MCID: PRN017
MIFTS: 28

Perianal Hematoma

Categories: Blood diseases, Cardiovascular diseases, Gastrointestinal diseases, Skin diseases

Aliases & Classifications for Perianal Hematoma

MalaCards integrated aliases for Perianal Hematoma:

Name: Perianal Hematoma 12 15
External Thrombosed Haemorrhoids 12 32
Thrombosed External Hemorrhoids 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9745
ICD9CM 34 455.4
SNOMED-CT 67 26373009
ICD10 32 I84.3 K64.5
UMLS 71 C0155784

Summaries for Perianal Hematoma

MalaCards based summary : Perianal Hematoma, also known as external thrombosed haemorrhoids, is related to constipation and neurofibrosarcoma. An important gene associated with Perianal Hematoma is APOLD1 (Apolipoprotein L Domain Containing 1), and among its related pathways/superpathways are Peptide ligand-binding receptors and Endothelin Pathways. Affiliated tissues include lymph node and skin.

Wikipedia : 74 Perianal hematoma is a hematoma located in, or on the border of the anus. It is sometimes... more...

Related Diseases for Perianal Hematoma

Diseases related to Perianal Hematoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 constipation 29.5 TAC1 NPY CALCA APOLD1
2 neurofibrosarcoma 10.2 NF1 MXD3
3 leukemia, acute myeloid 10.1
4 leukemia, acute lymphoblastic 10.1
5 myelodysplastic syndrome 10.1
6 prostatic hypertrophy 10.1
7 sarcoma 10.1
8 spindle cell sarcoma 10.1
9 myeloid sarcoma 10.1
10 pancreatic somatostatinoma 10.1 NF1 CALCA
11 somatostatinoma 10.1 NF1 CALCA
12 giant cell reparative granuloma 10.0 NF1 CALCA
13 thrombosis 10.0
14 hemorrhoid 10.0
15 leprosy 2 10.0 NPY CALCA
16 autonomic nervous system benign neoplasm 10.0 NF1 CALCA
17 carcinoid syndrome 10.0 NPY CALCA
18 peripheral nervous system benign neoplasm 10.0 NF1 CALCA
19 multiple endocrine neoplasia, type iib 10.0 NF1 CALCA
20 aortic aneurysm 9.9
21 internal hemorrhoid 9.9
22 detrusor sphincter dyssynergia 9.9 TAC1 CALCA
23 interval angle-closure glaucoma 9.9 TAC1 KNG1
24 bursitis 9.8 TAC1 KNG1
25 renovascular hypertension 9.8 NF1 KNG1
26 burning mouth syndrome 9.7 TAC1 CALCA
27 neurodermatitis 9.7 TAC1 NPS
28 aids phobia 9.6 TAC1 NPS
29 multiple endocrine neoplasia, type iia 9.6 NF1 CALCA
30 cystitis 9.6 TAC1 KNG1 ADRA1D
31 complex regional pain syndrome 9.6 TAC1 NPY CALCA
32 dental pulp disease 9.6 TAC1 NPS
33 parasitic ectoparasitic infectious disease 9.4 TAC1 NPS
34 hirschsprung disease 1 9.4 TAC1 NPY CALCA APOLD1
35 pheochromocytoma 9.3 NPY NF1 KNG1 CALCA
36 carbamazepine allergy 9.3 TAC1 NPS CALCA
37 causalgia 9.3 TAC1 NPS CALCA
38 epicondylitis 9.3 TAC1 NPS CALCA
39 algoneurodystrophy 9.3 TAC1 NPS CALCA
40 trigeminal nerve disease 9.3 TAC1 NPS CALCA
41 polyradiculopathy 9.3 TAC1 NPS CALCA
42 trigeminal neuralgia 9.3 TAC1 NPS CALCA
43 specific developmental disorder 9.3 TAC1 NPY NPS
44 migraine with aura 9.3 TAC1 NPS CALCA
45 disease of mental health 9.2 TAC1 NPY NPS
46 anxiety 9.0 TAC1 NPY NPS
47 reflex sympathetic dystrophy 9.0 TAC1 NPY NPS CALCA
48 autonomic nervous system disease 9.0 TAC1 NPY NPS CALCA
49 myofascial pain syndrome 8.9 TAC1 NPS KNG1 CALCA
50 paine syndrome 8.9 TAC1 NPS KNG1 CALCA

Graphical network of the top 20 diseases related to Perianal Hematoma:



Diseases related to Perianal Hematoma

Symptoms & Phenotypes for Perianal Hematoma

Drugs & Therapeutics for Perianal Hematoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prevention and/or Reduction of Hemorrhoids and/or Thrombosed External Hemorrhoids (TEH) Using the HEM-AVERT Perianal Stabilizer Instrument Completed NCT00487045 Phase 1
2 Treatment of Thrombosed External Hemorrhoids: Comparison of the Thrombectomy and Local Excision Procedures in Terms of Results and Outcome: A Multi-Centre, International, Prospective Cohort Study Not yet recruiting NCT03903536

Search NIH Clinical Center for Perianal Hematoma

Genetic Tests for Perianal Hematoma

Anatomical Context for Perianal Hematoma

MalaCards organs/tissues related to Perianal Hematoma:

40
Lymph Node, Skin

Publications for Perianal Hematoma

Articles related to Perianal Hematoma:

(show all 14)
# Title Authors PMID Year
1
Use of Ultrasonography in Clarifying the Etiology of Anal Pain. 61
30065494 2017
2
Conventional (CH) vs. stapled hemorrhoidectomy (SH) in surgical treatment of hemorrhoids. Ten years experience. 61
22462333 2012
3
Core out fistulectomy, anal sphincter reconstruction and primary repair of internal opening in the treatment of complex anal fistula. 61
19459524 2009
4
[Trans-anal disarterization of internal hemorrhoids under Doppler control with mucopexy and lifting in treatment of stage III-IV hemorrhoids]. 61
19365337 2009
5
Transanal repair of rectocele and full rectal mucosectomy with one circular stapler: a novel surgical technique. 61
15868504 2005
6
Anal fistula: Levovist-enhanced endoanal ultrasound: a pilot study. 61
12626915 2003
7
[Proctologic day-surgery. Results of 2000 surgical interventions]. 61
11396071 2001
8
[Hemorrhoidal thrombosis and perianal hematoma: diagnosis and treatment]. 61
8712590 1995
9
[Perianal hematoma--spontaneous thrombosis of the perianal region-- early surgical treatment]. 61
2618484 1989
10
Perianal thrombosis. 61
3366042 1988
11
Perianal hematoma--a sign of leakage after rupture of aortic aneurysm. 61
5764454 1969
12
[PERIANAL HEMATOMA AND PERIANAL SPONTANEOUS THROMBOSIS]. 61
14316242 1964
13
[EXTERNAL HEMORRHOIDS. DIFFERENTIAL DIAGNOSIS OF PERI-ANAL THROMBOSIS AND PERIANAL HEMATOMA AND THEIR TREATMENT]. 61
14243625 1964
14
[Perianal hematoma]. 61
14391194 1955

Variations for Perianal Hematoma

Expression for Perianal Hematoma

Search GEO for disease gene expression data for Perianal Hematoma.

Pathways for Perianal Hematoma

GO Terms for Perianal Hematoma

Cellular components related to Perianal Hematoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell GO:0005623 9.02 TAC1 NPY KNG1 CALCA ADRA1D

Biological processes related to Perianal Hematoma according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.8 TAC1 NPY NPS KNG1 CALCA ADRA1D
2 cell-cell signaling GO:0007267 9.69 TAC1 CALCA ADRA1D
3 visual learning GO:0008542 9.52 NPS NF1
4 cellular response to nerve growth factor stimulus GO:1990090 9.49 TAC1 CALCA
5 feeding behavior GO:0007631 9.48 NPY CALCA
6 negative regulation of osteoclast differentiation GO:0045671 9.46 NF1 CALCA
7 vasodilation GO:0042311 9.43 KNG1 CALCA
8 regulation of blood pressure GO:0008217 9.43 TAC1 NPY CALCA
9 response to pain GO:0048265 9.4 TAC1 CALCA
10 positive regulation of synaptic transmission, GABAergic GO:0032230 9.37 TAC1 NPS
11 positive regulation of cytosolic calcium ion concentration GO:0007204 9.26 TAC1 KNG1 CALCA ADRA1D
12 positive regulation of action potential GO:0045760 9.16 TAC1 NPS
13 neuropeptide signaling pathway GO:0007218 8.92 TAC1 NPY NPS CALCA

Sources for Perianal Hematoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....