Aliases & Classifications for Pericarditis

MalaCards integrated aliases for Pericarditis:

Name: Pericarditis 12 29 55 44 15 63 73

Classifications:



External Ids:

Disease Ontology 12 DOID:1787
MeSH 44 D010493
NCIt 50 C34915
SNOMED-CT 68 3238004
ICD10 33 I32 I32.8
UMLS 73 C0031046

Summaries for Pericarditis

PubMed Health : 63 About pericarditis: Pericarditis (PER-ih-kar-DI-tis) is a condition in which the membrane, or sac, around your heart is inflamed. This sac is called the pericardium (per-ih-KAR-de-um).The pericardium holds the heart in place and helps it work properly. The sac is made of two thin layers of tissue that enclose your heart. Between the two layers is a small amount of fluid. This fluid keeps the layers from rubbing against each other and causing friction.

MalaCards based summary : Pericarditis is related to idiopathic recurrent pericarditis and constrictive pericarditis, and has symptoms including chest pain An important gene associated with Pericarditis is PRG4 (Proteoglycan 4), and among its related pathways/superpathways are Akt Signaling and Toll-like Receptor Signaling Pathway. The drugs Colchicine and Coal tar have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and kidney, and related phenotypes are cardiovascular system and hematopoietic system

Disease Ontology : 12 A pericardium disease that is characterized by an inflammation of the pericardium and has symptom chest pain.

Wikipedia : 76 Pericarditis is inflammation of the pericardium (the fibrous sac surrounding the heart). Symptoms... more...

Related Diseases for Pericarditis

Diseases related to Pericarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 499)
# Related Disease Score Top Affiliating Genes
1 idiopathic recurrent pericarditis 34.4 MEFV TNFRSF1A
2 constrictive pericarditis 34.3 ADA NPPB PRG4
3 systemic onset juvenile idiopathic arthritis 31.3 IL1B MEFV TNF
4 cardiac tamponade 31.1 NPPB TNFRSF1A
5 arthropathy 30.6 CRP PRG4 TNF
6 pleural empyema 30.5 ADA CRP
7 endocarditis 30.4 CRP IL6 TNF
8 hyper-igd syndrome 30.3 CRP TNFRSF1A
9 myocarditis 30.2 IL6 NPPB TNF
10 periodic fever, familial, autosomal dominant 30.1 MEFV TNF TNFRSF1A
11 pericardial effusion 30.0 ADA CRP IL6 NPPB TNFRSF1A
12 streptococcal toxic-shock syndrome 29.9 IL6 TNF
13 vasculitis 29.9 CRP MEFV TNF
14 infective endocarditis 29.9 CRP IL6 TNF
15 angina pectoris 29.9 CRP IL6
16 listeria meningitis 29.8 ADA TNF
17 takayasu arteritis 29.7 CRP IL6 TNF
18 cardiogenic shock 29.7 CRP IL6 NPPB
19 brucellosis 29.6 CRP IL6 MEFV TNF
20 haemophilus influenzae 29.5 IL1B TNF
21 acute myocardial infarction 29.5 CRP NPPB TNNT2
22 wegener granulomatosis 29.4 CRP IL6 TNF
23 pneumonia 29.4 CRP IL1B IL6 TNF
24 pleurisy 29.2 ADA CRP MEFV TNF
25 colitis 29.0 IL1B IL6 TNF
26 laryngitis 29.0 IL1B IL6 TNF
27 crohn's disease 29.0 CRP IL1B IL6 TNF
28 coronary artery anomaly 29.0 CRP IL6 NPPB TNNT2
29 toxic shock syndrome 28.9 IL1B IL6 TNF
30 graft-versus-host disease 28.9 IL1B IL6 TNF
31 rheumatoid arthritis 28.9 CRP IL1B IL6 TNF TNFRSF1A
32 pulmonary disease, chronic obstructive 28.8 CRP IL6 NPPB TNF
33 ulcerative colitis 28.7 CRP IL1B IL6 TNF
34 familial mediterranean fever 28.5 CRP IL1B MEFV TNF TNFRSF1A
35 leptospirosis 28.5 CRP IL1B IL6 TNF
36 lyme disease 28.5 CRP IL1B IL6 TNF
37 juvenile rheumatoid arthritis 28.5 CRP IL1B IL6 TNF
38 multiple sclerosis 28.4 IL1B IL6 TNF TNFRSF1A
39 adult-onset still's disease 28.3 CRP IL1B IL6 MEFV TNF
40 psoriasis 28.1 IL1B IL6 TNF TRAF3IP2
41 meningitis 27.9 ADA CRP IL1B IL6 IRAK4 TNF
42 myocardial infarction 27.8 CRP IL1B IL6 NPPB TNF TNNT2
43 peritonitis 27.7 ADA CRP IL1B IL6 MEFV TNF
44 psoriatic arthritis 27.4 CRP IL1B IL6 TNF TNFRSF1A TRAF3IP2
45 arteries, anomalies of 27.2 CRP IL1B IL6 NPPB TNF TNNT2
46 heart disease 27.2 CRP IL1B IL6 NPPB TNF TNNT2
47 dilated cardiomyopathy 26.8 CRP IL1B IL6 NPPB TNF TNNT2
48 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 12.5
49 histoplasmosis pericarditis 12.1
50 chronic rheumatic pericarditis 12.0

Graphical network of the top 20 diseases related to Pericarditis:



Diseases related to Pericarditis

Symptoms & Phenotypes for Pericarditis

Symptoms:

12
  • chest pain

MGI Mouse Phenotypes related to Pericarditis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.86 TNF TNFRSF1A ADA TNNT2 CRP TRAF3IP2
2 hematopoietic system MP:0005397 9.81 TNF TNFRSF1A ADA TRAF3IP2 HRH4 IL1B
3 homeostasis/metabolism MP:0005376 9.7 TNFRSF1A ADA TNNT2 CRP TRAF3IP2 HRH4
4 immune system MP:0005387 9.32 TNFRSF1A ADA CRP TRAF3IP2 HRH4 IL1B

Drugs & Therapeutics for Pericarditis

PubMedHealth treatment related to Pericarditis: 63

Most cases of pericarditis are mild; they clear up on their own or with rest and simple treatment. Other times, more intense treatment is needed to prevent complications. Treatment may include medicines and, less often, procedures or surgery.The goals of treatment include:Reducing pain and inflammationTreating the underlying cause, if it's knownChecking for complications

Drugs for Pericarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 124)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Colchicine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 64-86-8 6167 2833
2
Coal tar Approved Phase 4,Phase 3 8007-45-2
3
Menthol Approved Phase 4,Not Applicable 2216-51-5 16666
4
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
5 Anti-Bacterial Agents Phase 4
6 Antibiotics, Antitubercular Phase 4
7 Anti-Infective Agents Phase 4,Phase 1,Phase 2,Not Applicable
8 Antitubercular Agents Phase 4
9 Analgesics Phase 4
10 Fibrinolytic Agents Phase 4,Phase 3
11 Analgesics, Non-Narcotic Phase 4
12 Peripheral Nervous System Agents Phase 4,Phase 3,Not Applicable
13 Platelet Aggregation Inhibitors Phase 4,Phase 3
14 Interleukin 1 Receptor Antagonist Protein Phase 4,Phase 2
15 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
16 Anti-Inflammatory Agents, Non-Steroidal Phase 4
17 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
18 Antimitotic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
19 Cyclooxygenase Inhibitors Phase 4
20 Antipyretics Phase 4
21
Abciximab Approved Phase 3 143653-53-6
22
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
23
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
24
Reteplase Approved, Investigational Phase 3 133652-38-7 65820
25 Prednisolone acetate Phase 3
26 glucocorticoids Phase 3,Phase 2,Not Applicable
27 Methylprednisolone acetate Phase 3
28 Methylprednisolone Hemisuccinate Phase 3
29 Gastrointestinal Agents Phase 3
30 Neuroprotective Agents Phase 3
31 Tissue Plasminogen Activator Phase 3
32 Hormone Antagonists Phase 3,Phase 2,Not Applicable
33 Hormones Phase 3,Phase 2,Not Applicable
34 Vaccines Phase 3
35 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Not Applicable
36 Anti-Arrhythmia Agents Phase 3
37 Immunoglobulin Fab Fragments Phase 3
38 Antibodies Phase 3,Phase 1,Phase 2
39 Immunoglobulins Phase 3,Phase 1,Phase 2
40 Antibodies, Monoclonal Phase 3,Phase 1,Phase 2
41 Plasminogen Phase 3
42 Anticoagulants Phase 3,Not Applicable
43 Prednisolone hemisuccinate Phase 3
44 Prednisolone phosphate Phase 3
45 Antiemetics Phase 3
46 Protective Agents Phase 3,Phase 1,Phase 2
47 Autonomic Agents Phase 3,Not Applicable
48 Antineoplastic Agents, Hormonal Phase 3,Phase 2
49
Abatacept Approved Phase 2 332348-12-6 10237
50
Eplerenone Approved Phase 2 107724-20-9 150310 443872

Interventional clinical trials:

(show top 50) (show all 85)
# Name Status NCT ID Phase Drugs
1 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
2 AnakInRa for Treatment of Recurrent Idiopathic Pericarditis (AIRTRIP) Completed NCT02219828 Phase 4 Anakinra;Placebo
3 Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment. Completed NCT00235079 Phase 4 Colchicine;Placebo
4 Anti-inflammatory Effects of Colchicine in PCI Recruiting NCT01709981 Phase 4 Colchicine;Placebo
5 Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy Recruiting NCT03463317 Phase 4 Acetylsalicylic acid;Clopidogrel;Dabigatran;Rivaroxaban;Apixaban;Edoxaban;Phenprocoumon;Warfarin
6 NAVISTAR® THERMOCOOL® Catheter Post Approval Registry Active, not recruiting NCT00964392 Phase 4
7 Benign Acute Pericarditis: Brief Versus Longer Treatment Using Aspirin Terminated NCT00946907 Phase 4 Aspirin;placebo
8 Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences Completed NCT00128453 Phase 3 Colchicine (for 3 months);Placebo
9 Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode) Completed NCT00128414 Phase 3 Colchicine (for 6 months);Placebo
10 A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis Completed NCT00810849 Phase 3 Prednisolone
11 Study of Colchicine to Prevent the Postpericardiotomy Syndrome Completed NCT00128427 Phase 3 Colchicine (for 1 month)
12 SMART-SF Radiofrequency Ablation Safety Study Completed NCT02359890 Phase 3
13 THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation Completed NCT01385202 Phase 3
14 NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation Completed NCT00116428 Phase 3 Antiarrhythmic drug
15 THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation CONTINUED ACCESS Completed NCT01639495 Phase 3
16 A Trial to Evaluate Immunogenicity and Safety of Three Consecutive Production Lots of IMVAMUNE® (MVA-BN®) Smallpox Vaccine in Healthy, Vaccinia-naïve Subjects Completed NCT01144637 Phase 3
17 A Study of Abciximab and Reteplase When Administered Prior to Catherization After a Myocardial Infarction (Finesse) Completed NCT00046228 Phase 3 abciximab placebo; reteplase placebo, abciximab, abciximab;Abciximab; reteplase; abciximab placebo; abciximab;abciximab; reteplase placebo; abciximab placebo; abciximab;abciximab placebo; reteplase placebo, abciximab, abciximab;abciximab; reteplase placebo; abciximab placebo; abciximab;Abciximab; reteplase; abciximab placebo; abciximab
18 IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion Recruiting NCT02673879 Phase 3
19 Review of the Safety and Effectiveness of the THERMOCOOL SMARTTOUCH® SF Catheter Evaluated for Treating Symptomatic PersistenT AF (PRECEPT) Active, not recruiting NCT02817776 Phase 3
20 Myocardial Screening in Fetuses With Congenital Cytomegalovirus (CMV) Infection Not yet recruiting NCT02787382 Phase 3
21 Colchicine in Postoperative Fontan Patients Not yet recruiting NCT03575572 Phase 2, Phase 3 Colchicine
22 NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation- Treatment Use Study Terminated NCT00721149 Phase 3
23 A Randomized Comparison of Radiation Therapy Techniques in the Management of Node Positive Breast Cancer Completed NCT00581256 Phase 1, Phase 2
24 Abatacept in the Treatment and Prevention of Active Systemic Lupus Erythematosus (SLE) Flares in Combination With Prednisone Completed NCT00119678 Phase 2 Abatacept;Placebo;Prednisone;Abatacept
25 Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response Completed NCT02363725 Phase 2 Colchimax®;Conventional treatment
26 Overcoming Membrane Transporters to Improve CNS Drug Delivery - Improving Brain Antioxidants After Traumatic Brain Injury Completed NCT01322009 Phase 1, Phase 2 Probenecid and N-acetyl cysteine;Placebo
27 Effect of Green Tea on Treatment of Lupus Completed NCT02875691 Phase 2
28 REVOLUTION (WFCC-133) - Treatment of Paroxysmal Atrial Fibrillation Completed NCT01353586 Phase 2
29 A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee Completed NCT00565812 Phase 2 SD-6010;SD-6010;Placebo
30 Treatment of Acute Pericarditis With Anakinra Recruiting NCT03224585 Phase 2 Anakinra;Placebo
31 Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer Active, not recruiting NCT00750269 Phase 1, Phase 2
32 Ipilimumab With or Without Talimogene Laherparepvec in Unresected Melanoma Active, not recruiting NCT01740297 Phase 1, Phase 2 Talimogene laherparepvec;Ipilimumab
33 Chinese Medicine on Deferring Dialysis Initiation Enrolling by invitation NCT02194946 Phase 1, Phase 2 CM therapies;CKD-related management
34 Stereotactic Boost for Locally Advanced Non-Small Cell Lung Cancer Terminated NCT01222572 Phase 1, Phase 2 Etoposide;Cisplatin
35 Hypofractionated Proton Beam Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With Stage II-III Non-Small Cell Lung Cancer Completed NCT02172846 Phase 1 Paclitaxel;Carboplatin
36 Septal Shift for the Diagnosis of COnstrictive Pericarditis: The Impact of Inspiratory Effort Quantification on Deep Breathing Manoeuvres Unknown status NCT02685371
37 Noise, a Risk for Heart in Airplane Pilots Unknown status NCT01063582
38 Safety of Early Discharge Following Low Risk Myocardial Infarction Unknown status NCT01868256 Not Applicable
39 Transient ECG Changes in Patients With Acute Biliary Disease Unknown status NCT01706068
40 ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician? Completed NCT01041339
41 Apolipoprotein CIII Reduction Via Colchicine Completed NCT02083510 Early Phase 1 Colchicine
42 Epipericardial Fat Necrosis: A Misdiagnosed Condition Completed NCT01903980
43 Safety Surveillance Study of ACAM2000® Vaccinia Vaccine Completed NCT00927719
44 Evaluation of Myocardial Iron Deposition in Patients of Heart Failure Using T2* MR Imaging Completed NCT02527330
45 Detection of Enterovirus RNA in Atheromatous Lesions Completed NCT00674531 Not Applicable
46 Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 7.5 Years Follow-up Completed NCT01667068
47 Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 5 Years Follow-up Completed NCT01196273
48 Cardiomyopathy Following Stem Cell Transplantation Completed NCT00352209
49 Irrigated Ablation System Evaluation for Atrial Fibrillation (AF) Completed NCT01056328 Not Applicable
50 Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer Completed NCT00960999 Not Applicable

Search NIH Clinical Center for Pericarditis

Cochrane evidence based reviews: pericarditis

Genetic Tests for Pericarditis

Genetic tests related to Pericarditis:

# Genetic test Affiliating Genes
1 Pericarditis 29

Anatomical Context for Pericarditis

MalaCards organs/tissues related to Pericarditis:

41
Heart, Lung, Kidney, Liver, Brain, Lymph Node, Bone

Publications for Pericarditis

Articles related to Pericarditis:

(show top 50) (show all 1361)
# Title Authors Year
1
Acute pericarditis following second-generation cryoballoon ablation for atrial fibrillation. ( 29445985 )
2018
2
Case report of an unusual combination of purulent pericarditis and false aneurysm of the ascending aorta. ( 29378612 )
2018
3
Purulent pericarditis, an unusual complication of pneumococcal pneumonia: a case report. ( 29322942 )
2018
4
Undiagnosed Chilaiditi syndrome presenting with pericarditis in a patient with congenital anomalies. ( 29970610 )
2018
5
Management of idiopathic recurrent pericarditis in adults and in children: a role for IL-1 receptor antagonism. ( 29633070 )
2018
6
Radical pericardiectomy for chronic constrictive pericarditis. ( 29761570 )
2018
7
Model for end-stage liver disease predicts mortality after pericardiectomy for constrictive pericarditis. ( 29893857 )
2018
8
Increased FDG-PET/CT pericardial uptake identifies acute pericarditis patients at high risk for relapse. ( 29884293 )
2018
9
Difficult diagnosis of heart failure in rheumatoid arthritis: six-year follow-up of constrictive pericarditis. ( 29558019 )
2018
10
Hairy cell leukemia presenting with progressive pericarditis and pleuritis. ( 29846761 )
2018
11
A Case of Constrictive Pericarditis Associated with Melioidosis in an Immunocompetent Patient Treated by Pericardiectomy. ( 29551765 )
2018
12
Constrictive Pericarditis. ( 29809259 )
2018
13
Acute Pericarditis as a Presentation of Adrenal Insufficiency. ( 29904615 )
2018
14
Kohlmeier-Degos disease with constrictive pericarditis and atrial fibrillation. ( 29974345 )
2018
15
Prodromal symptoms predict myocardial involvement in patients with acute idiopathic pericarditis. ( 29891235 )
2018
16
Successful Total Pericardiectomy for Constrictive Pericarditis in the First Series of Japanese Patients With Mulibrey Nanism. ( 29731032 )
2018
17
Recurrent purulent pericarditis secondary to a giant bronchogenic cyst. ( 29029080 )
2018
18
Anterior Pericardiectomy for Post Infective Constrictive Pericarditis; Intermediate Term Outcomes. ( 29777668 )
2018
19
The landscape of acute pericarditis in Greece: Experience from a tertiary referral center. ( 29940222 )
2018
20
Primary purulent bacterial pericarditis due to Streptococcus intermedius in an immunocompetent adult: a case report. ( 29397796 )
2018
21
Virulence of Escherichia coli Isolates Obtained from Layer Chickens with Colibacillosis Associated with Pericarditis, Perihepatitis, and Salpingitis in Experimentally Infected Chicks and Embryonated Eggs. ( 29944397 )
2018
22
An oil refinery worker at Kaohsiung, with Pseudoxanthomonas kaohsiungensis bloodstream infection presenting as chronic pericarditis and masquerading as tuberculosis pericarditis. ( 29366692 )
2018
23
Epithelioid angiosarcoma: A rare cause of pericarditis and pleural effusion. ( 29977765 )
2018
24
Pericarditis due to <i>Neisseria meningitidis</i> serogroup W135. ( 29942749 )
2018
25
Surgical Pericardiectomy for Constrictive Pericarditis: A Single Tertiary Center Experience. ( 29804284 )
2018
26
Clinical features, management and outcome of patients with constrictive pericarditis - Experience from a third world country. ( 29296059 )
2018
27
Pericardial Window for Methicillin-Resistant Staphylococcus Aureus Pericarditis. ( 29932888 )
2018
28
Genotype-phenotype investigation of 35 patients from 11 unrelated families with camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome. ( 29397575 )
2018
29
Constrictive pericarditis: retrospective study of 109 patients. ( 29703105 )
2018
30
Implantable epicardial cardioverter-defibrillator-induced localized constrictive pericarditis. ( 29049636 )
2018
31
Incremental Value of the Tissue Motion of Annular Displacement Derived From Speckle-Tracking Echocardiography for Differentiating Chronic Constrictive Pericarditis From Restrictive Cardiomyopathy. ( 29603321 )
2018
32
Pericarditis in a Department of Internal Medicine: causes and diagnostic work-up. ( 29846285 )
2018
33
Chylothorax and constrictive pericarditis in a woman due to generalized lymphatic anomaly: a case report. ( 29871646 )
2018
34
A rare case of pericarditis and pleural empyema secondary to transdiaphragmatic extension of pyogenic liver abscess. ( 29334903 )
2018
35
Purulent Pericarditis Due to Paronychia in a 16-Month-Old Child: A Nail-Biting Story. ( 29506451 )
2018
36
Acute pericarditis following endoscopy. ( 29437737 )
2018
37
Constrictive Pericarditis Presenting as Bilateral Pleural Effusion: A Report of Two Cases. ( 29888155 )
2018
38
IgG4-related periarteritis in the coronary artery and subclinical pericarditis assessed the presence and monitoring of therapy response by PET and CT scan. ( 29880627 )
2018
39
Longitudinal strain by speckle tracking echocardiography in constrictive pericarditis. ( 29529320 )
2018
40
Constrictive Pericarditis as a Long-term Undetermined Etiology of Ascites and Edema. ( 29321423 )
2018
41
18F-FDG PET/CT and MRI of a Mediastinal Malignant Granular Cell Tumor With Associated Recurrent Pericarditis. ( 29847320 )
2018
42
ECG Spot Diagnosis: Acute Pericarditis. ( 29432566 )
2018
43
Echocardiography with Elevated Central Venous Pressure Diagnosing Constrictive Pericarditis More Accurately Than Chest CT Scan: A Retrospective Study in 36 Cases. ( 29893679 )
2018
44
Granulomatosis with polyangiitis can cause periaortitis and pericarditis. ( 29026588 )
2017
45
Pericardiectomy for Constrictive Pericarditis: An Institution's 21 Years Experience. ( 28780766 )
2017
46
The Therapeutic Role of Interleukin-1 Inhibition in Idiopathic Recurrent Pericarditis: Current Evidence and Future Challenges. ( 28660191 )
2017
47
Diagnosis of systemic inflammatory diseases among patients admitted for acute pericarditis with pericardial effusion. ( 28937580 )
2017
48
Restrictive Cardiomyopathy or Constrictive Pericarditis: An Unresolved Conundrum. ( 29187041 )
2017
49
Pericardial interstitial cell senescence responsible for pericardial structural remodeling in idiopathic and postsurgical constrictive pericarditis. ( 28456362 )
2017
50
Constrictive pericarditis caused by Cutibacterium (Propionibacterium) acnes: A case report and review of literature. ( 29021959 )
2017

Variations for Pericarditis

Expression for Pericarditis

Search GEO for disease gene expression data for Pericarditis.

Pathways for Pericarditis

Pathways related to Pericarditis according to GeneCards Suite gene sharing:

(show all 49)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.31 HRH4 IL1B IL6 IRAK4 TNF TNFRSF1A
2
Show member pathways
12.82 IL1B IL6 IRAK4 MEFV TNF TNFRSF1A
3
Show member pathways
12.7 IL1B IL6 IRAK4 TNF TNFRSF1A
4 12.67 IL1B IRAK4 TNF TNFRSF1A
5
Show member pathways
12.57 IL1B TNF TNFRSF1A TRAF3IP2
6
Show member pathways
12.56 IL1B IL6 IRAK4 TNF TNFRSF1A
7 12.48 IL1B IRAK4 TNF TNFRSF1A
8
Show member pathways
12.4 IL1B IRAK4 TNF TNFRSF1A
9
Show member pathways
12.26 CRP IL1B IL6 TNF
10
Show member pathways
12.26 IL1B IL6 TNF TRAF3IP2
11
Show member pathways
12.16 IL1B IRAK4 TNF TNFRSF1A
12
Show member pathways
12.16 IL1B IL6 IRAK4 TNF
13
Show member pathways
12.13 IL1B IL6 IRAK4 TNF
14 12.1 IL6 TNF TNFRSF1A
15 12.09 IL1B IL6 TNF
16
Show member pathways
12.08 NPPB TNF TNFRSF1A
17
Show member pathways
12.05 IL1B IL6 IRAK4 TNF
18 12.01 IL1B TNF TNFRSF1A
19 11.97 IL1B TNF TNFRSF1A
20 11.93 IL1B IL6 TNF
21 11.9 IL1B IL6 TNF
22
Show member pathways
11.88 IL6 TNF TNFRSF1A
23 11.83 IL1B IL6 TNF
24 11.82 IL1B IL6 TNF
25 11.81 IL1B IL6 TNF
26 11.78 IL1B IL6 TNF
27 11.74 IL1B IL6 TNF TNFRSF1A
28 11.69 IL1B IL6 TNF
29 11.67 IRAK4 TNF TNFRSF1A
30 11.65 IL1B IRAK4 TNF TNFRSF1A
31 11.61 IL1B IL6 TNF
32 11.61 IL1B IL6 IRAK4 TNF TNFRSF1A
33 11.53 IL1B IL6 TNF
34 11.49 IL6 TNF TNFRSF1A
35 11.46 IL1B IL6 TNF
36 11.44 IL1B IL6 IRAK4 TNF
37 11.41 IL1B IL6 TNF
38
Show member pathways
11.26 IL1B IL6 TNF TNFRSF1A
39 11.24 IL1B IL6 TNF
40 11.23 IL1B IL6 TNF
41 11.16 IL1B IL6 TNF
42 11.12 IL1B IL6 TNF
43 11.09 IL1B IL6 TNF
44 11.06 TNF TNFRSF1A
45 11.04 IL1B TNF
46 11.03 IL6 TNF
47 10.88 IL1B TNF
48 10.78 CRP IL6 TNF
49 10.61 IL1B IL6 TNF TNFRSF1A

GO Terms for Pericarditis

Cellular components related to Pericarditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 CRP IL1B IL6 NPPB PRG4 TNF
2 extracellular space GO:0005615 9.23 ADA CRP IL1B IL6 IRAK4 NPPB

Biological processes related to Pericarditis according to GeneCards Suite gene sharing:

(show all 27)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.93 IL1B IL6 NPPB TNF
2 positive regulation of gene expression GO:0010628 9.92 CRP IL1B IL6 TNF
3 immune response GO:0006955 9.91 IL1B IL6 PRG4 TNF TNFRSF1A
4 positive regulation of DNA binding transcription factor activity GO:0051091 9.77 IL1B IL6 TNF
5 negative regulation of inflammatory response GO:0050728 9.77 ADA MEFV TNFRSF1A
6 defense response to Gram-positive bacterium GO:0050830 9.76 CRP IL6 TNF
7 cytokine-mediated signaling pathway GO:0019221 9.72 IL1B IL6 IRAK4 TNF TNFRSF1A
8 humoral immune response GO:0006959 9.7 IL6 TNF TRAF3IP2
9 positive regulation of smooth muscle cell proliferation GO:0048661 9.67 IL6 IRAK4 TNF
10 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.67 IL1B IL6 IRAK4 TNF
11 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.65 IL1B IRAK4 TNF TNFRSF1A TRAF3IP2
12 positive regulation of chemokine production GO:0032722 9.63 IL6 TNF
13 positive regulation of interleukin-6 production GO:0032755 9.63 IL1B IL6 TNF
14 embryonic digestive tract development GO:0048566 9.62 ADA TNF
15 negative regulation of lipid catabolic process GO:0050995 9.61 IL1B TNF
16 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.61 IL1B TNF
17 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.58 IL1B TNF
18 neutrophil mediated immunity GO:0002446 9.57 IL6 IRAK4
19 positive regulation of ceramide biosynthetic process GO:2000304 9.56 TNF TNFRSF1A
20 positive regulation of chemokine biosynthetic process GO:0045080 9.55 IL1B TNF
21 death-inducing signaling complex assembly GO:0071550 9.54 TNF TNFRSF1A
22 positive regulation of fever generation GO:0031622 9.48 IL1B TNF
23 sequestering of triglyceride GO:0030730 9.43 IL1B TNF
24 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.4 IL1B TNF
25 negative regulation of lipid storage GO:0010888 9.33 CRP IL6 TNF
26 inflammatory response GO:0006954 9.17 CRP HRH4 IL1B IL6 MEFV TNF
27 regulation of establishment of endothelial barrier GO:1903140 9.13 IL1B TNF TNFRSF1A

Molecular functions related to Pericarditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 8.62 IL1B IRAK4

Sources for Pericarditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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