MCID: PRC012
MIFTS: 51

Pericardial Effusion

Categories: Cardiovascular diseases

Aliases & Classifications for Pericardial Effusion

MalaCards integrated aliases for Pericardial Effusion:

Name: Pericardial Effusion 12 54 6 15 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:118
MeSH 43 D010490
NCIt 49 C3319
SNOMED-CT 67 70370001
ICD10 32 I31.3
UMLS 71 C0031039

Summaries for Pericardial Effusion

Disease Ontology : 12 A pericardium disease that is characterized by an abnormal accumulation of fluid in the pericardial cavity.

MalaCards based summary : Pericardial Effusion is related to pericardial tuberculosis and cardiac tamponade. An important gene associated with Pericardial Effusion is ADA (Adenosine Deaminase), and among its related pathways/superpathways are MicroRNAs in cardiomyocyte hypertrophy and Interleukin-4 and 13 signaling. The drugs Diclofenac and Tadalafil have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and kidney, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 74 Pericardial effusion ("fluid around the heart") is an abnormal accumulation of fluid in the pericardial... more...

Related Diseases for Pericardial Effusion

Diseases in the Pericardial Effusion family:

Pericardial Effusion, Chronic

Diseases related to Pericardial Effusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 932)
# Related Disease Score Top Affiliating Genes
1 pericardial tuberculosis 33.4 CRP ADA
2 cardiac tamponade 32.0 TNNI3 TNFRSF1A REN PVR PIK3C2A NPPB
3 myxedema 31.5 PIK3C2A NPPA MUC16
4 cardiogenic shock 31.3 NPPB IL6 CRP
5 pericarditis 31.2 TNNI3 TNFRSF1A NPPB IL6 CRP ALB
6 infective endocarditis 31.1 TNNI3 IL6 CRP
7 hypothyroidism 31.1 VEGFA REN PIK3C2A CRP CHKB ALB
8 constrictive pericarditis 31.0 TNNI3 NPPB CRP ALB ADA ACE
9 acute kidney failure 31.0 REN PIK3C2A NPPA ALB
10 endocarditis 31.0 TNNI3 PIK3C2A IL6 CRP ALB
11 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 31.0 PIK3C2A CHKB ACADVL
12 pulmonary tuberculosis 30.9 IL6 CRP ALB ADA
13 atrial standstill 1 30.9 TNNI3 NPPB NPPA ACE ACADVL
14 pleural empyema 30.9 CRP ALB ADA
15 connective tissue disease 30.9 VEGFA IL6 CRP ALB ACE
16 familial mediterranean fever 30.9 TNFRSF1A NLRP3 IL6 CRP
17 uremia 30.9 REN IL6 CRP ALB ACE
18 brucellosis 30.8 IL6 CRP ADA
19 mediastinitis 30.8 PVR CRP ALB
20 acquired immunodeficiency syndrome 30.8 TNFRSF1A IL6 CRP ALB ADA
21 yellow nail syndrome 30.8 ALB ADA
22 rheumatic heart disease 30.8 NPPB IL6 ACE
23 chronic thromboembolic pulmonary hypertension 30.8 NPPB CRP
24 kawasaki disease 30.8 NPPB IL6 CRP ALB
25 mitral valve stenosis 30.7 REN NPPB NPPA CRP ACE
26 juvenile rheumatoid arthritis 30.7 TNFRSF1A IL6 CRP ALB
27 myeloma, multiple 30.7 VEGFA TNFRSF1A IL6 FGF2 CRP ALB
28 cardiac arrest 30.7 REN PIK3C2A NPPB ALB ACE
29 kaposi sarcoma 30.7 VEGFA IL6 HIF1A FGF2
30 adult-onset still's disease 30.7 TNFRSF1A IL6 CRP
31 atrioventricular block 30.7 TNNI3 PIK3C2A NPPB ACE
32 meningitis 30.6 VEGFA NLRP3 IL6 CRP ALB ADA
33 systemic autoimmune disease 30.6 IL6 CRP
34 coronary heart disease 1 30.6 NPPB IL6 CRP ACE
35 ovarian hyperstimulation syndrome 30.5 VEGFA REN IL6 ALB
36 polycystic kidney disease 30.5 VEGFA REN ALB ACE
37 conjunctivitis 30.5 NLRP3 MUC16 IL6
38 tricuspid valve insufficiency 30.5 TNNI3 NPPB CRP ALB ACE
39 bacterial meningitis 30.5 PIK3C2A IL6 CRP ALB
40 arthritis 30.5 VEGFA TNFRSF1A IL6 CRP ALB
41 leishmaniasis 30.5 TNFRSF1A IL6 CRP ALB
42 oligohydramnios 30.5 REN NPPB ACE
43 gastroenteritis 30.5 REN IL6 CRP ALB
44 myocarditis 30.5 TNNI3 PIK3C2A NPPB NPPA IL6 ALB
45 crohn's disease 30.5 NLRP3 IL6 CRP ALB
46 persistent fetal circulation syndrome 30.5 VEGFA IL6 ALB
47 plasma cell neoplasm 30.5 VEGFA IL6 ALB
48 interstitial lung disease 30.5 NPPB IL6 CRP ALB
49 collagen disease 30.5 NPPA IL6 CRP ACE
50 exanthem 30.5 VEGFA PIK3C2A NLRP3 IL6 CRP ALB

Graphical network of the top 20 diseases related to Pericardial Effusion:



Diseases related to Pericardial Effusion

Symptoms & Phenotypes for Pericardial Effusion

MGI Mouse Phenotypes related to Pericardial Effusion:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.3 ACADVL ACE ADA ALB CRP FGF2
2 homeostasis/metabolism MP:0005376 10.28 ACADVL ACE ADA ALB CHKB CRP
3 hematopoietic system MP:0005397 10.17 ACE ADA FGF2 HIF1A IL6 NLRP3
4 immune system MP:0005387 10.11 ACE ADA ALB CRP HIF1A IL6
5 mortality/aging MP:0010768 10.07 ACADVL ACE ADA ALB FGF2 HIF1A
6 liver/biliary system MP:0005370 9.97 ACADVL ACE ADA ALB HIF1A IL6
7 muscle MP:0005369 9.93 ACADVL ADA ALB CHKB FGF2 HIF1A
8 neoplasm MP:0002006 9.56 ACADVL ACE ALB FGF2 HIF1A IL6
9 renal/urinary system MP:0005367 9.36 ACE ADA ALB HIF1A IL6 NLRP3

Drugs & Therapeutics for Pericardial Effusion

Drugs for Pericardial Effusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 164)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
2
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
3
Silver sulfadiazine Approved, Vet_approved Phase 4 22199-08-2 441244
4
Ambrisentan Approved, Investigational Phase 4 177036-94-1 6918493
5
Treprostinil Approved, Investigational Phase 4 81846-19-7 54786 6918140
6
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
7
Dabigatran Investigational Phase 4 211914-51-1
8 Phosphodiesterase 5 Inhibitors Phase 4
9 Phosphodiesterase Inhibitors Phase 4
10 Antihypertensive Agents Phase 4
11 Antirheumatic Agents Phase 4
12 Anti-Inflammatory Agents Phase 4
13 Anti-Inflammatory Agents, Non-Steroidal Phase 4
14 Analgesics, Non-Narcotic Phase 4
15 Cyclooxygenase Inhibitors Phase 4
16 Analgesics Phase 4
17 Fibrinolytic Agents Phase 4
18 HIV Protease Inhibitors Phase 4
19 Antithrombins Phase 4
20
protease inhibitors Phase 4
21 Antipyretics Phase 4
22 Platelet Aggregation Inhibitors Phase 4
23 Serine Proteinase Inhibitors Phase 4
24 Anticoagulants Phase 4
25 Antithrombin III Phase 4
26
Serine Investigational, Nutraceutical Phase 4 56-45-1 5951
27
Cetrorelix Approved, Investigational Phase 2, Phase 3 120287-85-6 16129715 25074887
28
Bleomycin Approved, Investigational Phase 3 11056-06-7 5360373
29
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
30
Carboplatin Approved Phase 3 41575-94-4 10339178 498142 38904
31
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
32
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5
33
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
34 Prednisolone acetate Approved, Vet_approved Phase 3 52-21-1
35
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
36
Colchicine Approved Phase 3 64-86-8 6167 2833
37
Prednisolone hemisuccinate Experimental Phase 3 2920-86-7
38 Fertility Agents Phase 2, Phase 3
39 Sclerosing Solutions Phase 3
40 Albumin-Bound Paclitaxel Phase 3
41 Vaccines Phase 3
42 Antiemetics Phase 3
43 Methylprednisolone Acetate Phase 3
44 Gastrointestinal Agents Phase 3
45 Hormone Antagonists Phase 3
46 Neuroprotective Agents Phase 3
47 Antineoplastic Agents, Hormonal Phase 3
48 glucocorticoids Phase 3
49 Protective Agents Phase 3
50 Plasminogen Phase 3

Interventional clinical trials:

(show top 50) (show all 96)
# Name Status NCT ID Phase Drugs
1 Atrial Fibrillation and Pericardial Drainage: Incidence of Postoperative Atrial Fibrillation According to the Type of Mediastinal Drainage Catheters Unknown status NCT02808897 Phase 4
2 Cochicine Treatment for Post- Operative Pericardial Effusion: The POPE 2 Study A Multicenter, Double-blind, Randomized Trial Completed NCT01266694 Phase 4 Colchicines;Placebo
3 the Post Operative Pericardial Effusion (POPE) Treatment Study Completed NCT00247052 Phase 4 diclofenac;diclofenac;matching placebo
4 A Controlled Randomized Trial of Circumferential Pulmonary Vein Ablation Versus Antiarrhythmic Drug Therapy in Treating Paroxysmal Atrial Fibrillation. The Ablation for Paroxysmal Atrial Fibrillation (APAF2) Trial Completed NCT00340314 Phase 4 Antiarrhythmic Drug Therapy
5 A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis Completed NCT01042158 Phase 4 tadalafil and ambrisentan upfront combination therapy
6 Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion Following Catheter Ablation of Atrial Fibrillation Recruiting NCT02260206 Phase 4 Colchicine
7 Comparison of Amplatzer Amulet vs Watchman Device in Patients Undergoing Left Atrial Appendage Closure: the SWISS-APERO Randomized Clinical Trial Recruiting NCT03399851 Phase 4
8 Effects of Treprostinil on Right Ventricular Structure and Function in Patients With Pulmonary Arterial Hypertension Recruiting NCT03835676 Phase 4 Treprostinil
9 Interventional Left Atrial Appendage Closure vs. Novel Anticoagulation Agents in High-risk Patients With Atrial Fibrillation (PRAGUE-17 Study) Recruiting NCT02426944 Phase 4 NOAC
10 Efficacy of Short Term Dabigatran Etexilate Followed by Aspirin Monotherapy After LAA (Left Atrial Appendage) Device Closure (the DEA-LAA Study). Active, not recruiting NCT03539055 Phase 4 Dabigatran Etexilate Oral Capsule
11 COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation (COPPS-2 Trial). Unknown status NCT01552187 Phase 3 Colchicine;Placebo
12 Sequential E2 Levels Not Ovarian Maximal Diameter Estimates Were Correlated With Outcome of Cetrotide Therapy for Management of Women at High-risk of Ovarian Hyperstimulation Syndrome Unknown status NCT02823080 Phase 2, Phase 3 Cetrorelix
13 A Randomized Controlled Trial to Evaluate the Efficacy of Intra-pericardial Instillation of a Sclerosing Agent After Pericardial Drainage in Patients With Malignant Pericardial Effusion Associated With Lung Cancer (JCOG9811) Completed NCT00132613 Phase 3 Pericardial instillation of bleomycin after drainage
14 A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis Completed NCT00810849 Phase 3 Prednisolone
15 Phase 3 Trial, Randomized, Open-Label, of NOV-002 in Combination With Paclitaxel and Carboplatin vs. Paclitaxel and Carboplatin Alone for the Treatment of Advanced Non-Small-Cell Lung Cancer (NSCLC) Completed NCT00347412 Phase 3 Paclitaxel and Carboplatin;NOV-002 Injection in combination with Carboplatin vs. Paclitaxel and Carboplatin
16 A Trial of Complete Percutaneous Pericardial Drainage Facilitated by Intrapericardial Alteplase Compared to Conventional Pericardiocentesis When Indicated in Adults With Large Pericardial Effusion Due to Tuberculous and Non-tuberculous Pericarditis Recruiting NCT02673879 Phase 3
17 Colchicine Versus Placebo in Post-Cardiac Surgery Patients to Prevent Post-Pericardiotomy Syndrome and Atrial Fibrillation Terminated NCT02177266 Phase 3 Colchicine;Placebo
18 Ablation of Paroxysmal Atrial Fibrillation Using the Appropriate Contact Force in a Chinese Population: A Prospective Randomized Single-center Trial Unknown status NCT02493075 Phase 1, Phase 2
19 Intrapleural Bevacizumab Injection for Treating Malignant Pleural or Pericardial Effusion in Non-small Cell Lung Cancer Completed NCT02054052 Phase 2 Bevacizumab
20 A Pilot Study of Bevacizumab Plus Carboplatin and Paclitaxel in Subjects With Advanced, Previously Untreated, Squamous Non-Small Cell Lung Cancer Completed NCT00318136 Phase 2 Bevacizumab;Carboplatin;Paclitaxel
21 Phase II Study of Cetuximab in Combination With Carboplatin and Docetaxel for Patients With Advanced Non-Small Cell Lung Cancer Completed NCT00251498 Phase 2 Cetuximab
22 A Phase I/II Study to Investigate the Safety, Tolerability and Potential Activity of IPI-504 in Relapsed and / or Refractory Stage IIIb (With Malignant Pleural or Pericardial Effusion), or Stage IV NSCLC Patients Completed NCT00431015 Phase 1, Phase 2 IPI-504
23 Amgen Protocol 20060534 - A Phase 1b/2 Trial of AMG 479 or AMG 102 in Combination With Platinum-based Chemotherapy as First-Line Treatment for Extensive Stage Small Cell Lung Cancer Completed NCT00791154 Phase 1, Phase 2 AMG 479;Etoposide;Placebo;AMG 102;Carboplatin;Cisplatin
24 NGR014: Randomized Phase II Study of NGR-hTNF in Combination With Standard Chemotherapy Versus Standard Chemotherapy Alone in Previously Untreated Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Completed NCT00994097 Phase 2 NGR-hTNF;Cisplatin;Gemcitabine;Pemetrexed
25 Phase II Study of Everolimus in Combination With Exemestane Versus Everolimus Alone Versus Capecitabine in the Treatment of Postmenopausal Women With ER+Locally Advanced, Recurrent, or Metastatic Breast Cancer After Recurrence or Progression on Prior Letrozole or Anastrozole. Completed NCT01783444 Phase 2 Capecitabine;Exemestane;Everolimus
26 A Randomized Phase II Trial of Paclitaxel-Carboplatin or Gemicitabine-Cisplatin in ECOG Performance Status 2 Non-Small Cell Lung Cancer Patients Completed NCT00006004 Phase 2 carboplatin;cisplatin;gemcitabine hydrochloride;paclitaxel
27 Phase II Study of a Triplet Combination of CBP501, Pemetrexed and Cisplatin as First Line Treatment in Patients With Stage IV Non-squamous Non Small Cell Lung Cancer (NSCLC) Completed NCT00942825 Phase 2 CBP501 + Cisplatin + Pemetrexed;Cisplatin + Pemetrexed
28 Single Agent Alimta in Poor Performance Status in Patients With Non-Small Cell Lung Cancer (NSCLC) Completed NCT00508144 Phase 2 Alimta
29 A Phase II Randomized Study of OSI-774 (Erlotinib) (NSC #718781) With or Without Carboplatin/Paclitaxel in Patients With Previously Untreated Adenocarcinoma of the Lung Who Never Smoked or Were Former Light Smokers Completed NCT00126581 Phase 2 Carboplatin;Erlotinib;Erlotinib Hydrochloride;Paclitaxel
30 A Phase II Study of Induction (Daunorubicin/Cytarabine) and Consolidation (High-Dose Cytarabine) Chemotherapy Plus Dasatinib (NSC #732517) and Continuation Therapy With Dasatinib Alone in Newly Diagnosed Patients With Core Binding Factor Acute Myeloid Leukemia (AML) Active, not recruiting NCT01238211 Phase 2 Cytarabine;Dasatinib;Daunorubicin Hydrochloride
31 Randomized Phase II Trial of Individualized Adaptive Radiotherapy Using During-Treatment FDG-PET/CT and Modern Technology in Locally Advanced Non-Small Cell Lung Cancer (NSCLC) Active, not recruiting NCT01507428 Phase 2 18F-Fluoromisonidazole;Carboplatin;Fludeoxyglucose F-18;Paclitaxel
32 Hypofractionated Accelerated Radiotherapy With Concomitant Full Dose Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer: Phase I/II Study Active, not recruiting NCT02367443 Phase 1, Phase 2
33 Prevention of Postoperative Cardiac Arrythmias in Thoracic Surgery : Celiprolol Versus Diltiazem Not yet recruiting NCT03752931 Phase 2 Celiprolol;Diltiazem
34 A Prospective, Single Arm, Open Phase II Clinical Trial of Adjuvant Treatment of Stage III Gastric Cancer (PD-L1 + / MSI-H / EB +) With Anti-PD-1 Antibody and First-line Chemotherapy Not yet recruiting NCT04152889 Phase 1, Phase 2 PD-L1 inhibitor+chemotherapy
35 Mesenchymal Stem Cell Administration in the Treatment of Coronary Graft Disease in Heart Transplant Patients Suspended NCT02472002 Phase 1, Phase 2
36 Compassionate Use of Catheter Thrombectomy (Aspirex 11F) in Patients With Massive Pulmonary Embolism Terminated NCT00314002 Phase 1, Phase 2
37 Phase II Trial of ILX295501 Administered Orally Once Weekly x 3 Repeated Every 6 Weeks in Patients With Stage III/IV Ovarian Cancer Withdrawn NCT00005645 Phase 2 ILX-295501
38 Phase I Clinical Trial of Autologous Mesothelin Re-directed T Cells in Patients With Chemotherapy Refractory Metastatic Pancreatic Cancer Completed NCT01897415 Phase 1
39 Collagenase Total Occlusion-1 Trial Completed NCT01271335 Phase 1
40 A Phase I Trial of Herceptin and Interleukin-12 Completed NCT00004074 Phase 1
41 A Phase I, Pharmacokinetic, and Biologic Correlative Study of R115777 (NSC 702818) and Herceptin in Patients With Advanced Cancer Completed NCT00005842 Phase 1 tipifarnib
42 Drainage or Pericardiocentesis Alone for Recurrent Non-malignant Pericardial Effusions Requiring Intervention. Unknown status NCT01665495
43 Clinical Audit of the Management of Pericarditis in Children. Unknown status NCT03253315
44 Functional and Morphological Cardiac Changes in Myeloproliferative Neoplasms Unknown status NCT03177928
45 Improvement of the Etiological Diagnosis of the Pericarditis Unknown status NCT02828085
46 Evaluation of the Cardiac Complications in Congenitally HIV-1 Infected Children in Israel by the Echocardiography and Measurement of N-Terminal Pro-B-Type Natriuretic Peptide (N-BNP). Unknown status NCT00426374
47 The Incidence of Significant Clinical Findings Using Focused Ultrasound Examination for the Heart, Lungs and Abdomen in Elderly Patients Before Emergent Surgery Unknown status NCT02824692
48 Placement Of Cardiac PacemaKer Trial (POCKET)-RCT Unknown status NCT02931760
49 The Italian Society of Invasive Cardiology Registry on Percutaneous Aortic Valve Unknown status NCT02713932
50 Myocardial Adipose Inflammation and Pericardial Adipose Volume as Markers for Coronary Artery Disease In HIV Positive Patients Unknown status NCT02399384

Search NIH Clinical Center for Pericardial Effusion

Genetic Tests for Pericardial Effusion

Anatomical Context for Pericardial Effusion

MalaCards organs/tissues related to Pericardial Effusion:

40
Heart, Lung, Kidney, Breast, T Cells, Thyroid, Liver

Publications for Pericardial Effusion

Articles related to Pericardial Effusion:

(show top 50) (show all 8208)
# Title Authors PMID Year
1
[Differentiation of malignant from nonmalignant, inflammatory pericardial effusions with biomarkers]. 54 61
20024642 2009
2
Adenosine deaminase in the diagnosis of tuberculous pericardial effusion. 54 61
18344697 2008
3
Adenosine deaminase and tuberculous pericarditis--a systematic review with meta-analysis. 54 61
16950165 2006
4
[Analysis of misdiagnosis in 33 cases of aortic dissection]. 54 61
16174592 2005
5
[A case of tuberculous pericarditis, the diagnosis of which was complicated by the delay in the rise of adenosine deaminase in the pericardial effusion]. 54 61
12806984 2003
6
The role of carcinoembryonic antigen (CEA) and neuron-specific enolase (NSE) evaluation in pericardial fluid for the recognition of malignant pericarditis. 54 61
9479590 1997
7
Very long chain acyl-CoA dehydrogenase deficiency: successful treatment of acute cardiomyopathy. 54 61
8809347 1996
8
[The value of measuring adenosine deaminase activity in pericardial effusion fluid for diagnosing the etiology of pericardial effusion]. 54 61
9181887 1996
9
Adenosine deaminase and carcinoembryonic antigen in pericardial effusion diagnosis, especially in suspected tuberculous pericarditis. 54 61
8205688 1994
10
Usefulness of serum CA125 measurement for monitoring pericardial effusion. 54 61
8340995 1993
11
[Serum CA125 measurement is useful in 3 cases with pericardial effusion]. 54 61
8516579 1993
12
[Coronary arterial rupture during percutaneous transluminal coronary angioplasty: a case report]. 54 61
2104423 1990
13
Pathology of radiation induced heart disease. 61
32021573 2020
14
Vagococcus salmoninarum I-A chronic coldwater streptococcosis in broodstock brook trout (Salvelinus fontinalis) in Wisconsin, USA. 61
32030789 2020
15
MRI Radiomics Analysis for Predicting the Pathologic Classification and TNM Staging of Thymic Epithelial Tumors: A Pilot Study. 61
31799873 2020
16
A case of surgery applying a Denver shunt for intractable pericardial effusion. 61
31830421 2020
17
A 63-year-old woman with multiple secondary tumours. 61
31915242 2020
18
Takotsubo cardiomyopathy complicated by cardiac tamponade due to non-hemorrhagic pericardial effusion: a case report. 61
32028901 2020
19
You "Cantu": Multidisciplinary Collaboration Resulting in Successful Orthognathic Surgery. 61
31401848 2020
20
Cardiac point-of-care ultrasound reveals unexpected, life-threatening findings in two children. 61
32016667 2020
21
Rapid characterization of chemical constituents of Gansuibanxia decoction by UHPLC-FT-ICR-MS analysis. 61
31835125 2020
22
Aymé-Gripp Syndrome 61
32027476 2020
23
Echocardiographic abnormalities in children and adolescents living with human immunodeficiency virus on highly active antiretroviral treatment. 61
32022822 2020
24
Prognostic factors of EGFR-mutated metastatic adenocarcinoma of lung. 61
31846863 2020
25
Smartphone interfaced handheld echocardiography for focused assessment of ventricular function and structure in children: A pilot study. 61
31879998 2020
26
[Molecular diagnostics of cytological specimens]. 61
31932945 2020
27
Occurrence of right ventricular dysfunction immediately after pericardiocentesis. 61
31230096 2020
28
Significant cardiac disease complicating Graves' disease in previously healthy young adults. 61
31967967 2020
29
E-cigarette, or vaping, product use-associated lung injury in adolescents: a review of imaging features. 61
31897566 2020
30
A 61-Year-Old Woman With New Pericardial Effusion. 61
31968046 2020
31
Usefulness of Cardiac Magnetic Resonance for Recurrent Pericarditis. 61
31711636 2020
32
Outcomes of transvenous lead extraction in patients with lead perforation: A single-center experience. 61
31904110 2020
33
Massive Pericardial Effusion with Cardiac Tamponade. 61
30962021 2020
34
Nomogram construction for predicting survival of patients with non-small cell lung cancer with malignant pleural or pericardial effusion based on SEER analysis of 10,268 patients. 61
31897158 2020
35
Pericardial diseases in patients with cancer: contemporary prevalence, management and outcomes. 61
31980441 2020
36
Cardiofaciocutaneous syndrome with KRAS gene mutation presenting as chylopericardium. 61
31926049 2020
37
Secondary cardiac involvement in anti-SRP-antibody-positive myopathy: an 87-year-old woman with heart failure symptoms as the first clinical presentation. 61
31952503 2020
38
Distal Airway Aspirated Metallic Foreign Body, Case Report of Spontaneous Expectoration. 61
31910200 2020
39
Efficacy and safety of catheter ablation combined with left atrial appendage occlusion for nonvalvular atrial fibrillation: A systematic review and meta-analysis. 61
31721242 2020
40
Point-of-care ultrasound predictors for the diagnosis of tuberculosis in HIV-positive patients presenting to an emergency center. 61
31904699 2020
41
Intra-procedural monitoring protocol using routine transthoracic echocardiography with backup trans-oesophageal probe in transcatheter aortic valve replacement: a single centre experience. 61
30977790 2020
42
Heart failure enigma in young man: the acute onset of a frequently encountered condition with an unexpected cause. 61
31959653 2020
43
Fast growing angiosarcoma of the right atrium after radiofrequency catheter ablation: a missed diagnosis or misdiagnosis case report. 61
31906980 2020
44
Transcatheter closure of atrial septal defect in symptomatic children weighing ≤10 kg: Addressing unanswered issues from a decade of experience. 61
32030029 2020
45
Mycotic Coronary Aneurysms. 61
30686642 2020
46
Left atrial appendage closure after cryoballoon ablation in patients with atrial fibrillation. 61
32002565 2020
47
Etiology of Pericardial Effusion and Outcomes Post Pericardiocentesis in the Western Region of Saudi Arabia: A Single-center Experience. 61
31966943 2020
48
Management of Acute and Recurrent Pericarditis: JACC State-of-the-Art Review. 61
31918837 2020
49
Evaluation and Treatment of Cardiac Tamponade in a Pregnant Patient. 61
32015919 2020
50
[Pericardial Fenestration and Multidisciplinary Treatment to Improve the Prognosis of the Malignant Pericarditis Due to Lung Cancer]. 61
31956251 2020

Variations for Pericardial Effusion

ClinVar genetic disease variations for Pericardial Effusion:

6 ‎‎ ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 NLRP3 NM_001079821.2(NLRP3):c.1805A>G (p.Gln602Arg)SNV Likely pathogenic 374002 rs1057518827 1:247588550-247588550 1:247425248-247425248
2 SERPINA11 NM_001080451.2(SERPINA11):c.672C>A (p.Tyr224Ter)SNV Likely pathogenic 631492 14:94912913-94912913 14:94446576-94446576

Expression for Pericardial Effusion

Search GEO for disease gene expression data for Pericardial Effusion.

Pathways for Pericardial Effusion

GO Terms for Pericardial Effusion

Cellular components related to Pericardial Effusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.8 VEGFA TNFRSF1A SERPINA11 REN PVR NPPB
2 extracellular space GO:0005615 9.47 VEGFA TNFRSF1A SERPINA11 REN PVR NPPB

Biological processes related to Pericardial Effusion according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.7 VEGFA TNFRSF1A IL6
2 positive regulation of endothelial cell proliferation GO:0001938 9.69 VEGFA HIF1A FGF2
3 response to hypoxia GO:0001666 9.67 VEGFA NPPA HIF1A ADA
4 angiotensin maturation GO:0002003 9.56 REN ACE
5 cGMP biosynthetic process GO:0006182 9.55 NPPB NPPA
6 receptor guanylyl cyclase signaling pathway GO:0007168 9.54 NPPB NPPA
7 positive regulation of blood vessel endothelial cell migration GO:0043536 9.5 VEGFA HIF1A FGF2
8 negative regulation of lipid storage GO:0010888 9.49 IL6 CRP
9 neutrophil mediated immunity GO:0002446 9.48 IL6 ACE
10 positive regulation of T-helper 2 cell cytokine production GO:2000553 9.46 NLRP3 IL6
11 negative regulation of thymocyte apoptotic process GO:0070244 9.43 HIF1A ADA
12 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061419 9.4 VEGFA HIF1A
13 cytokine-mediated signaling pathway GO:0019221 9.35 VEGFA TNFRSF1A IL6 HIF1A FGF2
14 positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 9.33 VEGFA PIK3C2A FGF2
15 positive regulation of peptidyl-tyrosine autophosphorylation GO:1900086 9.26 VEGFA ACE
16 regulation of blood pressure GO:0008217 8.92 REN NPPB NPPA ACE

Molecular functions related to Pericardial Effusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone receptor binding GO:0051427 8.62 NPPB NPPA

Sources for Pericardial Effusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....