MCID: PRN007
MIFTS: 34

Perinephritis

Categories: Nephrological diseases

Aliases & Classifications for Perinephritis

MalaCards integrated aliases for Perinephritis:

Name: Perinephritis 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:2982
MeSH 44 D010501
SNOMED-CT 68 111404004
UMLS 73 C0031065

Summaries for Perinephritis

MalaCards based summary : Perinephritis is related to arteries, anomalies of and tempi syndrome. An important gene associated with Perinephritis is REN (Renin), and among its related pathways/superpathways are Peptide ligand-binding receptors and Vascular smooth muscle contraction. Affiliated tissues include kidney, colon and smooth muscle, and related phenotypes are homeostasis/metabolism and muscle

Related Diseases for Perinephritis

Diseases related to Perinephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
# Related Disease Score Top Affiliating Genes
1 arteries, anomalies of 28.9 EDN1 REN
2 tempi syndrome 11.7
3 malignant renovascular hypertension 10.5 EDN1 REN
4 malignant secondary hypertension 10.5 EDN1 REN
5 mandibulofacial dysostosis with alopecia 10.4 EDN1 EDNRA
6 renal tuberculosis 10.4 EDN1 REN
7 malignant hypertension 10.4 EDN1 REN
8 renal hypertension 10.4 EDN1 REN
9 hepatorenal syndrome 10.4 EDN1 REN
10 bullous impetigo 10.4 EDNRA EDNRB
11 ritter's disease 10.3 EDNRA EDNRB
12 aortic coarctation 10.3 ADRB2 EDN1
13 scarlet fever 10.3 EDNRA EDNRB
14 hepatic vascular disease 10.3 EDN1 REN
15 radiation proctitis 10.3 EDNRA EDNRB
16 persistent fetal circulation syndrome 10.3 EDN1 EDNRA
17 apnea, obstructive sleep 10.3 EDN1 REN
18 renovascular hypertension 10.3 EDN1 REN
19 idiopathic hypercalciuria 10.3 EDN1 REN
20 nephrogenic systemic fibrosis 10.2 EDN1 EDNRA
21 acute poststreptococcal glomerulonephritis 10.2 EDN1 EDNRB
22 obstructive jaundice 10.2 EDN1 REN
23 acute mountain sickness 10.2 ADRB2 EDN1
24 pulmonary edema 10.1 EDN1 REN
25 chronic pulmonary heart disease 10.1 EDN1 HTR7
26 pyelonephritis 10.1
27 portal hypertension 10.0 EDN1 EDNRA
28 benign essential hypertension 10.0 MGAM REN
29 sleep apnea 10.0 EDN1 REN
30 xanthogranulomatous pyelonephritis 10.0
31 premenstrual tension 9.9 MGAM REN
32 urinary system disease 9.9 EDN1 REN
33 polyarteritis nodosa, childhood-onset 9.9
34 hydronephrosis 9.9
35 adenoma 9.9
36 polyarteritis nodosa 9.9
37 hepatopulmonary syndrome 9.8 EDN1 EDNRA EDNRB
38 oncocytoma 9.8
39 hepatitis 9.8
40 renal oncocytoma 9.8
41 lymphoma 9.8
42 neurogenic bladder 9.8
43 ureterolithiasis 9.8
44 splenic abscess 9.8
45 liposarcoma 9.8
46 ureteral obstruction 9.8
47 lymphangiomatosis 9.8
48 mineral metabolism disease 9.8 MGAM REN
49 renal cell carcinoma, nonpapillary 9.6
50 pemphigus vulgaris, familial 9.6

Graphical network of the top 20 diseases related to Perinephritis:



Diseases related to Perinephritis

Symptoms & Phenotypes for Perinephritis

MGI Mouse Phenotypes related to Perinephritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.7 ADRB2 EDN1 EDNRA EDNRB HTR7 MGAM
2 muscle MP:0005369 9.35 ADRB2 EDN1 EDNRA EDNRB REN
3 nervous system MP:0003631 9.1 ADRB2 EDN1 EDNRA EDNRB HTR7 REN

Drugs & Therapeutics for Perinephritis

Search Clinical Trials , NIH Clinical Center for Perinephritis

Cochrane evidence based reviews: perinephritis

Genetic Tests for Perinephritis

Anatomical Context for Perinephritis

MalaCards organs/tissues related to Perinephritis:

41
Kidney, Colon, Smooth Muscle, B Cells, Skeletal Muscle, Lymph Node

Publications for Perinephritis

Articles related to Perinephritis:

(show top 50) (show all 95)
# Title Authors Year
1
Perinephric fat stranding is associated with elevated creatinine among patients with acutely obstructing ureterolithiasis. ( 29943669 )
2018
2
Inflammatory myofibroblastic tumor of kidney together with ipsilateral perinephric and periureteric fibrosis: A case report and literature review. ( 29245241 )
2017
3
Basidiobolomycosis complicated by hydronephrosis and a perinephric abscess presenting as a hypertensive emergency in a 7-year-old boy. ( 28112037 )
2017
4
Erdheim-Chester Disease with atrial mass and perinephric calcification. ( 29225878 )
2017
5
High-grade transitional cell carcinoma masquerading as a xanthogranulomatous pyelonephritis and perinephric abscess. ( 28491170 )
2017
6
Renal Oncocytoma With Perinephric Fat Invasion. ( 27170678 )
2016
7
Severe Hydronephrosis and Perinephric Urinoma with Rupture of Renal Fornix Secondary to Postoperative Urinary Retention following Laparoscopic Umbilical Hernia Repair. ( 27555977 )
2016
8
Perinephric adipose tissue thickness in relation to blood pressure, plasma apelin and C-reactive protein levels in obese adolescents. ( 24896245 )
2016
9
Diagnosis of perinephric retroperitoneal lymphangioma supported by contrast-enhanced ultrasound (CEUS). ( 27716656 )
2016
10
Perinephric Stranding and Bulky Psoas Mimicking Pyelonephritis in a Case of Non-Hodgkin Lymphoma of Kidney. ( 25813655 )
2015
11
Endometriosis in a kidney with focal xanthogranulomatous pyelonephritis and a perinephric abscess. ( 26490542 )
2015
12
Case report: a 37-year-old male with telangiectasias, polycythemia vera, perinephric fluid collections, and intrapulmonary shunting. ( 25143825 )
2014
13
Spontaneous perinephric hemorrhage (Wunderlich syndrome) secondary to polyarteritis nodosa: Computed tomography and angiographic findings. ( 25378832 )
2014
14
Nephrogenic adenoma: a report of 3 unusual cases infiltrating into perinephric adipose tissue. ( 23426119 )
2013
15
Bilateral psoas and bilateral perinephric abscesses complicating acute pyelonephritis in pregnancy. ( 23580809 )
2013
16
Bilateral subcapsular and perinephric hemorrhage as the initial presentation of polyarteritis nodosa. ( 22576390 )
2012
17
Radiology-pathology conference: primary perinephric and renal extraosseous Ewing's sarcoma. ( 22226450 )
2012
18
Perinephric drain - an unusual suspect of ureteral obstruction after open pyelolithotomy. ( 22482393 )
2012
19
Cystitis, pyelonephritis and perinephric abscess due to ureaplasma urealyticum. ( 23000853 )
2012
20
Perinephric extramedullary haematopoiesis in primary myelofibrosis. ( 22329535 )
2012
21
Urgent referrals. Eczema herpeticum, pemphigus vulgaris, perinephric abscess, quinsy, necrotising fasciitis. ( 21510509 )
2011
22
Waldenstrom's macroglobulinemia presenting as a perinephric mass. ( 21944982 )
2011
23
Stage pT3a of renal clear cell carcinoma: do tumors with sinus fat involvement behave the same as those with perinephric fat involvement? ( 21655644 )
2011
24
A case of perinephric liposarcoma which recurred ten years later from the initial operation. ( 21372501 )
2011
25
Computed tomography findings in bilateral perinephric lymphangiomatosis. ( 20842254 )
2010
26
Spontaneous perinephric haemorrhage and acute renal failure in pregnancy due to cocaine intoxication. ( 28657049 )
2010
27
Case report: Perinephric lymphangiomatosis. ( 21042452 )
2010
28
Pseudosarcomatous fibroblastic/myofibroblastic proliferation in perinephric adipose tissue adjacent to renal cell carcinoma: a lesion mimicking well-differentiated liposarcoma. ( 19525929 )
2009
29
Bilateral perinephric diffuse large B-cell lymphoma and synchronous renal oncocytoma. ( 18364624 )
2008
30
Pyomyositis with hepatic and perinephric abscesses caused by Candida albicans in a diabetic nephropathy patient. ( 16702803 )
2006
31
Perinephric angiomyolipoma: a unique development pattern surrounding the kidney. ( 15828960 )
2005
32
Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in perinephric lymph nodes. ( 16196523 )
2005
33
Superinfection of perinephric abscess by Stenotrophomonas maltophilia in a tetraplegic patient. ( 15672091 )
2005
34
Left perinephric abscess associated with nephrolithiasis and bladder calculi in a bitch. ( 15144002 )
2004
35
Perinephric urinoma secondary to neurogenic bladder with vesicoureteral reflux: report of an adult case. ( 14678187 )
2004
36
A model for perinephric fluid accumulation in uremic rats with toxic nephrosis. ( 14615063 )
2003
37
Perinephric cystic mesoblastic nephroma complicated by hepatic metastases: a case report. ( 12389112 )
2002
38
In utero perinephric urinoma and urinary ascites with posterior urethral valves: a paradoxical pop-off valve? ( 11696793 )
2001
39
Perinephric hematoma and massive gastrointestinal hemorrhage (GIB) complicating polyarteritis nodosa (PAN). ( 10843248 )
2000
40
Bilateral xanthogranulomatous perinephritis without renal parenchymal involvement. ( 10879698 )
2000
41
Acute ureterolithiasis: nonenhanced helical CT findings of perinephric edema for prediction of degree of ureteral obstruction. ( 10580936 )
1999
42
Perinephric urinoma secondary to neurogenic bladder in myelodysplasia. ( 7815619 )
1995
43
Image interpretation session: 1993. Spontaneous rupture of a renal adenoma with perinephric hemorrhage. ( 8128056 )
1994
44
Page kidney with constrictive perinephritis. ( 8341012 )
1993
45
Effects of endothelin upon blood pressure in normotensive rabbits and in perinephritis hypertension. ( 1325511 )
1992
46
Klebsiella pneumoniae urinary tract infection complicated by endophthalmitis, perinephric abscess, and ecthyma gangrenosum. ( 2052978 )
1991
47
Noradrenaline and endothelin-stimulated inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. ( 1794209 )
1991
48
Xanthogranulomatous pyelonephritis, perinephric type--a case report. ( 1942997 )
1991
49
Bilateral excision of perinephric fat and fascia (Gerota's fasciectomy) in the treatment of intractable chyluria. ( 1942297 )
1991
50
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension. ( 2208798 )
1990

Variations for Perinephritis

Expression for Perinephritis

Search GEO for disease gene expression data for Perinephritis.

Pathways for Perinephritis

GO Terms for Perinephritis

Biological processes related to Perinephritis according to GeneCards Suite gene sharing:

(show all 26)
# Name GO ID Score Top Affiliating Genes
1 G-protein coupled receptor signaling pathway GO:0007186 9.92 ADRB2 EDN1 EDNRA EDNRB HTR7
2 cell surface receptor signaling pathway GO:0007166 9.78 ADRB2 EDN1 EDNRB
3 response to lipopolysaccharide GO:0032496 9.74 EDN1 EDNRB REN
4 positive regulation of cytosolic calcium ion concentration GO:0007204 9.69 EDN1 EDNRA EDNRB
5 cellular response to drug GO:0035690 9.63 EDN1 REN
6 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway GO:0007193 9.62 EDN1 EDNRA
7 calcium-mediated signaling GO:0019722 9.62 EDN1 EDNRB
8 sensory perception of pain GO:0019233 9.61 EDN1 EDNRB
9 respiratory gaseous exchange GO:0007585 9.6 EDN1 EDNRA
10 activation of adenylate cyclase activity GO:0007190 9.59 ADRB2 EDNRA
11 branching involved in blood vessel morphogenesis GO:0001569 9.58 EDN1 EDNRA
12 regulation of sensory perception of pain GO:0051930 9.58 EDN1 EDNRB
13 neural crest cell development GO:0014032 9.56 EDN1 EDNRA
14 smooth muscle contraction GO:0006939 9.55 EDNRA HTR7
15 regulation of pH GO:0006885 9.54 EDN1 EDNRB
16 positive regulation of renal sodium excretion GO:0035815 9.49 EDN1 EDNRB
17 positive regulation of urine volume GO:0035810 9.48 EDN1 EDNRB
18 artery smooth muscle contraction GO:0014824 9.46 EDN1 EDNRA
19 enteric nervous system development GO:0048484 9.43 EDNRA EDNRB
20 regulation of glucose transmembrane transport GO:0010827 9.4 EDN1 EDNRA
21 negative regulation of cellular protein metabolic process GO:0032269 9.37 EDN1 EDNRB
22 epithelial fluid transport GO:0042045 9.32 EDN1 EDNRB
23 vein smooth muscle contraction GO:0014826 9.26 EDN1 EDNRB
24 regulation of blood pressure GO:0008217 9.26 EDN1 EDNRA EDNRB REN
25 endothelin receptor signaling pathway GO:0086100 9.16 EDNRA EDNRB
26 vasoconstriction GO:0042310 8.92 EDN1 EDNRA EDNRB HTR7

Molecular functions related to Perinephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 obsolete signal transducer activity GO:0004871 9.33 ADRB2 EDNRA EDNRB
2 G-protein coupled receptor activity GO:0004930 9.26 ADRB2 EDNRA EDNRB HTR7
3 endothelin receptor activity GO:0004962 8.62 EDNRA EDNRB

Sources for Perinephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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