MCID: PLV001
MIFTS: 34

Pelvic Lipomatosis

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Pelvic Lipomatosis

MalaCards integrated aliases for Pelvic Lipomatosis:

Name: Pelvic Lipomatosis 12 76 53 44 15 73
Excess of Mature Unencapsulated Fatty Tissue in the Pelvis 53

Classifications:



External Ids:

Disease Ontology 12 DOID:3927
MeSH 44 C535549
NCIt 50 C27486
SNOMED-CT 68 190802005
UMLS 73 C0406608

Summaries for Pelvic Lipomatosis

NIH Rare Diseases : 53 Pelvic lipomatosis is a rare disease of unknown cause, characterized by overgrowth of mature, non-cancerous fat cells in the pelvic region. The symptoms of pelvic lipomatosis are related to the compression of the urinary system (urinary frequency, dysuria, nocturia, and hematuria), lower intestinal tract (constipation, tenesmus, rectal bleeding, and ribbon-like stools with mucus), and vascular system (edema of lower extremities). Pelvic lipomatosis has been linked to chronic lower urinary tract infections, obesity, and endocrine dysfunction. Treatment usually seeks to alleviate symptoms, especially kidney obstruction and end stage renal disease. While most cases are not progressive, upper-tract urinary surgery may be needed for those with severe symptoms and/or evidence of urinary obstruction with deterioration of the kidney function.  

MalaCards based summary : Pelvic Lipomatosis, also known as excess of mature unencapsulated fatty tissue in the pelvis, is related to pelvic lipomatosis with crossed renal ectopia and lipomatosis, and has symptoms including abdominal pain, back pain and constipation. An important gene associated with Pelvic Lipomatosis is HMGA2 (High Mobility Group AT-Hook 2), and among its related pathways/superpathways are Immune response IL-2 activation and signaling pathway and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include kidney, skin and prostate.

Wikipedia : 76 Pelvic lipomatosis is a rare disease that is most often seen in older obese black men with hypertension.... more...

Related Diseases for Pelvic Lipomatosis

Graphical network of the top 20 diseases related to Pelvic Lipomatosis:



Diseases related to Pelvic Lipomatosis

Symptoms & Phenotypes for Pelvic Lipomatosis

UMLS symptoms related to Pelvic Lipomatosis:


abdominal pain, back pain, constipation

Drugs & Therapeutics for Pelvic Lipomatosis

Search Clinical Trials , NIH Clinical Center for Pelvic Lipomatosis

Cochrane evidence based reviews: pelvic lipomatosis

Genetic Tests for Pelvic Lipomatosis

Anatomical Context for Pelvic Lipomatosis

MalaCards organs/tissues related to Pelvic Lipomatosis:

41
Kidney, Skin, Prostate, Bone

Publications for Pelvic Lipomatosis

Articles related to Pelvic Lipomatosis:

(show top 50) (show all 107)
# Title Authors Year
1
Urodynamic characteristics of pelvic lipomatosis with glandular cystitis patients correlate with morphologic alterations of the urinary system and disease severity. ( 28763116 )
2017
2
Value of Multimode Sonography for Assessment of Pelvic Lipomatosis Compared With Computed Tomography. ( 27091913 )
2016
3
Pelvic lipomatosis. ( 27418096 )
2016
4
Pelvic lipomatosis: Bladder sparing extirpation of pelvic mass to relieve bladder storage dysfunction symptoms and pelvic pain. ( 25247089 )
2014
5
Image characteristics of computer tomography urography in pelvic lipomatosis. ( 24482720 )
2014
6
Laparoscopy assisted 'U' configuration bilateral ileal ureter in pelvic lipomatosis with bilateral ureteric obstruction. ( 24078511 )
2013
7
Measuring diagnostic accuracy of imaging parameters in pelvic lipomatosis. ( 22749803 )
2012
8
Pelvic lipomatosis: US and CT diagnosis. ( 22970068 )
2012
9
Rare etiology of obstructive uropathy: pelvic lipomatosis. ( 20215833 )
2010
10
Answer to case of the month #126. Pelvic lipomatosis in association with cystitis glandularis. ( 18286907 )
2007
11
CT findings of pelvic lipomatosis of nerve. ( 15728036 )
2005
12
Fatal acute pulmonary embolism in a patient with pelvic lipomatosis after surgery performed after transatlantic airplane travel. ( 15385344 )
2004
13
The importance of re-evaluation in patients with cystitis glandularis associated with pelvic lipomatosis: a case report. ( 15464926 )
2004
14
Pelvic lipomatosis complicating ovarian cyst removal: a case report. ( 15285320 )
2004
15
Pelvic lipomatosis detected on bone scintigraphy. ( 15150024 )
2004
16
Fat necrosis mimicking liposarcoma in a patient with pelvic lipomatosis. CT findings. ( 12639777 )
2003
17
Pelvic lipomatosis in a child. ( 12372895 )
2002
18
Pelvic lipomatosis associated with proliferative cystitis occurring in two brothers. ( 11927334 )
2002
19
Pelvic lipomatosis presenting as uraemic encephalopathy. ( 11321859 )
2001
20
Achondroplasia associated with pelvic lipomatosis. ( 10459943 )
1999
21
Achondroplasia associated with pelvic lipomatosis. ( 10459944 )
1999
22
Pelvic lipomatosis associated with proliferative cystitis: case report and review of the Japanese literature. ( 10221865 )
1999
23
The radiographic diagnosis of pelvic lipomatosis. ( 9531109 )
1997
24
The use of an ultrasonic assisted lipectomy device for the treatment of obstructive pelvic lipomatosis. ( 8693634 )
1996
25
Pelvic lipomatosis. ( 10829955 )
1995
26
Cytogenetic findings in crossed renal ectopia with pelvic lipomatosis. ( 8370589 )
1993
27
Re: Pelvic lipomatosis associated with cystitis glandularis and adenocarcinoma of the bladder. ( 1569691 )
1992
28
Renal scintigraphy in a patient with pelvic lipomatosis. ( 1505127 )
1992
29
Pelvic lipomatosis or pericystitis plastica? ( 1422694 )
1992
30
Crossed renal ectopia with pelvic lipomatosis: a new syndrome involving chromosome 1. ( 1511984 )
1992
31
Pelvic lipomatosis: a review of its diagnosis and management. ( 1856914 )
1991
32
A case of pelvic lipomatosis presenting with edema of the lower extremities. ( 1798216 )
1991
33
Pelvic lipomatosis. ( 2070217 )
1991
34
Pelvic lipomatosis associated with cystitis glandularis and adenocarcinoma of the bladder. ( 1988733 )
1991
35
Pelvic lipomatosis in a female: diagnosis and initial therapy. ( 2024384 )
1991
36
Pelvic lipomatosis with cystitis cystica, cystitis glandularis and adenocarcinoma of the bladder: first reported case. ( 2183756 )
1990
37
A case of cystitis glandularis with associated pelvic lipomatosis: ultrasound evaluation. ( 2174927 )
1990
38
A rare case of iliac vein obstruction: pelvic lipomatosis. ( 2348931 )
1990
39
Pelvic lipomatosis in the Proteus syndrome: a further diagnostic sign. ( 2226574 )
1990
40
Pelvic lipomatosis: diagnosis and characterization by magnetic resonance imaging. ( 3245101 )
1988
41
Pelvic lipomatosis: 35-year experience. ( 3361678 )
1988
42
Pelvic lipomatosis. ( 3690190 )
1987
43
Pelvic lipomatosis: the nuclear magnetic resonance appearance and associated vesicoureteral reflux. ( 3669174 )
1987
44
Computed tomography of pelvic lipomatosis. Report of a case. ( 3751680 )
1986
45
Proteus syndrome: report of two cases with pelvic lipomatosis. ( 4069870 )
1985
46
Large bowel obstruction due to pelvic lipomatosis. ( 3986485 )
1985
47
Radical prostatectomy in the presence of pelvic lipomatosis. ( 6699991 )
1984
48
Pelvic lipomatosis causing constriction of the lower urinary tract and the rectum. Case report. ( 6494832 )
1984
49
CAT scan of the month. Pelvic lipomatosis. ( 6503281 )
1984
50
Pelvic lipomatosis with ureteral encasement and recurrent thrombophlebitis. ( 6879267 )
1983

Variations for Pelvic Lipomatosis

Expression for Pelvic Lipomatosis

Search GEO for disease gene expression data for Pelvic Lipomatosis.

Pathways for Pelvic Lipomatosis

GO Terms for Pelvic Lipomatosis

Cellular components related to Pelvic Lipomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 senescence-associated heterochromatin focus GO:0035985 8.62 HMGA1 HMGA2

Biological processes related to Pelvic Lipomatosis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.69 CXCL14 IL15 IL2
2 regulation of signaling receptor activity GO:0010469 9.65 CXCL14 IL15 IL2
3 cell-cell signaling GO:0007267 9.58 CXCL14 IL15 IL2
4 response to virus GO:0009615 9.52 HMGA1 HMGA2
5 positive regulation of inflammatory response GO:0050729 9.49 IL15 IL2
6 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.46 IL15 IL2
7 positive regulation of T cell proliferation GO:0042102 9.43 IL15 IL2
8 base-excision repair GO:0006284 9.37 HMGA1 HMGA2
9 positive regulation of cellular senescence GO:2000774 9.32 HMGA1 HMGA2
10 positive regulation of interleukin-17 production GO:0032740 9.26 IL15 IL2
11 positive regulation of tissue remodeling GO:0034105 9.16 IL15 IL2
12 senescence-associated heterochromatin focus assembly GO:0035986 8.96 HMGA1 HMGA2
13 oncogene-induced cell senescence GO:0090402 8.62 HMGA1 HMGA2

Molecular functions related to Pelvic Lipomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-(apurinic or apyrimidinic site) endonuclease activity GO:0003906 8.96 HMGA1 HMGA2
2 AT DNA binding GO:0003680 8.62 HMGA1 HMGA2

Sources for Pelvic Lipomatosis

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17 ExPASy
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
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74 UMLS via Orphanet
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