MCID: PNL025
MIFTS: 26

Penile Benign Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Penile Benign Neoplasm

MalaCards integrated aliases for Penile Benign Neoplasm:

Name: Penile Benign Neoplasm 12
Neoplasm of Penis 12
Penile Neoplasm 15
Penile Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11624
MeSH 43 D010412
NCIt 49 C3317
SNOMED-CT 67 126896003
UMLS 71 C0030849

Summaries for Penile Benign Neoplasm

MalaCards based summary : Penile Benign Neoplasm, also known as neoplasm of penis, is related to verrucous carcinoma and basaloid squamous cell carcinoma. An important gene associated with Penile Benign Neoplasm is LCOR (Ligand Dependent Nuclear Receptor Corepressor), and among its related pathways/superpathways are Oncogene Induced Senescence and TP53 Network. Affiliated tissues include lymph node, lung and prostate.

Related Diseases for Penile Benign Neoplasm

Diseases related to Penile Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 131)
# Related Disease Score Top Affiliating Genes
1 verrucous carcinoma 30.4 TP53 CDKN2A
2 basaloid squamous cell carcinoma 30.2 TP53 CDKN2A
3 squamous cell papilloma 30.1 TP53 CDKN2A
4 penile cancer 30.1 TP53 SCN10A PDPN HOXA3 GP5 CNDP2
5 anogenital venereal wart 29.7 TP53 GP5 CDKN2A
6 penile cancer, adult 11.3
7 penis sarcoma 11.2
8 penis squamous cell carcinoma 10.6
9 adenocarcinoma of the penis 10.6
10 male reproductive organ benign neoplasm 10.3 SLITRK2 CDKN2A
11 chronic cervicitis 10.3 GP5 CDKN2A
12 cervicitis 10.3 GP5 CDKN2A
13 prostate squamous cell carcinoma 10.3 TP53 CDKN2A
14 vulvar intraepithelial neoplasia 10.3 TP53 CDKN2A
15 endometrial squamous cell carcinoma 10.3 TP53 CDKN2A
16 ovarian seromucinous carcinoma 10.3 TP53 CDKN2A
17 esophagus verrucous carcinoma 10.3 TP53 CDKN2A
18 spitz nevus 10.3 TP53 CDKN2A
19 bizarre leiomyoma 10.3 TP53 CDKN2A
20 suppressor of tumorigenicity 3 10.3 TP53 CDKN2A
21 localized osteosarcoma 10.3 TP53 CDKN2A
22 tumor of exocrine pancreas 10.3 TP53 CDKN2A
23 glans penis cancer 10.3
24 prepuce cancer 10.3
25 oral leukoplakia 10.3 TP53 CDKN2A
26 thyroid lymphoma 10.3 TP53 CDKN2A
27 adult malignant schwannoma 10.3 TP53 CDKN2A
28 adult astrocytic tumour 10.3 TP53 CDKN2A
29 malignant spiradenoma 10.2 TP53 CDKN2A
30 bone squamous cell carcinoma 10.2 TP53 CDKN2A
31 low-grade astrocytoma 10.2 TP53 CDKN2A
32 familial retinoblastoma 10.2 TP53 CDKN2A
33 borst-jadassohn intraepidermal carcinoma 10.2 TP53 CDKN2A
34 anal squamous cell carcinoma 10.2 TP53 CDKN2A
35 neurofibrosarcoma 10.2 TP53 CDKN2A
36 megaesophagus 10.2 TP53 CDKN2A
37 nodular malignant melanoma 10.2 TP53 CDKN2A
38 nasal cavity cancer 10.2 TP53 CDKN2A
39 peritoneum cancer 10.2 TP53 CDKN2A
40 hypopharynx cancer 10.2 TP53 CDKN2A
41 supratentorial cancer 10.2 TP53 CDKN2A
42 bone osteosarcoma 10.2 TP53 LCOR
43 endocervical carcinoma 10.2 TP53 CDKN2A
44 gliomatosis cerebri 10.2 TP53 CDKN2A
45 fibrillary astrocytoma 10.2 TP53 CDKN2A
46 thoracic benign neoplasm 10.2 TP53 LCOR
47 plexiform neurofibroma 10.2 TP53 CDKN2A
48 rhabdoid cancer 10.2 TP53 CDKN2A
49 glomus tumor 10.1 TP53 CDKN2A
50 breast benign neoplasm 10.1 TP53 LCOR

Graphical network of the top 20 diseases related to Penile Benign Neoplasm:



Diseases related to Penile Benign Neoplasm

Symptoms & Phenotypes for Penile Benign Neoplasm

Drugs & Therapeutics for Penile Benign Neoplasm

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase II Trial of Cabazitaxel Chemotherapy in Relapsed Locally Advanced &/or Metastatic Carcinoma of the Penis Completed NCT03114254 Phase 2 Cabazitaxel

Search NIH Clinical Center for Penile Benign Neoplasm

Genetic Tests for Penile Benign Neoplasm

Anatomical Context for Penile Benign Neoplasm

MalaCards organs/tissues related to Penile Benign Neoplasm:

40
Lymph Node, Lung, Prostate, Pancreas, Skin, T Cells

Publications for Penile Benign Neoplasm

Articles related to Penile Benign Neoplasm:

(show top 50) (show all 75)
# Title Authors PMID Year
1
Penile metastasis from recurrent sarcoma in a teenager: a case report. 61
31477090 2019
2
Adherence to EAU guidelines on penile cancer translates into better outcomes: a multicenter international study. 61
30377813 2019
3
Primary urethral squamous cell carcinoma: a unique manifestation of a penile tumor. 61
30514142 2019
4
Role of Diffusion-Weighted Magnetic Resonance Imaging (DWMRI) in Assessment of Primary Penile Tumor Characteristics and Its Correlations With Inguinal Lymph Node Metastasis: A Prospective Study. 61
30524639 2018
5
Mitochondrial genome analysis in penile carcinoma. 61
29948632 2018
6
Para - And Intraurethral Penile Tumor - Like Condilomatosis. 61
29484001 2018
7
Squamous Cell Carcinoma of the Penis with Pulmonary Metastasis and Paraneoplastic Hypertrophic Osteopathy in a Dog. 61
28792794 2017
8
Extranodal nasal-type natural killer/T-cell lymphoma with penile involvement: a case report and review of the literature. 61
28874193 2017
9
Medullary Carcinoma of the Penis: A Distinctive HPV-related Neoplasm: A Report of 12 Cases. 61
28291123 2017
10
Tumor PD-L1 expression is correlated with increased TILs and poor prognosis in penile squamous cell carcinoma. 61
28344882 2017
11
Myxoma of the penis in an African pygmy hedgehog (Atelerix albiventris). 61
27784859 2017
12
Myiasis associated with penile carcinoma: a new trend in developing countries? 61
24893913 2017
13
Adjuvant chemotherapy is associated with improved overall survival in pelvic node-positive penile cancer after lymph node dissection: a multi-institutional study. 61
26072110 2015
14
[A Case of Sarcomatoid Carcinoma of the Penis]. 61
26153055 2015
15
Myopericytoma tumor of the glans penis. 61
26068635 2015
16
Human papillomavirus prevalence in invasive penile cancer and association with clinical outcome. 61
25150641 2015
17
[Dramatic response of penile cancer with inguinal lymph node metastases to neoadjuvant chemotherapy with paclitaxel, ifosfamide and cisplatin : a case report]. 61
25656018 2015
18
Penis keratoacanthoma transforming into squamous cell carcinoma: a rare case. 61
26885065 2015
19
[Take care of penile cancer]. 61
25195032 2014
20
Primary penile melanoma. 61
25338349 2014
21
P16INK4A immunohistochemistry for detection of human papilloma virus-associated penile squamous cell carcinoma is superior to in-situ hybridization. 61
24067458 2013
22
[Partial penectomy for penile cancer in a centenarian man]. 61
23827873 2013
23
[Spindle cell sarcoma of the penis: a case report]. 61
22874511 2012
24
Establishment and characterization of primary cell lines of squamous cell carcinoma of the penis and its metastasis. 61
22503055 2012
25
[Penile cancer--case report and literature review]. 61
22384643 2012
26
[Penile cancer in 2010: update from the Oncology Committee of the French Association of Urology: external genital organs group (CCAFU-OGE)]. 61
22118355 2011
27
High-flow priapism due to a malignant glomus tumor (glomangiosarcoma) of the corpus cavernosum. 61
19912496 2011
28
Cytopathological features of warty (condylomatous) carcinoma of the penis: a case report and distinction from other verruciform penile tumors. 61
20301209 2010
29
[Verrucous carcinoma of penis: a case report]. 61
20610928 2010
30
Functional restoration of penis with partial defect by scrotal skin flap. 61
19762052 2009
31
[Hormone refractory prostate carcinoma metastasizes to the penis: a case report]. 61
19938335 2009
32
[Hormone refractory prostate carcinoma metastasizes to the penis: a case report.] 61
19926949 2009
33
Granular cell tumor of the penis shaft: case report and literature review. 61
19601473 2009
34
Radiation therapy in the management of the primary penile tumor: an update. 61
18636264 2009
35
[A case of penile metastasis of malignant melanoma with priapism]. 61
19378827 2009
36
[Neoadjuvant and adjuvant chemotherapy with methotrexate, cisplatin and bleomycin for advanced penile cancer: a case report]. 61
18051811 2007
37
[Penile sarcoma: a rare tumor]. 61
17937344 2007
38
Distal urethral reconstruction of the glans for penile carcinoma: results of a novel technique at 1-year of followup. 61
17632177 2007
39
Urethra reconstruction following resection of penile leiomyosarcoma. 61
16624480 2006
40
[A case of spindle cell carcinoma of the penis]. 61
16363714 2005
41
[Primary penile tumor: local treatment]. 61
16382982 2005
42
Detection and expression of Epstein-Barr Virus (EBV) DNA in tissues from penile tumors in Brazil. 61
15374635 2004
43
Sarcomatoid squamous cell carcinoma of the penis: a clinical and pathological study of 5 cases. 61
15311001 2004
44
[Organ-saving treatment of penile cancer]. 61
15114748 2004
45
Penile metastasis of chondrosarcoma of the jaw. 61
12670583 2003
46
[A report of two cases of priapism with metastatic penile tumor]. 61
12056042 2002
47
[A case of extramammary Paget's disease presenting with anuria]. 61
12094717 2002
48
[Buschke-Lowenstein penile tumor]. 61
12108356 2002
49
Metastasis to the penis in a patient with squamous cell carcinoma of the lung with a review of reported cases. 61
11557125 2001
50
Tumor stage, vascular invasion and the percentage of poorly differentiated cancer: independent prognosticators for inguinal lymph node metastasis in penile squamous cancer. 61
11257655 2001

Variations for Penile Benign Neoplasm

Expression for Penile Benign Neoplasm

Search GEO for disease gene expression data for Penile Benign Neoplasm.

Pathways for Penile Benign Neoplasm

Pathways related to Penile Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.66 TP53 CDKN2A
2
Show member pathways
10.3 TP53 CDKN2A
3 9.97 TP53 CDKN2A

GO Terms for Penile Benign Neoplasm

Biological processes related to Penile Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 replicative senescence GO:0090399 8.62 TP53 CDKN2A

Molecular functions related to Penile Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 disordered domain specific binding GO:0097718 8.62 TP53 CDKN2A

Sources for Penile Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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