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MCID: PRR001
MIFTS: 34

Periarthritis

Categories: Bone diseases
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Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Periarthritis

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MalaCards integrated aliases for Periarthritis:

Name: Periarthritis 11 43 14 16 71

Classifications:

MalaCards categories:
Anatomical: Bone diseases
See all MalaCards categories (disease lists)
ICD10: 31


External Ids:

Disease Ontology 11 DOID:2964
MeSH 43 D010489
SNOMED-CT 68 50921008
ICD10 31 M77.9
UMLS 71 C0031037
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Summaries for Periarthritis

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MalaCards based summary: Periarthritis is related to frozen shoulder and chondrocalcinosis. An important gene associated with Periarthritis is NT5E (5'-Nucleotidase Ecto), and among its related pathways/superpathways are Ebstein-Barr virus LMP1 signaling and FGF23 signaling in hypophosphatemic rickets and related disorders. The drugs Triamcinolone and Loxoprofen have been mentioned in the context of this disorder. Affiliated tissues include bone, lymph node and spinal cord.
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Related Diseases for Periarthritis

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Diseases related to Periarthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 125)
# Related Disease Score Top Affiliating Genes
1 frozen shoulder 31.5 TNF TAC1 HFM1
2 chondrocalcinosis 31.4 PTH ALPL
3 tendinitis 30.6 TNF TAC1
4 hypophosphatasia, adult 30.0 PTH PHOSPHO1 ALPL
5 hypophosphatasia 30.0 PTH PHOSPHO1 ALPL
6 tenosynovitis 29.9 TNF AGBL2
7 bursitis 29.9 TNF TAC1 PTH HFM1 ALPL
8 calcification of joints and arteries 29.7 SLC20A1 NT5E ALPL
9 spondylosis 29.7 TNF TAC1 PTH
10 sarcoidosis 1 29.4 TNF TAC1 PTH
11 epicondylitis 10.4
12 osteochondrosis 10.3
13 hypophosphatasia, childhood 10.2 PHOSPHO1 ALPL
14 graves disease 1 10.2
15 gout 10.2
16 calciphylaxis 10.2 PTH NT5E
17 calcific tendinitis 10.1
18 hyperthyroidism 10.1
19 osteoarthritis 10.1
20 arterial calcification of infancy 10.1 PHOSPHO1 NT5E ALPL
21 anal fistula 10.1 TNF NT5E
22 dupuytren contracture 10.1
23 spondylolisthesis 10.1 TAC1 PTH
24 arachnoiditis 10.1 TNF TAC1
25 nerve compression syndrome 10.1 TAC1 PTH
26 lagophthalmos 10.1 TNF TAC1
27 irritant dermatitis 10.0 TNF TAC1
28 mononeuropathy 10.0 TNF TAC1
29 taeniasis 10.0 TNF TAC1
30 trichomoniasis 10.0 TNF CCL20
31 synovitis 10.0
32 pulmonary tuberculosis 10.0
33 arthropathy 10.0
34 septic arthritis 10.0
35 hypophosphatemic rickets, x-linked dominant 10.0 PTH ALPL
36 interstitial cystitis 10.0 TNF TAC1
37 burning mouth syndrome 10.0 TNF TAC1
38 complex regional pain syndrome 10.0 TNF TAC1
39 brittle bone disorder 10.0 PTH NT5E ALPL
40 aspiration pneumonia 10.0 TNF TAC1
41 ankylosis 10.0 TNF PHOSPHO1 ALPL
42 corneal ulcer 10.0 TNF TAC1
43 lactose intolerance 10.0 TNF PTH
44 vaginal disease 10.0 TNF CCL20
45 dental pulp disease 10.0 TNF TAC1 NT5E
46 cryptosporidiosis 9.9 TNF TAC1
47 systemic lupus erythematosus 9.9
48 spondylosis, cervical 9.9
49 myocardial infarction 9.9
50 peyronie's disease 9.9

Graphical network of the top 20 diseases related to Periarthritis:



Diseases related to Periarthritis
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Symptoms & Phenotypes for Periarthritis

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Drugs & Therapeutics for Periarthritis

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Drugs for Periarthritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 33)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 3 124-94-7 31307
2
Loxoprofen Approved Phase 3 80382-23-6, 68767-14-6 3965
3
Methocarbamol Approved, Vet_approved Phase 3 532-03-6 4107
4
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
5
Betamethasone Approved, Vet_approved Phase 3 378-44-9 9782
6
Cortisone Experimental Phase 3 53-06-5 222786
7 Immunologic Factors Phase 3
8 Hormones Phase 3
9 Hormone Antagonists Phase 3
10
Triamcinolone hexacetonide Phase 3
11
Triamcinolone diacetate Phase 3
12
Triamcinolone Acetonide Phase 3 6436
13 glucocorticoids Phase 3
14 Immunosuppressive Agents Phase 3
15 Analgesics Phase 3
16 Antirheumatic Agents Phase 3
17 Anti-Inflammatory Agents, Non-Steroidal Phase 3
18 Analgesics, Non-Narcotic Phase 3
19 Anti-Inflammatory Agents Phase 3
20 Anti-Arrhythmia Agents Phase 3
21 Sodium Channel Blockers Phase 3
22 Anesthetics, Local Phase 3
23 Pharmaceutical Solutions Phase 3
24 Anesthetics Phase 3
25 Diuretics, Potassium Sparing Phase 3
26
Hyaluronic acid Approved, Vet_approved 9004-61-9 53477741
27
Meloxicam Approved, Vet_approved 71125-38-7 54677470 5281106
28
Etodolac Approved, Investigational, Vet_approved 41340-25-4 3308
29 Adjuvants, Immunologic
30 Viscosupplements
31 Protective Agents
32 Cyclooxygenase Inhibitors
33 Cyclooxygenase 2 Inhibitors

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Outcome in Shoulder Capsulitis (Frozen Shoulder) Between Corticosteroid and Corticosteroid With Distension Compared to Wait and See Policy, a Randomised Controlled Trial Unknown status NCT01570985 Phase 3 Triamcinolone Acetonide
2 Open-label, Single-group, Multicentre, Phase III Study to Confirm the Efficacy and Safety of IP-TN When Administered for 2 Weeks to Patients With Low Back Pain, Scapulohumeral Periarthritis, or Cervico-omo-brachial Syndrome Associated With Muscle Strain Completed NCT02831569 Phase 3 Loxoprofen sodium;Methocarbamol
3 Evaluation of the Effectiveness of ARTHRO -Distension Plus Intensive Mobilisation in Shoulder Capsulitis Completed NCT00724113 Phase 3
4 A Randomised Double Blind Controlled Trial of Injection of Local Anaesthetic and Corticosteroid Under Ultrasound Control in the Greater Trochanteric Pain Syndrome. Terminated NCT01807962 Phase 3 rapidocain and bethametsaone;sterile saline
5 A Validation Study of Sodium Hyaluronate in Patients With Periarthritis of Shoulder Unknown status NCT03365388 Sodium Hyaluronate;Aerzhi
6 Safety and Efficacy of Meloxicam (MOBIC) Compared to Other NSAIDs in Approved Therapeutic Dosages and Routes of Administration in an Observational Cohort Study of Patients With Rheumatoid Arthritis, Osteoarthritis, Lumbago, Scapulohumeral Periarthritis, Neck, Shoulder and Arm Syndrome Completed NCT02180516 Meloxicam;Other Non Steroidal Anti-Inflammatory Drugs (NSAIDs) except etodolac
7 Extracorporeal Shock Wave Treatment - Can the Pain be Reduced? Completed NCT01429883

Search NIH Clinical Center for Periarthritis

Cochrane evidence based reviews: periarthritis

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Genetic Tests for Periarthritis

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Anatomical Context for Periarthritis

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Organs/tissues related to Periarthritis:

MalaCards : Bone, Lymph Node, Spinal Cord, Skin, Lung, Thyroid, Breast
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Publications for Periarthritis

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Articles related to Periarthritis:

(show top 50) (show all 968)
# Title Authors PMID Year
1
Diagnostic Approach to Patients with Low Serum Alkaline Phosphatase. 62
36348061 2022
2
Selective Suprascapular and Axillary nerve (SSAX) block - A diaphragm sparing regional anesthetic technique for shoulder surgeries: A case series. 62
36337404 2022
3
Comparison of the Efficacy of Platelet-Rich Plasma (PRP) and Local Corticosteroid Injection in Periarthritis Shoulder: A Prospective, Randomized, Open, Blinded End-Point (PROBE) Study. 62
36262947 2022
4
Prognostic factors determining long-term outcomes of conservative treatment for acute calcific periarthritis of the hand. 62
35715307 2022
5
[Exploration of the development direction of contemporary acupuncture-moxibustion school: acupuncture-moxibustion treatment for periarthritis of shoulder]. 62
35938340 2022
6
Acute calcific periarthritis-a commonly misdiagnosed pathology. 62
35149896 2022
7
Long-term outcome of patients with palindromic rheumatism treated with methotrexate. 62
35133068 2022
8
[Connotation of Baimai disease and analysis of compatibility and usage of Baimai Ointment: based on Tibetan medicine theory]. 62
35343170 2022
9
A retrospective study of ultrasound-guided intervention for frozen shoulder in the frozen stage. 62
36329976 2022
10
Retrospective study of therapeutic effect of Tongbi paste vs Fufangzhuifeng paste for shoulder periarthritis. 62
35099438 2022
11
Multifocal calcific periarthritis with distinctive clinical and radiological features in patients with CD73 deficiency. 62
33744914 2021
12
First Report of Two Cases of Löfgren's Syndrome after SARS-CoV-2 Vaccination-Coincidence or Causality? 62
34835244 2021
13
Scapular stabilization exercise based on the type of scapular dyskinesis versus traditional rehabilitation training in the treatment of periarthritis of the shoulder: study protocol for a randomized controlled trial. 62
34663424 2021
14
An atypical distribution of acute calcific periarthritis in the setting of trauma. 62
33547764 2021
15
Acute calcific periarthritis of the hip joint. 62
34664372 2021
16
Observation on the clinical effect of shoulder manipulative release combined with individualized treatment of scapulohumeral periarthritis under brachial plexus anesthesia. 62
34542943 2021
17
Calcific Periarthritis in a Patient With Previous Cushing Disease Treated With Transsphenoidal Surgery. 62
31977649 2021
18
Effect of low dose methotrexate as an add-on therapy in patients with palindromic rheumatism unresponsive to hydroxychloroquine: An observational study. 62
34101572 2021
19
Role of Radiographs and Ultrasound in Diagnosing Calcific Tendinitis and Periarthritis in the Wrist and Hand with Ultrasound-Guided Barbotage as Management Tool. 62
34790305 2021
20
[Progress of researches in acupotomy visualization under ultrasound]. 62
34190463 2021
21
[Acute calcific periarthritis - a differential diagnosis of pyoarthrosis of the hand]. 62
33465786 2021
22
Comparison of efficacy and safety of complementary and alternative therapies for scapulohumeral periarthritis: A protocol for Bayesian network meta-analysis. 62
33950966 2021
23
Uses, chemical compositions, pharmacological activities and toxicology of Clematidis Radix et Rhizome- a Review. 62
33476714 2021
24
Effect of Remote and Local Acupuncture Points on Periarthritis of Shoulder: A Comparative Study. 62
35770597 2021
25
Effects of heat-sensitive moxibustion combined with naprapathy and warming needle moxibustion combined with naprapathy in patients with periarthritis of shoulder. 62
34377257 2021
26
A Review of Aceclofenac: Analgesic and Anti-Inflammatory Effects on Musculoskeletal Disorders. 62
34876850 2021
27
Type A aortic dissection developed after type B dissection with the presentation of shoulder pain: A case report. 62
33511190 2021
28
[Herbal cake separated moxibustion combined with umbrella shaped acupuncture with round sharp needle for chronic scapulohumeral periarthritis of cold-damp stagnation]. 62
33415870 2020
29
Acute calcific periarthritis secondary to calcium hydroxyapatite crystal deposition in the wrist: a case report. 62
33408854 2020
30
Different acupuncture therapies combined with rehabilitation in the treatment of scapulohumeral periarthritis: A protocol for systematic review and network meta-analysis. 62
33371060 2020
31
Efficacy and safety of warm needle treatment for scapulohumeral periarthritis: A protocol for systematic review and meta-analysis. 62
33217841 2020
32
High-Potential surface on zirconia ceramics for bacteriostasis and biocompatibility. 62
32416519 2020
33
Acupuncture and moxibustion therapy for scapulohumeral periarthritis: Protocol for an overview of systematic reviews and meta-analysis. 62
32871872 2020
34
MRI findings in calcific deposits in and around shoulder: atypical locations beyond supraspinatus. 62
32131976 2020
35
[Treatment of scapulohumeral periarthritis by "metal hook fishing"-like needling technique combined with Tuina manipulation]. 62
32869579 2020
36
Acute calcific periarthritis of the proximal phalangeal joint on the fifth finger: A case report and literature review. 62
32756172 2020
37
[Back arm flexion and extension combined with manipulation for the treatment of patient with adhesive scapulohumeral periarthritis]. 62
32700492 2020
38
Evidence Base of Clinical Studies on Qi Gong: A Bibliometric Analysis. 62
32444061 2020
39
The evaluation of gene polymorphisms associated with autoinflammatory syndrome in patients with palindromic rheumatism complicated by intermittent hydrarthrosis. 62
31897954 2020
40
Tuina for periarthritis of shoulder: A systematic review protocol. 62
32176055 2020
41
Dual-energy computed-tomography-based discrimination between basic calcium phosphate and calcium pyrophosphate crystal deposition in vivo. 62
32636945 2020
42
Identification of constituents in Gui-Zhi-Jia-Ge-Gen-Tang by LC-IT-MS combined with LC-Q-TOF-MS and elucidation of their metabolic networks in rat plasma after oral administration. 62
31831128 2019
43
Acute calcific periarthritis in proximal interphalangeal joint: An unusual cause of acute finger pain. 62
29029953 2019
44
Acute Calcific Periarthritis of the Hand: A Case Report in an Active Duty Soldier. 62
30938808 2019
45
Basic Calcium Phosphate Crystal Periarthritis Involving the Distal Interphalangeal Joints in a Patient with Systemic Lupus Erythematosus. 62
31366882 2019
46
[Treatment of scapulohumeral periarthritis by Fuyang-pot warming combined with electroacupuncture stimulation]. 62
31475497 2019
47
Representative survey of frozen shoulder questionnaire responses from the Japan Shoulder Society: What are the appropriate diagnostic terms for primary idiopathic frozen shoulder, stiff shoulder or frozen shoulder? 62
30638969 2019
48
[Exploration of dominant diseases and clinical application characteristics of wrist-ankle acupuncture therapy based on data mining technology]. 62
31190508 2019
49
Clinical applications of ear reconstruction with Medpor. 62
31303621 2019
50
No vascular calcification on cardiac computed tomography spanning asfotase alfa treatment for an elderly woman with hypophosphatasia. 62
30825650 2019
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Variations for Periarthritis

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Expression for Periarthritis

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Search GEO for disease gene expression data for Periarthritis.
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Pathways for Periarthritis

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Pathways related to Periarthritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Ebstein-Barr virus LMP1 signaling 74
10.52 TNF CCL20
3
Mammary gland development pathway - Embryonic development (Stage 1 of 4) 74
9.88 TNF ALPL
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GO Terms for Periarthritis

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Cellular components related to Periarthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular membrane-bounded organelle GO:0065010 8.8 PHOSPHO1 ALPL

Biological processes related to Periarthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 bone mineralization GO:0030282 9.73 PTH PHOSPHO1 ALPL
2 response to vitamin D GO:0033280 9.71 PTH ALPL
3 phosphate ion homeostasis GO:0055062 9.67 PTH ALPL
4 negative regulation of heart rate GO:0010459 9.62 TNF PLN
5 response to macrophage colony-stimulating factor GO:0036005 9.26 TNF ALPL
6 obsolete biomineralization GO:0110148 9.16 NT5E ALPL
7 calcium ion homeostasis GO:0055074 9.02 PTH NT5E ALPL

Molecular functions related to Periarthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pyrophosphatase activity GO:0016462 9.26 PHOSPHO1 ALPL
2 phosphoethanolamine phosphatase activity GO:0052732 8.92 PHOSPHO1 ALPL
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Sources for Periarthritis

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2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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