MCID: PMP009
MIFTS: 30

Pemphigus Erythematosus

Categories: Skin diseases, Rare diseases

Aliases & Classifications for Pemphigus Erythematosus

MalaCards integrated aliases for Pemphigus Erythematosus:

Name: Pemphigus Erythematosus 59 55 73
Senear-Usher Syndrome 59
Seborrheic Pemphigus 59

Classifications:

Orphanet: 59  
Rare skin diseases


External Ids:

Orphanet 59 ORPHA79480
ICD10 via Orphanet 34 L10.4
UMLS via Orphanet 74 C0263312
ICD10 33 L10.4
UMLS 73 C0263312

Summaries for Pemphigus Erythematosus

MalaCards based summary : Pemphigus Erythematosus, also known as senear-usher syndrome, is related to pemphigus and pemphigus vulgaris. An important gene associated with Pemphigus Erythematosus is DSP (Desmoplakin), and among its related pathways/superpathways are Keratinization and Apoptotic cleavage of cellular proteins. Affiliated tissues include skin, and related phenotypes are abnormal blistering of the skin and pruritus

Wikipedia : 76 Pemphigus erythematosus (also known as \"Senear–Usher syndrome\") is simply a localized form of... more...

Related Diseases for Pemphigus Erythematosus

Diseases related to Pemphigus Erythematosus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 29)
# Related Disease Score Top Affiliating Genes
1 pemphigus 29.9 DSG3 DSP
2 pemphigus vulgaris 29.3 DSG3 DSP
3 pemphigus vulgaris, familial 10.1
4 lupus erythematosus 10.1
5 thymoma 10.0
6 usher syndrome 10.0
7 retinitis pigmentosa-deafness syndrome 10.0
8 systemic lupus erythematosus 9.9
9 myasthenia gravis 9.8
10 myasthenia gravis congenital 9.8
11 pemphigus foliaceus 9.7
12 discoid lupus erythematosus 9.7
13 primary biliary cirrhosis 9.7
14 cutaneous lupus erythematosus 9.7
15 dermatitis 9.7
16 contact dermatitis 9.7
17 allergic contact dermatitis 9.7
18 biliary cirrhosis, primary, 1 9.7
19 pyoderma 9.7
20 pyoderma gangrenosum 9.7
21 dermatophytosis 9.7
22 aging 9.7
23 burn scar 9.7
24 burns 9.7
25 primary biliary cholangitis 9.7
26 bullous skin disease 9.5 DSG3 DSP
27 paraneoplastic pemphigus 9.5 DSG3 DSP
28 bullous pemphigoid 9.2 DSG3 DSP
29 skin disease 9.0 DSG3 DSP

Graphical network of the top 20 diseases related to Pemphigus Erythematosus:



Diseases related to Pemphigus Erythematosus

Symptoms & Phenotypes for Pemphigus Erythematosus

Human phenotypes related to Pemphigus Erythematosus:

59 32
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abnormal blistering of the skin 59 32 hallmark (90%) Very frequent (99-80%) HP:0008066
2 pruritus 59 32 hallmark (90%) Very frequent (99-80%) HP:0000989
3 skin vesicle 59 32 hallmark (90%) Very frequent (99-80%) HP:0200037
4 acantholysis 59 32 hallmark (90%) Very frequent (99-80%) HP:0100792
5 crusting erythematous dermatitis 59 32 hallmark (90%) Very frequent (99-80%) HP:0007473

Drugs & Therapeutics for Pemphigus Erythematosus

Search Clinical Trials , NIH Clinical Center for Pemphigus Erythematosus

Genetic Tests for Pemphigus Erythematosus

Anatomical Context for Pemphigus Erythematosus

MalaCards organs/tissues related to Pemphigus Erythematosus:

41
Skin

Publications for Pemphigus Erythematosus

Articles related to Pemphigus Erythematosus:

(show top 50) (show all 75)
# Title Authors Year
1
Unusually extensive scalp ulcerations manifested in pemphigus erythematosus. ( 29469763 )
2018
2
Pruritic, Pink Scaling Plaques on the Face and Trunk. Pemphigus erythematosus. ( 26267852 )
2015
3
Pemphigus erythematosus relapse associated with atorvastatin intake. ( 25258514 )
2014
4
Cutaneous dirt-adherent disease on a base of pemphigus erythematosus. ( 24117279 )
2013
5
Microsporum canis infection mimics pemphigus erythematosus. ( 23723503 )
2013
6
Induction of Skin Lesions by Ultraviolet B Irradiation in a Case of Pemphigus Erythematosus. ( 24356850 )
2013
7
The IgG "lupus-band" deposition pattern of pemphigus erythematosus: association with the desmoglein 1 ectodomain as revealed by 3 cases. ( 22801864 )
2012
8
Cefuroxime-induced pemphigus erythematosus in a young boy. ( 19077088 )
2009
9
Topical 0.03% tacrolimus for treatment of pemphigus erythematosus in a Korea Jindo dog. ( 18460840 )
2008
10
Treatment of refractory pemphigus erythematosus with rituximab. ( 19126029 )
2008
11
Mucocutaneous pemphigus vulgaris carrying high-titre antidesmoglein 1 antibodies with skin lesions resembling pemphigus erythematosus. ( 17983457 )
2008
12
Pemphigus erythematosus in a chow chow. ( 16454386 )
2005
13
Control of childhood pemphigus erythematosus with steroids and azathioprine. ( 14746642 )
2004
14
Topical 0.1% tacrolimus for the treatment of discoid lupus erythematosus and pemphigus erythematosus in dogs. ( 14736903 )
2004
15
Pemphigus erythematosus associated with anti-DNA antibodies and multiple anti-ENA antibodies: a case report. ( 12729095 )
2003
16
Pemphigus erythematosus associated with thymoma: a case report. ( 10500920 )
1999
17
Pemphigus erythematosus: detection of anti-desmoglein-1 antibodies by ELISA. ( 10559598 )
1999
18
Trichophyton dermatophytosis--a disease easily confused with pemphigus erythematosus. ( 9262861 )
1997
19
Systemic lupus erythematosus, pemphigus erythematosus, and thymoma in the same patient. ( 19078051 )
1996
20
Pemphigus erythematosus in a five-year-old child. ( 7962746 )
1994
21
Pemphigus erythematosus induced by ceftazidime. ( 8407098 )
1993
22
Superficial erosions with some oozing and marked crusting. Pemphigus erythematosus (PE). ( 8481026 )
1993
23
Regional variation in the expression of pemphigus foliaceus, pemphigus erythematosus, and pemphigus vulgaris antigens in human skin. ( 1991976 )
1991
24
Multiple crusted plaques in a woman with systemic lupus erythematosus. Pemphigus erythematosus (PE). ( 1929469 )
1991
25
The role of cyclosporine A in the treatment of pemphigus erythematosus. ( 1816136 )
1991
26
Pemphigus erythematosus and herpetic infection due to HSV type II. ( 1794181 )
1991
27
Desmoplakin I and II in acantholytic dermatoses: preservation in pemphigus vulgaris and pemphigus erythematosus and dissolution in Hailey-Hailey's disease and Darier's disease. ( 2054341 )
1991
28
Pemphigus erythematosus with suprabasilar acantholysis and lichenoid tissue reaction or a combination of pemphigus vulgaris and lupus erythematosus: a new entity? ( 1743386 )
1991
29
Penicillamine-induced pemphigus erythematosus. ( 2186003 )
1990
30
Pemphigus erythematosus resembling multiple seborrheic keratoses. ( 2138876 )
1990
31
Pemphigus erythematosus: a report of five cases with review of literature. ( 3249166 )
1988
32
Concurrent features of cutaneous lupus erythematosus and pemphigus erythematosus following myasthenia gravis and thymoma. ( 3819095 )
1987
33
Pemphigus erythematosus in the light of fluorescent microscopy. ( 3133295 )
1987
34
Pemphigus erythematosus: a unique association with systemic lupus erythematosus. ( 3769550 )
1986
35
Pemphigus erythematosus. Senear-Usher syndrome. ( 3888871 )
1985
36
Pemphigus erythematosus, primary biliary cirrhosis, and D-penicillamine: report of a case. ( 4008691 )
1985
37
Pemphigus erythematosus: clinical and histo-immunological studies in two unusual cases. ( 6204491 )
1984
38
Pemphigus erythematosus. Presentation of four cases and review of literature. ( 6371067 )
1984
39
Photo-induction of lesions in a patient with pemphigus erythematosus. ( 6531279 )
1984
40
"An unusual type of pemphigus combining features of lupus erythematosus" by Senear and Usher, June 1926. Commentary: Pemphigus erythematosus, a unique member of the pemphigus group. ( 6753755 )
1982
41
Pyoderma gangrenosum associated with transient acantholytic dermatosis (pemphigus erythematosus-like) and paraproteinemia. ( 6164226 )
1981
42
Pemphigus erythematosus and thymoma. ( 7357885 )
1980
43
Two cases of penicillamine-induced pemphigus erythematosus. ( 157890 )
1979
44
Successful use of Chinese medicine and corticosteroid for pemphigus erythematosus (Senear-Usher syndrome). ( 543490 )
1979
45
Pemphigus erythematosus and heroin addiction. ( 659032 )
1978
46
Pathogenesis of pemphigus erythematosus. ( 326203 )
1977
47
Pemphigus erythematosus-like rash in a patient on penicillamine. ( 851751 )
1977
48
Pemphigus erythematosus in a six-year-old girl. ( 1186675 )
1975
49
Pemphigus erythematosus provoked by allergic contact dermatitis. Occurrence many years after thymoma removal. ( 4584307 )
1973
50
Pemphigus erythematosus confined to the post-burn scar. ( 4592127 )
1973

Variations for Pemphigus Erythematosus

Expression for Pemphigus Erythematosus

Search GEO for disease gene expression data for Pemphigus Erythematosus.

Pathways for Pemphigus Erythematosus

Pathways related to Pemphigus Erythematosus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.41 DSG3 DSP
2
Show member pathways
10.69 DSG3 DSP

GO Terms for Pemphigus Erythematosus

Cellular components related to Pemphigus Erythematosus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 9.16 DSG3 DSP
2 cornified envelope GO:0001533 8.96 DSG3 DSP
3 desmosome GO:0030057 8.62 DSG3 DSP

Biological processes related to Pemphigus Erythematosus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 8.96 DSG3 DSP
2 cornification GO:0070268 8.62 DSG3 DSP

Sources for Pemphigus Erythematosus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....