MCID: PRC012
MIFTS: 53

Pericardial Effusion

Categories: Cardiovascular diseases

Aliases & Classifications for Pericardial Effusion

MalaCards integrated aliases for Pericardial Effusion:

Name: Pericardial Effusion 12 29 55 6 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:118
MeSH 44 D010490
NCIt 50 C3319
SNOMED-CT 68 70370001
ICD10 33 I31.3
UMLS 73 C0031039

Summaries for Pericardial Effusion

Disease Ontology : 12 A pericardium disease that is characterized by an abnormal accumulation of fluid in the pericardial cavity.

MalaCards based summary : Pericardial Effusion is related to cardiac tamponade and constrictive pericarditis. An important gene associated with Pericardial Effusion is ADA (Adenosine Deaminase), and among its related pathways/superpathways are Human cytomegalovirus infection and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Rivaroxaban and Colchicine have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and t cells, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 76 Pericardial effusion ("fluid around the heart") is an abnormal accumulation of fluid in the pericardial... more...

Related Diseases for Pericardial Effusion

Diseases in the Pericardial Effusion family:

Pericardial Effusion, Chronic

Diseases related to Pericardial Effusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 415)
# Related Disease Score Top Affiliating Genes
1 cardiac tamponade 32.4 NPPB REN TNFRSF1A
2 constrictive pericarditis 30.8 ADA NPPB
3 pericarditis 30.5 ADA CRP IL6 NPPB TNFRSF1A
4 endocarditis 30.3 CRP IL6 PIK3C2A
5 pneumonia 30.2 CRP IL6 PIK3C2A
6 hemangioma 30.1 FGF2 HIF1A VEGFA
7 kawasaki disease 30.1 CRP IL6 NPPB
8 pulmonary hypertension 30.0 HIF1A NPPA NPPB REN
9 inferior myocardial infarction 29.9 NPPB PIK3C2A
10 endometrial adenocarcinoma 29.9 FGF2 HIF1A VEGFA
11 meningitis 29.9 ADA CRP IL6 NLRP3
12 myeloma, multiple 29.9 CRP FGF2 IL6 VEGFA
13 castleman disease 29.8 CRP IL6 VEGFA
14 kidney disease 29.8 CRP IL6 NPPA NPPB REN
15 metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 29.7 ACADVL CHKB PIK3C2A
16 cardiac rupture 29.7 CHKB CRP
17 behcet syndrome 29.7 ADA CRP IL6 TNFRSF1A
18 esophageal cancer 29.7 CRP FGF2 HIF1A IL6 VEGFA
19 chronic kidney failure 29.7 CRP IL6 NPPA NPPB REN
20 familial mediterranean fever 29.6 CRP NLRP3 TNFRSF1A
21 sleep apnea 29.6 CRP IL6 NPPB REN
22 acute myocardial infarction 29.5 CHKB CRP NPPA NPPB PIK3C2A
23 adult-onset still's disease 29.5 CRP IL6 TNFRSF1A
24 tetralogy of fallot 29.4 CRP NPPA NPPB REN VEGFA
25 dilated cardiomyopathy 29.4 CHKB CRP IL6 NPPA NPPB REN
26 myocardial infarction 29.2 CHKB CRP HIF1A IL6 NPPA NPPB
27 heart disease 29.2 CRP IL6 NPPA NPPB PIK3C2A REN
28 pericardial effusion, chronic 12.5
29 hemopericardium 12.4
30 cantu syndrome 11.5
31 lymphedema, hereditary, iii 11.4
32 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 11.3
33 dressler's syndrome 11.3
34 pericardial tuberculosis 11.3
35 hereditary multiple osteochondromas 11.3
36 hypothyroidism 10.5
37 lymphoma 10.4
38 lung cancer 10.3
39 atrial fibrillation 10.3
40 angiosarcoma 10.3
41 arthritis 10.3
42 myxedema 10.3
43 adenocarcinoma 10.3
44 gastrointestinal tuberculosis 10.2 ADA CRP
45 chronic meningitis 10.2 CRP NLRP3
46 abdominal tuberculosis 10.2 ADA CRP
47 rheumatoid arthritis 10.2
48 down syndrome 10.2
49 leukemia 10.2
50 schnitzler syndrome 10.2 CRP NLRP3

Graphical network of the top 20 diseases related to Pericardial Effusion:



Diseases related to Pericardial Effusion

Symptoms & Phenotypes for Pericardial Effusion

MGI Mouse Phenotypes related to Pericardial Effusion:

46 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.25 ACADVL ADA CHKB CRP FGF2 HIF1A
2 cardiovascular system MP:0005385 10.24 ACADVL ADA CRP FGF2 HIF1A IL6
3 behavior/neurological MP:0005386 10.16 ACADVL CHKB FGF2 HIF1A IL6 PIK3C2A
4 hematopoietic system MP:0005397 10.16 ADA FGF2 HIF1A IL6 NLRP3 NPPA
5 cellular MP:0005384 10.13 ACADVL ADA FGF2 HIF1A IL6 NLRP3
6 immune system MP:0005387 10.06 ADA CRP HIF1A IL6 NLRP3 PIK3C2A
7 muscle MP:0005369 10.02 ACADVL ADA CHKB FGF2 HIF1A IL6
8 liver/biliary system MP:0005370 9.91 ACADVL ADA HIF1A IL6 NLRP3 TNFRSF1A
9 nervous system MP:0003631 9.81 CHKB FGF2 HIF1A IL6 NLRP3 PIK3C2A
10 neoplasm MP:0002006 9.73 ACADVL FGF2 HIF1A IL6 TNFRSF1A VEGFA
11 renal/urinary system MP:0005367 9.61 ADA HIF1A IL6 NLRP3 NPPA PIK3C2A
12 skeleton MP:0005390 9.23 ADA CHKB FGF2 HIF1A IL6 NLRP3

Drugs & Therapeutics for Pericardial Effusion

Drugs for Pericardial Effusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 230)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Rivaroxaban Approved Phase 4,Phase 3 366789-02-8
2
Colchicine Approved Phase 4,Phase 3,Phase 2 64-86-8 6167 2833
3
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
4
Mycophenolic acid Approved Phase 4 24280-93-1 446541
5
Everolimus Approved Phase 4 159351-69-6 6442177
6
Sirolimus Approved, Investigational Phase 4 53123-88-9 46835353 6436030 5284616
7
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
8
Amiodarone Approved, Investigational Phase 4,Not Applicable 1951-25-3 2157
9
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
10
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
11
gamma-Aminobutyric acid Approved, Investigational Phase 4 56-12-2 119
12
Acetaminophen Approved Phase 4 103-90-2 1983
13
Morphine Approved, Investigational Phase 4 57-27-2 5288826
14
Ibuprofen Approved Phase 4 15687-27-1 3672
15
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
16
Serine Approved, Nutraceutical Phase 4,Phase 3 56-45-1 5951
17
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
18 Kava Approved, Investigational, Nutraceutical Phase 4,Not Applicable 9000-38-8
19 Serine Proteinase Inhibitors Phase 4,Phase 3
20 Factor Xa Inhibitors Phase 4,Phase 3
21
protease inhibitors Phase 4,Phase 3
22 HIV Protease Inhibitors Phase 4,Phase 3
23 Antithrombin III Phase 4,Phase 3
24 Antithrombins Phase 4,Phase 3
25 Anticoagulants Phase 4,Phase 2,Phase 3
26 Antirheumatic Agents Phase 4,Phase 3,Phase 2
27 Antimitotic Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Central Nervous System Depressants Phase 4,Not Applicable
29 Analgesics Phase 4,Phase 3
30 Analgesics, Non-Narcotic Phase 4
31 Peripheral Nervous System Agents Phase 4,Phase 3,Not Applicable
32 Anti-Inflammatory Agents Phase 4,Phase 3
33 Anti-Inflammatory Agents, Non-Steroidal Phase 4
34 Cyclooxygenase Inhibitors Phase 4
35 Cyclosporins Phase 4
36 Antifungal Agents Phase 4
37 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Phase 2
38 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 1,Phase 2
39 Anti-Infective Agents Phase 4,Phase 3,Phase 1,Phase 2
40 Immunologic Factors Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
41 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Phase 1
42 Antitubercular Agents Phase 4
43 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Not Applicable
44 Cytochrome P-450 CYP3A Inhibitors Phase 4,Not Applicable
45 Potassium Channel Blockers Phase 4,Not Applicable
46 Diuretics, Potassium Sparing Phase 4,Not Applicable
47 Sodium Channel Blockers Phase 4,Not Applicable
48 Cytochrome P-450 Enzyme Inhibitors Phase 4,Not Applicable
49 Anti-Arrhythmia Agents Phase 4,Phase 3,Not Applicable
50 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Not Applicable

Interventional clinical trials:

(show top 50) (show all 179)
# Name Status NCT ID Phase Drugs
1 The Effect of Chest Tubes Using Active Clearance Technology® on the Incidence of Postoperative Atrial Fibrillation Unknown status NCT02808897 Phase 4
2 SmartTouch Catheter for Left Anterior Line - SmarT Line Study Unknown status NCT02217657 Phase 4
3 Safety and Feasibility of Arrhythmia Ablation Using the Amigo Remote Robotic System as Compared With Manual Ablation Unknown status NCT01834872 Phase 4
4 Evaluation of WATCHMAN Left Atrial Appendage Occlusion Device in Patients With Atrial Fibrillation Versus Rivaroxaban Unknown status NCT02549963 Phase 4 Rivaroxaban
5 Non Steroidal Anti Inflammatory Treatment for Post Operative Pericardial Effusion Completed NCT00247052 Phase 4 diclofenac;diclofenac;matching placebo
6 Cochicine Treatment for Post- Operative Pericardial Effusion Completed NCT01266694 Phase 4 Colchicines;Placebo
7 Everolimus in de Novo Heart Transplant Recipients Completed NCT01017029 Phase 4 Everolimus;Mycophenolate mofetil + Everolimus
8 Prevention of Atrial Fibrillation Following Esophagectomy Completed NCT00420017 Phase 4 Amiodarone
9 NAVISTAR® THERMOCOOL® Catheter Post Approval Registry Completed NCT00964392 Phase 4
10 Catheter Evaluation for Endocardial Ablation in Patients With Typical Atrial Flutter Completed NCT00318565 Phase 4
11 Study Evaluating the Effiacy of a 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) in Adults Completed NCT00744263 Phase 4
12 Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac Surgery Completed NCT01966172 Phase 4 Ibuprofen;Gabapentin;Morphine;Paracetamol
13 Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension Completed NCT01642407 Phase 4 Sildenafil
14 Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion Recruiting NCT02260206 Phase 4 Colchicine
15 Left Atrial Appendage Closure vs. Novel Anticoagulation Agents in Atrial Fibrillation Recruiting NCT02426944 Phase 4 NOAC
16 Heterotopic Implantation Of the Edwards-Sapien Transcatheter Aortic Valve in the Inferior VEna Cava for the Treatment of Severe Tricuspid Regurgitation (HOVER) Recruiting NCT02339974 Phase 4
17 Safety, Tolerability, Pharmacokinetics and Efficacy of Two Different Rates of Subcutanous Remodulin® Dose Titration in Pulmonary Arterial Hypertension Withdrawn NCT02893995 Phase 4 Slow Dose Titration Group of Subcutaneous Treprostinil;Rapid Dose Titration Group of Subcutaneous Treprostinil
18 COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation (COPPS-2 Trial) Unknown status NCT01552187 Phase 3 Colchicine;Placebo
19 ELIGIBLE (Efficacy of Left atrIal Appendage Closure After GastroIntestinal BLEeding) Unknown status NCT01628068 Phase 3
20 Trial of Drainage With or Without Bleomycin Instillation for Malignant Pericardial Effusion Completed NCT00132613 Phase 3 Pericardial instillation of bleomycin after drainage
21 A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis Completed NCT00810849 Phase 3 Prednisolone
22 WATCHMAN Left Atrial Appendage System for Embolic PROTECTion in Patients With Atrial Fibrillation Completed NCT00129545 Phase 2, Phase 3 Warfarin
23 THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation Completed NCT01385202 Phase 3
24 NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation Completed NCT00116428 Phase 3 Antiarrhythmic drug
25 THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation CONTINUED ACCESS Completed NCT01639495 Phase 3
26 Strategy of Continued Versus Interrupted Novel Oral Anti-coagulant at Time of Device Surgery in Patients With Moderate to High Risk of Arterial Thromboembolic Events Completed NCT01675076 Phase 3 Dabigatran;Rivaroxaban;Apixaban
27 Scleroderma: Cyclophosphamide or Transplantation (SCOT) Completed NCT00114530 Phase 2, Phase 3 cyclophosphamide
28 Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer Completed NCT00347412 Phase 3 Paclitaxel and Carboplatin;NOV-002 Injection in combination with Carboplatin vs. Paclitaxel and Carboplatin
29 A Study of Abciximab and Reteplase When Administered Prior to Catherization After a Myocardial Infarction (Finesse) Completed NCT00046228 Phase 3 abciximab placebo; reteplase placebo, abciximab, abciximab;Abciximab; reteplase; abciximab placebo; abciximab;abciximab; reteplase placebo; abciximab placebo; abciximab;abciximab placebo; reteplase placebo, abciximab, abciximab;abciximab; reteplase placebo; abciximab placebo; abciximab;Abciximab; reteplase; abciximab placebo; abciximab
30 Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate Cancer Completed NCT00744497 Phase 3 Placebo;Dasatinib;Docetaxel;Prednisone
31 An Extension of Study Fx-005 Evaluating Long-Term Safety And Clinical Outcomes Of Fx-1006A In Patients With Transthyretin Amyloid Polyneuropathy Completed NCT00791492 Phase 2, Phase 3 Fx-1006A
32 IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion Recruiting NCT02673879 Phase 3
33 Colchicine in Postoperative Fontan Patients Recruiting NCT03575572 Phase 2, Phase 3 Colchicine
34 WAVECREST Post Market Clinical Follow-Up (PMCF) Study Recruiting NCT03204695 Phase 3
35 Dasatinib Holiday for Improved Tolerability Recruiting NCT02890784 Phase 3 dasatinib (SPRYCEL®)
36 International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia Recruiting NCT02724163 Phase 3 Gemtuzumab ozogamicin;Liposomal daunorubicin;Mitoxantrone;Fludarabine;Cytarabine;Busulfan;Cyclophosphamide
37 The Late Presenter Treatment Optimisation Study Not yet recruiting NCT03696160 Phase 3 Biktarvy;Symtuza
38 Rivaroxaban vs. Warfarin for Post Cardiac Surgery Atrial Fibrillation Not yet recruiting NCT03702582 Phase 3 Rivaroxaban;Warfarin
39 nMARQ™ Pulmonary Vein Isolation System for the Treatment of Paroxysmal Atrial Fibrillation Terminated NCT01824394 Phase 3
40 NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation- Treatment Use Study Terminated NCT00721149 Phase 3
41 Ablation of Paroxysmal Atrial Fibrillation Using the Appropriate Contact Force in a Chinese Population Unknown status NCT02493075 Phase 1, Phase 2
42 Combined CABG and Stem-Cell Transplantation for Heart Failure Unknown status NCT00418418 Phase 2
43 Phase I/II Safety Study of IPI-504 in Relapsed/Refractory Stage IIIb, or Stage IV Non-small Cell Lung Cancer (NSCLC) Completed NCT00431015 Phase 1, Phase 2 IPI-504
44 Dasatinib (Sprycel™) in Patients With Newly Diagnosed Core Binding Factor (CBF) Acute Myeloid Leukemia (AML) Completed NCT00850382 Phase 1, Phase 2 Dasatinib;daunorubicin;Cytarabine
45 NGR-hTNF in Combination With Standard Chemotherapy to Treat Patients With Advanced Non-small Cell Lung Cancer Completed NCT00994097 Phase 2 NGR-hTNF;Cisplatin;Gemcitabine;Pemetrexed
46 A Study of Bevacizumab Plus Carboplatin and Paclitaxel in Subjects With Advanced, Previously Untreated, Squamous Non-Small Cell Lung Cancer (BRIDGE) Completed NCT00318136 Phase 2 Bevacizumab;Carboplatin;Paclitaxel
47 Triplet Combination First Line Treatment in Non Small Cell Lung Cancer (NSCLC) Completed NCT00942825 Phase 2 CBP501 + Cisplatin + Pemetrexed;Cisplatin + Pemetrexed
48 Phase II Study of Cetuximab in Combination With Carboplatin and Docetaxel for Patients With Advanced Non-Small Cell Lung Cancer Completed NCT00251498 Phase 2 Cetuximab
49 Safety and Efficacy Evaluation of Two Year Imatinib Treatment in Adjuvant Gastrointestinal Stromal Tumor (GIST) Completed NCT01172548 Phase 2 imatinib mesylate
50 Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer Completed NCT00960999 Phase 2

Search NIH Clinical Center for Pericardial Effusion

Genetic Tests for Pericardial Effusion

Genetic tests related to Pericardial Effusion:

# Genetic test Affiliating Genes
1 Pericardial Effusion 29

Anatomical Context for Pericardial Effusion

MalaCards organs/tissues related to Pericardial Effusion:

41
Lung, Heart, T Cells, Kidney, Myeloid, Thyroid, Liver

Publications for Pericardial Effusion

Articles related to Pericardial Effusion:

(show top 50) (show all 1108)
# Title Authors Year
1
Pericardial effusion in infective endocarditis: The times they are a-changin'. ( 30301562 )
2019
2
Predictors of hospital discharge in cancer patients with pericardial effusion undergoing surgical pericardial drainage. ( 30466137 )
2019
3
Incidence of pericardial effusion after left atrial appendage closure: The impact of underlying heart rhythm-Data from the EWOLUTION study. ( 29722469 )
2018
4
Possible involvement of IL-6-producing tissue-resident macrophages in early-onset pericardial effusion pathogenesis after hematopoietic stem cell transplantation. ( 29384263 )
2018
5
A Case Series of Two Patients Presenting With Pericardial Effusion as First Manifestation of Non-Small Cell Lung Cancer With <i>BRAF</i> Mutation and Expression Of PD-L1. ( 29760834 )
2018
6
Reply to the letter: &amp;quot;Pericardial effusion in community-acquired pneumonia: casuality or etiology?&amp;quot; ( 29735269 )
2018
7
Pericardial effusion following cardiac surgery. A single-center experience. ( 29171276 )
2018
8
Massive pleural and pericardial effusion due to hypothyroidism in a patient with a surgically treated thyroid-stimulating hormone-producing pituitary adenoma. ( 29757110 )
2018
9
Conservative management of nivolumab-induced pericardial effusion: a case report and review of literature. ( 29761026 )
2018
10
Relevant pericardial effusion caused by cytomegalovirus infection in an immunocompetent patient: a case report. ( 29347961 )
2018
11
Pericardial Effusion in Obstructive Sleep Apnea without Pulmonary Arterial Hypertension and Daily Hypoxemia - is it Unusual? ( 29808980 )
2018
12
Idiopathic Loculated and Septated Pericardial Effusion. ( 29871831 )
2018
13
Recurrent Pericardial Effusion While Receiving Nivolumab for Metastatic Lung Adenocarcinoma: Case Report and Review of the Literature. ( 29937384 )
2018
14
Pleural and pericardial effusion in a long-term PD patient - a defying diagnosisa8c. ( 29231161 )
2018
15
Morphology quiz: Pericardial effusion as first manifestation of malignancy. ( 29732625 )
2018
16
Idiosyncratic Pericardial Effusion Associated With Minoxidil. ( 29746289 )
2018
17
Left Atrial Appendage Perforation Does Not Always Mean Pericardial Effusion. ( 29880108 )
2018
18
PCR evaluation of selected vector-borne pathogens in dogs with pericardial effusion. ( 29355984 )
2018
19
Systemic sclerosis: severe pulmonary arterial hypertension and pericardial effusion at diagnosis. ( 29764826 )
2018
20
Massive pericardial effusion without cardiac tamponade due to subclinical hypothyroidism (Hashimoto's disease). ( 29778090 )
2018
21
Treatable massive pericardial effusion and hypertrophic cardiomyopathy in an infant with a novel homozygous ACADVL mutation: A case report. ( 29768383 )
2018
22
Pericardial effusion unrelated to surgery is a predictor of mortality in heart transplant patients. ( 29341061 )
2018
23
Atypical Presentation of a Large Pericardial Effusion after Heart Transplantation in a Patient with Dilated Cardiomyopathy. ( 29429930 )
2018
24
Pericardial effusion as an atypical initial presentation of extra-gonadal nonseminomatous germ cell tumor: a case report and literature review. ( 29492268 )
2018
25
Cough as the sole manifestation of pericardial effusion. ( 29437733 )
2018
26
Massive Hemorrhagic Pericardial Effusion With Cardiac Tamponade as Initial Manifestation of Mixed Connective Tissue Disease. ( 29479391 )
2018
27
Non-small cell lung carcinoma metastatic cells in a pericardial effusion. ( 29714042 )
2018
28
Large pericardial effusion and tamponade in young male with Niemann-Pick disease type C. ( 29898264 )
2018
29
Pericardial effusion in community-acquired pneumonia: Casuality or etiology? ( 29859646 )
2018
30
A rare cause of pericardial effusion due to intracardiac cement embolism. ( 29718318 )
2018
31
Non-operative management is feasible for selected blunt trauma patients with pericardial effusion. ( 29191668 )
2018
32
Non-surgical management in hemodynamically unstable blunt traumatic pericardial effusion: A feasible option for treatment. ( 29980487 )
2018
33
Acute Decompensation after Hemodialysis in a Patient with Pericardial Effusion. ( 29714100 )
2018
34
Autosomal Dominant Polycystic Kidney Disease and Pericardial Effusion. ( 30210723 )
2018
35
Pericardial Effusion due to Infliximab Therapy for Ulcerative Colitis. ( 30533230 )
2018
36
Risk factors of pericardial effusion in native valve infective endocarditis and its influence on outcome: A multicenter prospective cohort study. ( 30122503 )
2018
37
Risk factors for pericardial effusion after chemoradiotherapy for thoracic esophageal cancer-comparison of four-field technique and traditional two opposed fields technique. ( 29659940 )
2018
38
Predictors and Outcome of Pericardial Effusion After Hematopoietic Stem Cell Transplantation in Children. ( 29058031 )
2018
39
A case of hypertensive emergency, primary hypothyroidism and large pericardial effusion with early tamponade. ( 30279905 )
2018
40
Massive pericardial effusion caused by hypothyroidism. ( 29636960 )
2018
41
Pericardial effusion as first presentation of disseminated non-Hodgkin's lymphoma. ( 30287628 )
2018
42
Fever and large pericardial effusion after valve surgery: can be malaria. ( 30269522 )
2018
43
Cellular fraction analysis of pericardial effusion helps the diagnosis of eosinophilic myocarditis. ( 30457083 )
2018
44
Massive pericardial effusion: A rare and easily missed finding in myocardial perfusion scintigraphy. ( 30034286 )
2018
45
Rapid Fire: Pericardial Effusion and Tamponade. ( 30037442 )
2018
46
Pericardial effusion in Hodgkin lymphoma: a report from the Children's Oncology Group AHOD0031 protocol. ( 30061157 )
2018
47
Intrapericardial cisplatin combined with oral colchicine resulted in long term control of malignant pericardial effusion in the course of metastatic renal cancer. ( 30110119 )
2018
48
A Case of Persistent Right Ventricular Failure after Rapid Decompression of a Large Chronic Pericardial Effusion. ( 30128413 )
2018
49
Pericardial Effusion & Electrical Alternans. ( 30165695 )
2018
50
Bilateral chylothorax and pericardial effusion following subtotal gastrectomy in a patient with situs inversus totalis. ( 30192067 )
2018

Variations for Pericardial Effusion

ClinVar genetic disease variations for Pericardial Effusion:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 NLRP3 NM_001079821.2(NLRP3): c.1805A> G (p.Gln602Arg) single nucleotide variant Likely pathogenic rs1057518827 GRCh37 Chromosome 1, 247588550: 247588550
2 NLRP3 NM_001079821.2(NLRP3): c.1805A> G (p.Gln602Arg) single nucleotide variant Likely pathogenic rs1057518827 GRCh38 Chromosome 1, 247425248: 247425248

Expression for Pericardial Effusion

Search GEO for disease gene expression data for Pericardial Effusion.

Pathways for Pericardial Effusion

Pathways related to Pericardial Effusion according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.81 FGF2 HIF1A IL6 TNFRSF1A VEGFA
2 11.85 FGF2 IL6 VEGFA
3
Show member pathways
11.82 FGF2 NPPA NPPB TNFRSF1A
4 11.64 FGF2 HIF1A REN
5 11.51 FGF2 HIF1A IL6 VEGFA
6
Show member pathways
11.5 ADA HIF1A VEGFA
7
Show member pathways
11.43 IL6 TNFRSF1A VEGFA
8 11.32 HIF1A IL6 VEGFA
9 11.26 FGF2 IL6 VEGFA
10 11.21 FGF2 PIK3C2A VEGFA
11 10.92 HIF1A IL6 NPPA VEGFA
12
Show member pathways
10.91 CRP HIF1A VEGFA
13 10.9 NPPA NPPB
14 10.82 CRP IL6
15 10.51 FGF2 HIF1A VEGFA
16 10.45 HIF1A VEGFA

GO Terms for Pericardial Effusion

Cellular components related to Pericardial Effusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 CRP FGF2 IL6 MUC16 NLRP3 NPPA
2 extracellular space GO:0005615 9.32 ADA CRP FGF2 IL6 MUC16 NPPA

Biological processes related to Pericardial Effusion according to GeneCards Suite gene sharing:

(show all 27)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.89 CRP IL6 NLRP3 TNFRSF1A
2 positive regulation of angiogenesis GO:0045766 9.81 FGF2 HIF1A VEGFA
3 regulation of signaling receptor activity GO:0010469 9.77 FGF2 IL6 NPPA NPPB VEGFA
4 negative regulation of inflammatory response GO:0050728 9.74 ADA NLRP3 TNFRSF1A
5 defense response to Gram-positive bacterium GO:0050830 9.72 CRP IL6 NLRP3
6 positive regulation of endothelial cell proliferation GO:0001938 9.65 FGF2 HIF1A VEGFA
7 camera-type eye morphogenesis GO:0048593 9.63 HIF1A VEGFA
8 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.63 IL6 TNFRSF1A VEGFA
9 dopaminergic neuron differentiation GO:0071542 9.62 HIF1A VEGFA
10 positive regulation of heart rate GO:0010460 9.62 ADA NPPA
11 positive regulation of neuroblast proliferation GO:0002052 9.61 HIF1A VEGFA
12 cell migration involved in sprouting angiogenesis GO:0002042 9.61 FGF2 VEGFA
13 regulation of blood pressure GO:0008217 9.61 NPPA NPPB REN
14 positive regulation of chemokine production GO:0032722 9.6 HIF1A IL6
15 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.58 HIF1A VEGFA
16 regulation of blood vessel size GO:0050880 9.58 NPPA NPPB
17 cGMP biosynthetic process GO:0006182 9.54 NPPA NPPB
18 receptor guanylyl cyclase signaling pathway GO:0007168 9.52 NPPA NPPB
19 negative regulation of lipid storage GO:0010888 9.51 CRP IL6
20 negative regulation of thymocyte apoptotic process GO:0070244 9.49 ADA HIF1A
21 response to hypoxia GO:0001666 9.46 ADA HIF1A NPPA VEGFA
22 positive regulation of blood vessel endothelial cell migration GO:0043536 9.43 FGF2 HIF1A VEGFA
23 positive regulation of T-helper 2 cell cytokine production GO:2000553 9.4 IL6 NLRP3
24 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061419 9.32 HIF1A VEGFA
25 positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 9.13 FGF2 PIK3C2A VEGFA
26 cytokine-mediated signaling pathway GO:0019221 9.02 FGF2 HIF1A IL6 TNFRSF1A VEGFA
27 positive regulation of transcription by RNA polymerase II GO:0045944 10.03 FGF2 HIF1A IL6 NLRP3 TNFRSF1A VEGFA

Molecular functions related to Pericardial Effusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone receptor binding GO:0051427 8.62 NPPA NPPB

Sources for Pericardial Effusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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