MCID: PRC010
MIFTS: 37

Pericardial Mesothelioma

Categories: Cancer diseases, Cardiovascular diseases

Aliases & Classifications for Pericardial Mesothelioma

MalaCards integrated aliases for Pericardial Mesothelioma:

Name: Pericardial Mesothelioma 12 15 73
Malignant Mesothelioma of Pericardium 12
Malignant Pericardial Mesothelioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6201
ICD10 33 C45.2

Summaries for Pericardial Mesothelioma

MalaCards based summary : Pericardial Mesothelioma, also known as malignant mesothelioma of pericardium, is related to benign mesothelioma and pericarditis. An important gene associated with Pericardial Mesothelioma is VIM (Vimentin), and among its related pathways/superpathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include heart, liver and bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Pericardial Mesothelioma

Diseases related to Pericardial Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 203)
# Related Disease Score Top Affiliating Genes
1 benign mesothelioma 30.4 HBA1 KRT7 PTGER4
2 pericarditis 10.4
3 endometrial mucinous adenocarcinoma 10.4 MUC1 VIM
4 clear cell meningioma 10.4 MUC1 VIM
5 myxopapillary ependymoma 10.4 MUC1 VIM
6 biphasic synovial sarcoma 10.4 MUC1 VIM
7 fibrous meningioma 10.4 MUC1 VIM
8 eccrine porocarcinoma 10.4 MUC1 VIM
9 chordoid meningioma 10.4 MUC1 VIM
10 constrictive pericarditis 10.3
11 rheumatoid lung disease 10.3 MUC1 SMUG1
12 regional odontodysplasia 10.3 KRT19 VIM
13 spindle cell rhabdomyosarcoma 10.3 MB MUC1
14 papillary adenoma 10.3 KRT7 VIM
15 adenomyoma 10.3 KRT7 MUC1
16 benign metastasizing leiomyoma 10.3 KRT7 VIM
17 corneal abscess 10.3 KRT19 KRT7
18 bowen's disease 10.3 KRT10 KRT7
19 cutaneous adenocystic carcinoma 10.3 KRT19 KRT7
20 bladder carcinoma in situ 10.3 KRT19 KRT7
21 papillary serous adenocarcinoma 10.3 KRT7 PTGER4
22 thymus adenocarcinoma 10.3 KRT7 PTGER4
23 splenic tuberculosis 10.3 KRT19 SMUG1
24 epithelioid leiomyosarcoma 10.3 ENO2 VIM
25 microcystic adenoma 10.3 ENO2 MUC1
26 astroblastoma 10.3 ENO2 VIM
27 epithelioid malignant peripheral nerve sheath tumor 10.3 ENO2 MUC1
28 filamentary keratitis 10.3 KRT10 MUC1 MUC16
29 reticulum cell sarcoma 10.3 MUC1 S100A1 VIM
30 sternum cancer 10.3 SMUG1 VIM
31 jejunal adenocarcinoma 10.3 KRT7 SMUG1
32 cecal benign neoplasm 10.3 KRT7 SMUG1
33 malignant peritoneal mesothelioma 10.3 MUC1 VIM
34 polymorphous low-grade adenocarcinoma 10.2 MUC1 S100A1 VIM
35 intrahepatic bile duct adenoma 10.2 KRT19 KRT7
36 spindle cell thymoma 10.2 MUC1 PTGER4
37 corpus luteum cyst 10.2 MUC16 SMUG1
38 endocrine gland cancer 10.2 KRT19 MUC1 SMUG1
39 aortitis 10.2 MPO SMUG1
40 anal gland adenocarcinoma 10.2 KRT19 KRT7
41 proliferating trichilemmal cyst 10.2 KRT19 KRT7
42 epulis 10.2 ENO2 VIM
43 malignant epithelial mesothelioma 10.2 PTGER4 THBD
44 pilomatrix carcinoma 10.2 ENO2 MUC1
45 cystic basal cell carcinoma 10.2 KRT7 PTGER4
46 hemopericardium 10.2
47 cardiac tamponade 10.2
48 pericardial effusion 10.2
49 anus basaloid carcinoma 10.2 KRT7 PTGER4
50 hidradenoma 10.2 KRT7 MUC1 VIM

Graphical network of the top 20 diseases related to Pericardial Mesothelioma:



Diseases related to Pericardial Mesothelioma

Symptoms & Phenotypes for Pericardial Mesothelioma

GenomeRNAi Phenotypes related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

26 (show all 26)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 10.13 ERF
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 10.13 ERF VIM
3 Increased shRNA abundance (Z-score > 2) GR00366-A-107 10.13 ERF
4 Increased shRNA abundance (Z-score > 2) GR00366-A-137 10.13 GFPT1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-146 10.13 ERF GFPT1 KRT19 VIM
6 Increased shRNA abundance (Z-score > 2) GR00366-A-169 10.13 KRT19
7 Increased shRNA abundance (Z-score > 2) GR00366-A-170 10.13 GFPT1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-176 10.13 VIM
9 Increased shRNA abundance (Z-score > 2) GR00366-A-177 10.13 KRT19 VIM
10 Increased shRNA abundance (Z-score > 2) GR00366-A-189 10.13 VIM
11 Increased shRNA abundance (Z-score > 2) GR00366-A-190 10.13 VIM
12 Increased shRNA abundance (Z-score > 2) GR00366-A-2 10.13 GFPT1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-29 10.13 VIM
14 Increased shRNA abundance (Z-score > 2) GR00366-A-3 10.13 GFPT1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-30 10.13 VIM
16 Increased shRNA abundance (Z-score > 2) GR00366-A-32 10.13 ERF
17 Increased shRNA abundance (Z-score > 2) GR00366-A-43 10.13 KRT19
18 Increased shRNA abundance (Z-score > 2) GR00366-A-46 10.13 GFPT1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-49 10.13 ERF
20 Increased shRNA abundance (Z-score > 2) GR00366-A-54 10.13 GFPT1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-63 10.13 VIM
22 Increased shRNA abundance (Z-score > 2) GR00366-A-73 10.13 ERF
23 Increased shRNA abundance (Z-score > 2) GR00366-A-76 10.13 GFPT1
24 Increased shRNA abundance (Z-score > 2) GR00366-A-82 10.13 ERF
25 Increased shRNA abundance (Z-score > 2) GR00366-A-85 10.13 VIM
26 Negative genetic interaction between PTEN-/- and PTEN+/+ GR00255-A-3 9.1 CD99 ENO2 KRT10 MPO SMUG1 THBD

MGI Mouse Phenotypes related to Pericardial Mesothelioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.36 ENO2 ERF FOXK1 KRT19 KRT7 MB

Drugs & Therapeutics for Pericardial Mesothelioma

Search Clinical Trials , NIH Clinical Center for Pericardial Mesothelioma

Genetic Tests for Pericardial Mesothelioma

Anatomical Context for Pericardial Mesothelioma

MalaCards organs/tissues related to Pericardial Mesothelioma:

41
Heart, Liver, Bone, Lung, Kidney, Pancreas, Thymus

Publications for Pericardial Mesothelioma

Articles related to Pericardial Mesothelioma:

(show top 50) (show all 124)
# Title Authors Year
1
Echocardiographic characteristics of primary malignant pericardial mesothelioma and outcomes analysis: a retrospective study. ( 29695235 )
2018
2
<sup>18</sup>F-fluorodeoxyglucose imaging of primary malignant pericardial mesothelioma with concurrent pericardial and pleural effusions and bone metastasis: A case report. ( 29805789 )
2018
3
The Antemortem Diagnosis of Primary Malignant Pericardial Mesothelioma: A Multidisciplinary Evaluation. ( 29709931 )
2018
4
Recurrence of Pericardial Mesothelioma Affecting the Myocardium after Pericardial Resection. ( 29792828 )
2018
5
Pericardial mesothelioma presenting as chronic constrictive pericarditis. A series of three cases from a single institution. ( 30303153 )
2018
6
Malignant pericardial mesothelioma : A systematic review of current practice. ( 28130567 )
2018
7
Localized primary malignant pericardial mesothelioma. ( 30450660 )
2018
8
Pericardial mesothelioma presenting as a suspected ST-elevation myocardial infarction. ( 28343785 )
2017
9
A second case of pericardial mesothelioma mimicking systemic lupus erythematosus in the literature in over 30 years: a case report. ( 28351431 )
2017
10
Primary pericardial mesothelioma and asbestos exposure: a rare fatal disease. ( 28500034 )
2017
11
Primary pericardial mesothelioma in a 48-year-old patient. ( 29171839 )
2017
12
Pericardial mesothelioma. ( 27318362 )
2016
13
F-18 FDG PET/CT images of a rare primer cardiac tumour: Primary Pericardial Mesothelioma. ( 27515105 )
2016
14
Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report. ( 27347127 )
2016
15
Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report. ( 27900083 )
2016
16
Sarcomatoid Type Primary Pericardial Mesothelioma with a Long-term Survival after the Onset of Cardiac Tamponade. ( 27803412 )
2016
17
Pericardial Effusion due to Primary Malignant Pericardial Mesothelioma: A Common Finding but an Uncommon Cause. ( 28003826 )
2016
18
Primary pericardial mesothelioma presenting as multiple pericardial masses on CT. ( 30364446 )
2016
19
Pericardial Mesothelioma in a Yellow-naped Amazon Parrot ( Amazona auropalliata ). ( 25867668 )
2015
20
Successful palliation for an aged patient with primary pericardial mesothelioma. ( 26376726 )
2015
21
Endobronchial ultrasound-guided transbronchial needle aspiration in a patient with pericardial mesothelioma. ( 25742892 )
2015
22
A rare cause of heart failure with preserved ejection fraction: primary pericardial mesothelioma masquerading as pericardial constriction. ( 24654246 )
2014
23
Primary malignant pericardial mesothelioma-a rare cause of superior vena cava thrombosis and constrictive pericarditis. ( 25590007 )
2014
24
A rare case of primary malignant pericardial mesothelioma. ( 25250196 )
2014
25
Primary pericardial mesothelioma: A rare cause of constrictive pericarditis. ( 24887935 )
2013
26
Three-year survival after surgery for primary malignant pericardial mesothelioma: report of a case. ( 23408086 )
2013
27
Mixed form of pericardial mesothelioma with osseous differentiation in a dog. ( 23578582 )
2013
28
Primary pericardial mesothelioma: a rare entity. ( 23840993 )
2013
29
Cardiac MRI findings in a dog with a diffuse pericardial mesothelioma and pericardial effusion. ( 24051256 )
2013
30
Primary pericardial mesothelioma in a 19-year-old presenting as pericarditis. ( 23353042 )
2013
31
Primary sarcomatoid malignant pericardial mesothelioma. ( 23291695 )
2013
32
Fluorine-18 fluoro-2-deoxyglucose positron emission tomography/computed tomography in a case of suspected primary pericardial mesothelioma. ( 23919083 )
2012
33
Unexpected malignant pericardial mesothelioma presenting as pericardial constriction. ( 23094904 )
2012
34
Primary malignant pericardial mesothelioma presenting as acute pericarditis. ( 22509441 )
2012
35
Primary pericardial mesothelioma unique case and literature review. ( 22740748 )
2012
36
A case report of an extremely rare and aggressive tumor: primary malignant pericardial mesothelioma. ( 22826778 )
2012
37
A case of primary pericardial mesothelioma detected by 18F-FDG PET/CT. ( 22475912 )
2012
38
False aneurysm of ascending aorta due to pericardial mesothelioma. ( 22593561 )
2012
39
Pericardial mesothelioma and asbestos exposure. ( 21156353 )
2011
40
Malignant pericardial mesothelioma. ( 20643560 )
2011
41
A case of malignant pericardial mesothelioma with constrictive pericarditis physiology misdiagnosed as pericardial metastatic cancer. ( 21779289 )
2011
42
Primary malignant pericardial mesothelioma presenting as effusive-constrictive pericarditis. ( 21828406 )
2011
43
Primary pericardial mesothelioma in an asbestos-exposed patient with previous heart surgery. ( 20530447 )
2010
44
Primary malignant pericardial mesothelioma mimicking pericardial metastasis from adenocarcinoma. ( 21102264 )
2010
45
Malignant pericardial mesothelioma following thoracal radiotherapy; dissemination from pericardium to pleura. ( 21038142 )
2010
46
Surprising finding of a primary pericardial mesothelioma. ( 20339921 )
2010
47
Surgical experience of pericardial mesothelioma presenting as constrictive pericarditis. ( 30524596 )
2010
48
Malignant pericardial mesothelioma with response to chemotherapy. ( 19861909 )
2009
49
Fatal hemopericardial tamponade due to primary pericardial mesothelioma: a case report. ( 20003222 )
2009
50
Primary malignant pericardial mesothelioma - a rare cause of pericardial effusion and consecutive constrictive pericarditis: a case report. ( 19918293 )
2009

Variations for Pericardial Mesothelioma

Expression for Pericardial Mesothelioma

Search GEO for disease gene expression data for Pericardial Mesothelioma.

Pathways for Pericardial Mesothelioma

Pathways related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.51 KRT10 KRT19 KRT7 MUC1 VIM
2
Show member pathways
11.37 KRT19 KRT7 VIM
3 9.86 HBA1 MB

GO Terms for Pericardial Mesothelioma

Cellular components related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 ENO2 HBA1 KRT10 MPO MSLN MUC1
2 extracellular exosome GO:0070062 9.36 ENO2 GFPT1 HBA1 KRT10 KRT19 KRT7
3 apicolateral plasma membrane GO:0016327 9.26 KRT19 THBD
4 intermediate filament GO:0005882 9.26 KRT10 KRT19 KRT7 VIM

Biological processes related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.13 KRT10 KRT19 KRT7
2 oxygen transport GO:0015671 8.62 HBA1 MB

Molecular functions related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxygen carrier activity GO:0005344 8.62 HBA1 MB

Sources for Pericardial Mesothelioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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