MCID: PRC012
MIFTS: 53

Pericardial Effusion

Categories: Cardiovascular diseases

Aliases & Classifications for Pericardial Effusion

MalaCards integrated aliases for Pericardial Effusion:

Name: Pericardial Effusion 12 29 55 6 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:118
MeSH 44 D010490
NCIt 50 C3319
SNOMED-CT 68 373945007 70370001
ICD10 33 I31.3
UMLS 73 C0031039

Summaries for Pericardial Effusion

Disease Ontology : 12 A pericardium disease that is characterized by an abnormal accumulation of fluid in the pericardial cavity.

MalaCards based summary : Pericardial Effusion is related to cardiac tamponade and constrictive pericarditis. An important gene associated with Pericardial Effusion is ADA (Adenosine Deaminase), and among its related pathways/superpathways are Kaposi's sarcoma-associated herpesvirus infection and MicroRNAs in cardiomyocyte hypertrophy. The drugs Rivaroxaban and Colchicine have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and kidney, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 76 Pericardial effusion (\"fluid around the heart\") is an abnormal accumulation of fluid in the... more...

Related Diseases for Pericardial Effusion

Diseases in the Pericardial Effusion family:

Pericardial Effusion, Chronic

Diseases related to Pericardial Effusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 349)
# Related Disease Score Top Affiliating Genes
1 cardiac tamponade 32.2 NPPB REN TNFRSF1A
2 constrictive pericarditis 31.1 ADA NPPB
3 inferior myocardial infarction 30.4 NPPB PIK3C2A
4 pneumonia 30.2 CRP IL6 PIK3C2A
5 castleman disease 30.1 CRP IL6
6 endocarditis 30.1 CRP IL6 PIK3C2A
7 peritonitis 29.9 ADA CRP IL6 MUC16
8 kawasaki disease 29.9 CRP IL6 NPPB
9 meningitis 29.8 ADA CRP IL6 NLRP3
10 apnea, obstructive sleep 29.8 CRP IL6 REN
11 cardiac rupture 29.7 CHKB CRP
12 familial mediterranean fever 29.6 CRP NLRP3 TNFRSF1A
13 pericarditis 29.5 ADA CRP IL6 NPPB TNFRSF1A
14 kidney disease 29.2 CRP NPPA NPPB REN
15 sleep apnea 28.8 CRP IL6 NPPB REN VEGFA
16 tetralogy of fallot 28.7 CRP NPPA NPPB REN VEGFA
17 chronic kidney failure 28.4 CRP IL6 NPPA NPPB REN
18 acute myocardial infarction 28.3 CHKB CRP NPPA NPPB PIK3C2A
19 pulmonary hypertension 28.1 HIF1A IL6 NPPA NPPB REN VEGFA
20 heart disease 27.8 CRP IL6 NPPA NPPB PIK3C2A REN
21 dilated cardiomyopathy 27.8 CHKB CRP IL6 NPPA NPPB REN
22 myocardial infarction 26.3 CHKB CRP HIF1A IL6 NPPA NPPB
23 pericardial effusion, chronic 12.3
24 hemopericardium 12.2
25 cantu syndrome 11.4
26 lymphedema, hereditary, iii 11.3
27 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 11.1
28 dressler's syndrome 11.1
29 pericardial tuberculosis 11.1
30 familial cold autoinflammatory syndrome 2 10.8 CRP NLRP3
31 abdominal tuberculosis 10.7 ADA CRP
32 miliary tuberculosis 10.7 ADA MUC16
33 chronic meningitis 10.7 CRP NLRP3
34 metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 10.7 ACADVL PIK3C2A
35 vibrio vulnificus infection 10.6 IL6 PIK3C2A
36 chronic angina 10.6 NPPB REN
37 cold agglutinin disease 10.6 CRP IL6
38 chronic thromboembolic pulmonary hypertension 10.6 CRP NPPB
39 acute adrenal insufficiency 10.6 IL6 REN
40 acute cholangitis 10.6 CRP IL6
41 intravascular papillary endothelial hyperplasia 10.5 HIF1A VEGFA
42 tuberculous peritonitis 10.5 ADA CRP MUC16
43 neutrophilia, hereditary 10.5 CRP IL6
44 pleurisy 10.5 ADA CRP MUC16
45 hypoaldosteronism 10.5 NPPA REN
46 postural hypotension 10.5 NPPA REN
47 renal artery disease 10.5 NPPA REN
48 uremic pruritus 10.4 CRP IL6
49 hypertension, diastolic 10.4 NPPA REN
50 conjunctivitis 10.4 IL6 MUC16 NLRP3

Graphical network of the top 20 diseases related to Pericardial Effusion:



Diseases related to Pericardial Effusion

Symptoms & Phenotypes for Pericardial Effusion

MGI Mouse Phenotypes related to Pericardial Effusion:

46 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.25 NLRP3 NPPA PIK3C2A REN TNFRSF1A VEGFA
2 cardiovascular system MP:0005385 10.24 ACADVL ADA CRP FGF2 HIF1A IL6
3 behavior/neurological MP:0005386 10.16 ACADVL CHKB FGF2 HIF1A IL6 PIK3C2A
4 hematopoietic system MP:0005397 10.16 ADA FGF2 HIF1A IL6 NLRP3 NPPA
5 cellular MP:0005384 10.13 ACADVL ADA FGF2 HIF1A IL6 NLRP3
6 immune system MP:0005387 10.06 ADA CRP HIF1A IL6 NLRP3 PIK3C2A
7 muscle MP:0005369 10.02 TNFRSF1A VEGFA ACADVL ADA CHKB FGF2
8 liver/biliary system MP:0005370 9.91 ACADVL ADA HIF1A IL6 NLRP3 TNFRSF1A
9 nervous system MP:0003631 9.81 FGF2 HIF1A IL6 NLRP3 PIK3C2A REN
10 neoplasm MP:0002006 9.73 ACADVL FGF2 HIF1A IL6 TNFRSF1A VEGFA
11 renal/urinary system MP:0005367 9.61 ADA HIF1A IL6 NLRP3 NPPA PIK3C2A
12 skeleton MP:0005390 9.23 NLRP3 TNFRSF1A VEGFA ADA CHKB FGF2

Drugs & Therapeutics for Pericardial Effusion

Drugs for Pericardial Effusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 210)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Rivaroxaban Approved Phase 4,Phase 3 366789-02-8
2
Colchicine Approved Phase 4,Phase 3 64-86-8 6167 2833
3
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
4
Everolimus Approved Phase 4 159351-69-6 6442177
5
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
6
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
7
Mycophenolic acid Approved Phase 4 24280-93-1 446541
8
Sirolimus Approved, Investigational Phase 4 53123-88-9 5284616 6436030 46835353
9
Amiodarone Approved, Investigational Phase 4,Not Applicable 1951-25-3 2157
10
Acetaminophen Approved Phase 4 103-90-2 1983
11
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
12
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
13
gamma-Aminobutyric acid Approved, Investigational Phase 4 56-12-2 119
14
Ibuprofen Approved Phase 4 15687-27-1 3672
15
Morphine Approved, Investigational Phase 4 57-27-2 5288826
16
Menthol Approved Phase 4,Not Applicable 2216-51-5 16666
17
Serine Approved, Nutraceutical Phase 4,Phase 3 56-45-1 5951
18
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
19 Kava Approved, Investigational, Nutraceutical Phase 4,Not Applicable 9000-38-8
20 Anticoagulants Phase 4,Phase 2,Phase 3
21 Antithrombin III Phase 4,Phase 3
22 Antithrombins Phase 4,Phase 3
23 Factor Xa Inhibitors Phase 4,Phase 3
24 HIV Protease Inhibitors Phase 4,Phase 3
25
protease inhibitors Phase 4,Phase 3
26 Serine Proteinase Inhibitors Phase 4,Phase 3
27 Antirheumatic Agents Phase 4,Phase 3,Phase 2
28 Antimitotic Agents Phase 4,Phase 3,Phase 2,Phase 1
29 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
30 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Phase 1
31 Analgesics Phase 4,Phase 3
32 Analgesics, Non-Narcotic Phase 4
33 Anti-Inflammatory Agents Phase 4,Phase 3
34 Anti-Inflammatory Agents, Non-Steroidal Phase 4
35 Cyclooxygenase Inhibitors Phase 4
36 Peripheral Nervous System Agents Phase 4,Phase 3,Not Applicable
37 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Phase 2
38 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 1,Phase 2
39 Antifungal Agents Phase 4
40 Antitubercular Agents Phase 4
41 Cyclosporins Phase 4
42 Anti-Arrhythmia Agents Phase 4,Phase 3,Not Applicable
43 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Not Applicable
44 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Not Applicable
45 Cytochrome P-450 CYP2D6 Inhibitors Phase 4,Not Applicable
46 Cytochrome P-450 CYP3A Inhibitors Phase 4,Not Applicable
47 Cytochrome P-450 Enzyme Inhibitors Phase 4,Not Applicable
48 Diuretics, Potassium Sparing Phase 4,Not Applicable
49 Potassium Channel Blockers Phase 4,Not Applicable
50 Sodium Channel Blockers Phase 4,Not Applicable

Interventional clinical trials:

(show top 50) (show all 165)
# Name Status NCT ID Phase Drugs
1 The Effect of Chest Tubes Using Active Clearance Technology® on the Incidence of Postoperative Atrial Fibrillation Unknown status NCT02808897 Phase 4
2 SmartTouch Catheter for Left Anterior Line - SmarT Line Study Unknown status NCT02217657 Phase 4
3 Safety and Feasibility of Arrhythmia Ablation Using the Amigo Remote Robotic System as Compared With Manual Ablation Unknown status NCT01834872 Phase 4
4 Evaluation of WATCHMAN Left Atrial Appendage Occlusion Device in Patients With Atrial Fibrillation Versus Rivaroxaban Unknown status NCT02549963 Phase 4 Rivaroxaban
5 Non Steroidal Anti Inflammatory Treatment for Post Operative Pericardial Effusion Completed NCT00247052 Phase 4 diclofenac;diclofenac;matching placebo
6 Cochicine Treatment for Post- Operative Pericardial Effusion Completed NCT01266694 Phase 4 Colchicines;Placebo
7 Everolimus in de Novo Heart Transplant Recipients Completed NCT01017029 Phase 4 Everolimus;Mycophenolate mofetil + Everolimus
8 Prevention of Atrial Fibrillation Following Esophagectomy Completed NCT00420017 Phase 4 Amiodarone
9 Catheter Evaluation for Endocardial Ablation in Patients With Typical Atrial Flutter Completed NCT00318565 Phase 4
10 Study Evaluating the Effiacy of a 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) in Adults Completed NCT00744263 Phase 4
11 Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac Surgery Completed NCT01966172 Phase 4 Ibuprofen;Gabapentin;Morphine;Paracetamol
12 Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension Completed NCT01642407 Phase 4 Sildenafil
13 Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion Recruiting NCT02260206 Phase 4 Colchicine
14 Left Atrial Appendage Closure vs. Novel Anticoagulation Agents in Atrial Fibrillation Recruiting NCT02426944 Phase 4 NOAC
15 Heterotopic Implantation Of the Edwards-Sapien Transcatheter Aortic Valve in the Inferior VEna Cava for the Treatment of Severe Tricuspid Regurgitation (HOVER) Recruiting NCT02339974 Phase 4
16 NAVISTAR® THERMOCOOL® Catheter Post Approval Registry Active, not recruiting NCT00964392 Phase 4
17 Safety, Tolerability, Pharmacokinetics and Efficacy of Two Different Rates of Subcutanous Remodulin® Dose Titration in Pulmonary Arterial Hypertension Withdrawn NCT02893995 Phase 4 Slow Dose Titration Group of Subcutaneous Treprostinil;Rapid Dose Titration Group of Subcutaneous Treprostinil
18 COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation (COPPS-2 Trial) Unknown status NCT01552187 Phase 3 Colchicine;Placebo
19 ELIGIBLE (Efficacy of Left atrIal Appendage Closure After GastroIntestinal BLEeding) Unknown status NCT01628068 Phase 3
20 Trial of Drainage With or Without Bleomycin Instillation for Malignant Pericardial Effusion Completed NCT00132613 Phase 3 Pericardial instillation of bleomycin after drainage
21 A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis Completed NCT00810849 Phase 3 Prednisolone
22 WATCHMAN Left Atrial Appendage System for Embolic PROTECTion in Patients With Atrial Fibrillation Completed NCT00129545 Phase 2, Phase 3 Warfarin
23 THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation Completed NCT01385202 Phase 3
24 NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation Completed NCT00116428 Phase 3 Antiarrhythmic drug
25 THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation CONTINUED ACCESS Completed NCT01639495 Phase 3
26 Strategy of Continued Versus Interrupted Novel Oral Anti-coagulant at Time of Device Surgery in Patients With Moderate to High Risk of Arterial Thromboembolic Events Completed NCT01675076 Phase 3 Dabigatran;Rivaroxaban;Apixaban
27 Scleroderma: Cyclophosphamide or Transplantation (SCOT) Completed NCT00114530 Phase 2, Phase 3 cyclophosphamide
28 Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer Completed NCT00347412 Phase 3 Paclitaxel and Carboplatin;NOV-002 Injection in combination with Carboplatin vs. Paclitaxel and Carboplatin
29 A Study of Abciximab and Reteplase When Administered Prior to Catherization After a Myocardial Infarction (Finesse) Completed NCT00046228 Phase 3 abciximab placebo; reteplase placebo, abciximab, abciximab;Abciximab; reteplase; abciximab placebo; abciximab;abciximab; reteplase placebo; abciximab placebo; abciximab;abciximab placebo; reteplase placebo, abciximab, abciximab;abciximab; reteplase placebo; abciximab placebo; abciximab;Abciximab; reteplase; abciximab placebo; abciximab
30 Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate Cancer Completed NCT00744497 Phase 3 Placebo;Dasatinib;Docetaxel;Prednisone
31 An Extension of Study Fx-005 Evaluating Long-Term Safety And Clinical Outcomes Of Fx-1006A In Patients With Transthyretin Amyloid Polyneuropathy Completed NCT00791492 Phase 2, Phase 3 Fx-1006A
32 IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion Recruiting NCT02673879 Phase 3
33 WAVECREST Post Market Clinical Follow-Up (PMCF) Study Recruiting NCT03204695 Phase 3
34 Dasatinib Holiday for Improved Tolerability Recruiting NCT02890784 Phase 3 dasatinib (SPRYCEL®)
35 International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia Recruiting NCT02724163 Phase 3 Gemtuzumab ozogamicin;Liposomal daunorubicin;Mitoxantrone;Fludarabine;Cytarabine;Busulfan;Cyclophosphamide
36 Colchicine in Postoperative Fontan Patients Not yet recruiting NCT03575572 Phase 2, Phase 3 Colchicine
37 NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation- Treatment Use Study Terminated NCT00721149 Phase 3
38 NGR-hTNF in Combination With Standard Chemotherapy to Treat Patients With Advanced Non-small Cell Lung Cancer Unknown status NCT00994097 Phase 2 NGR-hTNF;Cisplatin;Gemcitabine;Pemetrexed
39 Ablation of Paroxysmal Atrial Fibrillation Using the Appropriate Contact Force in a Chinese Population Unknown status NCT02493075 Phase 1, Phase 2
40 ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment Unknown status NCT00005645 Phase 2 ILX-295501
41 Combined CABG and Stem-Cell Transplantation for Heart Failure Unknown status NCT00418418 Phase 2
42 Phase I/II Safety Study of IPI-504 in Relapsed/Refractory Stage IIIb, or Stage IV Non-small Cell Lung Cancer (NSCLC) Completed NCT00431015 Phase 1, Phase 2 IPI-504
43 Dasatinib (Sprycel™) in Patients With Newly Diagnosed Core Binding Factor (CBF) Acute Myeloid Leukemia (AML) Completed NCT00850382 Phase 1, Phase 2 Dasatinib;daunorubicin;Cytarabine
44 A Study of Bevacizumab Plus Carboplatin and Paclitaxel in Subjects With Advanced, Previously Untreated, Squamous Non-Small Cell Lung Cancer (BRIDGE) Completed NCT00318136 Phase 2 Bevacizumab;Carboplatin;Paclitaxel
45 Triplet Combination First Line Treatment in Non Small Cell Lung Cancer (NSCLC) Completed NCT00942825 Phase 2 CBP501 + Cisplatin + Pemetrexed;Cisplatin + Pemetrexed
46 Phase II Study of Cetuximab in Combination With Carboplatin and Docetaxel for Patients With Advanced Non-Small Cell Lung Cancer Completed NCT00251498 Phase 2 Cetuximab
47 Safety and Efficacy Evaluation of Two Year Imatinib Treatment in Adjuvant Gastrointestinal Stromal Tumor (GIST) Completed NCT01172548 Phase 2 imatinib mesylate
48 Sunitinib in Treating Patients With Brain Metastases Caused by Kidney Cancer or Melanoma Completed NCT00462982 Phase 2 sunitinib malate
49 Safety and Efficacy of Autologous Endothelial Progenitor Cell CD 133 for Therapeutic Angiogenesis Completed NCT00694642 Phase 1, Phase 2
50 A Pilot Study to Evaluate the Safety and Efficacy of the Apica Access, Stabilization and Closure (ASC™) Device Completed NCT01721642 Phase 1, Phase 2

Search NIH Clinical Center for Pericardial Effusion

Genetic Tests for Pericardial Effusion

Genetic tests related to Pericardial Effusion:

# Genetic test Affiliating Genes
1 Pericardial Effusion 29

Anatomical Context for Pericardial Effusion

MalaCards organs/tissues related to Pericardial Effusion:

41
Lung, Heart, Kidney, Endothelial, Myeloid, Prostate, Thyroid

Publications for Pericardial Effusion

Articles related to Pericardial Effusion:

(show top 50) (show all 783)
# Title Authors Year
1
Incidence of pericardial effusion after left atrial appendage closure: The impact of underlying heart rhythm-Data from the EWOLUTION study. ( 29722469 )
2018
2
Possible involvement of IL-6-producing tissue-resident macrophages in early-onset pericardial effusion pathogenesis after hematopoietic stem cell transplantation. ( 29384263 )
2018
3
A Case Series of Two Patients Presenting With Pericardial Effusion as First Manifestation of Non-Small Cell Lung Cancer With <i>BRAF</i> Mutation and Expression Of PD-L1. ( 29760834 )
2018
4
Reply to the letter: &amp;quot;Pericardial effusion in community-acquired pneumonia: casuality or etiology?&amp;quot; ( 29735269 )
2018
5
Pericardial effusion following cardiac surgery. A single-center experience. ( 29171276 )
2018
6
Massive pleural and pericardial effusion due to hypothyroidism in a patient with a surgically treated thyroid-stimulating hormone-producing pituitary adenoma. ( 29757110 )
2018
7
Conservative management of nivolumab-induced pericardial effusion: a case report and review of literature. ( 29761026 )
2018
8
Relevant pericardial effusion caused by cytomegalovirus infection in an immunocompetent patient: a case report. ( 29347961 )
2018
9
Pericardial Effusion in Obstructive Sleep Apnea without Pulmonary Arterial Hypertension and Daily Hypoxemia - is it Unusual? ( 29808980 )
2018
10
Idiopathic Loculated and Septated Pericardial Effusion. ( 29871831 )
2018
11
Recurrent Pericardial Effusion While Receiving Nivolumab for Metastatic Lung Adenocarcinoma: Case Report and Review of the Literature. ( 29937384 )
2018
12
Pleural and pericardial effusion in a long-term PD patient - a defying diagnosisa8c. ( 29231161 )
2018
13
Morphology quiz: Pericardial effusion as first manifestation of malignancy. ( 29732625 )
2018
14
Idiosyncratic Pericardial Effusion Associated With Minoxidil. ( 29746289 )
2018
15
Left Atrial Appendage Perforation Does Not Always Mean Pericardial Effusion. ( 29880108 )
2018
16
PCR evaluation of selected vector-borne pathogens in dogs with pericardial effusion. ( 29355984 )
2018
17
Systemic sclerosis: severe pulmonary arterial hypertension and pericardial effusion at diagnosis. ( 29764826 )
2018
18
Massive pericardial effusion without cardiac tamponade due to subclinical hypothyroidism (Hashimoto's disease). ( 29778090 )
2018
19
Treatable massive pericardial effusion and hypertrophic cardiomyopathy in an infant with a novel homozygous ACADVL mutation: A case report. ( 29768383 )
2018
20
Pericardial effusion unrelated to surgery is a predictor of mortality in heart transplant patients. ( 29341061 )
2018
21
Atypical Presentation of a Large Pericardial Effusion after Heart Transplantation in a Patient with Dilated Cardiomyopathy. ( 29429930 )
2018
22
Pericardial effusion as an atypical initial presentation of extra-gonadal nonseminomatous germ cell tumor: a case report and literature review. ( 29492268 )
2018
23
Cough as the sole manifestation of pericardial effusion. ( 29437733 )
2018
24
Massive Hemorrhagic Pericardial Effusion With Cardiac Tamponade as Initial Manifestation of Mixed Connective Tissue Disease. ( 29479391 )
2018
25
Non-small cell lung carcinoma metastatic cells in a pericardial effusion. ( 29714042 )
2018
26
Large pericardial effusion and tamponade in young male with Niemann-Pick disease type C. ( 29898264 )
2018
27
Pericardial effusion in community-acquired pneumonia: Casuality or etiology? ( 29859646 )
2018
28
A rare cause of pericardial effusion due to intracardiac cement embolism. ( 29718318 )
2018
29
Non-operative management is feasible for selected blunt trauma patients with pericardial effusion. ( 29191668 )
2018
30
Non-surgical management in hemodynamically unstable blunt traumatic pericardial effusion: A feasible option for treatment. ( 29980487 )
2018
31
Acute Decompensation after Hemodialysis in a Patient with Pericardial Effusion. ( 29714100 )
2018
32
The Echocardiographic Characteristics and Prognostic Significance of Pericardial Effusions in Eisenmenger Syndrome. ( 28882496 )
2017
33
Large Pericardial Mass Mimicking Pericardial Effusion. ( 29184620 )
2017
34
Diagnosis of systemic inflammatory diseases among patients admitted for acute pericarditis with pericardial effusion. ( 28937580 )
2017
35
Chondrosarcoma: Extrinsic Compression of the Right Ventricle and Pericardial Effusion. ( 28709860 )
2017
36
Case of generalized pustular psoriasis presenting with both pleural effusion and pericardial effusion collection. ( 28636215 )
2017
37
Drug-Induced by Systemic Lupus Erythematosus Presenting as Recurrent Pericardial Effusion After Mitral Valve Repair. ( 29202555 )
2017
38
Infantile Systemic Hyalinosis Complicated with Right Atrial Thrombus and Pericardial Effusion in an Infant. ( 25458638 )
2017
39
Factors Affecting Survival in Children With Pericardial Effusion After Hematopoietic Stem Cell Transplantation. ( 29338379 )
2017
40
Pericardial Effusion: A Rare Side Effect of TNF-Alpha Blocking Agent. ( 28742729 )
2017
41
Tacrolimus as a Rare Cause of Pericardial Effusion in a Renal Transplant Recipient. ( 29326779 )
2017
42
Ethanol injection into the Marshall vein provoking a pericardial effusion resulting in a fatal complication in a patient with persistent atrial fibrillation. ( 28878915 )
2017
43
ANA-Negative Hydralazine-Induced Pericardial Effusion. ( 29391867 )
2017
44
Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease: Insights and pathophysiology. ( 28873222 )
2017
45
Prevalence of vomiting in dogs with pericardial effusion. ( 28079972 )
2017
46
Upper gastrointestinal tract symptoms are predictors of postoperative large pericardial effusion in cardiac surgery. ( 28839323 )
2017
47
Use of Yunnan Baiyao and epsilon aminocaproic acid in dogs with right atrial masses and pericardial effusion. ( 27669112 )
2017
48
Pericardial Effusion as a Presenting Symptom of Hashimoto Thyroiditis: A Case Report. ( 29240719 )
2017
49
Huge pericardial effusion with subcutaneous emphysema, pneumomediastinum and pneumopericardium in anorexia nervosa. ( 28799456 )
2017
50
Intra-Pericardial Use of Recombinant Factor VIIa in a Patient With Acute Hemorrhagic Pericardial Effusion Following Transcutaneous Aortic Valve Replacement-A Case Report. ( 28934519 )
2017

Variations for Pericardial Effusion

ClinVar genetic disease variations for Pericardial Effusion:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 NLRP3 NM_001079821.2(NLRP3): c.1805A> G (p.Gln602Arg) single nucleotide variant Likely pathogenic rs1057518827 GRCh37 Chromosome 1, 247588550: 247588550
2 NLRP3 NM_001079821.2(NLRP3): c.1805A> G (p.Gln602Arg) single nucleotide variant Likely pathogenic rs1057518827 GRCh38 Chromosome 1, 247425248: 247425248

Expression for Pericardial Effusion

Search GEO for disease gene expression data for Pericardial Effusion.

Pathways for Pericardial Effusion

Pathways related to Pericardial Effusion according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.24 FGF2 HIF1A IL6 TNFRSF1A VEGFA
2
Show member pathways
11.87 FGF2 NPPA NPPB TNFRSF1A
3 11.85 FGF2 IL6 VEGFA
4 11.65 FGF2 HIF1A REN
5
Show member pathways
11.52 ADA HIF1A VEGFA
6 11.51 FGF2 HIF1A IL6 VEGFA
7
Show member pathways
11.45 IL6 TNFRSF1A VEGFA
8 11.34 HIF1A IL6 VEGFA
9 11.29 FGF2 IL6 VEGFA
10 11.24 FGF2 PIK3C2A VEGFA
11 10.92 HIF1A IL6 NPPA VEGFA
12
Show member pathways
10.91 CRP HIF1A VEGFA
13 10.9 NPPA NPPB
14 10.82 CRP IL6
15 10.51 FGF2 HIF1A VEGFA
16 10.46 HIF1A VEGFA

GO Terms for Pericardial Effusion

Cellular components related to Pericardial Effusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 CRP FGF2 IL6 MUC16 NLRP3 NPPA
2 extracellular space GO:0005615 9.32 ADA CRP FGF2 IL6 MUC16 NPPA

Biological processes related to Pericardial Effusion according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.92 CRP IL6 NLRP3 TNFRSF1A
2 positive regulation of gene expression GO:0010628 9.91 CRP HIF1A IL6 VEGFA
3 regulation of signaling receptor activity GO:0010469 9.77 FGF2 IL6 NPPA NPPB VEGFA
4 negative regulation of inflammatory response GO:0050728 9.73 ADA NLRP3 TNFRSF1A
5 defense response to Gram-positive bacterium GO:0050830 9.72 CRP IL6 NLRP3
6 regulation of blood pressure GO:0008217 9.67 NPPA NPPB REN
7 positive regulation of endothelial cell proliferation GO:0001938 9.65 FGF2 HIF1A VEGFA
8 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.63 IL6 TNFRSF1A VEGFA
9 positive regulation of heart rate GO:0010460 9.62 ADA NPPA
10 camera-type eye morphogenesis GO:0048593 9.61 HIF1A VEGFA
11 positive regulation of neuroblast proliferation GO:0002052 9.6 HIF1A VEGFA
12 positive regulation of chemokine production GO:0032722 9.59 HIF1A IL6
13 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.58 HIF1A VEGFA
14 regulation of blood vessel size GO:0050880 9.58 NPPA NPPB
15 cell migration involved in sprouting angiogenesis GO:0002042 9.57 FGF2 VEGFA
16 receptor guanylyl cyclase signaling pathway GO:0007168 9.52 NPPA NPPB
17 negative regulation of lipid storage GO:0010888 9.51 CRP IL6
18 response to hypoxia GO:0001666 9.46 ADA HIF1A NPPA VEGFA
19 negative regulation of thymocyte apoptotic process GO:0070244 9.43 ADA HIF1A
20 positive regulation of blood vessel endothelial cell migration GO:0043536 9.43 FGF2 HIF1A VEGFA
21 positive regulation of T-helper 2 cell cytokine production GO:2000553 9.4 IL6 NLRP3
22 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061419 9.32 HIF1A VEGFA
23 positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 9.13 FGF2 PIK3C2A VEGFA
24 cytokine-mediated signaling pathway GO:0019221 9.02 FGF2 HIF1A IL6 TNFRSF1A VEGFA
25 positive regulation of transcription by RNA polymerase II GO:0045944 10.01 FGF2 HIF1A IL6 NLRP3 TNFRSF1A VEGFA

Molecular functions related to Pericardial Effusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone receptor binding GO:0051427 8.62 NPPA NPPB

Sources for Pericardial Effusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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