Aliases & Classifications for Penicilliosis

MalaCards integrated aliases for Penicilliosis:

Name: Penicilliosis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050288

Summaries for Penicilliosis

Disease Ontology : 12 An opportunistic mycosis that has material basis in Penicillium marneffei, results in systemic infection and has symptom fever, has symptom anemia, has symptom weight loss, has symptom lymphadenopathy, has symptom hepatosplenomegaly, has symptom respiratory signs, and has symptom skin lesions.

MalaCards based summary : Penicilliosis is related to histoplasmosis and cryptococcal meningitis, and has symptoms including fever, anemia and weight loss. An important gene associated with Penicilliosis is CD4 (CD4 Molecule), and among its related pathways/superpathways are Tuberculosis and Th2 Differentiation Pathway. Affiliated tissues include bone marrow, skin and brain.

Wikipedia : 73 Talaromycosis (formerly known as penicilliosis or penicillosis) is an infection caused by Talaromyces... more...

Related Diseases for Penicilliosis

Diseases related to Penicilliosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 151)
# Related Disease Score Top Affiliating Genes
1 histoplasmosis 30.3 IFNG CLEC7A CD4
2 cryptococcal meningitis 29.9 IFNG CD4
3 candidiasis 29.8 IFNG CLEC7A CARD9
4 cryptococcosis 29.6 IFNG CLEC7A CD4 CARD9
5 mucormycosis 29.3 IFNG CLEC7A CD4 CARD9
6 opportunistic mycosis 29.3 IFNG CLEC7A CD4 CARD9
7 immune deficiency disease 10.3
8 acquired immunodeficiency syndrome 10.2
9 necrotic uveal melanoma 10.2 IFNG CD4
10 panophthalmitis 10.2 IFNG CD4
11 ocular tuberculosis 10.2 IFNG CD4
12 pericardial tuberculosis 10.2 IFNG CD4
13 suppurative lymphadenitis 10.2 IFNG CD4
14 skin sarcoidosis 10.2 IFNG CD4
15 opportunistic bacterial infectious disease 10.2 IFNG CD4
16 nocardiosis 10.2 IFNG CD4
17 gastrointestinal tuberculosis 10.2 IFNG CD4
18 intestinal tuberculosis 10.2 IFNG CD4
19 oral tuberculosis 10.2 IFNG CD4
20 lymph node tuberculosis 10.2 IFNG CD4
21 lung abscess 10.2 IFNG CD4
22 abdominal tuberculosis 10.2 IFNG CD4
23 retinitis pigmentosa 46 10.2 IFNG CD4
24 nickel allergic contact dermatitis 10.2 IFNG CD4
25 scleral disease 10.2 IFNG CD4
26 tungiasis 10.2 IFNG CD4
27 miliary tuberculosis 10.2 IFNG CD4
28 mucocutaneous leishmaniasis 10.2 IFNG CD4
29 chorioretinitis 10.2 IFNG CD4
30 choroiditis 10.2 IFNG CD4
31 fungal meningitis 10.2 IFNG CD4
32 strongyloidiasis 10.2 IFNG CD4
33 tuberculoid leprosy 10.2 IFNG CD4
34 macs syndrome 10.2 IFNG CD4
35 central nervous system vasculitis 10.2 IFNG CD4
36 hepatic tuberculosis 10.2 IFNG CD4
37 multidrug-resistant tuberculosis 10.2 IFNG CD4
38 phagocyte bactericidal dysfunction 10.2 IFNG CD4
39 pleural tuberculosis 10.2 IFNG CD4
40 cytomegalovirus retinitis 10.2 IFNG CD4
41 lichen disease 10.2 IFNG CD4
42 multicentric castleman disease 10.2 IFNG CD4
43 autoimmune gastritis 10.2 IFNG CD4
44 rhinosporidiosis 10.2 CLEC7A CD4
45 parasitic ichthyosporea infectious disease 10.2 CLEC7A CD4
46 cryptosporidiosis 10.2 IFNG CD4
47 cutaneous candidiasis 10.2 CLEC7A CARD9
48 pericardium disease 10.2 IFNG CD4
49 hypersplenism 10.1 IFNG CD4
50 tinea profunda 10.1 CLEC7A CARD9

Graphical network of the top 20 diseases related to Penicilliosis:



Diseases related to Penicilliosis

Symptoms & Phenotypes for Penicilliosis

Symptoms:

12
  • fever
  • anemia
  • weight loss
  • lymphadenopathy
  • hepatosplenomegaly
  • skin lesions
  • respiratory signs

Drugs & Therapeutics for Penicilliosis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Making an Early Diagnosis of Talaromycosis - a Strategy to Reduce Morbidity and Mortality in Advanced HIV Disease in Southeast Asia Recruiting NCT04033120

Search NIH Clinical Center for Penicilliosis

Genetic Tests for Penicilliosis

Anatomical Context for Penicilliosis

MalaCards organs/tissues related to Penicilliosis:

40
Bone Marrow, Skin, Brain, Monocytes

Publications for Penicilliosis

Articles related to Penicilliosis:

(show top 50) (show all 276)
# Title Authors PMID Year
1
Tzanck cytology smear in diagnosis of cutaneous talaromycosis (penicilliosis). 61
33666044 2021
2
Rare misdiagnosed case of penicilliosis marneffei in an immunocompetent patient. 61
33100074 2020
3
Case Report: Bilateral Granulomatous Anterior Uveitis in HIV-patient with Disseminated Talaromycosis (penicilliosis) Marneffei Infection. 61
31577460 2020
4
Asymptomatic pulmonary penicilliosis with a lung mass in an HIV-infected patient. 61
32742907 2020
5
Identification and functional characterization of Penicillium marneffei major facilitator superfamily (MFS) transporters. 61
32163007 2020
6
Diagnostic laboratory immunology for talaromycosis (penicilliosis): review from the bench-top techniques to the point-of-care testing. 61
31836254 2020
7
Opportunistic penicilliosis infection causing intestinal obstruction in people living with HIV complicating antiretroviral therapy. 61
32060105 2020
8
Mycotoxicoses in veterinary medicine: Aspergillosis and penicilliosis. 61
32782737 2020
9
Talaromycosis (Penicilliosis) Due to Talaromyces (Penicillium) marneffei: Insights into the Clinical Trends of a Major Fungal Disease 60 Years After the Discovery of the Pathogen. 61
31811603 2019
10
Reflectance Confocal Microscopic Features of Skin Lesions in a Patient with Disseminated Penicilliosis. 61
31516151 2019
11
Talaromycosis (Penicilliosis): A Rare, Opportunistic Systemic Fungal Infection. 61
31516150 2019
12
Talaromyces marneffei Mp1 Protein, a Novel Virulence Factor, Carries Two Arachidonic Acid-Binding Domains To Suppress Inflammatory Responses in Hosts. 61
30670555 2019
13
A rare case of disseminated penicilliosis - first of its kind from North India. 61
30706885 2019
14
AIDS-associated disseminated talaromycosis (penicilliosis) marneffei. 61
30248229 2018
15
Comparing the profile of respiratory fungal pathogens amongst immunocompetent and immunocompromised hosts, their susceptibility pattern and correlation of various opportunistic respiratory fungal infections and their progression in relation to the CD4+T-cell counts. 61
30429396 2018
16
Talaromycosis (Penicilliosis) in a Cynomolgus Macaque. 61
29444633 2018
17
Novel Partitivirus Enhances Virulence of and Causes Aberrant Gene Expression in Talaromyces marneffei. 61
29895639 2018
18
Study on the Clinical Features and Prognosis of Penicilliosis marneffei Without Human Immunodeficiency Virus Infection. 61
29335843 2018
19
Development and characterization of an immunochromatographic test for the rapid diagnosis of Talaromyces (Penicillium) marneffei. 61
29641620 2018
20
Image Gallery: An unusual cutaneous presentation of disseminated penicilliosis marneffei in an immunocompetent patient. 61
28940264 2017
21
Acute Disseminated Talaromyces marneffei in An Immunocompetent Patient. 61
28349349 2017
22
Pneumonia due to Talaromyces marneffei in a Dog from Southern Brazil with Concomitant Canine Distemper Virus Infection. 61
28735673 2017
23
Clinical Characteristics and Prognosis of Penicilliosis Among Human Immunodeficiency Virus-Infected Patients in Eastern China. 61
28719279 2017
24
First-in-man observation of Talaromyces marneffei-transmission by organ transplantation. 61
27687582 2017
25
Penicillium marneffei infection in a HIV-Positive patient: A comparison of bronchial washing cytology and biopsy. 61
28182077 2017
26
Disseminated Penicillium marneffei infection recurrence in a non-acquired immune deficiency syndrome patient: A case report. 61
28105364 2016
27
Development and evaluation of a real-time polymerase chain reaction assay for the rapid detection of Talaromyces marneffei MP1 gene in human plasma. 61
27453379 2016
28
Ureteral obstruction secondary to disseminated penicilliosis in a German shepherd dog. 61
27928169 2016
29
Disseminated penicilliosis due to Penicillium chrysogenum in a pediatric patient with Henoch-Schönlein syndrome. 61
27596684 2016
30
Identification and functional characterization of Penicillium marneffei pleiotropic drug resistance transporters ABC1 and ABC2. 61
26782644 2016
31
Oral mycoses and other opportunistic infections in HIV: therapy and emerging problems - a workshop report. 61
27109283 2016
32
A novel inhibition ELISA for the detection and monitoring of Penicillium marneffei antigen in human serum. 61
26838686 2016
33
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for rapid identification of mold and yeast cultures of Penicillium marneffei. 61
26965891 2016
34
Endemic Mycoses: What's New About Old Diseases? 61
32288985 2016
35
Detection of Talaromyces marneffei from Fresh Tissue of an Inhalational Murine Pulmonary Model Using Nested PCR. 61
26886887 2016
36
Differences in clinical characteristics and prognosis of Penicilliosis among HIV-negative patients with or without underlying disease in Southern China: a retrospective study. 61
26573268 2015
37
Estimating the burden of fungal disease in Vietnam. 61
26449514 2015
38
The in vitro fungicidal activity of human macrophages against Penicillium marneffei is suppressed by dexamethasone. 61
26145314 2015
39
Role of Rhizomys pruinosus as a natural animal host of Penicillium marneffei in Guangdong, China. 61
25824250 2015
40
Pancytopenia and cutaneous cryptococcosis as an indicator disease of acquired immune deficiency syndrome. 61
26068355 2015
41
Subcutaneous mycoses: an aetiological study of 15 cases in a tertiary care hospital at Dibrugarh, Assam, northeast India. 61
25596859 2015
42
Serological surveillance for Penicillium marneffei infection in HIV-infected patients during 2004-2011 in Guangzhou, China. 61
25677258 2015
43
Airway obstruction caused by penicilliosis: a case report and review of the literature. 61
24973303 2015
44
A novel method of combining Periodic Acid Schiff staining with Wright-Giemsa staining to identify the pathogens Penicillium marneffei, Histoplasma capsulatum, Mucor and Leishmania donovani in bone marrow smears. 61
26136921 2015
45
Skin and subcutaneous infections in south-east Asia. 61
25706913 2015
46
Retrospective analysis of 14 cases of disseminated Penicillium marneffei infection with osteolytic lesions. 61
25656710 2015
47
A Clinical Study of Acquired Immunodeficiency Syndrome Associated Penicillium Marneffei Infection from a Non-Endemic Area in China. 61
26083736 2015
48
Disseminated penicilliosis marneffei in immunocompetent patients: a report of two cases. 61
25560026 2015
49
Penicilliosis and AIDS in Haiphong, Vietnam: evolution and predictive factors of death. 61
25391487 2014
50
Acute Abdomen Due to Penicillium marneffei: An Indicator of HIV Infection in Manipur State. 61
25386482 2014

Variations for Penicilliosis

Expression for Penicilliosis

Search GEO for disease gene expression data for Penicilliosis.

Pathways for Penicilliosis

Pathways related to Penicilliosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.05 IFNG CLEC7A CARD9
2 10.92 IFNG CD4
3 10.62 IFNG CD4
4 10.4 IFNG CD4

GO Terms for Penicilliosis

Biological processes related to Penicilliosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of phagocytosis GO:0050766 9.48 IFNG CLEC7A
2 T cell activation GO:0042110 9.46 CLEC7A CD4
3 positive regulation of nitric oxide biosynthetic process GO:0045429 9.43 IFNG CLEC7A
4 positive regulation of interleukin-12 production GO:0032735 9.4 IFNG CLEC7A
5 positive regulation of interleukin-2 production GO:0032743 9.37 CLEC7A CD4
6 positive regulation of interleukin-6 production GO:0032755 9.33 IFNG CLEC7A CARD9
7 positive regulation of stress-activated MAPK cascade GO:0032874 9.32 CLEC7A CARD9
8 macrophage differentiation GO:0030225 9.26 IFNG CD4
9 positive regulation of tumor necrosis factor production GO:0032760 9.13 IFNG CLEC7A CARD9
10 positive regulation of killing of cells of other organism GO:0051712 8.62 IFNG CLEC7A

Sources for Penicilliosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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