MCID: PRC055
MIFTS: 11

Pericytoma with T(7;12)

Categories: Cancer diseases, Cardiovascular diseases

Aliases & Classifications for Pericytoma with T(7;12)

MalaCards integrated aliases for Pericytoma with T(7;12):

Name: Pericytoma with T(7;12) 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0080896

Summaries for Pericytoma with T(7;12)

Disease Ontology : 12 A perivascular tumor that is characterized by a perivascular pattern of spindle-to-ovoid cell proliferation and that has material basis in t(7;12)(p22;q13) translocation with resultant ACTB-GLI1 fusion.

MalaCards based summary : Pericytoma with T(7;12) is related to mesenchymal cell neoplasm and myopericytoma. An important gene associated with Pericytoma with T(7;12) is ACTB (Actin Beta), and among its related pathways/superpathways is G-Beta Gamma Signaling. Related phenotype is neoplasm.

Related Diseases for Pericytoma with T(7;12)

Diseases related to Pericytoma with T(7;12) via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 mesenchymal cell neoplasm 10.3
2 myopericytoma 10.3
3 ewing sarcoma 9.6 GLI1 ACTB
4 bardet-biedl syndrome 9.6 GLI1 ACTB
5 skin carcinoma 9.5 GLI1 ACTB

Graphical network of the top 20 diseases related to Pericytoma with T(7;12):



Diseases related to Pericytoma with T(7;12)

Symptoms & Phenotypes for Pericytoma with T(7;12)

MGI Mouse Phenotypes related to Pericytoma with T(7;12):

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.62 ACTB GLI1

Drugs & Therapeutics for Pericytoma with T(7;12)

Search Clinical Trials , NIH Clinical Center for Pericytoma with T(7;12)

Genetic Tests for Pericytoma with T(7;12)

Anatomical Context for Pericytoma with T(7;12)

Publications for Pericytoma with T(7;12)

Articles related to Pericytoma with T(7;12):

# Title Authors PMID Year
1
Pericytoma With t(7;12) and ACTB-GLI1 Fusion: Reevaluation of an Unusual Entity and its Relationship to the Spectrum of GLI1 Fusion-related Neoplasms. 61
31567194 2019
2
Pericytoma With t(7;12): The First Ovarian Case Reported and a Review of the Literature. 61
30085941 2019
3
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions. 61
29309307 2018
4
Translocation t(7;12) as the sole chromosomal abnormality resulting in ACTB-GLI1 fusion in pediatric gastric pericytoma. 61
26980027 2016
5
Pericytoma with t(7;12) and ACTB-GLI1 fusion arising in bone. 61
22575261 2012
6
Molecular genetic characterization of the genomic ACTB-GLI fusion in pericytoma with t(7;12). 61
15555571 2004
7
Activation of the GLI oncogene through fusion with the beta-actin gene (ACTB) in a group of distinctive pericytic neoplasms: pericytoma with t(7;12). 61
15111311 2004

Variations for Pericytoma with T(7;12)

Expression for Pericytoma with T(7;12)

Search GEO for disease gene expression data for Pericytoma with T(7;12).

Pathways for Pericytoma with T(7;12)

Pathways related to Pericytoma with T(7;12) according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.49 GLI1 ACTB

GO Terms for Pericytoma with T(7;12)

Sources for Pericytoma with T(7;12)

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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