MCID: PMP008
MIFTS: 27

Pemphigus Vegetans

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Pemphigus Vegetans

MalaCards integrated aliases for Pemphigus Vegetans:

Name: Pemphigus Vegetans 58 54 17 70 32

Classifications:

Orphanet: 58  
Rare skin diseases


External Ids:

ICD10 32 L10.1
ICD10 via Orphanet 33 L10.1
UMLS via Orphanet 71 C0263316 C0406647
Orphanet 58 ORPHA79479
UMLS 70 C0263316

Summaries for Pemphigus Vegetans

MalaCards based summary : Pemphigus Vegetans is related to pemphigus and pemphigus vulgaris, familial. An important gene associated with Pemphigus Vegetans is DSG1 (Desmoglein 1), and among its related pathways/superpathways are Developmental Biology and Keratinization. Affiliated tissues include tongue, and related phenotype is integument.

Wikipedia : 73 Pemphigus vegetans is a localized form of pemphigus vulgaris. in which there is a localized vegetating... more...

Related Diseases for Pemphigus Vegetans

Diseases related to Pemphigus Vegetans via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)
# Related Disease Score Top Affiliating Genes
1 pemphigus 31.4 PPL DSG1 DSC3
2 pemphigus vulgaris, familial 30.4 PPL DSG1 DSC3
3 pemphigus foliaceus 30.2 PPL DSG1
4 impetigo 30.1 DSG1 DSC3
5 paraneoplastic pemphigus 29.7 PPL DSG1 DSC3
6 iga pemphigus 29.5 PPL DSG1 DSC3
7 paronychia 10.2
8 impetigo herpetiformis 10.2
9 alcohol dependence 10.1
10 autoimmune disease 10.1
11 keratosis 10.1
12 papilloma 10.1
13 acrodermatitis 10.1
14 pyoderma 10.1
15 stomatitis 10.1
16 leukemia, chronic lymphocytic 10.0
17 dowling-degos disease 1 10.0
18 keratosis, seborrheic 10.0
19 lymphoma, hodgkin, classic 10.0
20 immune deficiency disease 10.0
21 myasthenia gravis 10.0
22 gitelman syndrome 10.0
23 thymoma, familial 10.0
24 branchiootic syndrome 1 10.0
25 lymphoma, non-hodgkin, familial 10.0
26 peripheral vascular disease 10.0
27 exanthem 10.0
28 inflammatory bowel disease 10.0
29 thrombosis 10.0
30 pemphigoid 10.0
31 fissured tongue 10.0
32 cryptococcosis 10.0
33 marasmus 10.0
34 balanitis 10.0
35 glanders 10.0
36 toxic shock syndrome 10.0
37 candidiasis 10.0
38 vascular disease 10.0
39 chronic mucocutaneous candidiasis 10.0
40 dermatitis 10.0
41 thymoma 10.0
42 cellulitis 10.0
43 nail disease 10.0
44 syphilis 10.0
45 inverted follicular keratosis 10.0
46 cocaine abuse 10.0
47 herpes simplex 10.0
48 molluscum contagiosum 10.0
49 fasciitis 10.0
50 necrotizing fasciitis 10.0

Graphical network of the top 20 diseases related to Pemphigus Vegetans:



Diseases related to Pemphigus Vegetans

Symptoms & Phenotypes for Pemphigus Vegetans

MGI Mouse Phenotypes related to Pemphigus Vegetans:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.8 DSC3 DSG1 PPL

Drugs & Therapeutics for Pemphigus Vegetans

Search Clinical Trials , NIH Clinical Center for Pemphigus Vegetans

Genetic Tests for Pemphigus Vegetans

Anatomical Context for Pemphigus Vegetans

MalaCards organs/tissues related to Pemphigus Vegetans:

40
Tongue

Publications for Pemphigus Vegetans

Articles related to Pemphigus Vegetans:

(show top 50) (show all 285)
# Title Authors PMID Year
1
Canine hyperplastic intraepidermal pustular and suprabasal acantholytic dermatosis with features of human pemphigus vegetans. 61 54
17606523 2007
2
Intraepithelial Autoimmune Blistering Dermatoses: Clinical Features and Diagnosis. 61
33684498 2021
3
Flame Figures in Linear Immunoglobulin A Bullous Dermatosis Secondary to Parvovirus B19 Infection. 61
32472771 2021
4
Is 640 nm high-fluence visible red light a valuable adjunct for treating pemphigus vegetans? A single case report. 61
32359024 2020
5
Deep pemphigus (pemphigus vulgaris, pemphigus vegetans and paraneoplastic pemphigus) in dogs, cats and horses: a comprehensive review. 61
33228633 2020
6
Immune serological diagnosis of pemphigus. 61
33228340 2020
7
Pemphigus vegetans localised to the soles of both feet: Successful clearance with intralesional corticosteroid. 61
32602553 2020
8
Hallopeau type of pemphigus vegetans, an unusual clinical presentation of an infrequent disease. 61
33147676 2020
9
Features and associated factors of bacterial skin infections in hospitalized patients with pemphigus: a single-center retrospective study. 61
33032608 2020
10
Pemphigus vegetans with paronychia-like changes resistant to rituximab therapy. 61
32367637 2020
11
Visual Dermatology: Pemphigus Vegetans. 61
32602731 2020
12
Visual Dermatology: Scalp Involvement in Pemphigus Vegetans. 61
32442016 2020
13
A case of pemphigus vegetans presenting with hoarseness of voice. 61
31573685 2020
14
[Pemphigus vegetans]. 61
31843224 2020
15
A Rare Case of Extensive Pemphigus Vegetans. 61
32055517 2020
16
Cutaneous pemphigus vegetans co-occurring with oral pemphigus vulgaris. 61
32074154 2020
17
Nail Involvement during Pemphigus. 61
31799264 2019
18
Pemphigus vegetans with isolated involvement of the nose and chest: rare variant of pemphigus vulgaris. 61
33272516 2019
19
Verrucous lesions over external genitalia as a presenting feature of pemphigus vegetans. 61
31922111 2019
20
Pemphigus vulgaris. 61
31365654 2019
21
Pemphigus vulgaris. 61
33272532 2019
22
Pemphigus vegetans initiating on the finger and nail. 61
30977725 2019
23
Autoimmune skin disease among dermatology outpatients in Botswana: a retrospective review. 61
30168847 2019
24
Pemphigus vegetans with isolated involvement of the nose and chest: rare variant of pemphigus vulgaris. 61
31644626 2019
25
Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus. 61
31275323 2019
26
[Unexpected positive outcome following rituximab treatment in a patient with pemphigus vegetans resistant to conventional therapies: a case report]. 61
31223391 2019
27
Pemphigus Vegetans in the Inguinal Folds. 61
29937062 2018
28
Elevated serum eosinophil cationic protein and transforming growth factor-α levels in a patient with pemphigus vegetans. 61
29862541 2018
29
Pemphigus vegetans presenting as serpiginous oral, esophageal and genital mucosal ulcers undiagnosed for 3 years. 61
30156214 2018
30
Cutaneous Bacteriological Profile in Patients with Pemphigus. 61
30078873 2018
31
Pemphigus vegetans arising in umbilicus: Successful clearance with intralesional steroid. 61
28879869 2018
32
Reduced IgG anti-desmocollin autoantibody titre and concomitant improvement in a patient with pemphigus vegetans. 61
29336313 2018
33
Pemphigus vegetans with the manifestations of acrodermatitis continua: A rare variant. 61
29058326 2018
34
Chronic Paronychia and Onychomadesis in Pemphigus Vegetans: An Unusual Presentation in a Rare Autoimmune Disease. 61
29560011 2018
35
Pemphigus Vegetans Confined to the Face and Scalp. 61
29551118 2018
36
Routine detection of serum antidesmocollin autoantibodies is only useful in patients with atypical pemphigus. 61
28815795 2017
37
Atypical Clinical and Serological Manifestation of Pemphigus Vegetans: A Case Report and Review of the Literature. 61
28559810 2017
38
Successful monotherapy of pemphigus vegetans with minocycline and nicotinamide. 61
27600093 2017
39
Clinical and immunological studies of 49 cases of various types of intercellular IgA dermatosis and 13 cases of classical subcorneal pustular dermatosis examined at Kurume University. 61
27258999 2017
40
The Rare Case of Pemphigus Vegetans in Association with Malnutrition Children in the Multidisciplinary Management. 61
28559814 2017
41
A study of clinical, histopathological and direct immunofluorescence diagnosis in pemphigus group Utility of direct immunofluorescence. 61
28471236 2017
42
[Perianal pemphigus vegetans]. 61
27371358 2016
43
IgG/IgA pemphigus representing pemphigus vegetans caused by low titres of IgG and IgA antibodies to desmoglein 3 and IgA antibodies to desmocollin 3. 61
25865168 2016
44
Pyodermatitis vegetans of the vulva. 61
27617602 2016
45
Pemphigus in North-Western Yemen: A therapeutic study of 75 cases. 61
27088959 2016
46
Pemphigus vegetans presenting as a verrucous plaque on the finger. 61
26204944 2016
47
Cerebriform Cutaneous Lesions in Pemphigus Vegetans. 61
27057025 2016
48
"Pemphigus vegetans of the scalp". 61
25339136 2016
49
Pemphigus vegetans associated with Gitelman syndrome. 61
26515865 2015
50
Pemphigus vegetans localized to unusual sites. 61
26261132 2015

Variations for Pemphigus Vegetans

Expression for Pemphigus Vegetans

Search GEO for disease gene expression data for Pemphigus Vegetans.

Pathways for Pemphigus Vegetans

Pathways related to Pemphigus Vegetans according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.34 PPL DSG1 DSC3
2
Show member pathways
11.25 PPL DSG1 DSC3

GO Terms for Pemphigus Vegetans

Cellular components related to Pemphigus Vegetans according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 9.33 PPL DSG1 DSC3
2 cell-cell junction GO:0005911 9.26 DSG1 DSC3
3 cornified envelope GO:0001533 9.13 PPL DSG1 DSC3
4 desmosome GO:0030057 8.8 PPL DSG1 DSC3

Biological processes related to Pemphigus Vegetans according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein stabilization GO:0050821 9.32 DSG1 DSC3
2 cell-cell adhesion GO:0098609 9.26 DSG1 DSC3
3 homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 9.16 DSG1 DSC3
4 keratinization GO:0031424 9.13 PPL DSG1 DSC3
5 cornification GO:0070268 8.8 PPL DSG1 DSC3

Molecular functions related to Pemphigus Vegetans according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 gamma-catenin binding GO:0045295 8.62 DSG1 DSC3

Sources for Pemphigus Vegetans

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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