MCID: PLS002
MIFTS: 37

Peliosis Hepatis

Categories: Cardiovascular diseases, Endocrine diseases, Gastrointestinal diseases, Immune diseases, Liver diseases

Aliases & Classifications for Peliosis Hepatis

MalaCards integrated aliases for Peliosis Hepatis:

Name: Peliosis Hepatis 12 44 15 17 72 33
Hepatic Peliosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:914
MeSH 44 D010382
SNOMED-CT 68 58008004
ICD10 33 K76.4
UMLS 72 C0030781

Summaries for Peliosis Hepatis

MalaCards based summary : Peliosis Hepatis, also known as hepatic peliosis, is related to portal hypertension and hepatic coma. An important gene associated with Peliosis Hepatis is THOC2 (THO Complex 2), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins. Affiliated tissues include liver, kidney and spleen, and related phenotypes are homeostasis/metabolism and neoplasm

Wikipedia : 75 Peliosis hepatis is an uncommon vascular condition characterised by multiple, randomly distributed,... more...

Related Diseases for Peliosis Hepatis

Diseases related to Peliosis Hepatis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 155)
# Related Disease Score Top Affiliating Genes
1 portal hypertension 31.0 VEGFA GPT F2
2 hepatic coma 30.6 GPT F2
3 viral hepatitis 30.3 GPT F2 AFP
4 idiopathic peliosis hepatis 12.7
5 bartonellosis 11.9
6 hepatoportal sclerosis 10.6 GPT F2
7 liver disease 10.5
8 primary hepatic neuroendocrine carcinoma 10.5 VIM GPT
9 aplastic anemia 10.5
10 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 10.5
11 myopathy 10.5
12 hepatic tuberculosis 10.4 GPT F2
13 immune deficiency disease 10.4
14 adenoma 10.4
15 nodular regenerative hyperplasia 10.4
16 kwashiorkor 10.4 GPT F2
17 hepatocellular carcinoma 10.4
18 systemic lupus erythematosus 10.4
19 bacillary angiomatosis 10.4
20 cholestasis 10.4
21 acquired immunodeficiency syndrome 10.4
22 angiomatosis 10.4
23 fanconi anemia, complementation group a 10.3
24 angiosarcoma 10.3
25 hepatorenal syndrome 10.3
26 lupus erythematosus 10.3
27 sternum cancer 10.3 VIM AFP
28 endometrial small cell carcinoma 10.3 F2 AFP
29 venous insufficiency 10.3 SELL ITGA4 F2
30 intravascular papillary endothelial hyperplasia 10.3 VIM VEGFA
31 deficiency anemia 10.2
32 castleman disease 10.2
33 endocarditis 10.2
34 pyelonephritis 10.2
35 thrombocytopenia 10.2
36 pneumothorax 10.2
37 hemangioma 10.2
38 pulmonary tuberculosis 10.2
39 chronic wasting disease 10.2
40 liver cirrhosis 10.2
41 macroglobulinemia 10.2
42 47,xyy 10.2
43 hypotonia 10.2
44 infantile liver failure syndrome 1 10.2 GPT F2
45 adenomatoid tumor 10.2 VIM AFP
46 ischemic colitis 10.2 VEGFA F2
47 opisthorchiasis 10.2 GPT AFP
48 bile duct disease 10.2 GPT F2 AFP
49 human immunodeficiency virus type 1 10.1
50 hepatitis a 10.1 GPT F2 AFP

Graphical network of the top 20 diseases related to Peliosis Hepatis:



Diseases related to Peliosis Hepatis

Symptoms & Phenotypes for Peliosis Hepatis

MGI Mouse Phenotypes related to Peliosis Hepatis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.7 AFP CD4 COL18A1 F2 FN1 GHRH
2 neoplasm MP:0002006 9.1 AFP COL18A1 FN1 MEN1 SELL VEGFA

Drugs & Therapeutics for Peliosis Hepatis

Search Clinical Trials , NIH Clinical Center for Peliosis Hepatis

Cochrane evidence based reviews: peliosis hepatis

Genetic Tests for Peliosis Hepatis

Anatomical Context for Peliosis Hepatis

MalaCards organs/tissues related to Peliosis Hepatis:

41
Liver, Kidney, Spleen, Lung, Lymph Node, Bone, Adrenal Gland

Publications for Peliosis Hepatis

Articles related to Peliosis Hepatis:

(show top 50) (show all 456)
# Title Authors PMID Year
1
Hepatic disorders associated with exogenous sex steroids: MR imaging findings. 38
30955069 2019
2
Peliosis Hepatis due to Corticosteroid in Systemic Lupus Erythematosus. 38
30713305 2019
3
An autopsy case of peliosis hepatis with X-linked myotubular myopathy. 38
31030121 2019
4
Liver haematoma as a presentation of peliosis hepatis. 38
30798271 2019
5
[Magnetic resonance imaging and diffusion weighted imaging features of focal peliosis hepatis]. 38
30786345 2019
6
Bartonella infections in cats and dogs including zoonotic aspects. 38
30514361 2018
7
Peliosis Hepatis Simulates Liver Metastases. 38
30241218 2018
8
Cat-Scratch Disease in an AIDS Patient Presenting with Generalized Lymphadenopathy: An Unusual Presentation with Delayed Diagnosis. 38
30068900 2018
9
Peliosis Hepatis Simulating Metastatic Liver Disease on FDG PET/CT. 38
29659400 2018
10
Isolated hepatic non-obstructive sinusoidal dilatation, 20-year single center experience. 38
29844855 2018
11
Spontaneous hepatic rupture in a bodybuilder: a case report and review of the literature. 38
29313696 2018
12
Peliosis hepatis associated with follicular lymphoma with a rise in vascular endothelial growth factor and anaemia of inflammation. 38
30679949 2018
13
Peliosis hepatis and systemic lupus erythematosus: A rare condition identified by magnetic resonance imaging. 38
29561938 2018
14
A Fatal Case of Intra-Abdominal Hemorrhage Following Diagnostic Blind Percutaneous Liver Biopsy in a Patient With Peliosis Hepatis. 38
29118875 2017
15
Liver lesions detected in a hepatitis B core total antibody-positive patient masquerading as hepatocellular carcinoma: a rare case of peliosis hepatis and a review of the literature. 38
28990003 2017
16
Peliosis Hepatis Mimicking Malignant Hypervascular Tumors. 38
27783341 2017
17
Peliosis Hepatis Complicating Pregnancy: A Rare Entity. 38
28721347 2017
18
A Comprehensive Approach to Hepatic Vascular Disease. 38
28430541 2017
19
Hepatotoxicity associated with illicit use of anabolic androgenic steroids in doping. 38
28379599 2017
20
Peliosis hepatis: 2 case reports of a rare liver disorder and its differential diagnosis. 38
28353584 2017
21
Contrast enhanced ultrasound of a rare case of Peliosis hepatis. 38
28180205 2017
22
Resolution of spontaneous hemoabdomen secondary to peliosis hepatis following surgery and azithromycin treatment in a Bartonella species infected dog. 38
27074964 2016
23
The centenary of the discovery of trench fever, an emerging infectious disease of World War 1. 38
27375211 2016
24
Anabolic androgenic steroid-induced hepatotoxicity. 38
27372877 2016
25
Danazol-induced peliosis hepatis accompanied by disseminated intravascular coagulation in a patient with myelodysplastic syndrome transformed from aplastic anemia. 38
27599419 2016
26
Hepatobiliary and Pancreatic: Focal peliosis hepatis mimicking hepatocellular carcinoma in a hepatitis B carrier. 38
26600454 2016
27
An Autopsy Case of Spontaneous Splenic Rupture Due to Isolated Splenic Peliosis and Review of the Literature. 38
31239904 2016
28
Enzymatic and histopathologic biomarkers in the flatfish Euryglossa orientalis from the northwestern Persian Gulf. 38
24334611 2016
29
Oxaliplatin-induced sinusoidal obstruction syndrome mimicking metastatic colon cancer in the liver. 38
27073565 2016
30
Peliosis hepatis presenting with massive hepatomegaly in a patient with idiopathic thrombocytopenic purpura. 38
26770928 2015
31
Heterozygous p53 knockout mouse model for dehydropyrrolizidine alkaloid-induced carcinogenesis. 38
25690669 2015
32
Peliosis hepatis: Personal experience and literature review. 38
26675327 2015
33
Focal type of peliosis hepatis. 38
26770930 2015
34
Spontaneous hepatic haemorrhage: a review of pathogenesis, aetiology and treatment. 38
26252245 2015
35
Peliosis hepatis disseminated rapidly throughout the liver in a patient with prostate cancer: a case report. 38
26362063 2015
36
Giant hepatocellular adenoma with peliosis hepatis in a child: A diagnostic dilemma. 38
27522744 2015
37
Spontaneous hepatic rupture during pregnancy in a patient with peliosis hepatis. 38
26019044 2015
38
Fatal Hepatic Hemorrhage from Peliosis Hepatis with X-linked Myotubular Myopathy. 38
24172586 2015
39
Endostatin improves cancer-associated systemic syndrome in a lung cancer model. 38
26137006 2015
40
Spontaneous rupture of multifocal hepatocellular carcinoma: case report. 38
26316825 2015
41
Generalised peliosis hepatis mimicking metastases after long-term use of oral contraceptives. 38
26219941 2015
42
A case of intra-abdominal hemorrhage secondary to peliosis hepatis. 38
25576958 2015
43
The N-nitrosodiethylamine mouse model: sketching a timeline of evolution of chemically-induced hepatic lesions. 38
25503129 2014
44
Peliosis Hepatis Shows Isometabolism on (18)F-FDG PET/CT: Two Case Reports. 38
26396637 2014
45
[Focal hepatic peliosis without evident aetiology]. 38
25497607 2014
46
Education and Imaging: hepatobiliary and pancreatic: spontaneous intrahepatic hemorrhage from peliosis hepatis-an uncommon complication of a rare liver disorder. 38
25318383 2014
47
Multifocal peliosis hepatis simulating metastatic malignancy. 38
24890622 2014
48
Ruptured liver caused by peliosis hepatis. 38
24314607 2014
49
Pathogenicity and treatment of Bartonella infections. 38
24933445 2014
50
[Seroprevalence of Bartonella henselae and Bartonella quintana in blood donors in Aydin province, Turkey]. 38
25052114 2014

Variations for Peliosis Hepatis

Expression for Peliosis Hepatis

Search GEO for disease gene expression data for Peliosis Hepatis.

Pathways for Peliosis Hepatis

GO Terms for Peliosis Hepatis

Cellular components related to Peliosis Hepatis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.91 VEGFA SERPINA7 GHRH FN1 F2 COL18A1
2 extracellular exosome GO:0070062 9.81 VIM SORD SERPINA7 ITGA4 GPT FN1
3 extracellular space GO:0005615 9.65 VEGFA SORD SERPINA7 GPT GHRH FN1
4 extracellular matrix GO:0031012 9.62 VEGFA FN1 COL18A1 COL14A1
5 endoplasmic reticulum lumen GO:0005788 9.17 MEN1 FN1 F2 COL18A1 COL14A1 CD4

Biological processes related to Peliosis Hepatis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.72 VEGFA GHRH FN1 F2 COL18A1
2 cytokine-mediated signaling pathway GO:0019221 9.67 VIM VEGFA FN1 CD4
3 cellular protein metabolic process GO:0044267 9.46 MEN1 FN1 F2 AFP
4 positive regulation of endothelial cell apoptotic process GO:2000353 9.43 ITGA4 COL18A1
5 leukocyte tethering or rolling GO:0050901 9.4 SELL ITGA4
6 positive regulation of leukocyte migration GO:0002687 9.26 VEGFA ITGA4
7 extracellular matrix organization GO:0030198 9.26 ITGA4 FN1 COL18A1 COL14A1
8 cell adhesion GO:0007155 9.1 SELL ITGA4 FN1 COL18A1 COL14A1 CD4

Molecular functions related to Peliosis Hepatis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.63 VIM VEGFA SORD FN1 CD4 APEH
2 heparin binding GO:0008201 9.26 VEGFA SELL FN1 F2
3 extracellular matrix structural constituent GO:0005201 8.92 FN1 COL18A1 COL14A1 CD4

Sources for Peliosis Hepatis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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