MCID: PRN007
MIFTS: 33

Perinephritis

Categories: Nephrological diseases

Aliases & Classifications for Perinephritis

MalaCards integrated aliases for Perinephritis:

Name: Perinephritis 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:2982
MeSH 44 D010501
UMLS 73 C0031065

Summaries for Perinephritis

MalaCards based summary : Perinephritis is related to tempi syndrome and pyelonephritis. An important gene associated with Perinephritis is REN (Renin), and among its related pathways/superpathways are Peptide ligand-binding receptors and Vascular smooth muscle contraction. Affiliated tissues include kidney, smooth muscle and skeletal muscle, and related phenotypes are homeostasis/metabolism and muscle

Related Diseases for Perinephritis

Diseases related to Perinephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 124)
# Related Disease Score Top Affiliating Genes
1 tempi syndrome 11.9
2 pyelonephritis 10.2
3 malignant hypertensive renal disease 10.2 EDN1 REN
4 malignant renovascular hypertension 10.2 EDN1 REN
5 renovascular hypertension 10.1 EDN1 REN
6 malignant secondary hypertension 10.1 EDN1 REN
7 renal cell carcinoma, nonpapillary 10.1
8 mandibulofacial dysostosis with alopecia 10.1 EDN1 EDNRA
9 malignant hypertension 10.1 EDN1 REN
10 renal tuberculosis 10.1 EDN1 REN
11 hepatorenal syndrome 10.1 EDN1 REN
12 renal hypertension 10.1 EDN1 REN
13 bullous impetigo 10.1 EDNRA EDNRB
14 hepatic vascular disease 10.1 EDN1 REN
15 persistent fetal circulation syndrome 10.1 EDN1 EDNRA
16 ritter's disease 10.1 EDNRA EDNRB
17 aortic coarctation 10.1 ADRB2 EDN1
18 scarlet fever 10.1 EDNRA EDNRB
19 apnea, obstructive sleep 10.1 EDN1 REN
20 polyarteritis nodosa, childhood-onset 10.1
21 xanthogranulomatous pyelonephritis 10.1
22 polyarteritis nodosa 10.1
23 radiation proctitis 10.1 EDNRA EDNRB
24 nephrogenic systemic fibrosis 10.1 EDN1 EDNRA
25 idiopathic hypercalciuria 10.1 EDN1 REN
26 obstructive jaundice 10.1 EDN1 REN
27 acute poststreptococcal glomerulonephritis 10.1 EDN1 EDNRB
28 acute mountain sickness 10.1 ADRB2 EDN1
29 oligohydramnios 10.1 EDN1 REN
30 hydronephrosis 10.1
31 angiomyolipoma 10.1
32 pulmonary edema 10.0 EDN1 REN
33 portal hypertension 10.0 EDN1 EDNRA
34 sleep apnea 10.0 EDN1 REN
35 hepatopulmonary syndrome 10.0 EDN1 EDNRB
36 kidney disease 10.0 EDN1 EDNRA REN
37 benign essential hypertension 10.0 MGAM REN
38 congestive heart failure 10.0 ADRB2 EDN1 REN
39 functional diarrhea 10.0 EDN1 HTR7
40 arteries, anomalies of 10.0 EDN1 REN
41 clear cell renal cell carcinoma 10.0
42 adenoma 10.0
43 kidney angiomyolipoma 10.0
44 space motion sickness 10.0 MGAM REN
45 premenstrual tension 10.0 MGAM REN
46 eclampsia 10.0 EDN1 REN
47 mineral metabolism disease 9.9 MGAM REN
48 connective tissue disease 9.9 EDN1 EDNRA EDNRB
49 oncocytoma 9.9
50 renal oncocytoma 9.9

Graphical network of the top 20 diseases related to Perinephritis:



Diseases related to Perinephritis

Symptoms & Phenotypes for Perinephritis

MGI Mouse Phenotypes related to Perinephritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.7 ADRB2 EDN1 EDNRA EDNRB HTR7 MGAM
2 muscle MP:0005369 9.35 ADRB2 EDN1 EDNRA EDNRB REN
3 nervous system MP:0003631 9.1 ADRB2 EDN1 EDNRA EDNRB HTR7 REN

Drugs & Therapeutics for Perinephritis

Search Clinical Trials , NIH Clinical Center for Perinephritis

Cochrane evidence based reviews: perinephritis

Genetic Tests for Perinephritis

Anatomical Context for Perinephritis

MalaCards organs/tissues related to Perinephritis:

41
Kidney, Smooth Muscle, Skeletal Muscle, Liver, Heart, B Cells, Cortex

Publications for Perinephritis

Articles related to Perinephritis:

(show all 41)
# Title Authors Year
1
Bilateral xanthogranulomatous perinephritis without renal parenchymal involvement. ( 10879698 )
2000
2
Page kidney with constrictive perinephritis. ( 8341012 )
1993
3
Effects of endothelin upon blood pressure in normotensive rabbits and in perinephritis hypertension. ( 1325511 )
1992
4
Noradrenaline and endothelin-stimulated inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. ( 1794209 )
1991
5
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension. ( 2208798 )
1990
6
Inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. ( 1962806 )
1990
7
Perinephritis hypertension in Macaca fascicularis (cynomolgus monkey): studies of the renin-angiotensin-aldosterone axis and renal hemodynamic function. ( 2677140 )
1989
8
Platelet cytosolic free calcium before and after antihypertensive treatment in perinephritis hypertension of the rabbit. ( 2571432 )
1989
9
Skeletal muscle beta 2-adrenoreceptors and the effect of adrenergic drugs on plasma potassium in perinephritis hypertension in rabbits. ( 2541134 )
1989
10
Desensitization of vascular and platelet alpha 2-adrenoceptors in rabbits with perinephritis hypertension. ( 2897989 )
1988
11
Electrophysiological properties of the mesenteric artery of the rabbit with perinephritis hypertension. ( 3390614 )
1988
12
45Ca uptake and the actions of Bay K 8644 on aortic strips from rabbits with perinephritis hypertension. ( 2448370 )
1987
13
Perisplenitis and perinephritis in the Curtis-Fitz-Hugh syndrome. ( 3815024 )
1987
14
Studies on alpha 2-adrenoceptors in rabbits with perinephritis hypertension. ( 2870119 )
1986
15
Alterations of the glomerular beta-adrenoceptor-linked adenylate cyclase system in perinephritis hypertension. ( 2419695 )
1986
16
Cardiac and lymphocyte beta-adrenoceptors in perinephritis hypertension in the rabbit. ( 2425174 )
1986
17
Xanthogranulomatous perinephritis: unusual cause of renal vein and vena caval thrombosis. ( 3984116 )
1985
18
Systemic and regional haemodynamic profile of captopril in conscious rabbits with bilateral cellophane perinephritis hypertension. ( 3912085 )
1985
19
Alpha adrenoceptors and autonomic mechanisms in perinephritis hypertension in the rabbit. ( 6317553 )
1983
20
Systemic and regional hemodynamic characteristics of bilateral cellophane perinephritis hypertension in conscious rabbits. ( 6883748 )
1983
21
Serum angiotensin converting enzyme activity and the capacity to develop hypertention-associated arterial disease. Studies during the induction phase of one-kidney perinephritis hypertension in rabbits. ( 213977 )
1978
22
Hemodynamic effects of an angiotensin II antagonist in rabbits with perinephritis hypertension. ( 866354 )
1977
23
Perinephritis hypertension in monkeys. I. An increase of plasma renin activity associated with increased permeability of retinal vessels and angionecrosis. ( 6807 )
1976
24
Role of the renin-angiotensin system in dogs with perinephritis hypertension. ( 967886 )
1976
25
Increased serum cholesterol and non-esterified fatty acid levels in rats with constrictive perinephritis and maintained on normal diet. ( 4841653 )
1974
26
Colonic changes secondary to left perinephritis: new observations. ( 4828982 )
1974
27
Cellophane perinephritis hypertension and its reversal in rabbits. Effect on plasma renin, renin substrate, and renal mass. ( 4358201 )
1973
28
Renal cortical abscess, perinephritis and perinephric abscess in diabetes. ( 4713176 )
1973
29
A case of perinephritis with renal artery stenosis and hypertension. ( 5654387 )
1968
30
Hypertension associated with traumatic perinephritis. ( 13988619 )
1963
31
Perinephritis plastica. ( 13234106 )
1955
32
Perinephritis plastica. ( 13216975 )
1954
33
II. Establishment of hypertension in rats; hypertension caused by perinephritis. ( 13002117 )
1952
34
Perinephritis and perinephric abscess; a study of 37 cases. ( 18135670 )
1949
35
Latex rubber capsule for producing hypertension in rats by perinephritis. ( 20239439 )
1947
36
Perinephritis with and without operation. ( 20247050 )
1946
37
Perinephritis and perirenal abscess. ( 20279545 )
1946
38
The pathological anatomy of cellophane perinephritis. ( 19970495 )
1940
39
Perinephritis - Suppurative and Nonsuppurative. ( 18742440 )
1933
40
Perinephritis. ( 18742659 )
1933
41
Acute Non-Suppurative Perinephritis. ( 20760378 )
1902

Variations for Perinephritis

Expression for Perinephritis

Search GEO for disease gene expression data for Perinephritis.

Pathways for Perinephritis

GO Terms for Perinephritis

Biological processes related to Perinephritis according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.91 ADRB2 EDN1 EDNRA EDNRB HTR7
2 cell surface receptor signaling pathway GO:0007166 9.78 ADRB2 EDN1 EDNRB
3 response to lipopolysaccharide GO:0032496 9.72 EDN1 EDNRB REN
4 positive regulation of cytosolic calcium ion concentration GO:0007204 9.7 EDN1 EDNRA EDNRB
5 cellular response to drug GO:0035690 9.62 EDN1 REN
6 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193 9.62 EDN1 EDNRA
7 sensory perception of pain GO:0019233 9.61 EDN1 EDNRB
8 respiratory gaseous exchange GO:0007585 9.6 EDN1 EDNRA
9 activation of adenylate cyclase activity GO:0007190 9.59 ADRB2 EDNRA
10 regulation of sensory perception of pain GO:0051930 9.58 EDN1 EDNRB
11 branching involved in blood vessel morphogenesis GO:0001569 9.58 EDN1 EDNRA
12 neural crest cell development GO:0014032 9.57 EDN1 EDNRA
13 regulation of pH GO:0006885 9.56 EDN1 EDNRB
14 smooth muscle contraction GO:0006939 9.54 EDNRA HTR7
15 positive regulation of renal sodium excretion GO:0035815 9.49 EDN1 EDNRB
16 positive regulation of urine volume GO:0035810 9.48 EDN1 EDNRB
17 enteric nervous system development GO:0048484 9.46 EDNRA EDNRB
18 artery smooth muscle contraction GO:0014824 9.43 EDN1 EDNRA
19 regulation of glucose transmembrane transport GO:0010827 9.4 EDN1 EDNRA
20 epithelial fluid transport GO:0042045 9.37 EDN1 EDNRB
21 negative regulation of cellular protein metabolic process GO:0032269 9.32 EDN1 EDNRB
22 vein smooth muscle contraction GO:0014826 9.26 EDN1 EDNRB
23 regulation of blood pressure GO:0008217 9.26 EDN1 EDNRA EDNRB REN
24 endothelin receptor signaling pathway GO:0086100 9.16 EDNRA EDNRB
25 vasoconstriction GO:0042310 8.92 EDN1 EDNRA EDNRB HTR7

Molecular functions related to Perinephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor activity GO:0004930 9.26 ADRB2 EDNRA EDNRB HTR7
2 endothelin receptor activity GO:0004962 8.62 EDNRA EDNRB

Sources for Perinephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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