SMUG1 VEGFA

Drugs & Therapeutics for Peliosis Hepatis

Search Clinical Trials , NIH Clinical Center for Peliosis Hepatis

Cochrane evidence based reviews: peliosis hepatis

Genetic Tests for Peliosis Hepatis

Anatomical Context for Peliosis Hepatis

MalaCards organs/tissues related to Peliosis Hepatis:

41
Liver, Lymph Node, Kidney, Bone, Spleen, Lung, Adrenal Gland

Publications for Peliosis Hepatis

Articles related to Peliosis Hepatis:

(show top 50) (show all 197)
# Title Authors Year
1
Peliosis Hepatis Simulating Metastatic Liver Disease on FDG PET/CT. ( 29659400 )
2018
2
Peliosis hepatis and systemic lupus erythematosus: A rare condition identified by magnetic resonance imaging. ( 29561938 )
2018
3
Peliosis Hepatis Simulates Liver Metastases. ( 30241218 )
2018
4
Liver lesions detected in a hepatitis B core total antibody-positive patient masquerading as hepatocellular carcinoma: a rare case of peliosis hepatis and a review of the literature. ( 28990003 )
2017
5
Peliosis hepatis: 2 case reports of a rare liver disorder and its differential diagnosis. ( 28353584 )
2017
6
A Fatal Case of Intra-Abdominal Hemorrhage Following Diagnostic Blind Percutaneous Liver Biopsy in a Patient With Peliosis Hepatis. ( 29118875 )
2017
7
Contrast enhanced ultrasound of a rare case of Peliosis hepatis. ( 28180205 )
2017
8
Peliosis Hepatis Complicating Pregnancy: A Rare Entity. ( 28721347 )
2017
9
Hepatobiliary and Pancreatic: Focal peliosis hepatis mimicking hepatocellular carcinoma in a hepatitis B carrier. ( 26600454 )
2016
10
Resolution of spontaneous hemoabdomen secondary to peliosis hepatis following surgery and azithromycin treatment in a Bartonella species infected dog. ( 27074964 )
2016
11
Peliosis Hepatis Mimicking Malignant Hypervascular Tumors. ( 27783341 )
2016
12
Danazol-induced peliosis hepatis accompanied by disseminated intravascular coagulation in a patient with myelodysplastic syndrome transformed from aplastic anemia. ( 27599419 )
2016
13
Peliosis hepatis: Personal experience and literature review. ( 26675327 )
2015
14
Generalised peliosis hepatis mimicking metastases after long-term use of oral contraceptives. ( 26219941 )
2015
15
Spontaneous hepatic rupture during pregnancy in a patient with peliosis hepatis. ( 26019044 )
2015
16
Focal type of peliosis hepatis. ( 26770930 )
2015
17
Peliosis hepatis disseminated rapidly throughout the liver in a patient with prostate cancer: a case report. ( 26362063 )
2015
18
Peliosis hepatis presenting with massive hepatomegaly in a patient with idiopathic thrombocytopenic purpura. ( 26770928 )
2015
19
Giant hepatocellular adenoma with peliosis hepatis in a child: A diagnostic dilemma. ( 27522744 )
2015
20
A case of intra-abdominal hemorrhage secondary to peliosis hepatis. ( 25576958 )
2015
21
Peliosis Hepatis Shows Isometabolism on (18)F-FDG PET/CT: Two Case Reports. ( 26396637 )
2014
22
Peliosis hepatis: one pathology, a thousand faces, and a clinical and radiological diagnostic challenge. ( 24528847 )
2014
23
Hepatobiliary and Pancreatic: Peliosis hepatis associated with multiple myeloma. ( 24354992 )
2014
24
Multifocal peliosis hepatis simulating metastatic malignancy. ( 24890622 )
2014
25
Hepatobiliary and Pancreatic: Spontaneous intrahepatic hemorrhage from peliosis hepatis-An uncommon complication of a rare liver disorder. ( 25318383 )
2014
26
Peliosis hepatis complicated by portal hypertension following renal transplantation. ( 24605041 )
2014
27
Peliosis hepatis in a kidney transplant recipient with manifestation as massive ascites and liver dysfunction: case report. ( 24656031 )
2014
28
Spontaneous hepatic rupture in a patient with peliosis hepatis: A report of one case. ( 23562904 )
2013
29
Surgical treatment of a patient with peliosis hepatis: a case report. ( 23674863 )
2013
30
Peliosis hepatis due to disseminated tuberculosis in a patient with AIDS. ( 23765512 )
2013
31
Peliosis hepatis mimicking cancer: A case report. ( 24137445 )
2013
32
Peliosis hepatis in a child with myotubular myopathy: successful treatment using hepatic artery embolization. ( 23932635 )
2013
33
Ruptured liver caused by peliosis hepatis. ( 24314607 )
2013
34
Fatal Hepatic Hemorrhage from Peliosis Hepatis with X-linked Myotubular Myopathy: A Case Report. ( 24172586 )
2013
35
Peliosis hepatis mimicking hepatic malignancy: a case report. ( 23297820 )
2013
36
Peliosis hepatis: a complicating finding in a case of biliary colic. ( 24072833 )
2013
37
Fatal hepatic hemorrhage by peliosis hepatis in X-linked myotubular myopathy: a case report. ( 24011703 )
2013
38
Peliosis hepatis associated with hereditary haemorrhagic telangiectasia. ( 24759967 )
2013
39
Peliosis hepatis presenting as liver rupture in a vulnerable adult: a case report. ( 22104329 )
2012
40
Focal peliosis hepatis in a colon cancer patient resembling metastatic liver tumor. ( 23139621 )
2012
41
Liver hemorrhage due to idiopathic peliosis hepatis successfully treated with hepatic artery embolization. ( 22808612 )
2011
42
Education and imaging. Hepatobiliary and pancreatic: peliosis hepatis. ( 21564290 )
2011
43
Peliosis hepatis in cats is not associated with Bartonella henselae infections. ( 20080497 )
2010
44
Multifocal peliosis hepatis: MR and diffusion-weighted MR-imaging findings of an atypical case. ( 20095924 )
2010
45
Peliosis hepatis in cancer patients mimicking infection and metastases. ( 19209022 )
2009
46
Spontaneous liver rupture in a patient with peliosis hepatis: a case report. ( 19916182 )
2009
47
Congenital portal vein aneurysm associated with peliosis hepatis and intestinal lymphangiectasia. ( 20368998 )
2009
48
First reported case of disease: peliosis hepatis as cardinal symptom of Hodgkin's lymphoma. ( 19889716 )
2009
49
Peliosis hepatis presenting as hemoperitoneum. ( 18603741 )
2008
50
Focal peliosis hepatis as a mimicker of hepatic tumors: radiological-pathological correlation. ( 17259837 )
2007

Variations for Peliosis Hepatis

Expression for Peliosis Hepatis

Search GEO for disease gene expression data for Peliosis Hepatis.

Pathways for Peliosis Hepatis

Pathways related to Peliosis Hepatis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.26 AFP VEGFA VIM
2 9.92 COL14A1 COL18A1 GHRH ITGA4 VIM

GO Terms for Peliosis Hepatis

Cellular components related to Peliosis Hepatis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 AFP COL14A1 COL18A1 F2 GHRH SERPINA7
2 extracellular region GO:0005576 9.56 AFP APEH COL14A1 COL18A1 F2 GHRH
3 endoplasmic reticulum lumen GO:0005788 9.02 AFP COL14A1 COL18A1 F2 MEN1

Biological processes related to Peliosis Hepatis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of collagen biosynthetic process GO:0032967 9.26 F2 VIM
2 positive regulation of endothelial cell apoptotic process GO:2000353 9.16 COL18A1 ITGA4
3 leukocyte tethering or rolling GO:0050901 8.96 ITGA4 SELL
4 positive regulation of leukocyte migration GO:0002687 8.62 ITGA4 VEGFA

Molecular functions related to Peliosis Hepatis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 fibronectin binding GO:0001968 8.96 ITGA4 VEGFA
2 heparin binding GO:0008201 8.8 F2 SELL VEGFA

Sources for Peliosis Hepatis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....