MCID: PLV003
MIFTS: 56

Pelvic Inflammatory Disease

Categories: Nephrological diseases, Reproductive diseases

Aliases & Classifications for Pelvic Inflammatory Disease

MalaCards integrated aliases for Pelvic Inflammatory Disease:

Name: Pelvic Inflammatory Disease 12 77 56 44 3 45 15 17 74
Pid 12 3

Classifications:



External Ids:

Disease Ontology 12 DOID:1003
MeSH 45 D000292
NCIt 51 C3889
SNOMED-CT 69 37518008
ICD10 34 N70-N77 N73.9
UMLS 74 C0242172

Summaries for Pelvic Inflammatory Disease

MedlinePlus : 44 Pelvic inflammatory disease (PID) is an infection and inflammation of the uterus, ovaries, and other female reproductive organs. It causes scarring in these organs. This can lead to infertility, ectopic pregnancy, pelvic pain, abscesses, and other serious problems. PID is the most common preventable cause of infertility in the United States. Gonorrhea and chlamydia, two sexually transmitted diseases, are the most common causes of PID. Other bacteria can also cause it. You are at greater risk if you Are sexually active and younger than 25 Have more than one sex partner Douche Some women have no symptoms. Others have pain in the lower abdomen, fever, smelly vaginal discharge, irregular bleeding, and pain during intercourse or urination. Doctors diagnose PID with a physical exam, lab tests, and imaging tests. Antibiotics can cure PID. Early treatment is important. Waiting too long increases the risk of infertility. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Pelvic Inflammatory Disease, also known as pid, is related to salpingitis and peritonitis, and has symptoms including fever, pruritus and pelvic pain. An important gene associated with Pelvic Inflammatory Disease is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Copper and Iodine have been mentioned in the context of this disorder. Affiliated tissues include ovary, uterus and testes, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A female reproductive system disease that is characterized by an infection of the female reproductive organs.

CDC : 3 Basic Fact Sheet | Detailed Version

Wikipedia : 77 Pelvic inflammatory disease, also known as pelvic inflammatory disorder (PID), is an infection of the... more...

Related Diseases for Pelvic Inflammatory Disease

Diseases related to Pelvic Inflammatory Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 175)
# Related Disease Score Top Affiliating Genes
1 salpingitis 32.4 CRP HSPD1
2 peritonitis 32.3 CCL2 CRP TLR2
3 chlamydia 31.8 CRP HSPD1 IFNG TLR2 TLR4
4 chlamydia pneumonia 30.2 CRP TLR1
5 urethritis 30.2 HSPD1 TLR1 TLR6
6 toxic shock syndrome 30.1 IFNG TLR2 TLR4
7 cystitis 30.0 CCL2 CRP TLR4
8 fitz-hugh-curtis syndrome 11.6
9 endometritis 11.4
10 heart valve disease 11.1
11 pick disease of brain 11.1
12 benign multicystic peritoneal mesothelioma 11.1
13 infertility 10.5
14 ectopic pregnancy 10.3
15 endometriosis 10.3
16 prosthetic joint infection 10.3 TLR2 TLR4
17 chronic meningitis 10.3 CRP MMP9
18 trench fever 10.3 TLR2 TLR4
19 ovarian cancer 10.3
20 acute cervicitis 10.3 TLR2 TLR4
21 neurosyphilis 10.3 TLR1 TLR2 TLR6
22 dental abscess 10.3 CRP TLR4
23 bacterial meningitis 10.3 CRP MMP9 TLR2
24 fungal keratitis 10.2 MMP9 TLR2 TLR4
25 diabetic foot ulcers 10.2 CCL2 MMP9
26 suppurative otitis media 10.2 CRP TLR2 TLR4
27 septic arthritis 10.2 CRP TLR2 TLR4
28 acute female pelvic peritonitis 10.2
29 scrub typhus 10.2 CRP TLR2 TLR4
30 keratitis, hereditary 10.2 MMP9 TLR2 TLR4
31 bacterial vaginosis 10.2
32 appendicitis 10.2
33 japanese spotted fever 10.2 CCL2 CRP
34 mycobacterium abscessus 10.2 TLR1 TLR2
35 variola major 10.2 IFNG TLR4
36 cervicitis 10.2
37 endocervicitis 10.2 CCL2 TLR4
38 scleritis 10.2 IFNG MMP9
39 tuberculous meningitis 10.2 CCL2 MMP9 TLR2
40 congenital cytomegalovirus 10.2 CCL2 TLR2
41 cerebrovascular disease 10.1 CRP MMP9 TLR4
42 anterior uveitis 10.1 CCL2 TLR4
43 carotid artery disease 10.1 CCL2 CRP MMP9
44 mesenteric lymphadenitis 10.1 CRP HSPD1 TLR2
45 mycoplasma pneumoniae pneumonia 10.1 CRP IFNG TLR2
46 arteries, anomalies of 10.1 CCL2 CRP MMP9
47 aspergillosis 10.1 IFNG TLR2 TLR4
48 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 10.1
49 dementia 10.1
50 campylobacteriosis 10.1 IFNG TLR4

Comorbidity relations with Pelvic Inflammatory Disease via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Pelvic Inflammatory Disease:



Diseases related to Pelvic Inflammatory Disease

Symptoms & Phenotypes for Pelvic Inflammatory Disease

UMLS symptoms related to Pelvic Inflammatory Disease:


fever, pruritus, pelvic pain

MGI Mouse Phenotypes related to Pelvic Inflammatory Disease:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.81 CHI3L1 IFNG MMP9 PLAUR TIRAP TLR1
2 immune system MP:0005387 9.7 CCL2 CHI3L1 CRP IFNG MMP9 PLAUR
3 muscle MP:0005369 9.1 HSPD1 IFNG MMP9 PLAUR TLR2 TLR4

Drugs & Therapeutics for Pelvic Inflammatory Disease

Drugs for Pelvic Inflammatory Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 118)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Copper Approved, Investigational Phase 4,Not Applicable 7440-50-8 27099
2
Iodine Approved, Investigational Phase 4,Not Applicable 7553-56-2 807
3
Povidone Approved Phase 4,Not Applicable 9003-39-8
4
Povidone-iodine Approved Phase 4,Not Applicable 25655-41-8
5
Clindamycin Approved, Vet_approved Phase 4,Not Applicable 18323-44-9 29029
6
Levofloxacin Approved, Investigational Phase 4,Phase 3,Not Applicable 100986-85-4 149096
7
Metronidazole Approved Phase 4,Phase 3,Phase 2,Not Applicable 443-48-1 4173
8
Ofloxacin Approved Phase 4,Phase 3,Not Applicable 82419-36-1 4583
9
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
10
Polyestradiol phosphate Approved Phase 4,Phase 3 28014-46-2
11
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
12
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
13
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
14
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 564-25-0 54671203
15
Amoxicillin Approved, Vet_approved Phase 4,Not Applicable 26787-78-0 33613
16
Azithromycin Approved Phase 4,Phase 3,Not Applicable 83905-01-5 447043 55185
17
Cefazolin Approved Phase 4,Not Applicable 25953-19-9 33255 656510
18
Ertapenem Approved, Investigational Phase 4,Phase 2,Phase 1 153832-46-3 150610
19 Trace Elements Phase 4,Not Applicable
20 Contraceptive Agents Phase 4,Phase 3,Not Applicable
21 Micronutrients Phase 4,Not Applicable
22 Nutrients Phase 4,Not Applicable
23 Anti-Infective Agents, Local Phase 4,Not Applicable
24 Plasma Substitutes Phase 4
25 Blood Substitutes Phase 4
26 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
27 cadexomer iodine Phase 4,Not Applicable
28 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
29 Contraceptives, Oral Phase 4,Phase 3,Not Applicable
30 Antitubercular Agents Phase 4,Phase 2,Phase 3,Not Applicable
31 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
32 Clindamycin phosphate Phase 4,Not Applicable
33 Clindamycin palmitate Phase 4,Not Applicable
34 Gentamicins Phase 4,Phase 2,Phase 3,Not Applicable
35 Anti-Infective Agents, Urinary Phase 4,Phase 3,Not Applicable
36 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Not Applicable
37 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Phase 3,Not Applicable
38 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Not Applicable
39 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Not Applicable
40 Renal Agents Phase 4,Phase 3,Not Applicable
41 Topoisomerase Inhibitors Phase 4,Phase 3,Not Applicable
42 Estradiol 17 beta-cypionate Phase 4,Phase 3
43 Contraceptives, Oral, Combined Phase 4,Phase 3
44 Norgestimate, ethinyl estradiol drug combination Phase 4,Phase 3
45 Estradiol 3-benzoate Phase 4,Phase 3
46 Antimalarials Phase 4,Phase 2,Not Applicable
47 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Not Applicable
48 Lactams Phase 4
49 beta-Lactams Phase 4
50
Ceftriaxone Approved Phase 3,Phase 2 73384-59-5 5479530 5361919

Interventional clinical trials:

(show top 50) (show all 108)
# Name Status NCT ID Phase Drugs
1 Comparison Between Intrauterine Contraceptive Device Insertion During Cesarean Section Vs Conventional Application Unknown status NCT02674139 Phase 4
2 Preoperative Vaginal Cleansing With Povidone Iodine and the Risk of Post Cesarean Endometritis Unknown status NCT02693483 Phase 4 10% povidone iodine
3 To Compare Ofloxacin With Azitromycin for Pelvic Inflammatory Disease (PID) Treatment Completed NCT01241110 Phase 4 Ofloxacin group A, Azitromycin group B;azitromycin
4 Moxifloxacin Versus Ofloxacin Plus Metronidazole in Uncomplicated Pelvic Inflammatory Disease: Multicenter Randomized Controlled Trials Completed NCT01799356 Phase 4 Moxifloxacin;Ofloxacin;Metronidazole
5 Doxycycline Prophylaxis at Vacuum Aspiration Trial Completed NCT00547170 Phase 4 Doxycycline pre-operatively;Doxycycline post-operatively
6 Stage Matched Intervention to Increase Dual Method Use Completed NCT00436306 Phase 4
7 Does Preoperative Vaginal Preparation With Povidone-iodine Before Cesarean Delivery Reduce the Risk of Endometritis? Completed NCT01437228 Phase 4 povidone- iodine solution.;placebo
8 A Trial to Assess the Efficacy and Safety of Morinidazole in Women With Pelvic Inflammatory Disease Recruiting NCT03391440 Phase 4 morinidazole
9 Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries Recruiting NCT03248297 Phase 4 Azithromycin;Azithromycin and amoxicillin;Placebo
10 Antibiotics During Intrauterine Balloon Tamponade Placement Recruiting NCT03478163 Phase 4 CeFAZolin 1000 MG;Clindamycin 900 MG in 6 ML Injection
11 Ertapenem in Patients With Urosepsis Active, not recruiting NCT03859362 Phase 4 Ertapenem Injection
12 Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection Not yet recruiting NCT03532464 Phase 4 azithromycin;doxycycline
13 Treatment Utility of Postpartum Antibiotics in Chorioamnionitis Terminated NCT01585129 Phase 4 Postpartum Antibiotics;No postpartum antibiotics
14 Comparison Study of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis Withdrawn NCT01721616 Phase 4 Azithromycin;Cefazolin
15 A Trial Comparing Moxifloxacin Versus Levofloxacin Plus Metronidazole In Uncomplicated Pelvic Inflammatory Disease Completed NCT00453349 Phase 3 Moxifloxacin (Avelox, BAY12-8039);Levofloxacin & Metronidazole
16 Uncomplicated Pelvic Inflammatory Disease. Treatment With Moxifloxacin. Completed NCT00683865 Phase 3 Ofloxacin;Avelox (Moxifloxacin, BAY12-8039)
17 Study Of Azithromycin Intravenous Formulation Against Pelvic Inflammatory Disease (PID) In Japan Completed NCT00871494 Phase 3 Azithromycin
18 A Phase 3 Study Of Intravenous Metronidazole For Intrabdominal Infection Completed NCT01473836 Phase 3 Metronidazole;Ceftriaxone sodium
19 Home Screening for Chlamydia Surveillance Completed NCT00177437 Phase 3
20 Vasopressin Versus Epinephrine in Myomectomy Completed NCT01861015 Phase 3 Epinephrine;Vasopressin
21 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Completed NCT01633294 Phase 2, Phase 3 Ampicillin + gentamicin
22 Empiric Therapy of Mucopurulent Cervicitis (MPC) Terminated NCT01072136 Phase 3 Azithromycin;Cefixime
23 Clinical Research of TCM on Pelvic Inflammatory Disease Sequelae Unknown status NCT02972151 Phase 2 Comprehensive treatment of TCM
24 The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section Unknown status NCT02742948 Phase 2 ceftriaxone
25 The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID) Completed NCT01160640 Phase 2 Ceftriaxone;Doxycycline;Metronidazole;Placebo Oral Capsule
26 An Investigational Agent for the Treatment of Complicated Intra-Abdominal Infections or Acute Pelvic Infections (0826-038) Completed NCT00092170 Phase 2 MK0826, ertapenem sodium;Comparator: Ticarcillin/Clavulanate
27 The Clinical Effect of Fuke Qianjin Capsule on Chronic Pelvic Pain Caused by Pelvic Inflammation Recruiting NCT03251560 Phase 2 Fuke Qianjin capsule;Placebo oral capsule
28 The Efficacy and Safety of the Xue-Fu-Zhu-Yu Capsule in Treatment of Qi Stagnation and Blood Stasis Syndrome. Recruiting NCT03091634 Phase 2 xue-fu-zhu-yu capsule;xue-fu-zhu-yu capsule simulated agent
29 Two-drug Antibiotic Prophylaxis in Scheduled Cesarean Deliveries Not yet recruiting NCT03960970 Phase 2 Azithromycin 500 mg;Mefoxin 2g
30 Ultrasound-guided Hydrosalpinx Aspiration During Egg Collection Terminated NCT00566956 Phase 2
31 First in Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and to Explore Pharmacodynamics of BAY1834845 Completed NCT03054402 Phase 1 BAY1834845;Placebo
32 Pharmacokinetics and Safety of Ertapenem in the Postpartum Period Terminated NCT01587495 Phase 1 Ertapenem
33 Curcumin Supplementation for Gynecological Diseases Unknown status NCT03016039 Not Applicable
34 Feasibility of Four-dimensional Hysterosalpingo-contrast Sonography With SonoVue for Assessment of Tubal Patency Unknown status NCT02505555
35 ClinicaI Observation of Induced Abortion With Disposable Tissue Suction Tube Unknown status NCT02847910 Not Applicable
36 A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing Unknown status NCT01880918
37 Preovulatory Uterine Flushing With Saline as a Treatment for Unexplained Infertility Unknown status NCT02539290 Not Applicable
38 Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth: a Randomized Controlled Trial Unknown status NCT01945450 Not Applicable Antibiotic prophylaxis;Ampicillin;Gentamycin;Clindamycin
39 A Multicenter Analysis of Levonorgestrel-Intrauterine System (LNG-IUS) Use in the Postpartum Period Unknown status NCT01161095 Not Applicable
40 Rate of Pelvic Inflammatory Disease at St. Michael's Hospital Completed NCT00783419
41 Community-Based Trial of Screening for Chlamydia Trachomatis to Prevent Pelvic Inflammatory Disease Completed NCT00115388 Not Applicable
42 Drug Use Investigation Of Azithromycin IV For Pneumonia Or Pelvic Inflammatory Disease (Regulatory Post Marketing Commitment Plan) Completed NCT01671280 Azithromycin IV
43 Improving Primary Care Follow-up for Patients With Pelvic Inflammatory Disease Completed NCT01299259 Not Applicable
44 Technology Enhanced Community Health Nursing (TECH-N) Study Completed NCT01640379 Not Applicable
45 The Role of Novel Organisms in Acute Endometritis Completed NCT01236131
46 To Compare the Strategies of Universal Antibiotic Prophylaxis Versus Screen-and-treat in Reducing Infective Complications and Re-infection in Women Who Undergo Termination of Pregnancy Completed NCT01842100 Not Applicable Universal antibiotic prophylaxis
47 Immunopathogenesis of Chlamydia Completed NCT00607659
48 Complement Diagnosis of Acute Appendicitis Completed NCT03450642
49 Risk of Acute Liver Injury in Users of Antimicrobials Completed NCT01434173 Moxifloxacin (Avelox, BAY12-8039);Amoxicillin, Amoxicillin plus clavulanic acid, Cefuroxime, Clarithromycin, Doxycycline, Levofloxacin, Telithromycin
50 Recurrent Bacterial Vaginosis and Vaginal Acidifying Gel Trial Completed NCT00545181 Not Applicable Vaginal acidifying gel (RepHresh);Metronidazole control

Search NIH Clinical Center for Pelvic Inflammatory Disease

Cochrane evidence based reviews: pelvic inflammatory disease

Genetic Tests for Pelvic Inflammatory Disease

Anatomical Context for Pelvic Inflammatory Disease

MalaCards organs/tissues related to Pelvic Inflammatory Disease:

42
Ovary, Uterus, Testes, Placenta, Pancreas, Brain, Bone

Publications for Pelvic Inflammatory Disease

Articles related to Pelvic Inflammatory Disease:

(show top 50) (show all 1668)
# Title Authors Year
1
Susceptibility of Endometrial Isolates Recovered from Women with Clinical Pelvic Inflammatory Disease or Histological Endometritis to Antimicrobial Agents. ( 30753898 )
2019
2
Is There a Benefit to Culturing Intra-Uterine Devices in Pelvic Inflammatory Disease? ( 30045030 )
2019
3
Laparoscopic Compared With Open Surgery for Severe Pelvic Inflammatory Disease and Tubo-Ovarian Abscess. ( 31083118 )
2019
4
The Dangers of Hymenotomy for Imperforate Hymen: A Case of Iatrogenic Pelvic Inflammatory Disease with Pyosalpinx. ( 30974214 )
2019
5
Please Be Careful with Me: Discrepancies between Adolescent Expectations and Clinician Perspectives on the Management of Pelvic Inflammatory Disease. ( 30974212 )
2019
6
Trends in diagnosis of pelvic inflammatory disease in an Australian sexual health clinic, 2002-16: before and after clinical audit feedback. ( 30940330 )
2019
7
Benefits of second-look laparoscopy in the management of pelvic inflammatory disease. ( 30910760 )
2019
8
The Risk of Gynecologic and Urinary Tract Cancer with Pelvic Inflammatory Disease: A Population-Based Cohort Study. ( 30662522 )
2019
9
Clinical Features and Therapeutic Response in Women Meeting Criteria for Presumptive Treatment for Pelvic Inflammatory Disease Associated With Mycoplasma genitalium. ( 30640861 )
2019
10
Antibiotic therapy for pelvic inflammatory disease: an abridged version of a Cochrane systematic review and meta-analysis of randomised controlled trials. ( 30341232 )
2019
11
Why a Pelvic Exam is Needed to Diagnose Cervicitis and Pelvic Inflammatory Disease. ( 30902176 )
2019
12
Concurrency of splenomegaly and numerous enlarged mesenteric and retroperitoneal lymph nodes in a patient with pelvic inflammatory disease caused by Edwardsiella tarda: Mimicking lymphoma. ( 30887633 )
2019
13
Protective effects of Asiatic acid against pelvic inflammatory disease in rats. ( 31086602 )
2019
14
Pelvic inflammatory disease: An unusual cause of acute intestinal obstruction. ( 30982548 )
2019
15
Relation between Chlamydia trachomatis infection and pelvic inflammatory disease, ectopic pregnancy and tubal factor infertility in a Dutch cohort of women previously tested for chlamydia in a chlamydia screening trial. ( 30606817 )
2019
16
Chlamydia trachomatis in women with pelvic inflammatory disease (PID): report from a tertiary center in eastern Nepal. ( 30755106 )
2019
17
Fractional-order PID design: Towards transition from state-of-art to state-of-use. ( 30342816 )
2019
18
Evaluation of DSM-5 and ICD-11 personality traits using the Personality Inventory for DSM-5 (PID-5) in a Brazilian sample of psychiatric inpatients. ( 30353698 )
2019
19
Rapid estimation of PID minimum variance. ( 30448252 )
2019
20
The generalized forced oscillation method for tuning PID controllers. ( 30527669 )
2019
21
Analytical fractional PID controller design based on Bode's ideal transfer function plus time delay. ( 30738584 )
2019
22
Optimizing robust PID control of propofol anesthesia for children; design and clinical evaluation. ( 30763237 )
2019
23
Extremum Seeking-based Adaptive PID Control applied to Neuromuscular Electrical Stimulation. ( 30785470 )
2019
24
Optimization Tools Based on Metaheuristics for Performance Enhancement in a Gaussian Adaptive PID Controller. ( 30794197 )
2019
25
The EuroFlow PID Orientation Tube for Flow Cytometric Diagnostic Screening of Primary Immunodeficiencies of the Lymphoid System. ( 30886612 )
2019
26
A Novel dPdI feedback based control scheme using GWO tuned PID controller for efficient MPPT of PEM fuel cell. ( 30898316 )
2019
27
Temperature control of fermentation bioreactor for ethanol production using IMC-PID controller. ( 30911471 )
2019
28
First report of a persistent oropharyngeal infection of type 2 vaccine-derived poliovirus (iVDPV2) in a primary immune deficient (PID) patient after eradication of wild type 2 poliovirus. ( 30953828 )
2019
29
PID Control for Synchronization of Complex Dynamical Networks With Directed Topologies. ( 30990203 )
2019
30
Measurement of pathological personality traits according to the DSM-5: A Polish adaptation of the PID-5. Part I - theoretical foundations. ( 31008462 )
2019
31
Measurement of pathological personality traits according to the DSM-5: A Polish adaptation of the PID-5. Part II - empirical results. ( 31008463 )
2019
32
A novel fractional order PID navigation guidance law by finite time stability approach. ( 31078295 )
2019
33
Oscillations-free PID control of anesthetic drug delivery in neuromuscular blockade. ( 27481776 )
2019
34
A challenging case of pelvic inflammatory disease due to miliary tuberculosis. ( 30117595 )
2018
35
Acupuncture for chronic pelvic inflammatory disease: A systematic review protocol. ( 29595670 )
2018
36
Acute pelvic inflammatory disease as a rare cause of acute small bowel obstruction. ( 29560794 )
2018
37
Discovery of Blood Transcriptional Endotypes in Women with Pelvic Inflammatory Disease. ( 29531169 )
2018
38
Gonococcal and Chlamydial Cases of Pelvic Inflammatory Disease at 2 Canadian Sexually Transmitted Infection Clinics, 2004 to 2014: A Retrospective Cross-sectional Review. ( 29465704 )
2018
39
Pelvic Inflammatory Disease: Possible Catches and Correct Management in Young Women. ( 30112235 )
2018
40
HIV and Syphilis Screening Among Adolescents Diagnosed With Pelvic Inflammatory Disease. ( 30042114 )
2018
41
Safety and efficacy of tigecycline in complicated and uncomplicated pelvic inflammatory disease. ( 29917214 )
2018
42
Patient Satisfaction and Treatment Adherence for Urban Adolescents and Young Adults with Pelvic Inflammatory Disease. ( 29756068 )
2018
43
LC-Q-TOF-MS based plasma metabolomic profile of subclinical pelvic inflammatory disease: A pilot study. ( 29709453 )
2018
44
Anti-Inflammatory Effect of Feiyangchangweiyan Capsule on Rat Pelvic Inflammatory Disease through JNK/NF-κB Pathway. ( 29681986 )
2018
45
Microbiota changes impact on sexually transmitted infections and the development of pelvic inflammatory disease. ( 29452257 )
2018
46
Risk of pelvic inflammatory disease after intrauterine insemination: a systematic review. ( 29287941 )
2018
47
Toll-like receptor variants and cervical Atopobium vaginae infection in women with pelvic inflammatory disease. ( 29286178 )
2018
48
The effect of antibiotic prophylaxis for acute pelvic inflammatory disease after hysterosalpingography: a retrospective cohort study. ( 29239678 )
2018
49
2017 European guideline for the management of pelvic inflammatory disease. ( 29198181 )
2018
50
Predictive factors for emergent surgical intervention in patients with ovarian endometrioma hospitalized for pelvic inflammatory disease: A retrospective observational study. ( 29171117 )
2018

Variations for Pelvic Inflammatory Disease

Expression for Pelvic Inflammatory Disease

Search GEO for disease gene expression data for Pelvic Inflammatory Disease.

Pathways for Pelvic Inflammatory Disease

Pathways related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show all 32)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.86 CCL2 CHI3L1 CRP IFNG MMP9 PLAUR
2
Show member pathways
13.27 CCL2 TIRAP TLR1 TLR2 TLR4 TLR6
3
Show member pathways
12.94 CCL2 IFNG TIRAP TLR1 TLR2 TLR4
4
Show member pathways
12.83 CCL2 MMP9 TIRAP TLR2 TLR4
5
Show member pathways
12.57 TLR1 TLR2 TLR4 TLR6
6
Show member pathways
12.53 TIRAP TLR1 TLR2 TLR4 TLR6
7 12.5 CCL2 IFNG TLR1 TLR2 TLR6
8
Show member pathways
12.38 TIRAP TLR1 TLR2 TLR4 TLR6
9
Show member pathways
12.33 TIRAP TLR1 TLR2 TLR4 TLR6
10
Show member pathways
12.26 CCL2 IFNG MMP9 TLR2
11 12.22 MMP9 PLAUR TLR2 TLR4
12
Show member pathways
12.15 TIRAP TLR1 TLR2 TLR4 TLR6
13
Show member pathways
12.13 CCL2 MMP9 TLR1 TLR2 TLR4 TLR6
14
Show member pathways
12.02 IFNG TIRAP TLR1 TLR2 TLR4 TLR6
15 12.01 TLR2 TLR4 TLR6
16 11.97 CCL2 IFNG MMP9
17
Show member pathways
11.97 TLR1 TLR2 TLR4 TLR6
18 11.95 CCL2 IFNG MMP9 TLR4
19 11.95 IFNG MMP9 TLR1 TLR2 TLR4 TLR6
20 11.95 HSPD1 IFNG TIRAP TLR1 TLR2 TLR4
21
Show member pathways
11.88 IFNG TLR1 TLR2 TLR4 TLR6
22 11.79 IFNG TLR2 TLR4
23 11.77 CCL2 IFNG TLR2 TLR4
24 11.73 TLR1 TLR2 TLR4 TLR6
25 11.66 CCL2 IFNG MMP9
26 11.53 HSPD1 TLR2 TLR4
27 11.42 CCL2 IFNG TLR2 TLR4
28 11.39 CCL2 IFNG TLR2 TLR4
29 11.31 CCL2 MMP9 PLAUR
30 11.27 CCL2 MMP9 TLR4
31
Show member pathways
11.27 HSPD1 IFNG MMP9 TLR1 TLR2 TLR4
32 10.75 CCL2 IFNG MMP9 TLR1 TLR2

GO Terms for Pelvic Inflammatory Disease

Cellular components related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.87 CCL2 CHI3L1 CLEC3B CRP HSPD1 IFNG
2 phagocytic vesicle membrane GO:0030670 9.43 TLR1 TLR2 TLR6
3 membrane raft GO:0045121 9.33 TLR1 TLR2 TLR6
4 lipopolysaccharide receptor complex GO:0046696 8.96 HSPD1 TLR4
5 Toll-like receptor 1-Toll-like receptor 2 protein complex GO:0035354 8.62 TLR1 TLR2

Biological processes related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 58)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.99 CCL2 IFNG TLR1 TLR2 TLR4 TLR6
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.97 CCL2 CHI3L1 TIRAP TLR4
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.9 TIRAP TLR2 TLR4 TLR6
4 cellular response to interferon-gamma GO:0071346 9.87 CCL2 TLR2 TLR4
5 defense response to Gram-positive bacterium GO:0050830 9.87 CRP TIRAP TLR2
6 positive regulation of interleukin-6 production GO:0032755 9.83 HSPD1 TLR2 TLR4
7 positive regulation of tumor necrosis factor production GO:0032760 9.83 TIRAP TLR2 TLR4
8 response to lipopolysaccharide GO:0032496 9.81 TIRAP TLR2 TLR4
9 positive regulation of nitric oxide biosynthetic process GO:0045429 9.81 IFNG TLR4 TLR6
10 lipopolysaccharide-mediated signaling pathway GO:0031663 9.77 CCL2 TLR2 TLR4
11 inflammatory response GO:0006954 9.76 CCL2 CHI3L1 CRP TIRAP TLR1 TLR2
12 positive regulation of interferon-beta production GO:0032728 9.72 TLR2 TLR4
13 negative regulation of intrinsic apoptotic signaling pathway GO:2001243 9.72 MMP9 PLAUR
14 positive regulation of T cell activation GO:0050870 9.72 CCL2 HSPD1
15 TRIF-dependent toll-like receptor signaling pathway GO:0035666 9.72 TLR4 TLR6
16 positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9.72 MMP9 PLAUR
17 positive regulation of interleukin-8 production GO:0032757 9.72 TIRAP TLR2 TLR4
18 positive regulation of chemokine production GO:0032722 9.71 TLR2 TLR4
19 microglial cell activation GO:0001774 9.71 TLR2 TLR6
20 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.71 TLR4 TLR6
21 positive regulation of interleukin-8 secretion GO:2000484 9.71 TLR1 TLR2
22 positive regulation of reactive oxygen species biosynthetic process GO:1903428 9.71 TLR4 TLR6
23 positive regulation of interleukin-10 production GO:0032733 9.71 HSPD1 TLR2 TLR4
24 positive regulation of interferon-alpha production GO:0032727 9.7 HSPD1 TLR4
25 I-kappaB phosphorylation GO:0007252 9.7 TLR2 TLR4
26 negative regulation of interleukin-17 production GO:0032700 9.69 IFNG TLR4
27 macrophage activation GO:0042116 9.69 TLR1 TLR4
28 positive regulation of tumor necrosis factor biosynthetic process GO:0042535 9.68 TLR1 TLR4
29 positive regulation of inflammatory response GO:0050729 9.68 TLR2 TLR4
30 cellular response to oxidised low-density lipoprotein particle stimulus GO:0140052 9.68 TLR4 TLR6
31 interleukin-1 beta secretion GO:0050702 9.68 TLR4 TLR6
32 positive regulation of NLRP3 inflammasome complex assembly GO:1900227 9.67 TLR4 TLR6
33 positive regulation of toll-like receptor 2 signaling pathway GO:0034137 9.67 TIRAP TLR1
34 activation of NF-kappaB-inducing kinase activity GO:0007250 9.67 CHI3L1 TIRAP TLR6
35 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:2001268 9.66 MMP9 PLAUR
36 cellular response to diacyl bacterial lipopeptide GO:0071726 9.65 TLR2 TLR6
37 positive regulation of macrophage activation GO:0043032 9.65 HSPD1 TLR4 TLR6
38 toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 9.64 TLR2 TLR6
39 cellular response to bacterial lipopeptide GO:0071221 9.63 TIRAP TLR2
40 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.63 CCL2 TLR2 TLR4
41 cellular response to triacyl bacterial lipopeptide GO:0071727 9.62 TLR1 TLR2
42 nitric oxide metabolic process GO:0046209 9.62 TLR2 TLR6
43 toll-like receptor signaling pathway GO:0002224 9.62 TLR1 TLR2 TLR4 TLR6
44 positive regulation of oxidative stress-induced neuron death GO:1903223 9.61 TLR4 TLR6
45 toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 9.61 TLR1 TLR2
46 cell activation GO:0001775 9.61 TLR1 TLR2 TLR6
47 detection of diacyl bacterial lipopeptide GO:0042496 9.58 TLR2 TLR6
48 detection of triacyl bacterial lipopeptide GO:0042495 9.58 TLR1 TLR2
49 cellular response to lipoteichoic acid GO:0071223 9.58 TIRAP TLR2 TLR4
50 positive regulation of cellular response to macrophage colony-stimulating factor stimulus GO:1903974 9.57 TLR2 TLR4

Molecular functions related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.87 CRP MMP9 TIRAP TLR1 TLR2 TLR4
2 signaling receptor binding GO:0005102 9.73 CCL2 PLAUR TLR4 TLR6
3 protein heterodimerization activity GO:0046982 9.65 TIRAP TLR1 TLR2 TLR4 TLR6
4 signaling receptor activity GO:0038023 9.55 PLAUR TLR1 TLR2 TLR4 TLR6
5 lipopolysaccharide binding GO:0001530 9.54 HSPD1 TLR2 TLR4
6 lipopolysaccharide receptor activity GO:0001875 9.4 TLR2 TLR4
7 lipopeptide binding GO:0071723 9.13 TLR1 TLR2 TLR6
8 Toll-like receptor 2 binding GO:0035663 8.8 TIRAP TLR1 TLR6

Sources for Pelvic Inflammatory Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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