MCID: PRC010
MIFTS: 36

Pericardial Mesothelioma

Categories: Cancer diseases, Cardiovascular diseases

Aliases & Classifications for Pericardial Mesothelioma

MalaCards integrated aliases for Pericardial Mesothelioma:

Name: Pericardial Mesothelioma 12 15 73
Malignant Mesothelioma of Pericardium 12
Malignant Pericardial Mesothelioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6201
ICD10 33 C45.2
SNOMED-CT 68 109383000 187885008

Summaries for Pericardial Mesothelioma

MalaCards based summary : Pericardial Mesothelioma, also known as malignant mesothelioma of pericardium, is related to regional odontodysplasia and malignant peritoneal mesothelioma. An important gene associated with Pericardial Mesothelioma is MUC1 (Mucin 1, Cell Surface Associated), and among its related pathways/superpathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include heart, liver and brain, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Pericardial Mesothelioma

Diseases related to Pericardial Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 199)
# Related Disease Score Top Affiliating Genes
1 regional odontodysplasia 11.0 KRT19 VIM
2 malignant peritoneal mesothelioma 10.9 MUC1 VIM
3 splenic tuberculosis 10.9 KRT19 SMUG1
4 filamentary keratitis 10.9 KRT10 MUC1 MUC16
5 corpus luteum cyst 10.9 MUC16 SMUG1
6 fibrous meningioma 10.9 MUC1 VIM
7 sternum cancer 10.9 SMUG1 VIM
8 solid adenocarcinoma with mucin production 10.9 KRT7 MUC1
9 chordoid meningioma 10.9 MUC1 VIM
10 basal cell carcinoma, infundibulocystic 10.9 KRT10 PTGER4
11 syringocystadenoma papilliferum 10.8 MUC1 VIM
12 reticulum cell sarcoma 10.8 MUC1 S100A1 VIM
13 eccrine porocarcinoma 10.8 MUC1 VIM
14 intrahepatic bile duct adenoma 10.8 KRT19 KRT7
15 anal gland adenocarcinoma 10.8 KRT19 KRT7
16 proliferating trichilemmal cyst 10.8 KRT19 KRT7
17 polymorphous low-grade adenocarcinoma 10.8 MUC1 S100A1 VIM
18 endometrial mucinous adenocarcinoma 10.8 MUC1 VIM
19 malignant epithelial mesothelioma 10.8 PTGER4 THBD
20 pilomatrix carcinoma 10.8 ENO2 MUC1
21 anus adenocarcinoma 10.8 KRT19 KRT7
22 biphasic synovial sarcoma 10.8 MUC1 VIM
23 cystic basal cell carcinoma 10.8 KRT7 PTGER4
24 anus basaloid carcinoma 10.7 KRT7 PTGER4
25 intracranial cysts 10.7 ENO2 MUC1
26 bile duct mucoepidermoid carcinoma 10.7 KRT7 MUC1
27 malignant peripheral nerve sheath tumor 10.7 MUC1 S100A1 VIM
28 renal pelvis adenocarcinoma 10.7 KRT19 KRT7
29 mast-cell sarcoma 10.7 MPO VIM
30 parachordoma 10.7 KRT7 MUC1 VIM
31 sinonasal undifferentiated carcinoma 10.7 ENO2 MUC1
32 malignant mixed mullerian tumor 10.7 KRT7 MUC1 VIM
33 bednar tumor 10.7 ENO2 VIM
34 primitive neuroectodermal tumor of the cervix uteri 10.7 ENO2 VIM
35 monophasic synovial sarcoma 10.7 KRT7 MUC1 VIM
36 spiradenoma 10.7 KRT7 MUC1 VIM
37 hidradenoma 10.7 KRT7 MUC1 VIM
38 mucinous cystadenocarcinoma 10.7 KRT7 MUC1 VIM
39 malignant syringoma 10.7 KRT7 PTGER4
40 cutaneous adenocystic carcinoma 10.7 KRT19 KRT7
41 cavernous hemangioma 10.7 MB MUC1 VIM
42 dermoid cyst 10.7 KRT7 MUC1 VIM
43 spindle cell sarcoma 10.7 KRT7 MUC1 VIM
44 biliary papillomatosis 10.7 KRT19 KRT7 MUC1
45 malignant spiradenoma 10.7 KRT7 SMUG1
46 lipoadenoma 10.6 KRT19 KRT7 MUC1
47 spindle cell rhabdomyosarcoma 10.6 MB MUC1
48 endodermal sinus tumor 10.6 KRT7 MUC16 VIM
49 papillary adenoma 10.6 KRT7 VIM
50 malignant ectomesenchymoma 10.6 ENO2 S100A1

Graphical network of the top 20 diseases related to Pericardial Mesothelioma:



Diseases related to Pericardial Mesothelioma

Symptoms & Phenotypes for Pericardial Mesothelioma

GenomeRNAi Phenotypes related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

26 (show all 27)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 10.15 ERF
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 10.15 VIM ERF
3 Increased shRNA abundance (Z-score > 2) GR00366-A-107 10.15 ERF
4 Increased shRNA abundance (Z-score > 2) GR00366-A-116 10.15 GFPT1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-137 10.15 GFPT1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-146 10.15 KRT19 VIM ERF GFPT1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-169 10.15 KRT19
8 Increased shRNA abundance (Z-score > 2) GR00366-A-170 10.15 GFPT1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-176 10.15 VIM
10 Increased shRNA abundance (Z-score > 2) GR00366-A-177 10.15 KRT19 VIM
11 Increased shRNA abundance (Z-score > 2) GR00366-A-189 10.15 VIM
12 Increased shRNA abundance (Z-score > 2) GR00366-A-190 10.15 VIM
13 Increased shRNA abundance (Z-score > 2) GR00366-A-2 10.15 GFPT1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-29 10.15 VIM
15 Increased shRNA abundance (Z-score > 2) GR00366-A-3 10.15 GFPT1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-30 10.15 VIM
17 Increased shRNA abundance (Z-score > 2) GR00366-A-32 10.15 ERF
18 Increased shRNA abundance (Z-score > 2) GR00366-A-43 10.15 KRT19
19 Increased shRNA abundance (Z-score > 2) GR00366-A-46 10.15 GFPT1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-49 10.15 ERF
21 Increased shRNA abundance (Z-score > 2) GR00366-A-54 10.15 GFPT1
22 Increased shRNA abundance (Z-score > 2) GR00366-A-63 10.15 VIM
23 Increased shRNA abundance (Z-score > 2) GR00366-A-73 10.15 ERF
24 Increased shRNA abundance (Z-score > 2) GR00366-A-76 10.15 GFPT1
25 Increased shRNA abundance (Z-score > 2) GR00366-A-82 10.15 ERF
26 Increased shRNA abundance (Z-score > 2) GR00366-A-85 10.15 VIM
27 Negative genetic interaction between PTEN-/- and PTEN+/+ GR00255-A-3 9.1 MPO SMUG1 THBD CD99 ENO2 KRT10

MGI Mouse Phenotypes related to Pericardial Mesothelioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.36 ENO2 ERF FOXK1 KRT19 KRT7 MB

Drugs & Therapeutics for Pericardial Mesothelioma

Search Clinical Trials , NIH Clinical Center for Pericardial Mesothelioma

Genetic Tests for Pericardial Mesothelioma

Anatomical Context for Pericardial Mesothelioma

MalaCards organs/tissues related to Pericardial Mesothelioma:

41
Heart, Liver, Brain, Bone

Publications for Pericardial Mesothelioma

Articles related to Pericardial Mesothelioma:

(show top 50) (show all 117)
# Title Authors Year
1
Echocardiographic characteristics of primary malignant pericardial mesothelioma and outcomes analysis: a retrospective study. ( 29695235 )
2018
2
<sup>18</sup>F-fluorodeoxyglucose imaging of primary malignant pericardial mesothelioma with concurrent pericardial and pleural effusions and bone metastasis: A case report. ( 29805789 )
2018
3
The Antemortem Diagnosis of Primary Malignant Pericardial Mesothelioma: A Multidisciplinary Evaluation. ( 29709931 )
2018
4
Recurrence of Pericardial Mesothelioma Affecting the Myocardium after Pericardial Resection. ( 29792828 )
2018
5
Pericardial mesothelioma presenting as a suspected ST-elevation myocardial infarction. ( 28343785 )
2017
6
A second case of pericardial mesothelioma mimicking systemic lupus erythematosus in the literature in over 30 years: a case report. ( 28351431 )
2017
7
Primary pericardial mesothelioma and asbestos exposure: a rare fatal disease. ( 28500034 )
2017
8
Malignant pericardial mesothelioma : AA systematic review of current practice. ( 28130567 )
2017
9
Primary pericardial mesothelioma in a 48-year-old patient. ( 29171839 )
2017
10
Pericardial mesothelioma. ( 27318362 )
2016
11
F-18 FDG PET/CT images of a rare primer cardiac tumour: Primary Pericardial Mesothelioma. ( 27515105 )
2016
12
Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report. ( 27347127 )
2016
13
Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report. ( 27900083 )
2016
14
Sarcomatoid Type Primary Pericardial Mesothelioma with a Long-term Survival after the Onset of Cardiac Tamponade. ( 27803412 )
2016
15
Pericardial Effusion due to Primary Malignant Pericardial Mesothelioma: A Common Finding but an Uncommon Cause. ( 28003826 )
2016
16
Pericardial Mesothelioma in a Yellow-naped Amazon Parrot ( Amazona auropalliata ). ( 25867668 )
2015
17
Successful palliation for an aged patient with primary pericardial mesothelioma. ( 26376726 )
2015
18
Endobronchial ultrasound-guided transbronchial needle aspiration in a patient with pericardial mesothelioma. ( 25742892 )
2015
19
A rare cause of heart failure with preserved ejection fraction: primary pericardial mesothelioma masquerading as pericardial constriction. ( 24654246 )
2014
20
Primary malignant pericardial mesothelioma-a rare cause of superior vena cava thrombosis and constrictive pericarditis. ( 25590007 )
2014
21
A rare case of primary malignant pericardial mesothelioma. ( 25250196 )
2014
22
Primary pericardial mesothelioma: A rare cause of constrictive pericarditis. ( 24887935 )
2013
23
Three-year survival after surgery for primary malignant pericardial mesothelioma: report of a case. ( 23408086 )
2013
24
Mixed form of pericardial mesothelioma with osseous differentiation in a dog. ( 23578582 )
2013
25
Primary pericardial mesothelioma: a rare entity. ( 23840993 )
2013
26
Cardiac MRI findings in a dog with a diffuse pericardial mesothelioma and pericardial effusion. ( 24051256 )
2013
27
Primary pericardial mesothelioma in a 19-year-old presenting as pericarditis. ( 23353042 )
2013
28
Primary sarcomatoid malignant pericardial mesothelioma. ( 23291695 )
2013
29
Fluorine-18 fluoro-2-deoxyglucose positron emission tomography/computed tomography in a case of suspected primary pericardial mesothelioma. ( 23919083 )
2012
30
Unexpected malignant pericardial mesothelioma presenting as pericardial constriction. ( 23094904 )
2012
31
Primary malignant pericardial mesothelioma presenting as acute pericarditis. ( 22509441 )
2012
32
Primary pericardial mesothelioma unique case and literature review. ( 22740748 )
2012
33
A case report of an extremely rare and aggressive tumor: primary malignant pericardial mesothelioma. ( 22826778 )
2012
34
A case of primary pericardial mesothelioma detected by 18F-FDG PET/CT. ( 22475912 )
2012
35
False aneurysm of ascending aorta due to pericardial mesothelioma. ( 22593561 )
2012
36
Pericardial mesothelioma and asbestos exposure. ( 21156353 )
2011
37
Malignant pericardial mesothelioma. ( 20643560 )
2011
38
A case of malignant pericardial mesothelioma with constrictive pericarditis physiology misdiagnosed as pericardial metastatic cancer. ( 21779289 )
2011
39
Primary malignant pericardial mesothelioma presenting as effusive-constrictive pericarditis. ( 21828406 )
2011
40
Primary pericardial mesothelioma in an asbestos-exposed patient with previous heart surgery. ( 20530447 )
2010
41
Primary malignant pericardial mesothelioma mimicking pericardial metastasis from adenocarcinoma. ( 21102264 )
2010
42
Malignant pericardial mesothelioma following thoracal radiotherapy; dissemination from pericardium to pleura. ( 21038142 )
2010
43
Surprising finding of a primary pericardial mesothelioma. ( 20339921 )
2010
44
Malignant pericardial mesothelioma with response to chemotherapy. ( 19861909 )
2009
45
Fatal hemopericardial tamponade due to primary pericardial mesothelioma: a case report. ( 20003222 )
2009
46
Primary malignant pericardial mesothelioma - a rare cause of pericardial effusion and consecutive constrictive pericarditis: a case report. ( 19918293 )
2009
47
Primary Pericardial Mesothelioma: Report of a Patient and Literature Review. ( 20740175 )
2009
48
Primary malignant pericardial mesothelioma presenting as pericardial constriction. ( 19131929 )
2008
49
Primary pericardial mesothelioma. ( 17936406 )
2008
50
Pericardial mesothelioma in a Bengal tiger (Panthera tigris). ( 18432108 )
2008

Variations for Pericardial Mesothelioma

Expression for Pericardial Mesothelioma

Search GEO for disease gene expression data for Pericardial Mesothelioma.

Pathways for Pericardial Mesothelioma

Pathways related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.51 KRT10 KRT19 KRT7 MUC1 VIM
2
Show member pathways
11.37 KRT19 KRT7 VIM
3 9.86 HBA1 MB

GO Terms for Pericardial Mesothelioma

Cellular components related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 ENO2 HBA1 KRT10 MPO MSLN MUC1
2 extracellular exosome GO:0070062 9.36 ENO2 GFPT1 HBA1 KRT10 KRT19 KRT7
3 intermediate filament GO:0005882 9.26 KRT10 KRT19 KRT7 VIM

Biological processes related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.13 KRT10 KRT19 KRT7
2 oxygen transport GO:0015671 8.62 HBA1 MB

Molecular functions related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxygen carrier activity GO:0005344 8.62 HBA1 MB

Sources for Pericardial Mesothelioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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