PID
MCID: PLV003
MIFTS: 55

Pelvic Inflammatory Disease (PID)

Categories: Nephrological diseases, Reproductive diseases

Aliases & Classifications for Pelvic Inflammatory Disease

MalaCards integrated aliases for Pelvic Inflammatory Disease:

Name: Pelvic Inflammatory Disease 12 76 55 43 3 44 15 73
Pid 12 3

Classifications:



External Ids:

Disease Ontology 12 DOID:1003
ICD10 33 N70-N77 N73.9
MeSH 44 D000292
NCIt 50 C3889
SNOMED-CT 68 37518008
UMLS 73 C0242172

Summaries for Pelvic Inflammatory Disease

MedlinePlus : 43 Pelvic inflammatory disease (PID) is an infection and inflammation of the uterus, ovaries, and other female reproductive organs. It causes scarring in these organs. This can lead to infertility, ectopic pregnancy, pelvic pain, abscesses, and other serious problems. PID is the most common preventable cause of infertility in the United States. Gonorrhea and chlamydia, two sexually transmitted diseases, are the most common causes of PID. Other bacteria can also cause it. You are at greater risk if you Are sexually active and younger than 25 Have more than one sex partner Douche Some women have no symptoms. Others have pain in the lower abdomen, fever, smelly vaginal discharge, irregular bleeding, and pain during intercourse or urination. Doctors diagnose PID with a physical exam, lab tests, and imaging tests. Antibiotics can cure PID. Early treatment is important. Waiting too long increases the risk of infertility. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Pelvic Inflammatory Disease, also known as pid, is related to salpingitis and chlamydia, and has symptoms including fever, pruritus and pelvic pain. An important gene associated with Pelvic Inflammatory Disease is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Copper and Povidone-iodine have been mentioned in the context of this disorder. Affiliated tissues include ovary, uterus and testes, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A female reproductive system disease that is characterized by an infection of the female reproductive organs.

CDC : 3 Basic Fact Sheet | Detailed Version

Wikipedia : 76 Pelvic inflammatory disease, also known as pelvic inflammatory disorder (PID), is an infection of the... more...

Related Diseases for Pelvic Inflammatory Disease

Diseases related to Pelvic Inflammatory Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 151)
# Related Disease Score Top Affiliating Genes
1 salpingitis 32.3 CRP HSPD1
2 chlamydia 32.2 TLR4 TLR2 HSPD1 CRP
3 peritonitis 31.7 TLR2 MPO CRP CCL2
4 urethritis 30.1 TLR6 TLR1 HSPD1
5 appendicitis 30.0 CRP MMP9 MPO
6 cystitis 29.7 CCL2 CRP TLR4
7 myocardial infarction 29.4 CCL2 CRP MMP9 MPO TLR4
8 pneumonia 29.4 TLR4 TLR2 MPO CRP CCL2
9 fitz-hugh-curtis syndrome 11.5
10 endometritis 11.4
11 pick disease of brain 11.0
12 benign multicystic peritoneal mesothelioma 11.0
13 heart valve disease 11.0
14 infertility 10.5
15 ectopic pregnancy 10.3
16 endometriosis 10.3
17 ovarian cancer 10.3
18 chlamydia pneumonia 10.2 CRP TLR1
19 prosthetic joint infection 10.2 TLR2 TLR4
20 trench fever 10.2 TLR2 TLR4
21 chronic meningitis 10.2 CRP MMP9
22 bacterial vaginosis 10.2
23 acute female pelvic peritonitis 10.2
24 neurosyphilis 10.2 TLR6 TLR2 TLR1
25 acute cervicitis 10.2 TLR2 TLR4
26 anterior uveitis 10.2 TLR2 TLR4
27 diabetic foot ulcers 10.2 CCL2 MMP9
28 dental abscess 10.2 CRP TLR4
29 mycobacterium abscessus 10.2 TLR1 TLR2
30 bacterial meningitis 10.2 CRP MMP9 TLR2
31 fungal keratitis 10.2 TLR4 TLR2 MMP9
32 q fever 10.2 TLR1 TLR2 TLR4
33 melioidosis 10.1 TLR1 TLR2 TLR4
34 suppurative otitis media 10.1 CRP TLR2 TLR4
35 septic arthritis 10.1 CRP TLR2 TLR4
36 scrub typhus 10.1 CRP TLR2 TLR4
37 scleritis 10.1 CCL2 MMP9
38 keratitis, hereditary 10.1 MMP9 TLR2 TLR4
39 myositis fibrosa 10.1 TLR2 TLR4
40 cervicitis 10.1
41 viral infectious disease 10.1
42 japanese spotted fever 10.1 CCL2 CRP
43 congenital cytomegalovirus 10.1 CCL2 TLR2
44 endocervicitis 10.1 CCL2 TLR4
45 tuberculous meningitis 10.1 CCL2 MMP9 TLR2
46 gastrointestinal system disease 10.1 CRP MMP9 TLR4
47 cerebrovascular disease 10.1 CRP MMP9 TLR4
48 extrapulmonary tuberculosis 10.1 CCL2 TIRAP TLR2
49 carotid artery disease 10.1 CCL2 CRP MMP9
50 leprosy 3 10.1 HSPD1 TLR1 TLR2

Comorbidity relations with Pelvic Inflammatory Disease via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Pelvic Inflammatory Disease:



Diseases related to Pelvic Inflammatory Disease

Symptoms & Phenotypes for Pelvic Inflammatory Disease

UMLS symptoms related to Pelvic Inflammatory Disease:


fever, pruritus, pelvic pain

MGI Mouse Phenotypes related to Pelvic Inflammatory Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.81 CHI3L1 MMP9 MPO PLAUR TIRAP TLR1
2 immune system MP:0005387 9.7 CCL2 CHI3L1 CRP MMP9 MPO PLAUR
3 muscle MP:0005369 9.1 HSPD1 MMP9 MPO PLAUR TLR2 TLR4

Drugs & Therapeutics for Pelvic Inflammatory Disease

Drugs for Pelvic Inflammatory Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 120)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Copper Approved, Investigational Phase 4,Not Applicable 7440-50-8 27099
2
Povidone-iodine Approved Phase 4,Not Applicable 25655-41-8
3
Povidone Approved Phase 4,Not Applicable 9003-39-8
4
Iodine Approved, Investigational Phase 4,Not Applicable 7553-56-2 807
5
Levofloxacin Approved, Investigational Phase 4,Phase 3,Not Applicable 100986-85-4 149096
6
Ofloxacin Approved Phase 4,Phase 3,Not Applicable 82419-36-1 4583
7
Clindamycin Approved, Vet_approved Phase 4,Not Applicable 18323-44-9 29029
8
Metronidazole Approved Phase 4,Phase 3,Phase 2,Not Applicable 443-48-1 4173
9
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
10
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
11
Polyestradiol phosphate Approved Phase 4,Phase 3 28014-46-2
12
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
13
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
14 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3 979-32-8
15
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 564-25-0 54671203
16
Azithromycin Approved Phase 4,Phase 3,Not Applicable 83905-01-5 55185 447043
17
Amoxicillin Approved, Vet_approved Phase 4,Not Applicable 26787-78-0 33613
18
Cefazolin Approved Phase 4,Not Applicable 25953-19-9 656510 33255
19 Trace Elements Phase 4,Not Applicable
20 Contraceptive Agents Phase 4,Phase 3,Not Applicable
21 Micronutrients Phase 4,Not Applicable
22 Anti-Infective Agents, Local Phase 4,Not Applicable
23 cadexomer iodine Phase 4,Not Applicable
24 Plasma Substitutes Phase 4
25 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
26 Blood Substitutes Phase 4
27 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
28 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Not Applicable
29 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Not Applicable
30 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Not Applicable
31 Renal Agents Phase 4,Phase 3,Not Applicable
32 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Phase 3,Not Applicable
33 Anti-Infective Agents, Urinary Phase 4,Phase 3,Not Applicable
34 Topoisomerase Inhibitors Phase 4,Phase 3,Not Applicable
35 Contraceptives, Oral Phase 4,Phase 3,Not Applicable
36 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
37 Antitubercular Agents Phase 4,Phase 2,Phase 3,Not Applicable
38 Clindamycin palmitate Phase 4,Not Applicable
39 Clindamycin phosphate Phase 4,Not Applicable
40 Gentamicins Phase 4,Phase 2,Phase 3,Not Applicable
41 Fluoroquinolones Phase 4,Phase 3
42 Norgestimate, ethinyl estradiol drug combination Phase 4,Phase 3
43 Estradiol 17 beta-cypionate Phase 4,Phase 3
44 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3
45 Estradiol 3-benzoate Phase 4,Phase 3
46 Contraceptives, Oral, Combined Phase 4,Phase 3
47 Antimalarials Phase 4,Phase 2,Not Applicable
48 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Not Applicable
49 beta-Lactams Phase 4
50 Lactams Phase 4

Interventional clinical trials:

(show top 50) (show all 104)
# Name Status NCT ID Phase Drugs
1 Comparison Between Intrauterine Contraceptive Device Insertion During Cesarean Section Vs Conventional Application Unknown status NCT02674139 Phase 4
2 Preoperative Vaginal Cleansing With Povidone Iodine and the Risk of Post Cesarean Endometritis Unknown status NCT02693483 Phase 4 10% povidone iodine
3 To Compare Ofloxacin With Azitromycin for Pelvic Inflammatory Disease (PID) Treatment Completed NCT01241110 Phase 4 Ofloxacin group A, Azitromycin group B;azitromycin
4 Moxifloxacin Versus Ofloxacin Plus Metronidazole in Uncomplicated Pelvic Inflammatory Disease: Multicenter Randomized Controlled Trials Completed NCT01799356 Phase 4 Moxifloxacin;Ofloxacin;Metronidazole
5 Doxycycline Prophylaxis at Vacuum Aspiration Trial Completed NCT00547170 Phase 4 Doxycycline pre-operatively;Doxycycline post-operatively
6 Stage Matched Intervention to Increase Dual Method Use Completed NCT00436306 Phase 4
7 Does Preoperative Vaginal Preparation With Povidone-iodine Before Cesarean Delivery Reduce the Risk of Endometritis? Completed NCT01437228 Phase 4 povidone- iodine solution.;placebo
8 A Trial to Assess the Efficacy and Safety of Morinidazole in Women With Pelvic Inflammatory Disease Recruiting NCT03391440 Phase 4 morinidazole
9 Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries Recruiting NCT03248297 Phase 4 Azithromycin;Azithromycin and amoxicillin;Placebo
10 Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection Not yet recruiting NCT03532464 Phase 4 azithromycin;doxycycline
11 Antibiotics During Intrauterine Balloon Tamponade Placement Not yet recruiting NCT03478163 Phase 4 CeFAZolin 1000 MG;Clindamycin 900 MG in 6 ML Injection
12 Treatment Utility of Postpartum Antibiotics in Chorioamnionitis Terminated NCT01585129 Phase 4 Postpartum Antibiotics;No postpartum antibiotics
13 Comparison Study of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis Withdrawn NCT01721616 Phase 4 Azithromycin;Cefazolin
14 A Trial Comparing Moxifloxacin Versus Levofloxacin Plus Metronidazole In Uncomplicated Pelvic Inflammatory Disease Completed NCT00453349 Phase 3 Moxifloxacin (Avelox, BAY12-8039);Levofloxacin & Metronidazole
15 Uncomplicated Pelvic Inflammatory Disease. Treatment With Moxifloxacin. Completed NCT00683865 Phase 3 Ofloxacin;Avelox (Moxifloxacin, BAY12-8039)
16 Study Of Azithromycin Intravenous Formulation Against Pelvic Inflammatory Disease (PID) In Japan Completed NCT00871494 Phase 3 Azithromycin
17 A Phase 3 Study Of Intravenous Metronidazole For Intrabdominal Infection Completed NCT01473836 Phase 3 Metronidazole;Ceftriaxone sodium
18 Home Screening for Chlamydia Surveillance Completed NCT00177437 Phase 3
19 Vasopressin Versus Epinephrine in Myomectomy Completed NCT01861015 Phase 3 Epinephrine;Vasopressin
20 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Completed NCT01633294 Phase 2, Phase 3 Ampicillin + gentamicin
21 Empiric Therapy of Mucopurulent Cervicitis (MPC) Terminated NCT01072136 Phase 3 Azithromycin;Cefixime
22 Clinical Research of TCM on Pelvic Inflammatory Disease Sequelae Unknown status NCT02972151 Phase 2 Comprehensive treatment of TCM
23 The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section Unknown status NCT02742948 Phase 2 ceftriaxone
24 The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID) Completed NCT01160640 Phase 2 Ceftriaxone;Doxycycline;Metronidazole;Placebo Oral Capsule
25 An Investigational Agent for the Treatment of Complicated Intra-Abdominal Infections or Acute Pelvic Infections (0826-038) Completed NCT00092170 Phase 2 MK0826, ertapenem sodium;Comparator: Ticarcillin/Clavulanate
26 The Clinical Effect of Fuke Qianjin Capsule on Chronic Pelvic Pain Caused by Pelvic Inflammation Recruiting NCT03251560 Phase 2 Fuke Qianjin capsule;Placebo oral capsule
27 The Efficacy and Safety of the Xue-Fu-Zhu-Yu Capsule in Treatment of Qi Stagnation and Blood Stasis Syndrome. Recruiting NCT03091634 Phase 2 xue-fu-zhu-yu capsule;xue-fu-zhu-yu capsule simulated agent
28 Ultrasound-guided Hydrosalpinx Aspiration During Egg Collection Terminated NCT00566956 Phase 2
29 First in Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and to Explore Pharmacodynamics of BAY1834845 Completed NCT03054402 Phase 1 BAY1834845;Placebo
30 Pharmacokinetics and Safety of Ertapenem in the Postpartum Period Terminated NCT01587495 Phase 1 Ertapenem
31 Curcumin Supplementation for Gynecological Diseases Unknown status NCT03016039 Not Applicable
32 Feasibility of Four-dimensional Hysterosalpingo-contrast Sonography With SonoVue for Assessment of Tubal Patency Unknown status NCT02505555
33 ClinicaI Observation of Induced Abortion With Disposable Tissue Suction Tube Unknown status NCT02847910 Not Applicable
34 A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing Unknown status NCT01880918
35 RCT(Randomized Clinical Trial ) of Antibiotic Therapy in Chronic Endometritis Unknown status NCT02648698 Not Applicable antibiotics;placebo
36 Single or Triple Uterine Tourniquet at Myomectomy Unknown status NCT02392585 Not Applicable
37 Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth: a Randomized Controlled Trial Unknown status NCT01945450 Not Applicable Antibiotic prophylaxis;Ampicillin;Gentamycin;Clindamycin
38 A Multicenter Analysis of Levonorgestrel-Intrauterine System (LNG-IUS) Use in the Postpartum Period Unknown status NCT01161095 Not Applicable
39 Rate of Pelvic Inflammatory Disease at St. Michael's Hospital Completed NCT00783419
40 Community-Based Trial of Screening for Chlamydia Trachomatis to Prevent Pelvic Inflammatory Disease Completed NCT00115388 Not Applicable
41 Drug Use Investigation Of Azithromycin IV For Pneumonia Or Pelvic Inflammatory Disease (Regulatory Post Marketing Commitment Plan) Completed NCT01671280 Azithromycin IV
42 Improving Primary Care Follow-up for Patients With Pelvic Inflammatory Disease Completed NCT01299259 Not Applicable
43 Technology Enhanced Community Health Nursing (TECH-N) Study Completed NCT01640379 Not Applicable
44 The Role of Novel Organisms in Acute Endometritis Completed NCT01236131
45 To Compare the Strategies of Universal Antibiotic Prophylaxis Versus Screen-and-treat in Reducing Infective Complications and Re-infection in Women Who Undergo Termination of Pregnancy Completed NCT01842100 Not Applicable Universal antibiotic prophylaxis
46 Immunopathogenesis of Chlamydia Completed NCT00607659
47 Complement Diagnosis of Acute Appendicitis Completed NCT03450642
48 Risk of Acute Liver Injury in Users of Antimicrobials Completed NCT01434173 Moxifloxacin (Avelox, BAY12-8039);Amoxicillin, Amoxicillin plus clavulanic acid, Cefuroxime, Clarithromycin, Doxycycline, Levofloxacin, Telithromycin
49 Recurrent Bacterial Vaginosis and Vaginal Acidifying Gel Trial Completed NCT00545181 Not Applicable Vaginal acidifying gel (RepHresh);Metronidazole control
50 Home Sampling Versus Conventional Sampling for Screening of Urogenital Chlamydia Trachomatis in Young Men and Women. Completed NCT00283127 Not Applicable

Search NIH Clinical Center for Pelvic Inflammatory Disease

Cochrane evidence based reviews: pelvic inflammatory disease

Genetic Tests for Pelvic Inflammatory Disease

Anatomical Context for Pelvic Inflammatory Disease

MalaCards organs/tissues related to Pelvic Inflammatory Disease:

41
Ovary, Uterus, Testes, Liver, Brain, Lung, Skin

Publications for Pelvic Inflammatory Disease

Articles related to Pelvic Inflammatory Disease:

(show top 50) (show all 1336)
# Title Authors Year
1
Gonococcal and Chlamydial Cases of Pelvic Inflammatory Disease at 2 Canadian Sexually Transmitted Infection Clinics, 2004 to 2014: A Retrospective Cross-sectional Review. ( 29465704 )
2018
2
Toll-like receptor variants and cervical Atopobium vaginae infection in women with pelvic inflammatory disease. ( 29286178 )
2018
3
Sustained Simultaneous Delivery of Metronidazole and Doxycycline From Polycaprolactone Matrices Designed for Intravaginal Treatment of Pelvic Inflammatory Disease. ( 29100864 )
2018
4
Impact of the Levonorgestrel-Releasing Intrauterine System on the Progression of Chlamydia trachomatis Infection to Pelvic Inflammatory Disease in a Baboon Model. ( 29253201 )
2018
5
Patient Satisfaction and Treatment Adherence for Urban Adolescents and Young Adults with Pelvic Inflammatory Disease. ( 29756068 )
2018
6
Trends in pelvic inflammatory disease emergency department visits, United States, 2006-2013. ( 29045851 )
2018
7
Risk of pelvic inflammatory disease after intrauterine insemination: a systematic review. ( 29287941 )
2018
8
LC-Q-TOF-MS based plasma metabolomic profile of subclinical pelvic inflammatory disease: A pilot study. ( 29709453 )
2018
9
Acupuncture for chronic pelvic inflammatory disease: A systematic review protocol. ( 29595670 )
2018
10
Discovery of Blood Transcriptional Endotypes in Women with Pelvic Inflammatory Disease. ( 29531169 )
2018
11
Anti-Inflammatory Effect of Feiyangchangweiyan Capsule on Rat Pelvic Inflammatory Disease through JNK/NF-<i>I_</i>B Pathway. ( 29681986 )
2018
12
Pelvic Inflammatory Disease (PID) ( 29763134 )
2018
13
Repeat Chlamydia Diagnoses Increase the Hazard of Pelvic Inflammatory Disease among U.S. Army females: A Retrospective Cohort Analysis. ( 29870505 )
2018
14
Predictive factors for emergent surgical intervention in patients with ovarian endometrioma hospitalized for pelvic inflammatory disease: A retrospective observational study. ( 29171117 )
2018
15
Rates of pelvic inflammatory disease and ectopic pregnancy in Australia, 2009-2014: ecological analysis of hospital data. ( 29720385 )
2018
16
Acute pelvic inflammatory disease as a rare cause of acute small bowel obstruction. ( 29560794 )
2018
17
Pelvic inflammatory disease risk following negative results from chlamydia nucleic acid amplification tests (NAATs) versus non-NAATs in Denmark: A retrospective cohort. ( 29293503 )
2018
18
The effect of antibiotic prophylaxis for acute pelvic inflammatory disease after hysterosalpingography: a retrospective cohort study. ( 29239678 )
2018
19
Safety and efficacy of tigecycline in complicated and uncomplicated pelvic inflammatory disease. ( 29917214 )
2018
20
Risk of Pelvic Inflammatory Disease in Relation to Chlamydia and Gonorrhea Testing, Repeat Testing, and Positivity: A Population-Based Cohort Study. ( 29136127 )
2018
21
Risk of high-grade serous ovarian cancer associated with pelvic inflammatory disease, parity and breast cancer. ( 29935395 )
2018
22
Microbiota changes impact on sexually transmitted infections and the development of pelvic inflammatory disease. ( 29452257 )
2018
23
2017 European guideline for the management of pelvic inflammatory disease. ( 29198181 )
2018
24
Clinical utility of the DSM-5 alternative model for borderline personality disorder: Differential diagnostic accuracy of the BFI, SCID-II-PQ, and PID-5. ( 29069625 )
2018
25
The Additive Value of Pelvic Examinations to History in Predicting Sexually Transmitted Infections for Young Female Patients With Suspected Cervicitis or Pelvic Inflammatory Disease. ( 30251627 )
2018
26
Comparison of three serological assays to measure antibody response to Chlamydia antigen Pgp3 in adolescent and young adults with pelvic inflammatory disease. ( 30049256 )
2018
27
Dimensional Personality Assessment among a Chronic Fatigue Syndrome (CFS) sample with Personality Inventory for DSM-5 (PID-5). ( 30079926 )
2018
28
Quality of life and paracetamol in advanced dementia (Q-PID): protocol of a randomised double-blind placebo-controlled crossover trial. ( 30428836 )
2018
29
Association of Pelvic Inflammatory Disease with Risk of Endometriosis: A Nationwide Cohort Study Involving 141,460 Individuals. ( 30352985 )
2018
30
Comparison of the prevalence of adhesions at the time of diagnostic laparoscopy for infertility between patient who had open myomectomy and those who had no previous pelvic-abdominal surgery or pelvic inflammatory disease. ( 30417838 )
2018
31
Relationships between female infertility and female genital infections and pelvic inflammatory disease: a population-based nested controlled study. ( 30110069 )
2018
32
A challenging case of pelvic inflammatory disease due to miliary tuberculosis. ( 30117595 )
2018
33
HIV and Syphilis Screening Among Adolescents Diagnosed With Pelvic Inflammatory Disease. ( 30042114 )
2018
34
Is There a Benefit to Culturing Intra-Uterine Devices in Pelvic Inflammatory Disease? ( 30045030 )
2018
35
Pelvic Inflammatory Disease: Possible Catches and Correct Management in Young Women. ( 30112235 )
2018
36
Characterization of pelvic and cervical microbiotas from patients with pelvic inflammatory disease. ( 30113305 )
2018
37
Relationship Status and Sexual Behaviors in Post-Pelvic Inflammatory Disease (PID) Affected Urban Young Women: A Sub-Study of a Randomized Controlled Trial. ( 30221216 )
2018
38
Uncommon cause of pelvic inflammatory disease leading to toxic shock syndrome. ( 30249728 )
2018
39
Trends in Pelvic Inflammatory Disease Among American Indian and Alaska Native Women, Indian Health Service, 2001-2015. ( 30252529 )
2018
40
Ozone therapy ameliorates inflammation and endometrial injury in rats with pelvic inflammatory disease. ( 30257358 )
2018
41
Therapeutic impact of initial treatment for C>hlamydia trachomatis among patients with pelvic inflammatory disease: a retrospective cohort study using a national inpatient database in Japan. ( 30312389 )
2018
42
Antibiotic therapy for pelvic inflammatory disease: an abridged version of a Cochrane systematic review and meta-analysis of randomised controlled trials. ( 30341232 )
2018
43
Pelvic inflammatory disease: management requires a patient, prudent, prejudice-free provider. ( 30422800 )
2018
44
The first reported case of pelvic inflammatory disease caused by Actinobaculum massiliense. ( 30439470 )
2018
45
Metabonomic study of the protective effect of Fukeqianjin formula on multi-pathogen induced pelvic inflammatory disease in rats. ( 30555525 )
2018
46
Effectiveness of the Co-PID for Students With Moderate Intellectual Disability. ( 29426387 )
2018
47
Utility of the Personality Inventory for DSM-5-Brief Form (PID-5-BF) in the Measurement of Maladaptive Personality and Psychopathology. ( 27827808 )
2018
48
Personality Inventory for DSM-5 (PID-5) in Clinical Versus Nonclinical Individuals: Generalizability of Psychometric Features. ( 28503935 )
2018
49
Development and validation of an Overreporting Scale for the Personality Inventory for DSM-5 (PID-5). ( 28557479 )
2018
50
Intelligent tuning method of PID parameters based on iterative learning control for atomic force microscopy. ( 29054026 )
2018

Variations for Pelvic Inflammatory Disease

Expression for Pelvic Inflammatory Disease

Search GEO for disease gene expression data for Pelvic Inflammatory Disease.

Pathways for Pelvic Inflammatory Disease

Pathways related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.77 CCL2 CHI3L1 CRP MMP9 MPO PLAUR
2
Show member pathways
13.27 CCL2 TIRAP TLR1 TLR2 TLR4 TLR6
3
Show member pathways
12.92 CCL2 MMP9 TIRAP TLR2 TLR4
4
Show member pathways
12.9 CCL2 TIRAP TLR1 TLR2 TLR4 TLR6
5
Show member pathways
12.57 TLR1 TLR2 TLR4 TLR6
6
Show member pathways
12.53 TIRAP TLR1 TLR2 TLR4 TLR6
7 12.44 CCL2 MPO TLR1 TLR2 TLR6
8
Show member pathways
12.3 TIRAP TLR1 TLR2 TLR4 TLR6
9
Show member pathways
12.27 TIRAP TLR1 TLR2 TLR4 TLR6
10 12.22 MMP9 PLAUR TLR2 TLR4
11 12.06 MPO TLR2 TLR4 TLR6
12
Show member pathways
12.06 CCL2 MMP9 TLR1 TLR2 TLR4 TLR6
13
Show member pathways
12.04 TIRAP TLR1 TLR2 TLR4 TLR6
14
Show member pathways
11.95 TLR1 TLR2 TLR4 TLR6
15
Show member pathways
11.94 TIRAP TLR1 TLR2 TLR4 TLR6
16
Show member pathways
11.9 TLR1 TLR2 TLR4 TLR6
17 11.89 CCL2 MMP9 TLR4
18 11.87 MMP9 TLR1 TLR2 TLR4 TLR6
19 11.75 CCL2 TLR2 TLR4
20 11.69 HSPD1 TIRAP TLR1 TLR2 TLR4 TLR6
21 11.63 TLR1 TLR2 TLR4 TLR6
22 11.53 HSPD1 TLR2 TLR4
23 11.47 CCL2 TLR2 TLR4
24 11.45 MMP9 MPO PLAUR
25 11.44 CCL2 TLR2 TLR4
26 11.27 CCL2 MMP9 PLAUR
27 11.23 CCL2 MMP9 TLR4
28
Show member pathways
11.2 HSPD1 MMP9 TLR1 TLR2 TLR4 TLR6
29 10.85 CCL2 MMP9 TLR1 TLR2
30 10.83 CCL2 MPO

GO Terms for Pelvic Inflammatory Disease

Cellular components related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.91 CCL2 CHI3L1 CLEC3B CRP MMP9 MPO
2 extracellular space GO:0005615 9.87 CCL2 CHI3L1 CLEC3B CRP HSPD1 MMP9
3 membrane raft GO:0045121 9.46 HSPD1 TLR1 TLR2 TLR6
4 phagocytic vesicle membrane GO:0030670 9.43 TLR1 TLR2 TLR6
5 lipopolysaccharide receptor complex GO:0046696 8.96 HSPD1 TLR4
6 Toll-like receptor 1-Toll-like receptor 2 protein complex GO:0035354 8.62 TLR1 TLR2

Biological processes related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 58)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.97 CCL2 CHI3L1 TIRAP TLR4
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.9 TIRAP TLR2 TLR4 TLR6
3 cellular response to interferon-gamma GO:0071346 9.87 CCL2 TLR2 TLR4
4 defense response to Gram-positive bacterium GO:0050830 9.86 CRP TIRAP TLR2
5 positive regulation of inflammatory response GO:0050729 9.85 HSPD1 TLR2 TLR4
6 positive regulation of interleukin-6 production GO:0032755 9.83 HSPD1 TLR2 TLR4
7 response to lipopolysaccharide GO:0032496 9.83 HSPD1 MPO TIRAP TLR2 TLR4
8 positive regulation of tumor necrosis factor production GO:0032760 9.82 TIRAP TLR2 TLR4
9 lipopolysaccharide-mediated signaling pathway GO:0031663 9.77 CCL2 TLR2 TLR4
10 positive regulation of interferon-beta production GO:0032728 9.72 TLR2 TLR4
11 negative regulation of intrinsic apoptotic signaling pathway GO:2001243 9.72 MMP9 PLAUR
12 positive regulation of T cell activation GO:0050870 9.72 CCL2 HSPD1
13 TRIF-dependent toll-like receptor signaling pathway GO:0035666 9.72 TLR4 TLR6
14 positive regulation of interleukin-8 production GO:0032757 9.72 TIRAP TLR2 TLR4
15 positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9.71 MMP9 PLAUR
16 positive regulation of chemokine production GO:0032722 9.71 TLR2 TLR4
17 microglial cell activation GO:0001774 9.71 TLR2 TLR6
18 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.71 TLR4 TLR6
19 negative regulation of growth of symbiont in host GO:0044130 9.71 MPO TIRAP
20 positive regulation of interleukin-10 production GO:0032733 9.71 HSPD1 TLR2 TLR4
21 positive regulation of interleukin-8 secretion GO:2000484 9.7 TLR1 TLR2
22 positive regulation of reactive oxygen species biosynthetic process GO:1903428 9.7 TLR4 TLR6
23 positive regulation of interferon-alpha production GO:0032727 9.7 HSPD1 TLR4
24 I-kappaB phosphorylation GO:0007252 9.69 TLR2 TLR4
25 activation of NF-kappaB-inducing kinase activity GO:0007250 9.69 CHI3L1 TIRAP TLR6
26 macrophage activation GO:0042116 9.68 TLR1 TLR4
27 positive regulation of tumor necrosis factor biosynthetic process GO:0042535 9.68 TLR1 TLR4
28 cellular response to oxidised low-density lipoprotein particle stimulus GO:0140052 9.68 TLR4 TLR6
29 interleukin-1 beta secretion GO:0050702 9.67 TLR4 TLR6
30 positive regulation of NLRP3 inflammasome complex assembly GO:1900227 9.67 TLR4 TLR6
31 positive regulation of macrophage activation GO:0043032 9.67 HSPD1 TLR4 TLR6
32 positive regulation of toll-like receptor 2 signaling pathway GO:0034137 9.66 TIRAP TLR1
33 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:2001268 9.65 MMP9 PLAUR
34 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.65 CCL2 TLR2 TLR4
35 cellular response to diacyl bacterial lipopeptide GO:0071726 9.64 TLR2 TLR6
36 toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 9.63 TLR2 TLR6
37 cellular response to bacterial lipopeptide GO:0071221 9.63 TIRAP TLR2
38 cell activation GO:0001775 9.63 TLR1 TLR2 TLR6
39 cellular response to triacyl bacterial lipopeptide GO:0071727 9.62 TLR1 TLR2
40 nitric oxide metabolic process GO:0046209 9.62 TLR2 TLR6
41 toll-like receptor signaling pathway GO:0002224 9.62 TLR1 TLR2 TLR4 TLR6
42 positive regulation of oxidative stress-induced neuron death GO:1903223 9.61 TLR4 TLR6
43 toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 9.61 TLR1 TLR2
44 detection of diacyl bacterial lipopeptide GO:0042496 9.58 TLR2 TLR6
45 detection of triacyl bacterial lipopeptide GO:0042495 9.58 TLR1 TLR2
46 cellular response to lipoteichoic acid GO:0071223 9.58 TIRAP TLR2 TLR4
47 positive regulation of cellular response to macrophage colony-stimulating factor stimulus GO:1903974 9.57 TLR2 TLR4
48 response to bacterial lipoprotein GO:0032493 9.56 TLR2 TLR6
49 positive regulation of interleukin-12 production GO:0032735 9.56 HSPD1 TIRAP TLR2 TLR4
50 inflammatory response GO:0006954 9.56 CCL2 CHI3L1 CRP TIRAP TLR1 TLR2

Molecular functions related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.87 CRP MMP9 TIRAP TLR1 TLR2 TLR4
2 signaling receptor binding GO:0005102 9.73 CCL2 PLAUR TLR4 TLR6
3 protein heterodimerization activity GO:0046982 9.73 HSPD1 TIRAP TLR1 TLR2 TLR4 TLR6
4 signaling receptor activity GO:0038023 9.55 PLAUR TLR1 TLR2 TLR4 TLR6
5 lipopolysaccharide binding GO:0001530 9.54 HSPD1 TLR2 TLR4
6 lipopolysaccharide receptor activity GO:0001875 9.4 TLR2 TLR4
7 lipopeptide binding GO:0071723 9.13 TLR1 TLR2 TLR6
8 Toll-like receptor 2 binding GO:0035663 8.8 TIRAP TLR1 TLR6

Sources for Pelvic Inflammatory Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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