MCID: PRC050
MIFTS: 21

Pericardium Disease

Categories: Cardiovascular diseases

Aliases & Classifications for Pericardium Disease

MalaCards integrated aliases for Pericardium Disease:

Name: Pericardium Disease 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050829
ICD10 33 I31.8

Summaries for Pericardium Disease

Disease Ontology : 12 A cardiovascular system disease that is located in the fibrous sac surrounding the heart.

MalaCards based summary : Pericardium Disease is related to pericarditis and pericardial effusion. An important gene associated with Pericardium Disease is IL1RN (Interleukin 1 Receptor Antagonist). Affiliated tissues include the fibrous sac surrounding the heart, heart and thyroid, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Pericardium Disease

Diseases related to Pericardium Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 pericarditis 31.6 CRP IL1RN MEFV PRG4
2 pericardial effusion 11.0
3 cryopyrin-associated periodic syndrome 10.3 CRP IL1RN
4 acute cholangitis 10.3 CRP IL1RN
5 tick paralysis 10.3 PIK3C2A TNNI3
6 hyper-igd syndrome 10.3 CRP IL1RN
7 systemic onset juvenile idiopathic arthritis 10.3 IL1RN MEFV
8 schnitzler syndrome 10.3 CRP IL1RN
9 juvenile ankylosing spondylitis 10.3 IL1RN MEFV
10 rheumatic myocarditis 10.3 CRP TNNI3
11 abdominal tuberculosis 10.2 ALB CRP
12 trichostrongyloidiasis 10.2 ALB PIK3C2A
13 pyuria 10.2 ALB CRP
14 constrictive pericarditis 10.2 ALB IL1RN
15 aortitis 10.2 CRP SMUG1
16 chondromalacia 10.2 IL1RN SMUG1
17 relapsing fever 10.2 CRP MEFV
18 decubitus ulcer 10.2 ALB CRP
19 amyloidosis aa 10.2 CRP MEFV
20 erysipelas 10.2 MEFV PIK3C2A
21 gas gangrene 10.2 PIK3C2A TNNI3
22 granulomatous myositis 10.2 PIK3C2A SMUG1
23 synovitis 10.2 CRP IL1RN PRG4
24 adult-onset still's disease 10.2 CRP IL1RN MEFV
25 intermediate coronary syndrome 10.2 CRP PIK3C2A TNNI3
26 brucellosis 10.2 CRP IL1RN MEFV
27 extrinsic cardiomyopathy 10.2 CRP PIK3C2A TNNI3
28 inferior myocardial infarction 10.2 PIK3C2A SULT1E1
29 familial mediterranean fever 10.2 CRP IL1RN MEFV
30 hepatic tuberculosis 10.2 ALB SMUG1
31 cartilage disease 10.2 CRP IL1RN SMUG1
32 proteasome-associated autoinflammatory syndrome 1 10.2 ALB CRP IL1RN
33 temporal arteritis 10.2 CRP IL1RN SMUG1
34 posterior myocardial infarction 10.2 PIK3C2A SULT1E1
35 pulmonary embolism 10.2 ALB CRP TNNI3
36 central nervous system vasculitis 10.2 CRP SMUG1
37 klatskin's tumor 10.2 ALB SMUG1
38 peritonitis 10.2 ALB CRP MEFV
39 hypersensitivity reaction type iii disease 10.2 ALB CRP MEFV
40 bacterial meningitis 10.2 ALB CRP PIK3C2A
41 non-secretory myeloma 10.2 ALB SMUG1
42 primary bacterial infectious disease 10.2 ALB CRP MEFV
43 pulmonary aspergilloma 10.2 CRP SMUG1
44 left bundle branch hemiblock 10.1 SULT1E1 TNNI3
45 acute myocardial infarction 10.1 CRP PIK3C2A TNNI3
46 respiratory failure 10.1 ALB CRP PIK3C2A
47 lymphoid interstitial pneumonia 10.1 CRP TRIM21
48 toxic myocarditis 10.1 PIK3C2A TNNI3 ZIC3
49 gastrointestinal tuberculosis 10.1 ALB CRP SMUG1
50 tuberculous peritonitis 10.1 ALB CRP SMUG1

Graphical network of the top 20 diseases related to Pericardium Disease:



Diseases related to Pericardium Disease

Symptoms & Phenotypes for Pericardium Disease

MGI Mouse Phenotypes related to Pericardium Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.76 ACVRL1 CRP IL1RN NLRP6 PIK3C2A SULT1E1
2 homeostasis/metabolism MP:0005376 9.65 ACVRL1 ALB CRP IL1RN MEFV NLRP6
3 mortality/aging MP:0010768 9.36 ACVRL1 ALB IL1RN MEFV NLRP6 PES1

Drugs & Therapeutics for Pericardium Disease

Search Clinical Trials , NIH Clinical Center for Pericardium Disease

Genetic Tests for Pericardium Disease

Anatomical Context for Pericardium Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Pericardium Disease:

19
The Fibrous Sac Surrounding The Heart

MalaCards organs/tissues related to Pericardium Disease:

41
Heart, Thyroid

Publications for Pericardium Disease

Variations for Pericardium Disease

Expression for Pericardium Disease

Search GEO for disease gene expression data for Pericardium Disease.

Pathways for Pericardium Disease

GO Terms for Pericardium Disease

Biological processes related to Pericardium Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to interferon-gamma GO:0034341 8.96 MEFV TRIM21
2 inflammatory response GO:0006954 8.92 CRP IL1RN MEFV NLRP6

Sources for Pericardium Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....