MCID: PLV003
MIFTS: 55

Pelvic Inflammatory Disease

Categories: Reproductive diseases

Aliases & Classifications for Pelvic Inflammatory Disease

Summaries for Pelvic Inflammatory Disease

MedlinePlus : 43 Pelvic inflammatory disease (PID) is an infection and inflammation of the uterus, ovaries, and other female reproductive organs. It causes scarring in these organs. This can lead to infertility, ectopic pregnancy, pelvic pain, abscesses, and other serious problems. PID is the most common preventable cause of infertility in the United States. Gonorrhea and chlamydia, two sexually transmitted diseases, are the most common causes of PID. Other bacteria can also cause it. You are at greater risk if you Are sexually active and younger than 25 Have more than one sex partner Douche Some women have no symptoms. Others have pain in the lower abdomen, fever, smelly vaginal discharge, irregular bleeding, and pain during intercourse or urination. Doctors diagnose PID with a physical exam, lab tests, and imaging tests. Antibiotics can cure PID. Early treatment is important. Waiting too long increases the risk of infertility. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Pelvic Inflammatory Disease, also known as pid, is related to salpingitis and chlamydia, and has symptoms including fever, pelvic pain and pruritus. An important gene associated with Pelvic Inflammatory Disease is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. The drugs Iodine and Povidone have been mentioned in the context of this disorder. Affiliated tissues include ovary, uterus and testes, and related phenotypes are cardiovascular system and hematopoietic system

CDC : 3 Untreated sexually transmitted diseases (STDs) can cause pelvic inflammatory disease (PID), a serious condition, in women. 1 in 8 women with a history of PID experience difficulties getting pregnant. You can prevent PID if you know how to protect yourself.

Wikipedia : 76 Pelvic inflammatory disease or pelvic inflammatory disorder (PID) is an infection of the upper part of... more...

Related Diseases for Pelvic Inflammatory Disease

Diseases related to Pelvic Inflammatory Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 170)
# Related Disease Score Top Affiliating Genes
1 salpingitis 32.5 CD40LG HSPD1
2 chlamydia 31.2 CD40LG CRP HSPD1 TLR2 TLR4
3 peritonitis 31.1 CCL2 CRP MPO TLR2
4 epididymitis 30.6 CD40LG CRP
5 urethritis 30.2 CD40LG HSPD1 TLR6
6 brucellosis 30.0 CD40LG CRP TLR4
7 appendicitis 30.0 CRP MMP9 MPO
8 myocardial infarction 28.0 CCL2 CD40LG CRP MMP9 MPO TLR4
9 pneumonia 27.9 CCL2 CD40LG CRP MPO TLR2 TLR4
10 fitz-hugh-curtis syndrome 11.5
11 pick disease of brain 10.9
12 benign multicystic peritoneal mesothelioma 10.9
13 chronic meningitis 10.8 CRP MMP9
14 acalculous cholecystitis 10.8 CD40LG CRP
15 ocular toxoplasmosis 10.7 CD40LG TLR1
16 acute maxillary sinusitis 10.7 CD40LG CRP
17 japanese spotted fever 10.7 CD40LG CRP
18 prosthetic joint infection 10.6 TLR2 TLR4
19 dressler's syndrome 10.6 CD40LG CRP
20 dental abscess 10.6 CRP TLR4
21 coccidioidomycosis 10.6 CD40LG TLR4
22 eosinophilic meningitis 10.5 CD40LG MMP9
23 neurosyphilis 10.5 TLR1 TLR2 TLR6
24 takayasu arteritis 10.5 CD40LG CRP MMP9
25 acute cervicitis 10.5 TLR2 TLR4
26 bacterial meningitis 10.5 CRP MMP9 TLR2
27 cat-scratch disease 10.4 CD40LG HSPD1
28 central nervous system vasculitis 10.4 CD40LG CRP
29 fallopian tube disease 10.4 CD40LG HSPD1
30 autoimmune inner ear disease 10.4 MMP9 MPO
31 pyelitis 10.4 CD40LG CRP TLR4
32 bartonellosis 10.4 CD40LG HSPD1
33 scleritis 10.4 CCL2 MMP9
34 legionnaires' disease 10.4 CD40LG TLR4 TLR6
35 bronchiolitis 10.4 CD40LG TLR1 TLR4
36 mycobacterium abscessus 10.4 TLR1 TLR2
37 melioidosis 10.4 TLR1 TLR2 TLR4
38 aortitis 10.4 CRP MPO
39 septic arthritis 10.4 CRP TLR2 TLR4
40 keratitis, hereditary 10.3 MMP9 TLR2 TLR4
41 trench fever 10.3 CD40LG TLR2 TLR4
42 intussusception 10.3 CD40LG CRP
43 mononeuritis of upper limb and mononeuritis multiplex 10.3 CD40LG MPO
44 anterior uveitis 10.3 CCL2 TLR2
45 myositis fibrosa 10.3 TLR2 TLR4
46 spondylitis 10.3 CD40LG CHI3L1 CRP
47 middle ear disease 10.3 CD40LG TLR2 TLR4
48 legionellosis 10.3 CD40LG TLR2 TLR4
49 mediastinitis 10.3 CRP MPO
50 monoclonal paraproteinemia 10.3 CD40LG MPO

Comorbidity relations with Pelvic Inflammatory Disease via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Pelvic Inflammatory Disease:



Diseases related to Pelvic Inflammatory Disease

Symptoms & Phenotypes for Pelvic Inflammatory Disease

UMLS symptoms related to Pelvic Inflammatory Disease:


fever, pelvic pain, pruritus

MGI Mouse Phenotypes related to Pelvic Inflammatory Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.86 TIRAP TLR2 CD40LG TLR4 CRP HLA-DQB1
2 hematopoietic system MP:0005397 9.85 TIRAP TLR1 TLR2 CD40LG TLR4 CHI3L1
3 immune system MP:0005387 9.73 TLR1 TLR2 CCL2 CD40LG TLR4 CHI3L1
4 muscle MP:0005369 9.1 TLR2 TLR4 HLA-DQB1 HSPD1 MMP9 MPO

Drugs & Therapeutics for Pelvic Inflammatory Disease

Drugs for Pelvic Inflammatory Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 114)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Iodine Approved, Investigational Phase 4,Phase 3,Not Applicable 7553-56-2 807
2
Povidone Approved Phase 4,Phase 3,Not Applicable 9003-39-8
3
Povidone-iodine Approved Phase 4,Phase 3,Not Applicable 25655-41-8
4
Levofloxacin Approved, Investigational Phase 4,Phase 3,Not Applicable 100986-85-4 149096
5
Ofloxacin Approved Phase 4,Phase 3,Not Applicable 82419-36-1 4583
6
Clindamycin Approved, Vet_approved Phase 4,Not Applicable 18323-44-9 29029
7
Metronidazole Approved Phase 4,Phase 3,Phase 2,Not Applicable 443-48-1 4173
8
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
9 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3 979-32-8
10
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
11
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
12
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
13
Polyestradiol phosphate Approved Phase 4,Phase 3 28014-46-2
14
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 564-25-0 54671203
15
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
16
Azithromycin Approved Phase 4,Phase 3,Not Applicable 83905-01-5 55185 447043
17
Copper Approved, Investigational Phase 4,Not Applicable 7440-50-8 27099
18
Cefazolin Approved Phase 4,Not Applicable 25953-19-9 656510 33255
19 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
20 Anti-Infective Agents, Local Phase 4,Phase 3,Not Applicable
21 Blood Substitutes Phase 4,Phase 3
22 cadexomer iodine Phase 4,Phase 3,Not Applicable
23 Micronutrients Phase 4,Phase 3,Not Applicable
24 Plasma Substitutes Phase 4,Phase 3
25 Trace Elements Phase 4,Phase 3,Not Applicable
26 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
27 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Not Applicable
28 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Not Applicable
29 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Phase 3,Not Applicable
30 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Not Applicable
31 Renal Agents Phase 4,Phase 3,Not Applicable
32 Topoisomerase Inhibitors Phase 4,Phase 3,Not Applicable
33 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
34 Antitubercular Agents Phase 4,Phase 2,Phase 3,Not Applicable
35 Contraceptive Agents Phase 4,Phase 3,Not Applicable
36 Contraceptives, Oral Phase 4,Phase 3,Not Applicable
37 Clindamycin palmitate Phase 4,Not Applicable
38 Clindamycin phosphate Phase 4,Not Applicable
39 Gentamicins Phase 4,Phase 2,Phase 3,Not Applicable
40 Contraceptives, Oral, Combined Phase 4,Phase 3
41 Estradiol 17 beta-cypionate Phase 4,Phase 3
42 Estradiol 3-benzoate Phase 4,Phase 3
43 Fluoroquinolones Phase 4,Phase 3
44 Norgestimate, ethinyl estradiol drug combination Phase 4,Phase 3
45 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3
46 Antimalarials Phase 4,Phase 2,Not Applicable
47 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1
48
Ceftriaxone Approved Phase 3,Phase 2 73384-59-5 5479530 5361919
49
Ampicillin Approved, Vet_approved Phase 2, Phase 3,Not Applicable 69-53-4 6249
50
Epinephrine Approved, Vet_approved Phase 3 51-43-4 5816

Interventional clinical trials:

(show top 50) (show all 103)
# Name Status NCT ID Phase Drugs
1 Preoperative Vaginal Cleansing With Povidone Iodine and the Risk of Post Cesarean Endometritis Unknown status NCT02693483 Phase 4 10% povidone iodine
2 To Compare Ofloxacin With Azitromycin for Pelvic Inflammatory Disease (PID) Treatment Completed NCT01241110 Phase 4 Ofloxacin group A, Azitromycin group B;azitromycin
3 Moxifloxacin Versus Ofloxacin Plus Metronidazole in Uncomplicated Pelvic Inflammatory Disease: Multicenter Randomized Controlled Trials Completed NCT01799356 Phase 4 Moxifloxacin;Ofloxacin;Metronidazole
4 Doxycycline Prophylaxis at Vacuum Aspiration Trial Completed NCT00547170 Phase 4 Doxycycline pre-operatively;Doxycycline post-operatively
5 Stage Matched Intervention to Increase Dual Method Use Completed NCT00436306 Phase 4
6 Does Preoperative Vaginal Preparation With Povidone-iodine Before Cesarean Delivery Reduce the Risk of Endometritis? Completed NCT01437228 Phase 4 povidone- iodine solution.;placebo
7 A Trial to Assess the Efficacy and Safety of Morinidazole in Women With Pelvic Inflammatory Disease Recruiting NCT03391440 Phase 4 morinidazole
8 Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries Recruiting NCT03248297 Phase 4 Azithromycin;Azithromycin and amoxicillin;Placebo
9 Comparison Between Intrauterine Contraceptive Device Insertion During Cesarean Section Vs Conventional Application Enrolling by invitation NCT02674139 Phase 4
10 Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection Not yet recruiting NCT03532464 Phase 4 azithromycin;doxycycline
11 Antibiotics During Intrauterine Balloon Tamponade Placement Not yet recruiting NCT03478163 Phase 4 CeFAZolin 1000 MG;Clindamycin 900 MG in 6 ML Injection
12 Treatment Utility of Postpartum Antibiotics in Chorioamnionitis Terminated NCT01585129 Phase 4 Postpartum Antibiotics;No postpartum antibiotics
13 Comparison Study of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis Withdrawn NCT01721616 Phase 4 Azithromycin;Cefazolin
14 A Trial Comparing Moxifloxacin Versus Levofloxacin Plus Metronidazole In Uncomplicated Pelvic Inflammatory Disease Completed NCT00453349 Phase 3 Moxifloxacin (Avelox, BAY12-8039);Levofloxacin & Metronidazole
15 Uncomplicated Pelvic Inflammatory Disease. Treatment With Moxifloxacin. Completed NCT00683865 Phase 3 Ofloxacin;Avelox (Moxifloxacin, BAY12-8039)
16 Study Of Azithromycin Intravenous Formulation Against Pelvic Inflammatory Disease (PID) In Japan Completed NCT00871494 Phase 3 Azithromycin
17 A Phase 3 Study Of Intravenous Metronidazole For Intrabdominal Infection Completed NCT01473836 Phase 3 Metronidazole;Ceftriaxone sodium
18 Home Screening for Chlamydia Surveillance Completed NCT00177437 Phase 3
19 Vasopressin Versus Epinephrine in Myomectomy Completed NCT01861015 Phase 3 Epinephrine;Vasopressin
20 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Completed NCT01633294 Phase 2, Phase 3 Ampicillin + gentamicin
21 Chlorhexidine Gluconate vs Povidone-Iodine Vaginal Cleansing Solution Prior to Cesarean Delivery Recruiting NCT02915289 Phase 3
22 Empiric Therapy of Mucopurulent Cervicitis (MPC) Terminated NCT01072136 Phase 3 Azithromycin;Cefixime
23 The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section Unknown status NCT02742948 Phase 2 ceftriaxone
24 The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID) Completed NCT01160640 Phase 2 Ceftriaxone;Doxycycline;Metronidazole;Placebo Oral Capsule
25 An Investigational Agent for the Treatment of Complicated Intra-Abdominal Infections or Acute Pelvic Infections (0826-038) Completed NCT00092170 Phase 2 MK0826, ertapenem sodium;Comparator: Ticarcillin/Clavulanate
26 The Clinical Effect of Fuke Qianjin Capsule on Chronic Pelvic Pain Caused by Pelvic Inflammation Recruiting NCT03251560 Phase 2 Fuke Qianjin capsule;Placebo oral capsule
27 The Efficacy and Safety of the Xue-Fu-Zhu-Yu Capsule in Treatment of Qi Stagnation and Blood Stasis Syndrome. Recruiting NCT03091634 Phase 2 xue-fu-zhu-yu capsule;xue-fu-zhu-yu capsule simulated agent
28 Clinical Research of TCM on Pelvic Inflammatory Disease Sequelae Not yet recruiting NCT02972151 Phase 2 Comprehensive treatment of TCM
29 Ultrasound-guided Hydrosalpinx Aspiration During Egg Collection Terminated NCT00566956 Phase 2
30 First in Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and to Explore Pharmacodynamics of BAY1834845 Completed NCT03054402 Phase 1 BAY1834845;Placebo
31 Pharmacokinetics and Safety of Ertapenem in the Postpartum Period Terminated NCT01587495 Phase 1 Ertapenem
32 Feasibility of Four-dimensional Hysterosalpingo-contrast Sonography With SonoVue for Assessment of Tubal Patency Unknown status NCT02505555
33 A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing Unknown status NCT01880918
34 RCT(Randomized Clinical Trial ) of Antibiotic Therapy in Chronic Endometritis Unknown status NCT02648698 Not Applicable antibiotics;placebo
35 Single or Triple Uterine Tourniquet at Myomectomy Unknown status NCT02392585 Not Applicable
36 Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth: a Randomized Controlled Trial Unknown status NCT01945450 Not Applicable Antibiotic prophylaxis;Ampicillin;Gentamycin;Clindamycin
37 A Multicenter Analysis of Levonorgestrel-Intrauterine System (LNG-IUS) Use in the Postpartum Period Unknown status NCT01161095 Not Applicable
38 Rate of Pelvic Inflammatory Disease at St. Michael's Hospital Completed NCT00783419
39 Community-Based Trial of Screening for Chlamydia Trachomatis to Prevent Pelvic Inflammatory Disease Completed NCT00115388 Not Applicable
40 Drug Use Investigation Of Azithromycin IV For Pneumonia Or Pelvic Inflammatory Disease (Regulatory Post Marketing Commitment Plan) Completed NCT01671280 Azithromycin IV
41 Improving Primary Care Follow-up for Patients With Pelvic Inflammatory Disease Completed NCT01299259 Not Applicable
42 Technology Enhanced Community Health Nursing (TECH-N) Study Completed NCT01640379 Not Applicable
43 The Role of Novel Organisms in Acute Endometritis Completed NCT01236131
44 To Compare the Strategies of Universal Antibiotic Prophylaxis Versus Screen-and-treat in Reducing Infective Complications and Re-infection in Women Who Undergo Termination of Pregnancy Completed NCT01842100 Not Applicable Universal antibiotic prophylaxis
45 Immunopathogenesis of Chlamydia Completed NCT00607659
46 Complement Diagnosis of Acute Appendicitis Completed NCT03450642
47 Risk of Acute Liver Injury in Users of Antimicrobials Completed NCT01434173 Moxifloxacin (Avelox, BAY12-8039);Amoxicillin, Amoxicillin plus clavulanic acid, Cefuroxime, Clarithromycin, Doxycycline, Levofloxacin, Telithromycin
48 Recurrent Bacterial Vaginosis and Vaginal Acidifying Gel Trial Completed NCT00545181 Not Applicable Vaginal acidifying gel (RepHresh);Metronidazole control
49 Home Sampling Versus Conventional Sampling for Screening of Urogenital Chlamydia Trachomatis in Young Men and Women. Completed NCT00283127 Not Applicable
50 A Comparison of Narrow Band Imaging (NBI) and Standard White Light Laporoscopy to Detect Endometriosis Completed NCT01464775 Not Applicable

Search NIH Clinical Center for Pelvic Inflammatory Disease

Cochrane evidence based reviews: pelvic inflammatory disease

Genetic Tests for Pelvic Inflammatory Disease

Anatomical Context for Pelvic Inflammatory Disease

MalaCards organs/tissues related to Pelvic Inflammatory Disease:

41
Ovary, Uterus, Testes, Liver, Placenta, Neutrophil, T Cells

Publications for Pelvic Inflammatory Disease

Articles related to Pelvic Inflammatory Disease:

(show top 50) (show all 639)
# Title Authors Year
1
Gonococcal and Chlamydial Cases of Pelvic Inflammatory Disease at 2 Canadian Sexually Transmitted Infection Clinics, 2004 to 2014: A Retrospective Cross-sectional Review. ( 29465704 )
2018
2
Toll-like receptor variants and cervical Atopobium vaginae infection in women with pelvic inflammatory disease. ( 29286178 )
2018
3
Sustained Simultaneous Delivery of Metronidazole and Doxycycline From Polycaprolactone Matrices Designed for Intravaginal Treatment of Pelvic Inflammatory Disease. ( 29100864 )
2018
4
Impact of the Levonorgestrel-Releasing Intrauterine System on the Progression of Chlamydia trachomatis Infection to Pelvic Inflammatory Disease in a Baboon Model. ( 29253201 )
2018
5
Patient Satisfaction and Treatment Adherence for Urban Adolescents and Young Adults with Pelvic Inflammatory Disease. ( 29756068 )
2018
6
Trends in pelvic inflammatory disease emergency department visits, United States, 2006-2013. ( 29045851 )
2018
7
Risk of pelvic inflammatory disease after intrauterine insemination: a systematic review. ( 29287941 )
2018
8
LC-Q-TOF-MS based plasma metabolomic profile of subclinical pelvic inflammatory disease: A pilot study. ( 29709453 )
2018
9
Acupuncture for chronic pelvic inflammatory disease: A systematic review protocol. ( 29595670 )
2018
10
Discovery of Blood Transcriptional Endotypes in Women with Pelvic Inflammatory Disease. ( 29531169 )
2018
11
Anti-Inflammatory Effect of Feiyangchangweiyan Capsule on Rat Pelvic Inflammatory Disease through JNK/NF-<i>I_</i>B Pathway. ( 29681986 )
2018
12
Pelvic Inflammatory Disease (PID) ( 29763134 )
2018
13
Repeat Chlamydia Diagnoses Increase the Hazard of Pelvic Inflammatory Disease among U.S. Army females: A Retrospective Cohort Analysis. ( 29870505 )
2018
14
Predictive factors for emergent surgical intervention in patients with ovarian endometrioma hospitalized for pelvic inflammatory disease: A retrospective observational study. ( 29171117 )
2018
15
Rates of pelvic inflammatory disease and ectopic pregnancy in Australia, 2009-2014: ecological analysis of hospital data. ( 29720385 )
2018
16
Acute pelvic inflammatory disease as a rare cause of acute small bowel obstruction. ( 29560794 )
2018
17
Pelvic inflammatory disease risk following negative results from chlamydia nucleic acid amplification tests (NAATs) versus non-NAATs in Denmark: A retrospective cohort. ( 29293503 )
2018
18
The effect of antibiotic prophylaxis for acute pelvic inflammatory disease after hysterosalpingography: a retrospective cohort study. ( 29239678 )
2018
19
Safety and efficacy of tigecycline in complicated and uncomplicated pelvic inflammatory disease. ( 29917214 )
2018
20
Risk of Pelvic Inflammatory Disease in Relation to Chlamydia and Gonorrhea Testing, Repeat Testing, and Positivity: A Population-Based Cohort Study. ( 29136127 )
2018
21
Risk of high-grade serous ovarian cancer associated with pelvic inflammatory disease, parity and breast cancer. ( 29935395 )
2018
22
Microbiota changes impact on sexually transmitted infections and the development of pelvic inflammatory disease. ( 29452257 )
2018
23
2017 European guideline for the management of pelvic inflammatory disease. ( 29198181 )
2018
24
Comparison of the population excess fraction of Chlamydia trachomatis infection on pelvic inflammatory disease at 12-months in the presence and absence of chlamydia testing and treatment: Systematic review and retrospective cohort analysis. ( 28199392 )
2017
25
Prevalence of Pelvic Inflammatory Disease in Sexually Experienced Women of Reproductive Age - United States, 2013-2014. ( 28125569 )
2017
26
Mesenchymal Stem Cells in Restoration of Fertility at Experimental Pelvic Inflammatory Disease. ( 28928773 )
2017
27
What Antibiotic Regimen Is Most Efficacious in Treating Pelvic Inflammatory Disease? ( 28822590 )
2017
28
Pelvic Inflammatory Disease and the Risk of Ovarian Cancer and Borderline Ovarian Tumors: A Pooled Analysis of 13 Case-Control Studies. ( 27941069 )
2017
29
Anti-inflammatory Effects of the Natural Compounds Cortex Phellodendri and Humulus japonicus on Pelvic Inflammatory Disease in Mice. ( 28824307 )
2017
30
A Community Based Study on Pelvic Inflammatory Disease in Postmenopausal Females: Microbiological Spectrum and Socio-Demographic Correlates. ( 28511414 )
2017
31
Pelvic inflammatory disease and the risk of ovarian cancer: a meta-analysis. ( 28342087 )
2017
32
Curative effect of Jin'gangteng capsule combined with Kangfuxiaoyan suppository in the treatment of chronic pelvic inflammatory disease. ( 29105625 )
2017
33
Is Pelvic Inflammatory Disease a Risk Factor for Ovarian Cancer? ( 27672055 )
2017
34
Efficacy and safety of morinidazole in pelvic inflammatory disease: results of a multicenter, double-blind, randomized trial. ( 28265816 )
2017
35
Postpartum tubo-ovarian abscess, likely arising from pelvic inflammatory disease during pregnancy. ( 28408537 )
2017
36
Clinical characteristics of genital chlamydia infection in pelvic inflammatory disease. ( 28086838 )
2017
37
Pelvic inflammatory disease and salpingitis: incidence of primary and repeat episodes in England. ( 27678278 )
2017
38
Pelvic inflammatory disease. ( 28098673 )
2017
39
Socioeconomic status of parents and the occurrence of pelvic inflammatory disease among undergraduates attending Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria. ( 28762367 )
2017
40
The potential role of infectious agents and pelvic inflammatory disease in ovarian carcinogenesis. ( 28529540 )
2017
41
Current perspectives in the USA on the diagnosis and treatment of pelvic inflammatory disease in adolescents. ( 28721112 )
2017
42
Severe Sepsis and Acute Myocardial Dysfunction in an Adolescent with Chlamydia Trachomatis Pelvic Inflammatory Disease: A Case Report. ( 29037929 )
2017
43
Antibiotic therapy for pelvic inflammatory disease. ( 28436019 )
2017
44
How to differentiate acute pelvic inflammatory disease from acute appendicitis ? A decision tree based on CT findings. ( 28894927 )
2017
45
Pelvic inflammatory disease due to Streptococcus pneumoniae. ( 28807391 )
2017
46
Erroneously Suspected Ovarian Cancer in a 38-Year-Old Woman with Pelvic Inflammatory Disease and Chlamydia. ( 29391959 )
2017
47
Whole-Exome Sequencing to Identify Novel Biological Pathways Associated With Infertility After Pelvic Inflammatory Disease. ( 27898568 )
2017
48
Pelvic Inflammatory Disease in a Pediatric Emergency Department: Epidemiology and Treatment. ( 28441241 )
2017
49
Evaluation of pelvic inflammatory disease potential in cholinesterase inhibitor pesticide-exposed females. ( 28497326 )
2017
50
Early screening for Chlamydia trachomatis in young women for primary prevention of pelvic inflammatory disease (i-Predict): study protocol for a randomised controlled trial. ( 29132441 )
2017

Variations for Pelvic Inflammatory Disease

Expression for Pelvic Inflammatory Disease

Search GEO for disease gene expression data for Pelvic Inflammatory Disease.

Pathways for Pelvic Inflammatory Disease

Pathways related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show all 28)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.78 CCL2 CD40LG CHI3L1 CRP HLA-DQB1 MMP9
2
Show member pathways
13.34 CD40LG HLA-DQB1 TIRAP TLR1 TLR2 TLR4
3
Show member pathways
13.3 CCL2 CD40LG TIRAP TLR1 TLR2 TLR4
4
Show member pathways
12.9 CCL2 TIRAP TLR1 TLR2 TLR4 TLR6
5
Show member pathways
12.59 CD40LG TLR1 TLR2 TLR4 TLR6
6
Show member pathways
12.45 MMP9 TIRAP TLR2 TLR4
7
Show member pathways
12.38 TIRAP TLR1 TLR2 TLR4 TLR6
8
Show member pathways
12.32 TIRAP TLR1 TLR2 TLR4 TLR6
9 12.31 CCL2 CD40LG MPO TLR1 TLR2 TLR6
10
Show member pathways
12.17 TLR1 TLR2 TLR4 TLR6
11
Show member pathways
12.17 TIRAP TLR1 TLR2 TLR4 TLR6
12
Show member pathways
12.16 CD40LG HLA-DQB1 TLR2 TLR4
13
Show member pathways
12.09 TIRAP TLR1 TLR2 TLR4 TLR6
14 12.07 MMP9 TLR1 TLR2 TLR4 TLR6
15 12.01 HLA-DQB1 MPO TLR2 TLR4 TLR6
16
Show member pathways
11.96 CD40LG TIRAP TLR1 TLR2 TLR4 TLR6
17
Show member pathways
11.95 TLR1 TLR2 TLR4 TLR6
18 11.89 CCL2 MMP9 TLR4
19 11.78 CD40LG TIRAP TLR4
20 11.78 CCL2 HLA-DQB1 TLR2 TLR4
21 11.74 TLR1 TLR2 TLR4 TLR6
22 11.52 HSPD1 TLR2 TLR4
23 11.44 CCL2 TLR2 TLR4
24 11.42 HLA-DQB1 HSPD1 TIRAP TLR1 TLR2 TLR4
25 11.36 CCL2 CD40LG TLR2 TLR4
26 11.06 CCL2 CD40LG MMP9 TLR4
27 10.85 CCL2 MMP9 TLR1 TLR2
28 10.84 CCL2 MPO

GO Terms for Pelvic Inflammatory Disease

Cellular components related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.56 CCL2 CD40LG CHI3L1 CLEC3B CRP HSPD1
2 phagocytic vesicle membrane GO:0030670 9.43 TLR1 TLR2 TLR6
3 lipopolysaccharide receptor complex GO:0046696 9.16 HSPD1 TLR4
4 Toll-like receptor 1-Toll-like receptor 2 protein complex GO:0035354 8.62 TLR1 TLR2

Biological processes related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 52)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.97 CCL2 CHI3L1 TIRAP TLR4
2 defense response to bacterium GO:0042742 9.96 MPO TLR1 TLR4 TLR6
3 response to lipopolysaccharide GO:0032496 9.95 MPO TIRAP TLR2 TLR4
4 immune response GO:0006955 9.95 CCL2 CD40LG HLA-DQB1 TLR1 TLR2 TLR4
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.88 CD40LG TIRAP TLR2 TLR4 TLR6
6 defense response to Gram-positive bacterium GO:0050830 9.86 CRP TIRAP TLR2
7 positive regulation of interleukin-6 production GO:0032755 9.82 HSPD1 TLR2 TLR4
8 positive regulation of tumor necrosis factor production GO:0032760 9.81 TIRAP TLR2 TLR4
9 lipopolysaccharide-mediated signaling pathway GO:0031663 9.77 CCL2 TLR2 TLR4
10 toll-like receptor signaling pathway GO:0002224 9.76 TLR1 TLR2 TLR4 TLR6
11 positive regulation of interleukin-8 production GO:0032757 9.74 TIRAP TLR2 TLR4
12 activation of NF-kappaB-inducing kinase activity GO:0007250 9.72 CHI3L1 TIRAP TLR6
13 positive regulation of interferon-beta production GO:0032728 9.71 TLR2 TLR4
14 positive regulation of T cell activation GO:0050870 9.71 CCL2 HSPD1
15 positive regulation of endothelial cell apoptotic process GO:2000353 9.71 CCL2 CD40LG
16 positive regulation of chemokine production GO:0032722 9.71 TLR2 TLR4
17 cell activation GO:0001775 9.71 TLR1 TLR2 TLR6
18 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.7 TLR4 TLR6
19 negative regulation of growth of symbiont in host GO:0044130 9.7 MPO TIRAP
20 microglial cell activation GO:0001774 9.7 TLR2 TLR6
21 positive regulation of macrophage activation GO:0043032 9.7 HSPD1 TLR4 TLR6
22 positive regulation of interleukin-8 secretion GO:2000484 9.69 TLR1 TLR2
23 positive regulation of reactive oxygen species biosynthetic process GO:1903428 9.69 TLR4 TLR6
24 positive regulation of interferon-alpha production GO:0032727 9.69 HSPD1 TLR4
25 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.69 CCL2 TLR2 TLR4
26 I-kappaB phosphorylation GO:0007252 9.68 TLR2 TLR4
27 positive regulation of tumor necrosis factor biosynthetic process GO:0042535 9.68 TLR1 TLR4
28 T-helper 1 type immune response GO:0042088 9.68 TLR4 TLR6
29 macrophage activation GO:0042116 9.67 TLR1 TLR4
30 interleukin-1 beta secretion GO:0050702 9.67 TLR4 TLR6
31 cellular response to lipoteichoic acid GO:0071223 9.67 TIRAP TLR2 TLR4
32 positive regulation of interleukin-10 production GO:0032733 9.67 CD40LG HSPD1 TLR2 TLR4
33 positive regulation of NLRP3 inflammasome complex assembly GO:1900227 9.66 TLR4 TLR6
34 cellular response to oxidised low-density lipoprotein particle stimulus GO:0140052 9.65 TLR4 TLR6
35 positive regulation of toll-like receptor 2 signaling pathway GO:0034137 9.65 TIRAP TLR1
36 positive regulation of interleukin-12 production GO:0032735 9.65 CD40LG HSPD1 TIRAP TLR2 TLR4
37 cellular response to diacyl bacterial lipopeptide GO:0071726 9.63 TLR2 TLR6
38 toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 9.63 TLR2 TLR6
39 toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 9.62 TLR1 TLR2
40 cellular response to triacyl bacterial lipopeptide GO:0071727 9.62 TLR1 TLR2
41 regulation of cytokine secretion GO:0050707 9.62 TLR1 TLR2 TLR4 TLR6
42 nitric oxide metabolic process GO:0046209 9.61 TLR2 TLR6
43 positive regulation of oxidative stress-induced neuron death GO:1903223 9.61 TLR4 TLR6
44 positive regulation of interleukin-6 biosynthetic process GO:0045410 9.61 TIRAP TLR1 TLR6
45 inflammatory response GO:0006954 9.61 CCL2 CD40LG CHI3L1 CRP TIRAP TLR1
46 detection of triacyl bacterial lipopeptide GO:0042495 9.59 TLR1 TLR2
47 response to bacterial lipoprotein GO:0032493 9.58 TLR2 TLR6
48 detection of diacyl bacterial lipopeptide GO:0042496 9.58 TLR2 TLR6
49 cellular response to bacterial lipopeptide GO:0071221 9.46 TIRAP TLR1 TLR2 TLR6
50 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.1 HSPD1 TIRAP TLR1 TLR2 TLR4 TLR6

Molecular functions related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein heterodimerization activity GO:0046982 9.77 TIRAP TLR1 TLR2 TLR4 TLR6
2 signaling receptor activity GO:0038023 9.56 TLR1 TLR2 TLR4 TLR6
3 lipopolysaccharide binding GO:0001530 9.33 HSPD1 TLR2 TLR4
4 lipopolysaccharide receptor activity GO:0001875 9.32 TLR2 TLR4
5 lipopeptide binding GO:0071723 9.13 TLR1 TLR2 TLR6
6 Toll-like receptor 2 binding GO:0035663 8.8 TIRAP TLR1 TLR6

Sources for Pelvic Inflammatory Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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