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MCID: PNL012
MIFTS: 47

Penile Cancer

Categories: Cancer diseases, Rare diseases, Reproductive diseases, Skin diseases
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Aliases & Classifications for Penile Cancer

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MalaCards integrated aliases for Penile Cancer:

Name: Penile Cancer 11 14 75
Penis Carcinoma 11 14 71
Malignant Neoplasm of Penis 71 31
Penile Carcinoma 11 16
Penile Neoplasms 43 71
Penile Neoplasm 11 16
Malignant Neoplasm of Body of Penis 11
Malignant Penile Tumor 11
Carcinoma of Penis 11
Penile Ca 11
Ca Penis 11

Classifications:

MalaCards categories:
Global: Cancer diseases Rare diseases
Anatomical: Reproductive diseases Skin diseases
See all MalaCards categories (disease lists)
ICD10: 31
ICD11: 33


External Ids:

Disease Ontology 11 DOID:11615 DOID:3449
ICD9CM 34 187.3 187.4
MeSH 43 D010412
NCIt 49 C7547 C9061
ICD10 31 C60 C60.2 C60.9
UMLS 71 C0030849 C0153600 C0153601 more
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Summaries for Penile Cancer

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Disease Ontology: 11 A penile cancer that is located in the skin or tissues of the penis.

MalaCards based summary: Penile Cancer, also known as penis carcinoma, is related to penile benign neoplasm and phimosis. An important gene associated with Penile Cancer is CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), and among its related pathways/superpathways are Endometrial cancer and Malignant pleural mesothelioma. The drugs Irinotecan and Ipilimumab have been mentioned in the context of this disorder. Affiliated tissues include skin, lymph node and t cells, and related phenotypes are endocrine/exocrine gland and no phenotypic analysis

Wikipedia: 75 Penile cancer is cancer that develops in the skin or tissues of the penis. Symptoms may include abnormal... more...
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Related Diseases for Penile Cancer

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Diseases in the Penile Cancer family:

Penile Cancer, Adult

Diseases related to Penile Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 391)
# Related Disease Score Top Affiliating Genes
1 penile benign neoplasm 31.8 TP53 SLC8A1 SCN10A PIK3CA PDPN GP5
2 phimosis 31.3 TP53 PRR16 GP5 CDKN2A
3 human papillomavirus infectious disease 31.2 TP53 PIK3CA MIR31 GP5 EGFR CDKN2A
4 squamous cell carcinoma 30.9 TP53 PIK3CA PDPN EGFR CDKN2A
5 papilloma 30.8 UBE3A TP53 RASSF1 EGFR CDKN2A
6 penis basal cell carcinoma 30.5 GP6 GP5 CDKN2A
7 keratoacanthoma 30.4 TP53 PIK3CA EGFR
8 verrucous carcinoma 30.4 TP53 PIK3CA PDPN GP5 EGFR CDKN2A
9 anogenital venereal wart 30.2 UBE3A TP53 GP6 GP5 CDKN2A CD4
10 skin squamous cell carcinoma 30.1 TP53 EGFR CDKN2A
11 exanthem 30.1 EGFR CD4 CD274
12 leiomyosarcoma 30.0 TP53 CDKN2A CD274
13 apocrine adenocarcinoma 30.0 TP53 PIK3CA EGFR
14 suppressor of tumorigenicity 3 30.0 UBE3A TP53 CDKN2A
15 keratinizing squamous cell carcinoma 30.0 TP53 PIK3CA EGFR CDKN2A
16 carcinosarcoma 29.9 TP53 PIK3CA EGFR CDKN2A CD274
17 vulva cancer 29.9 TP53 PIK3CA GP5 EGFR CDKN2A CD274
18 small intestine cancer 29.8 TP53 PIK3CA EGFR CDKN2A CD274
19 cervix carcinoma 29.7 TP53 PIK3CA GP5 EGFR CDKN2A CD4
20 cervical cancer 29.6 UBE3A TP53 RASSF1 PIK3CA MIR31 CDKN2A
21 seminoma 29.6 TP53 RASSF1 PDPN
22 squamous cell carcinoma, head and neck 29.6 TP53 RASSF1 PIK3CA MIR31 EGFR CDKN2A
23 lymphangioma 29.6 TP53 PIK3CA PDPN EGFR CD4
24 cervical squamous cell carcinoma 29.6 TP53 RASSF1 PIK3CA EGFR CDKN2A
25 head and neck cancer 29.5 TP53 PIK3CA MIR31 EGFR CDKN2A CD4
26 skin carcinoma 29.5 TP53 MIR31 EGFR CDKN2A CD4 CD274
27 skin disease 29.5 TP53 PIK3CA MIR31 EGFR CDKN2A CD4
28 peripheral nervous system disease 29.4 TP53 SCN10A MIR31 EGFR CDKN2A CD4
29 oropharynx cancer 29.3 UBE3A TP53 PIK3CA GP5 EGFR CDKN2A
30 penile disease 29.0 TP53 SCN10A PDPN MIR31 GP5 EGFR
31 anus cancer 28.8 UBE3A TP53 PIK3CA GP6 GP5 EGFR
32 renal cell carcinoma, nonpapillary 28.8 TP53 RASSF1 PIK3CA PDPN MIR31 EGFR
33 malignant tumor of penis 11.5
34 penile cancer, adult 11.3
35 penis sarcoma 11.2
36 penis verrucous carcinoma 11.2
37 penis basaloid carcinoma 11.2
38 penis papillary carcinoma 11.2
39 penis squamous cell carcinoma 10.9
40 adenocarcinoma of the penis 10.5
41 rare tumor 10.4
42 lichen sclerosus et atrophicus 10.4
43 tonsillar pillar cancer 10.4 EGFR CDKN2A
44 b-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) 10.4 TP53 CDKN2A
45 endometrial squamous cell carcinoma 10.4 TP53 CDKN2A
46 cervical clear cell adenocarcinoma 10.4 GP5 CDKN2A
47 lymphocele 10.4
48 hereditary lymphedema i 10.3
49 squamous cell papilloma 10.3 TP53 GP5 CDKN2A
50 bizarre leiomyoma 10.3 TP53 CDKN2A

Graphical network of the top 20 diseases related to Penile Cancer:



Diseases related to Penile Cancer
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Symptoms & Phenotypes for Penile Cancer

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MGI Mouse Phenotypes related to Penile Cancer:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.9 CD4 CDKN2A CNDP2 EGFR HOXA3 MIR31
2 no phenotypic analysis MP:0003012 9.86 CD274 CD4 CDKN2A EGFR PIK3CA SCN10A
3 digestive/alimentary MP:0005381 9.61 CD4 CDKN2A EGFR HOXA3 PDPN PIK3CA
4 integument MP:0010771 9.4 CD274 CD4 CDKN2A CNDP2 EGFR GP6
Sources

Drugs & Therapeutics for Penile Cancer

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Drugs for Penile Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 70)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Irinotecan Approved, Investigational Phase 2 97682-44-5, 100286-90-6 60838
2
Ipilimumab Approved Phase 2 477202-00-9
3
Avelumab Approved, Investigational Phase 2 1537032-82-8
4
Carboplatin Approved Phase 2 41575-94-4 10339178 38904
5
Fluorouracil Approved Phase 2 51-21-8 3385
6
Niraparib Approved, Investigational Phase 2 1038915-60-4 24958200
7
Nivolumab Approved Phase 2 946414-94-4
8
Atezolizumab Approved, Investigational Phase 2 1380723-44-3
9
Vorinostat Approved, Investigational Phase 2 149647-78-9 5311
10
Pembrolizumab Approved Phase 2 1374853-91-4 254741536
11
Durvalumab Approved, Investigational Phase 2 1428935-60-7
12
Fludarabine Approved Phase 1, Phase 2 75607-67-9, 21679-14-1 30751 657237
13
Aldesleukin Approved Phase 1, Phase 2 110942-02-4
14
Cyclophosphamide Approved, Investigational Phase 1, Phase 2 50-18-0, 6055-19-2 2907
15
Docetaxel Approved, Investigational Phase 2 114977-28-5 148124
16
Isotretinoin Approved, Investigational, Nutraceutical Phase 2 302-79-4, 4759-48-2 5538 444795 5282379
17
Nimotuzumab Investigational Phase 2 780758-10-3
18
Entinostat Investigational Phase 1, Phase 2 209783-80-2 4261
19 topoisomerase I inhibitors Phase 2
20 interferons Phase 2
21 Interferon-alpha Phase 2
22 Interferon-alfa-1b Phase 2
23 Dermatologic Agents Phase 2
24 Cola Phase 1, Phase 2
25 Poly(ADP-ribose) Polymerase Inhibitors Phase 2
26 Immunoglobulins Phase 2
27 Immune Checkpoint Inhibitors Phase 2
28 Antibodies, Monoclonal Phase 2
29 Antibodies Phase 2
30 Immunologic Factors Phase 2
31 Histone Deacetylase Inhibitors Phase 2
32 Interleukin-12 Phase 2
33 Immunoglobulins, Intravenous Phase 2
34 Adjuvants, Immunologic Phase 2
35 Immunoglobulin G Phase 2
36 Angiogenesis Inhibitors Phase 2
37 Antiviral Agents Phase 1, Phase 2
38 Anti-Infective Agents Phase 1, Phase 2
39 Anti-Retroviral Agents Phase 1, Phase 2
40 Anti-HIV Agents Phase 1, Phase 2
41 Antimitotic Agents Phase 2
42 Tubulin Modulators Phase 2
43
Gemcitabine Approved Phase 1 95058-81-4, 122111-03-9 60750
44
Ganciclovir Approved, Investigational Phase 1 82410-32-0 3454
45 Antimetabolites Phase 1
46 Ganciclovir triphosphate Phase 1
47 Immunosuppressive Agents Phase 1
48 Alkylating Agents Phase 1
49 Antineoplastic Agents, Alkylating Phase 1
50 Antirheumatic Agents Phase 1

Interventional clinical trials:

(show top 50) (show all 55)
# Name Status NCT ID Phase Drugs
1 A Phase II Study of (Neoadjuvant Chemotherapy Trial Prior to Extirpative Surgery) for Clinical Stage TanyN2-3M0 Squamous Cell Carcinoma of the Penis Completed NCT00512096 Phase 2 Ifosfamide;Paclitaxel (Taxol);Cisplatin
2 A Phase I/II Study of T Cell Receptor Gene Therapy Targeting HPV-16 E6 for HPV-Associated Cancers Completed NCT02280811 Phase 1, Phase 2 Fludarabine;Cyclophosphamide;Aldesleukin
3 Phase II Study of Irinotecan (CPT 11) and Cisplatin (CDDP) in Metastatic or Locally Advanced Penile Carcinoma Completed NCT00066391 Phase 2 cisplatin;irinotecan hydrochloride
4 ALPHA INTERFERON AND CIS-RETINOIC ACID FOR THE TREATMENT OF SQUAMOUS CELL CARCINOMAS Completed NCT00002506 Phase 2 isotretinoin
5 A Single Center and Single Arm Study of TIP (Paclitaxel + Ifosfamide + Cisplatin) Combined With Nimotuzumab & Triprilimab as Neoadjuvant Treatment in Locally Advanced Penile Cancer Completed NCT04475016 Phase 2 Albumin-Bound Paclitaxel;Ifosfamide;Cisplatin;Nimotuzumab;Triprilimab
6 A Phase II Study of Lymphodepletion Followed by Autologous Tumor-Infiltrating Lymphocytes and High-Dose Aldesleukin for Human Papillomavirus-Associated Cancers Completed NCT01585428 Phase 2 Fludarabine;Cyclophosphamide;Aldesleukin
7 AMC-072: Protective Effect of Quadrivalent Vaccine in Young HIV-Positive Males Who Have Sex With Males Completed NCT01209325 Phase 2
8 A Phase II Trial of Vinflunine Chemotherapy in Locally-advanced and Metastatic Carcinoma of the Penis Completed NCT02057913 Phase 2 Vinflunine
9 Phase II Study of the Pan-HER Inhibitor Dacomitinib (PF-00299804) for Patients With Locally Advanced or Metastatic Squamous Cell Carcinoma of the Penis. Completed NCT01728233 Phase 2 Dacomitinib
10 A Phase II Trial of Cabazitaxel Chemotherapy in Relapsed Locally Advanced &/or Metastatic Carcinoma of the Penis Completed NCT03114254 Phase 2 Cabazitaxel
11 A Phase II Study of Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors Recruiting NCT03333616 Phase 2 Ipilimumab;Nivolumab
12 A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers Recruiting NCT04708470 Phase 1, Phase 2 Bintrafusp Alfa;NHS-IL12;Entinostat
13 A Phase II Study of Ipilimumab, Cabozantinib, and Nivolumab in Rare Genitourinary Cancers (ICONIC) Recruiting NCT03866382 Phase 2 Cabozantinib S-malate
14 Activity and Tolerability of Maintenance Avelumab Immunotherapy After First Line Polychemotherapy Including Platinum in Patients With Locally Advanced or Metastatic Squamous Cell Penile Carcinoma Recruiting NCT03774901 Phase 2 Avelumab
15 A Phase 2, Multi-centre, Open-label Study of Avelumab (MSB0010718C) in Locally Advanced or Metastatic Penile Cancer Patients Unfit for Platinum-based Chemotherapy or Progressed On or After Platinum-based Chemotherapy Recruiting NCT03391479 Phase 2 Avelumab
16 Prospective Phase II Study Evaluating a Multimodal Care of Inguinal Node Metastasis in Squamous Cell Carcinoma of the Penis by Bilateral Lymphadenectomy and Chemotherapy TIP Recruiting NCT02817958 Phase 2 Chemotherapy TIP
17 A Phase II Trial of Pembrolizumab Combined With Cisplatin-based Chemotherapy as First-line Systemic Therapy in Advanced Penile Cancer: LACOG 0218 HERCULES Trial Recruiting NCT04224740 Phase 2 Pembrolizumab;Standard of care therapy
18 A Phase 2 Study of the Combination Dostarlimab With Niraparib In Patients With Penile Carcinoma Who Have Progressed Following Chemotherapy Recruiting NCT05526989 Phase 2 Dostarlimab;Niraparib
19 A Single-arm, Open, Multicenter, Phase II Clinical Study of the Efficacy and Safety of Human Anti-PD-L1 Monoclonal Antibody Injection (LDP) in the Treatment of Urinary and Male Genital Tumors Recruiting NCT04718584 Phase 2 Human Anti-PD-L1 Monoclonal Antibody Injection (LDP)
20 Therapeutic HPV Vaccine Trial +/- Anti-CD40 in HPV-driven Squamous Cell Carcinoma Recruiting NCT03418480 Phase 1, Phase 2 BNT113
21 PERICLES (PEnile Cancer Radio- and Immunotherapy CLinical Exploration Study)-a Phase 2 Study of Atezolizumab With or Without Radiotherapy in Penile Cancer Active, not recruiting NCT03686332 Phase 2 Arm A: Atezolizumab and Radiotherapy;Arm B: Atezolizumab
22 Phase II Basket Trial Evaluating the Efficacy of a Combination of Pembrolizumab and Vorinostat in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma Active, not recruiting NCT04357873 Phase 2 pembrolizumab; vorinostat
23 A Multicenter, Open-Label, Single-Arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of INCMGA00012 in Advanced Penile Squamous Cell Carcinoma. Active, not recruiting NCT04231981 Phase 2 INCMGA0012
24 Phase II Study for the Evaluation of Efficacy of Pembrolizumab (MK-3475) in Patients With Rare Tumors Active, not recruiting NCT02721732 Phase 2
25 Phase II Trial of M7824 in Subjects With HPV Associated Malignancies Active, not recruiting NCT03427411 Phase 2 M7824
26 A Phase 2, Open-Label Study to Evaluate Efficacy of Combination Treatment With MEDI0457 (INO-3112) and Durvalumab (MEDI4736) in Patients With Recurrent/Metastatic Human Papilloma Virus Associated Cancers Active, not recruiting NCT03439085 Phase 2
27 Secured Access to Nivolumab for Adult Patients With Selected Rare Cancer Types Active, not recruiting NCT03012581 Phase 2 Nivolumab
28 A Feasibility Study of E7 TCR-T Cell Induction Therapy for Locoregionally Advanced HPV-Associated Cancers Not yet recruiting NCT05639972 Phase 1, Phase 2 Conditioning, E7 TCR-T cells, and aldesleukin
29 Phase II Study Of Weekly Docetaxel In Patients With Advanced Epidermoid Carcinoma Of The Penis Terminated NCT00058448 Phase 2 docetaxel
30 Phase II Study With Pazopanib and Weekly Paclitaxel in Metastatic or Locally Advanced Squamous Penile Carcinoma Patients Previously Treated With Cisplatin Based Chemotherapy Terminated NCT02279576 Phase 2 Pazopanib;Paclitaxel
31 A Randomized Phase II Study to Evaluate the Efficacy and Safety of Cetuximab in Metastatic Penile Carcinoma Withdrawn NCT02014831 Phase 2 Cetuximab;TIP
32 VACCINE THERAPY AND DETECTION OF IMMUNOLOGIC RESPONSES WITH HUMAN PAPILLOMAVIRUS 16 E6 AND E7 PEPTIDES IN PATIENTS WITH METASTATIC OR LOCALLY ADVANCED CERVICAL CANCER Completed NCT00019110 Phase 1
33 A Phase 1 Trial of the ATR Inhibitor BAY 1895344 in Combination With Cisplatin and With Cisplatin Plus Gemcitabine in Advanced Solid Tumors With an Emphasis on Urothelial Carcinoma Recruiting NCT04491942 Phase 1 Cisplatin;Elimusertib;Gemcitabine Hydrochloride
34 Evaluate the Safety and Immunogenicity of the 9-valent Human Papillomavirus Recombinant Vaccine (Hansenula Polymorpha) in Chinese Male Aged 9-45 Years: A Randomized, Blinded and Placebo-Controlled Phase I Study Recruiting NCT05518201 Phase 1
35 Fluorescent Guided Surgery in Penile Carcinoma Using Cetuximab-800IRDyeCW Recruiting NCT05376202 Phase 1 Cetuximab-IRDye800CW
36 A Phase 1 Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Select Advanced Solid Tumors Recruiting NCT04272034 Phase 1 INCB099318
37 An Open Multicenter Study of the Safety, Tolerability, and Pharmacokinetics of Different Doses of AntioncoRAN-M at Patients With Advanced-stage Solid Tumors With Cymeven® (Ganciclovir) Infusions Recruiting NCT05578820 Phase 1
38 A Phase 1 Study of Cabozantinib Plus Nivolumab (CaboNivo) Alone or in Combination With Ipilimumab (CaboNivoIpi) in Patients With Advanced/Metastatic Urothelial Carcinoma and Other Genitourinary Tumors Active, not recruiting NCT02496208 Phase 1 Cabozantinib S-malate
39 A Phase 1 Multiple-Dose Study to Evaluate the Safety and Tolerability of XmAb®22841 Monotherapy and in Combination With Pembrolizumab in Subjects With Selected Advanced Solid Tumors (DUET-4) Active, not recruiting NCT03849469 Phase 1
40 HPV-16/18 E6/E7-Specific T Lymphocytes in Patients With Relapsed HPV-Associated Cancers Active, not recruiting NCT02379520 Phase 1 Cytoxan;Fludarabine
41 Characterising Metastatic Penile Cancer Using Molecular Imaging - Hybrid MRI-PET [MRI-PET] Unknown status NCT02104063
42 Integrating a Health Information Technology System With a Web-based Mobile Health Educational Intervention to Support More Effective Provider-patient Communication and HPV Vaccine Utilization Completed NCT03346915
43 INtra-operative Evaluation of a Novel FLUorescENt C-mEt Tracer in Penile and Tongue Completed NCT04574427
44 A Message Framing Intervention for Increasing Parental Acceptance of Human Papillomavirus Vaccination Completed NCT03856437
45 Videoscopic Versus Open Inguinal Lymphadenectomy for Sentinel Node Positive Cutaneous Malignancies and Genitourinary Staging Procedures Completed NCT01526486
46 Monocentric Study of Validation of the Method "CaptHPV" for the Diagnosis of Human Papillomavirus Associated Infiltrating Carcinomas From a Biological Specimen. Completed NCT02981862
47 Risk of Cancer in Patients Exposed to Gabapentin in the GPRD Completed NCT01236053 Gabapentin prescriptions
48 Videoendoscopic Radical Inguinal Lymphadenectomy Versus Open Radical Inguinal Lymphadenectomy in Patients With Penile Cancer: a Feasibility Randomised Controlled Trial Recruiting NCT05592639
49 Development of Diagnostics and Treatment of Urological Cancers Recruiting NCT02994758
50 Integrated Cancer Repository for Cancer Research Recruiting NCT02012699

Search NIH Clinical Center for Penile Cancer

Cochrane evidence based reviews: penile neoplasms

Sources

Genetic Tests for Penile Cancer

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Anatomical Context for Penile Cancer

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Organs/tissues related to Penile Cancer:

FMA: Skin
MalaCards : Skin, Lymph Node, T Cells, Tongue, Colon, Liver, Cervix
Sources

Publications for Penile Cancer

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Articles related to Penile Cancer:

(show top 50) (show all 2460)
# Title Authors PMID Year
1
The Evolving Landscape of Viral, Immune, and Molecular Biomarkers in Penile Cancer. 62
36424078 2023
2
Recent developments in the diagnosis and management of N1 penile cancer. 62
36444651 2023
3
Buried Penis Reconstruction in the Management of Localized Penile Cancer. 62
36206827 2022
4
Diagnostic Accuracy of Dynamic Sentinel Lymph Node Biopsy for Penile Cancer: A Systematic Review and Meta-analysis. 62
36470729 2022
5
A giant inguinal lymph-node metastasis of penile cancer: A case report. 62
35768305 2022
6
Clinicopathological characteristics of carcinoma penis over 10 years in a tertiary-level oncology center in Nepal: a retrospective study of 380 cases. 62
36454449 2022
7
[Solitary ulcer of unknown etiology on the glans penis]. 62
36447060 2022
8
Increased prevalence of human papillomavirus in fresh tissue from penile cancers compared to non-malignant penile samples: a case-control study. 62
36443686 2022
9
French AFU Cancer Committee Guidelines - Update 2022-2024: penile cancer. 62
36400476 2022
10
Will Dynamic Sentinel Lymph Node Biopsy Surpass Inguinal Lymph Node Dissection in High-risk Node-negative Penile Cancer? 62
36336613 2022
11
Commentary on: "Novel strategy using a spiral embedded flap for meatal stenosis after post-penile cancer amputation surgery: a single-center experience". 62
35708356 2022
12
Patient-Reported Outcomes in Penile Cancer Patients: Quality of Life, Sexual and Urinary Function. What do we Know? 62
36037936 2022
13
Novel strategy using a spiral embedded flap for meatal stenosis after post-penile cancer amputation surgery: a single-center experience. 62
35435337 2022
14
Optimizing Target Volume for Adjuvant Radiotherapy in Penile Cancer. 62
36460183 2022
15
"Light green up": Indocyanine Green Fluorescence Imaging-guided Robotic Bilateral Inguinal Lymphadenectomy by the Hypogastric Subcutaneous Approach for Penile Cancer. 62
36120419 2022
16
Combination of radiation and immunotherapy in the treatment of genitourinary malignancies: A systematic review and meta-analysis. 62
36372634 2022
17
WHO 2022 classification of penile and scrotal cancers: updates and evolution. 62
36221864 2022
18
Sintilimab-Induced Diabetic Ketoacidosis in a Patient with Radiation and Multichemorefractory Penile Cancer: A Case Report and Literature Review. 62
36354692 2022
19
Distal urethral carcinoma: Contemporary management with phallus preserving techniques. 62
35012866 2022
20
Updates in the use of radiotherapy in the management of primary and locally-advanced penile cancer. 62
36381600 2022
21
Bilateral inguinal lymphadenectomy using simultaneous double laparoscopies for penile cancer: A retrospective study. 62
35781183 2022
22
What would one of the greatest natural scientists and educators of the eighteenth century, Georg Christoph Lichtenberg, say about the current therapy management of patients with penile cancer? 62
35727370 2022
23
Morbidity and risk factors for complications of inguinal lymph node dissection in penile cancer. 62
36208315 2022
24
Penile cancer: Updates in systemic therapy. 62
36381603 2022
25
A comprehensive analysis of penile cancer in the region with the highest worldwide incidence reveals new insights into the disease. 62
36243680 2022
26
Penile cancer with bilateral inguinal lymph node metastases survives more than 4 years: A case report. 62
36307266 2022
27
Sentinel Node Identification with Hybrid Tracer-guided and Conventional Dynamic Sentinel Node Biopsy in Penile Cancer: A Prospective Study in 130 Patients from the Two National Referral Centres in Sweden. 62
36272960 2022
28
Disparities in Healthcare Access, Education, and Geographical Factors That Affect Surgical Outcomes in Penile Cancer. 62
36238422 2022
29
The Predictive Significance of Prognostic Nutritional Index and Serum Albumin/Globulin Ratio on the Overall Survival of Penile Cancer Patients Undergoing Penectomy. 62
36290873 2022
30
Phalloplasty following penectomy for penile cancer. 62
36381591 2022
31
Incidence and risk factor analysis of complications after sentinel node biopsy for penile cancer. 62
35257463 2022
32
HPV infection and 5mC/5hmC epigenetic markers in penile squamous cell carcinoma: new insights into prognostics. 62
36284309 2022
33
Mohs microsurgery for localized penile carcinoma: 10 year retrospective review of local recurrence rates and surgical complications. 62
36088244 2022
34
Human papillomavirus in men. 62
36257902 2022
35
Advances in penile-sparing surgical approaches. 62
36381598 2022
36
The dual pathogenesis of penile neoplasia: The heterogeneous morphology of human papillomavirus-related tumors. 62
36381592 2022
37
The Relationships Between Social Media and Human Papillomavirus Awareness and Knowledge: Cross-sectional Study. 62
36125858 2022
38
High diagnostic accuracy of inguinal ultrasonography and fine-needle aspiration followed by dynamic sentinel lymph node biopsy in men with impalpable and palpable inguinal lymph nodes. 62
35098622 2022
39
The Lack of a Physical Exam During New Patient Telehealth Visits Does Not Impact Plans for Office and Operating Room Procedures. 62
35772487 2022
40
Lymphovascular and perineural invasion are risk factors for inguinal lymph node metastases in men with T1G2 penile cancer. 62
35411405 2022
41
PD-1 inhibitor treatment in a penile cancer patient with MMR/MSI status heterogeneity: A case report. 62
36162043 2022
42
Prognostic value of neutrophil-to-lymphocyte ratio (NLR) in penile cancer: A systematic review and meta-analysis. 62
36147188 2022
43
FDG PET/CT in a Patient With Syphilis Suspected of Having Penile Cancer. 62
35930717 2022
44
Quality of life, voiding and sexual function of penile cancer patients: DaPeCa-10-a cross-sectional questionnaire survey. 62
35950041 2022
45
Prediction of survival in patients with penile cancer after lymph node dissection. 62
35165027 2022
46
Glansectomy and Reconstruction for Penile Cancer: A Systematic Review. 62
34903488 2022
47
Patient reported outcomes in advanced penile cancer. 62
35662500 2022
48
[Knowledge of German-speaking urologists regarding the association between penile cancer and human papilloma virus: results of a survey of the European PROspective Penile Cancer Study (E-PROPS)]. 62
31745963 2022
49
Ecologic Analysis of Correlates of Cervical Cancer Morbidity and Mortality in Sub-Saharan Africa. 62
35700009 2022
50
[Pilonidal sinus of the penis]. 62
36036704 2022
Sources

Variations for Penile Cancer

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Expression for Penile Cancer

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Search GEO for disease gene expression data for Penile Cancer.
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Pathways for Penile Cancer

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Pathways related to Penile Cancer according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Endometrial cancer 74
Show member pathways
 12.42 TP53 RASSF1 PIK3CA EGFR CDKN2A
2
Malignant pleural mesothelioma 74
12.24 TP53 RASSF1 PIK3CA EGFR CDKN2A CD274
3
T-cell activation SARS-CoV-2 74
Show member pathways
 11.8 TP53 PIK3CA CDKN2A CD4
4
DNA IR-double strand breaks and cellular response via ATM 74
Show member pathways
 11.66 TP53 RASSF1 CDKN2A
5
Microglia pathogen phagocytosis pathway 74
Show member pathways
 11.51 PIK3CA PDPN GP6
6
Prader-Willi and Angelman syndrome 74
11.39 UBE3A TP53 CDKN2A
7
p53 pathway 61
11.24 TP53 RASSF1 CDKN2A
8
Head and neck squamous cell carcinoma 74
11.12 TP53 PIK3CA EGFR CDKN2A
9
G-protein signaling_K-RAS regulation pathway 22
10.86 RASSF1 PIK3CA EGFR
10
Bladder cancer 74
10.53 TP53 RASSF1 EGFR CDKN2A
11
Relationship between inflammation, COX-2 and EGFR 74
10.48 PIK3CA EGFR
Sources

GO Terms for Penile Cancer

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Biological processes related to Penile Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme-linked receptor protein signaling pathway GO:0007167 9.26 GP6 CD4
2 positive regulation of miRNA maturation GO:1903800 8.62 TP53 EGFR
Sources

Sources for Penile Cancer

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2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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