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MCID: PRR001
MIFTS: 33

Periarthritis

Categories: Bone diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Periarthritis

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MalaCards integrated aliases for Periarthritis:

Name: Periarthritis 12 44 15 17 70

Classifications:

MalaCards categories:
Anatomical: Bone diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:2964
MeSH 44 D010489
SNOMED-CT 67 50921008
ICD10 32 M77.9
UMLS 70 C0031037
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Summaries for Periarthritis

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MalaCards based summary : Periarthritis is related to bursitis and enthesopathy. An important gene associated with Periarthritis is PHOSPHO1 (Phosphoethanolamine/Phosphocholine Phosphatase 1), and among its related pathways/superpathways is Endochondral Ossification. The drugs Triamcinolone and Methocarbamol have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and lymph node, and related phenotype is immune system.

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Related Diseases for Periarthritis

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Diseases related to Periarthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 85)
# Related Disease Score Top Affiliating Genes
1 bursitis 30.4 TAC1 PHOSPHO1 ALPL
2 enthesopathy 30.0 MEFV ENPP1 ANKH
3 arthropathy 29.8 B2M ANKH ALPL
4 hypophosphatasia 29.6 PHOSPHO1 ENPP1 ANKH ALPL
5 chondrocalcinosis 29.4 MEFV ENPP1 ANKH ALPL
6 carpal tunnel syndrome 29.4 TAC1 B2M
7 osteomalacia 29.3 ENPP1 ALPL
8 frozen shoulder 10.4
9 epicondylitis 10.4
10 tendinitis 10.3
11 osteochondrosis 10.3
12 gout 10.2
13 hyperthyroidism 10.1
14 calcific tendinitis 10.1
15 tenosynovitis 10.1
16 hypercementosis 10.1 PHOSPHO1 ENPP1
17 graves disease 1 10.0
18 plica syndrome 10.0
19 synovitis 10.0
20 pulmonary tuberculosis 10.0
21 osteoarthritis 10.0
22 facial neuralgia 10.0 TAC1 SCYL3
23 akinetopsia 10.0 TAC1 B2M
24 nerve compression syndrome 10.0 TAC1 B2M
25 chronic recurrent multifocal osteomyelitis 10.0 MEFV ALPL
26 amyloidosis aa 9.9 MEFV B2M
27 hypophosphatasia, childhood 9.9 PHOSPHO1 ENPP1 ALPL
28 spondylosis, cervical 9.9
29 crest syndrome 9.9
30 spondylosis 9.9
31 systemic scleroderma 9.9
32 septic arthritis 9.9
33 arthritis 9.9
34 herpes zoster 9.9
35 periostitis 9.9
36 hypophosphatasia, infantile 9.9 PHOSPHO1 ENPP1 ALPL
37 ankylosis 9.9 PHOSPHO1 ENPP1 ANKH
38 craniometaphyseal dysplasia, autosomal dominant 9.9 ENPP1 ANKH ALPL
39 mineral metabolism disease 9.9 ENPP1 B2M
40 pseudoxanthoma elasticum 9.9 ENPP1 ANKH ALPL
41 bone disease 9.9 B2M ANKH ALPL
42 meningoencephalitis 9.9 TAC1 B2M
43 craniosynostosis 9.8 ENPP1 ANKH ALPL
44 hypophosphatasia, adult 9.8 PHOSPHO1 ENPP1 ANKH ALPL
45 pfeiffer syndrome 9.8
46 hypercholesterolemia, familial, 1 9.8
47 hypertriglyceridemia, familial 9.8
48 systemic lupus erythematosus 9.8
49 rheumatoid arthritis 9.8
50 sarcoidosis 1 9.8

Graphical network of the top 20 diseases related to Periarthritis:



Diseases related to Periarthritis
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Symptoms & Phenotypes for Periarthritis

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MGI Mouse Phenotypes related to Periarthritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.23 AGBL2 ALPL ANKH B2M ENPP1 MEFV
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Drugs & Therapeutics for Periarthritis

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Drugs for Periarthritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 33)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 3 124-94-7 31307
2
Methocarbamol Approved, Vet_approved Phase 3 532-03-6 4107
3
Loxoprofen Approved Phase 3 68767-14-6, 80382-23-6 3965
4
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
5
Betamethasone Approved, Vet_approved Phase 3 378-44-9 9782
6
Cortisone Experimental Phase 3 53-06-5 222786
7 Immunologic Factors Phase 3
8 glucocorticoids Phase 3
9 Hormone Antagonists Phase 3
10 Triamcinolone diacetate Phase 3
11 Triamcinolone hexacetonide Phase 3
12 Hormones Phase 3
13 Immunosuppressive Agents Phase 3
14 triamcinolone acetonide Phase 3
15 Analgesics, Non-Narcotic Phase 3
16 Analgesics Phase 3
17 Antirheumatic Agents Phase 3
18 Anti-Inflammatory Agents Phase 3
19 Anti-Inflammatory Agents, Non-Steroidal Phase 3
20 Pharmaceutical Solutions Phase 3
21 Anti-Arrhythmia Agents Phase 3
22 Anesthetics Phase 3
23 Sodium Channel Blockers Phase 3
24 Anesthetics, Local Phase 3
25 Diuretics, Potassium Sparing Phase 3
26
Hyaluronic acid Approved, Vet_approved 9004-61-9 53477741
27
Meloxicam Approved, Vet_approved 71125-38-7 5281106 54677470
28
Etodolac Approved, Investigational, Vet_approved 41340-25-4 3308
29 Protective Agents
30 Viscosupplements
31 Adjuvants, Immunologic
32 Cyclooxygenase 2 Inhibitors
33 Cyclooxygenase Inhibitors

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Outcome in Shoulder Capsulitis (Frozen Shoulder) Between Corticosteroid and Corticosteroid With Distension Compared to Wait and See Policy, a Randomised Controlled Trial Unknown status NCT01570985 Phase 3 Triamcinolone Acetonide;Triamcinolone Acetonide
2 Open-label, Single-group, Multicentre, Phase III Study to Confirm the Efficacy and Safety of IP-TN When Administered for 2 Weeks to Patients With Low Back Pain, Scapulohumeral Periarthritis, or Cervico-omo-brachial Syndrome Associated With Muscle Strain Completed NCT02831569 Phase 3 Loxoprofen sodium;Methocarbamol
3 Evaluation of the Effectiveness of ARTHRO -Distension Plus Intensive Mobilisation in Shoulder Capsulitis Completed NCT00724113 Phase 3
4 A Randomised Double Blind Controlled Trial of Injection of Local Anaesthetic and Corticosteroid Under Ultrasound Control in the Greater Trochanteric Pain Syndrome. Terminated NCT01807962 Phase 3 rapidocain and bethametsaone;sterile saline
5 A Validation Study of Sodium Hyaluronate in Patients With Periarthritis of Shoulder Unknown status NCT03365388 Sodium Hyaluronate;Aerzhi
6 Safety and Efficacy of Meloxicam (MOBIC) Compared to Other NSAIDs in Approved Therapeutic Dosages and Routes of Administration in an Observational Cohort Study of Patients With Rheumatoid Arthritis, Osteoarthritis, Lumbago, Scapulohumeral Periarthritis, Neck, Shoulder and Arm Syndrome Completed NCT02180516 Meloxicam;Other Non Steroidal Anti-Inflammatory Drugs (NSAIDs) except etodolac
7 Extracorporeal Shock Wave Treatment - Can the Pain be Reduced? Completed NCT01429883

Search NIH Clinical Center for Periarthritis

Cochrane evidence based reviews: periarthritis

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Genetic Tests for Periarthritis

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Anatomical Context for Periarthritis

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MalaCards organs/tissues related to Periarthritis:

40
Bone, Skin, Lymph Node, Spinal Cord, Kidney, Thyroid, Breast
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Publications for Periarthritis

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Articles related to Periarthritis:

(show top 50) (show all 947)
# Title Authors PMID Year
1
Uses, chemical compositions, pharmacological activities and toxicology of Clematidis Radix et Rhizome- a Review. 61
33476714 2021
2
Multifocal Calcific Periarthritis with Distinctive Clinical and Radiological Features in Patients with CD73 Deficiency. 61
33744914 2021
3
An atypical distribution of acute calcific periarthritis in the setting of trauma. 61
33547764 2021
4
[Acute calcific periarthritis - a differential diagnosis of pyoarthrosis of the hand]. 61
33465786 2021
5
Type A aortic dissection developed after type B dissection with the presentation of shoulder pain: A case report. 61
33511190 2021
6
Different acupuncture therapies combined with rehabilitation in the treatment of scapulohumeral periarthritis: A protocol for systematic review and network meta-analysis. 61
33371060 2020
7
Acute calcific periarthritis secondary to calcium hydroxyapatite crystal deposition in the wrist: a case report. 61
33408854 2020
8
[Herbal cake separated moxibustion combined with umbrella shaped acupuncture with round sharp needle for chronic scapulohumeral periarthritis of cold-damp stagnation]. 61
33415870 2020
9
Efficacy and safety of warm needle treatment for scapulohumeral periarthritis: A protocol for systematic review and meta-analysis. 61
33217841 2020
10
High-Potential surface on zirconia ceramics for bacteriostasis and biocompatibility. 61
32416519 2020
11
Acupuncture and moxibustion therapy for scapulohumeral periarthritis: Protocol for an overview of systematic reviews and meta-analysis. 61
32871872 2020
12
[Treatment of scapulohumeral periarthritis by "metal hook fishing"-like needling technique combined with Tuina manipulation]. 61
32869579 2020
13
MRI findings in calcific deposits in and around shoulder: atypical locations beyond supraspinatus. 61
32131976 2020
14
Acute calcific periarthritis of the proximal phalangeal joint on the fifth finger: A case report and literature review. 61
32756172 2020
15
[Back arm flexion and extension combined with manipulation for the treatment of patient with adhesive scapulohumeral periarthritis]. 61
32700492 2020
16
Evidence Base of Clinical Studies on Qi Gong: A Bibliometric Analysis. 61
32444061 2020
17
The evaluation of gene polymorphisms associated with autoinflammatory syndrome in patients with palindromic rheumatism complicated by intermittent hydrarthrosis. 61
31897954 2020
18
Tuina for periarthritis of shoulder: A systematic review protocol. 61
32176055 2020
19
Calcific Periarthritis in a Patient With Previous Cushing Disease Treated With Transsphenoidal Surgery. 61
31977649 2020
20
Dual-energy computed-tomography-based discrimination between basic calcium phosphate and calcium pyrophosphate crystal deposition in vivo. 61
32636945 2020
21
Identification of constituents in Gui-Zhi-Jia-Ge-Gen-Tang by LC-IT-MS combined with LC-Q-TOF-MS and elucidation of their metabolic networks in rat plasma after oral administration. 61
31831128 2019
22
Acute calcific periarthritis in proximal interphalangeal joint: An unusual cause of acute finger pain. 61
29029953 2019
23
Acute Calcific Periarthritis of the Hand: A Case Report in an Active Duty Soldier. 61
30938808 2019
24
[Treatment of scapulohumeral periarthritis by Fuyang-pot warming combined with electroacupuncture stimulation]. 61
31475497 2019
25
Basic Calcium Phosphate Crystal Periarthritis Involving the Distal Interphalangeal Joints in a Patient with Systemic Lupus Erythematosus. 61
31366882 2019
26
Representative survey of frozen shoulder questionnaire responses from the Japan Shoulder Society: What are the appropriate diagnostic terms for primary idiopathic frozen shoulder, stiff shoulder or frozen shoulder? 61
30638969 2019
27
[Exploration of dominant diseases and clinical application characteristics of wrist-ankle acupuncture therapy based on data mining technology]. 61
31190508 2019
28
Clinical applications of ear reconstruction with Medpor. 61
31303621 2019
29
Effectiveness and safety of fire needle on periarthritis of shoulder: Protocol for a systematic review and meta-analysis. 61
31096502 2019
30
No vascular calcification on cardiac computed tomography spanning asfotase alfa treatment for an elderly woman with hypophosphatasia. 61
30825650 2019
31
Fibromyalgia diagnostic model derived from combination of American College of Rheumatology 1990 and 2011 criteria. 61
31091511 2019
32
Apatite calcific periarthritis of the radial collateral ligament of the thumb: a case report and review of the literature. 61
31595220 2019
33
[Clinical observation of warm acupuncture combined with yoga posture method in the treatment of periarthritis with frozen period]. 61
30672253 2019
34
Effective period of conservative treatment in patients with acute calcific periarthritis of the hand. 61
30428905 2018
35
Periarticular calcification mimicking inflammatory polyarthritis in chronic kidney disease. 61
30588988 2018
36
Osteoid osteoma of the scaphoid bone associated with flexor carpi radialis calcific tendinitis and treated with CT-guided RF ablation. 61
29541786 2018
37
[Acupuncture from Tiaokou (ST 38) to Chengshan (BL 57) combined with local exercise for periarthritis]. 61
30141290 2018
38
Botany, traditional use, phytochemistry, pharmacology, quality control, and authentication of Radix Gentianae Macrophyllae-A traditional medicine: A review. 61
30097114 2018
39
[Percutaneous dynamic release in stress position by acupotomy in treating severe scapulohumeral periarthritis]. 61
29890806 2018
40
Progression of palindromic rheumatism to juvenile idiopathic arthritis in a Japanese girl carrying heterozygous L110P-E148Q substitutions of MEFV gene. 61
26457478 2018
41
Basic calcium phosphate crystal-associated musculoskeletal syndromes: an update. 61
29227355 2018
42
Toxicokinetics of strychnine and brucine after the oral administration of Biqi capsule to rats by RRLC-MS/MS. 61
29027676 2018
43
Acute calcific periarthritis of the thumb: Correlated sonographic and radiographic findings. 61
29552260 2018
44
Arnica compositum, Hekla lava and Acidum Nitricum Together are Superior to Arnica compositum Alone in the Local Treatment of Symptomatic Calcific Periarthritis of the Shoulder: A Pilot Study. 61
29557754 2018
45
Arthroscopic treatment of symptomatic calcific periarthritis on the medial side of the knee after posterior cruciate ligament reconstruction: Case report and literature review. 61
28479128 2017
46
Large malignant granular cell tumor with suprascapular nerve and brachial plexus invasion: A case report and literature review. 61
29095317 2017
47
[Explanation on Evidence-based Guidelines of Clinical Practice with Acupuncture and Moxibustion: Periarthritis of Shoulder]. 61
29354922 2017
48
High-Velocity Paint Gun Injuries. 61
28654465 2017
49
The effect of intra-articular hyaluronate and tramadol injection on patients with adhesive capsulitis of the shoulder. 61
28453454 2017
50
[Clinical Research on Double-needle Winding and Pulling Combined with Electroacupuncture Therapy in Treating Scapulohumeral Periarthritis]. 61
29071987 2017
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Variations for Periarthritis

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Expression for Periarthritis

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Search GEO for disease gene expression data for Periarthritis.
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Pathways for Periarthritis

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Pathways related to Periarthritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Endochondral Ossification 1
10.44 ENPP1 ALPL
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GO Terms for Periarthritis

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Cellular components related to Periarthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular membrane-bounded organelle GO:0065010 8.62 PHOSPHO1 ALPL

Biological processes related to Periarthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endochondral ossification GO:0001958 9.4 PHOSPHO1 ALPL
2 phosphate-containing compound metabolic process GO:0006796 9.37 SLC20A1 ENPP1
3 phosphate ion transmembrane transport GO:0035435 9.32 SLC20A1 ANKH
4 phosphate ion transport GO:0006817 9.26 SLC20A1 ANKH
5 inorganic diphosphate transport GO:0030505 9.16 ENPP1 ANKH
6 biomineral tissue development GO:0031214 9.13 SLC20A1 ENPP1 ALPL
7 regulation of bone mineralization GO:0030500 8.8 PHOSPHO1 ENPP1 ANKH

Molecular functions related to Periarthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pyrophosphatase activity GO:0016462 8.96 PHOSPHO1 ALPL
2 inorganic phosphate transmembrane transporter activity GO:0005315 8.62 SLC20A1 ANKH
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Sources for Periarthritis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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