MCID: PRC050
MIFTS: 22

Pericardium Disease

Categories: Cardiovascular diseases

Aliases & Classifications for Pericardium Disease

MalaCards integrated aliases for Pericardium Disease:

Name: Pericardium Disease 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050829
ICD10 34 I31.8

Summaries for Pericardium Disease

Disease Ontology : 12 A cardiovascular system disease that is located in the fibrous sac surrounding the heart.

MalaCards based summary : Pericardium Disease is related to pericardial effusion and pericarditis. An important gene associated with Pericardium Disease is IL1RN (Interleukin 1 Receptor Antagonist). Affiliated tissues include the fibrous sac surrounding the heart and heart, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Pericardium Disease

Diseases related to Pericardium Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 150)
# Related Disease Score Top Affiliating Genes
1 pericardial effusion 31.9 CRP NPPB PIK3C2A
2 pericarditis 31.5 CRP IL1RN MEFV NPPB PRG4
3 cryopyrin-associated periodic syndrome 10.4 CRP IL1RN
4 tick paralysis 10.4 PIK3C2A TNNI3
5 acute cholangitis 10.4 CRP IL1RN
6 hyper-igd syndrome 10.4 CRP IL1RN
7 schnitzler syndrome 10.4 CRP IL1RN
8 juvenile ankylosing spondylitis 10.4 IL1RN MEFV
9 trichostrongyloidiasis 10.4 ALB PIK3C2A
10 rheumatic myocarditis 10.4 CRP TNNI3
11 pyuria 10.4 ALB CRP
12 aortitis 10.4 CRP SMUG1
13 chondromalacia 10.4 IL1RN SMUG1
14 decubitus ulcer 10.3 ALB CRP
15 malignant otitis externa 10.3 CRP F2
16 relapsing fever 10.3 CRP MEFV
17 adult-onset still's disease 10.3 CRP IL1RN MEFV
18 cardiogenic shock 10.3 NPPB PIK3C2A
19 granulomatous myositis 10.3 PIK3C2A SMUG1
20 brucellosis 10.3 CRP IL1RN MEFV
21 synovitis 10.3 CRP IL1RN PRG4
22 erysipelas 10.3 MEFV PIK3C2A
23 cartilage disease 10.3 CRP IL1RN SMUG1
24 antipyrine metabolism 10.3 ALB F2
25 familial mediterranean fever 10.3 CRP IL1RN MEFV
26 anterior compartment syndrome 10.3 F2 PIK3C2A
27 non-a-e hepatitis 10.3 ALB F2
28 amyloidosis aa 10.3 CRP MEFV
29 temporal arteritis 10.3 CRP IL1RN SMUG1
30 epstein-barr virus hepatitis 10.3 ALB F2
31 exanthem 10.3 CRP IL1RN TRIM21
32 proteasome-associated autoinflammatory syndrome 1 10.3 ALB CRP IL1RN
33 hypersensitivity reaction type iii disease 10.3 ALB CRP MEFV
34 ischemic neuropathy 10.3 CRP F2
35 lactocele 10.3 SMUG1 TRIM21
36 blue toe syndrome 10.3 CRP F2
37 third-degree atrioventricular block 10.3 NPPB TRIM21
38 generalized atherosclerosis 10.3 ACE CRP
39 bacterial meningitis 10.3 ALB CRP PIK3C2A
40 gastrointestinal tuberculosis 10.3 ALB CRP SMUG1
41 fournier gangrene 10.3 ALB F2
42 gas gangrene 10.3 PIK3C2A TNNI3
43 acute anterolateral myocardial infarction 10.3 ACE PIK3C2A
44 loeffler syndrome 10.3 ACE ALB
45 primary bacterial infectious disease 10.3 ALB CRP MEFV
46 tuberculous peritonitis 10.3 ALB CRP SMUG1
47 klatskin's tumor 10.3 ALB SMUG1
48 lymphoid interstitial pneumonia 10.3 CRP TRIM21
49 non-secretory myeloma 10.3 ALB SMUG1
50 pleural disease 10.3 ALB CRP SMUG1

Graphical network of the top 20 diseases related to Pericardium Disease:



Diseases related to Pericardium Disease

Symptoms & Phenotypes for Pericardium Disease

MGI Mouse Phenotypes related to Pericardium Disease:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.76 ACE CRP F2 IL1RN NLRP6 PIK3C2A
2 homeostasis/metabolism MP:0005376 9.7 ACE ALB CRP F2 IL1RN MEFV
3 mortality/aging MP:0010768 9.36 ACE ALB F2 IL1RN MEFV NLRP6

Drugs & Therapeutics for Pericardium Disease

Search Clinical Trials , NIH Clinical Center for Pericardium Disease

Genetic Tests for Pericardium Disease

Anatomical Context for Pericardium Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Pericardium Disease:

20
The Fibrous Sac Surrounding The Heart

MalaCards organs/tissues related to Pericardium Disease:

42
Heart

Publications for Pericardium Disease

Variations for Pericardium Disease

Expression for Pericardium Disease

Search GEO for disease gene expression data for Pericardium Disease.

Pathways for Pericardium Disease

GO Terms for Pericardium Disease

Biological processes related to Pericardium Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.56 CRP IL1RN MEFV NLRP6
2 response to interferon-gamma GO:0034341 9.32 MEFV TRIM21
3 negative regulation of cytokine production involved in inflammatory response GO:1900016 9.16 F2 MEFV
4 heart contraction GO:0060047 8.96 ACE TNNI3
5 regulation of blood vessel diameter GO:0097746 8.62 ACE NPPB

Sources for Pericardium Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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