MCID: PRN022
MIFTS: 36

Perineurioma

Categories: Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Perineurioma

MalaCards integrated aliases for Perineurioma:

Name: Perineurioma 12 53 55 15 73
Soft Tissue Perineurioma 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4697
MeSH 44 D018317
NCIt 50 C4973 C6912

Summaries for Perineurioma

MalaCards based summary : Perineurioma, also known as soft tissue perineurioma, is related to intraneural perineurioma and sclerosing perineurioma. An important gene associated with Perineurioma is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways/superpathways are Adhesion and Cardiac Progenitor Differentiation. Affiliated tissues include colon, tongue and skin, and related phenotypes are Decreased cell migration and behavior/neurological

Related Diseases for Perineurioma

Diseases related to Perineurioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 169)
# Related Disease Score Top Affiliating Genes
1 intraneural perineurioma 33.6 ALK MUC1 S100B SLC2A1
2 sclerosing perineurioma 33.6 MUC1 S100B
3 reticular perineurioma 33.4 KIT MUC1 S100B
4 neurofibroma 30.7 KIT MUC1 S100B
5 localized hypertrophic neuropathy 30.6 MUC1 S100B
6 granular cell tumor 30.5 S100B VIM
7 neurofibromatosis, type i 30.3 KIT NCAM1
8 neurilemmoma 30.2 KIT S100B VIM
9 histiocytoma 30.2 ALK KIT
10 malignant peripheral nerve sheath tumor 30.2 KIT MUC1 S100B VIM
11 fibrous histiocytoma 30.1 S100B VIM
12 sarcoma, synovial 29.9 KIT MUC1 VIM
13 cellular schwannoma 29.7 DSP S100B SLC2A1
14 gastrointestinal stromal tumor 29.4 KIT NCAM1 S100B VIM
15 extraneural perineurioma 12.3
16 malignant peripheral nerve sheath tumor with perineurial differentiation 11.2
17 neuropathy 10.3
18 neurofibrosarcoma 10.2
19 intracranial cysts 10.2 MUC1 S100B
20 non-functioning pituitary adenoma 10.2 MUC1 S100B
21 functioning pituitary adenoma 10.2 MUC1 S100B
22 epithelioid malignant peripheral nerve sheath tumor 10.2 MUC1 S100B
23 spindle cell rhabdomyosarcoma 10.2 MUC1 S100B
24 chordoid glioma 10.2 MUC1 S100B
25 papillary adenocarcinoma 10.2 MUC1 VIM
26 carpal tunnel syndrome 10.2
27 mononeuropathy of the median nerve, mild 10.2
28 sarcoma 10.2
29 mixed type thymoma 10.2 KIT S100B
30 adenofibroma 10.2 MUC1 VIM
31 sarcomatoid renal cell carcinoma 10.2 KIT MUC1
32 malignant peritoneal mesothelioma 10.2 MUC1 VIM
33 papilloma of choroid plexus 10.2 MUC1 S100B
34 papillary tumor of the pineal region 10.2 MUC1 VIM
35 parachordoma 10.2 MUC1 VIM
36 secretory meningioma 10.2 MUC1 VIM
37 nodular hidradenoma 10.2 MUC1 VIM
38 hidradenoma 10.2 MUC1 VIM
39 clear cell ependymoma 10.2 MUC1 VIM
40 hydromyelia 10.2 S100B VIM
41 endometrial mucinous adenocarcinoma 10.2 MUC1 VIM
42 bile duct adenoma 10.2 MUC1 VIM
43 bednar tumor 10.2 S100B VIM
44 biphasic synovial sarcoma 10.2 MUC1 VIM
45 primary hepatic neuroendocrine carcinoma 10.2 S100B VIM
46 clear cell meningioma 10.2 MUC1 VIM
47 meningeal melanocytoma 10.2 MUC1 S100B
48 melanotic neuroectodermal tumor 10.2 MUC1 VIM
49 gastric cardia carcinoma 10.2 KIT MUC1
50 desmoplastic small round cell tumor 10.2 MUC1 VIM

Graphical network of the top 20 diseases related to Perineurioma:



Diseases related to Perineurioma

Symptoms & Phenotypes for Perineurioma

GenomeRNAi Phenotypes related to Perineurioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased cell migration GR00055-A-1 8.92 ALK MUC1 NCAM1 VIM

MGI Mouse Phenotypes related to Perineurioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.43 ALK KIT NCAM1 S100B SLC2A1 VIM
2 nervous system MP:0003631 9.1 ALK DSP KIT NCAM1 SLC2A1 VIM

Drugs & Therapeutics for Perineurioma

Search Clinical Trials , NIH Clinical Center for Perineurioma

Genetic Tests for Perineurioma

Anatomical Context for Perineurioma

MalaCards organs/tissues related to Perineurioma:

41
Colon, Tongue, Skin, Lung, Pituitary, Smooth Muscle, Pineal

Publications for Perineurioma

Articles related to Perineurioma:

(show top 50) (show all 224)
# Title Authors Year
1
Left Supraclavicular Swelling: Sclerosing Perineurioma. ( 29531493 )
2018
2
Colonic perineurioma (benign fibroblastic polyp): case report and review of the literature. ( 29463272 )
2018
3
Perineurioma Treated With Mohs Micrographic Surgery. ( 29406485 )
2018
4
Intraosseous intraneural perineurioma derived from the inferior alveolar nerve with an abnormality of chromosome 22 and expression of the BCR-ABL fusion gene: report of a case and review of recent literature. ( 30213264 )
2018
5
Perineurioma of the sigmoid colon. ( 30262546 )
2018
6
A wolf in sheep's clothing: a benign perineurioma-like lesion that is not what it seems. ( 30498844 )
2018
7
Perineurioma of the colon: an uncommon tumor with an unusual location. Report of a case and review of the literature. ( 30546148 )
2018
8
Teaching NeuroImages: Sonographic detection of intraneural perineurioma in therapy-refractory carpal tunnel syndrome. ( 28265045 )
2017
9
Gastric perineurioma: clinicopathological characteristics. ( 28438389 )
2017
10
Soft Tissue Perineurioma in a Child With Neurofibromatosis Type 1: A Case Report and Review of the Literature. ( 28812461 )
2017
11
Whorling cellular perineurioma: A previously undescribed variant closely mimicking monophasic fibrous synovial sarcoma. ( 28325366 )
2017
12
Spontaneous spinal plexiform perineurioma in a juvenile chicken ( Gallus domesticus). ( 28381111 )
2017
13
Benign Cutaneous Peripheral Nerve Sheath Tumor with Hybrid Features: Report of Two Cases with Schwannoma/Perineurioma and Schwannoma/Neurofibroma Components. ( 29456994 )
2017
14
Anesthesia for a parturient with intraneural perineurioma: A case report. ( 29245354 )
2017
15
A Sclerosing Perineurioma With Collagen Rosette Formation: Benign Mimic of Low-Grade Fibromyxoid Sarcoma. ( 29172820 )
2017
16
Reticular Perineurioma of the Hand: Diagnosis and Treatment of a Rare Case of Hand Mass. ( 27955966 )
2016
17
Intratemporal Intraneural Perineurioma of the Facial Nerve. ( 27668794 )
2016
18
Fine-needle aspiration of soft tissue perineurioma: A comparative analysis of cytomorphology and immunohistochemistry with benign and malignant mimics. ( 27159449 )
2016
19
ALK Rearrangement and Overexpression in an Unusual Cutaneous Epithelioid Tumor With a Peculiar Whorled "Perineurioma-like" Growth Pattern: Epithelioid Fibrous Histiocytoma. ( 27438515 )
2016
20
Hybrid Epithelioid Schwannoma/Perineurioma. ( 26863063 )
2016
21
Pseudolipoblastic Perineurioma: An Unusual Morphological Variant of Perineurioma that May Simulate Liposarcoma. ( 27395366 )
2016
22
Diagnosis and outcome of childhood perineurioma. ( 27086131 )
2016
23
Nerve ultrasound and 3D-MR neurography suggestive of intraneural perineurioma. ( 27001989 )
2016
24
Gastric Perineurioma. ( 27125701 )
2016
25
Broadening the Anatomic Landscape of Sclerosing Perineurioma: A Series of 5 Cases in Nonacral Sites. ( 27845943 )
2016
26
Perineurioma of scalp in an infant: A case report with short review of literature. ( 26889289 )
2016
27
Oral perineurioma: clinicopathologic features from two cases and review of literature. ( 28034640 )
2016
28
Periprostatic Perineurioma, Description of a Case With Unusual Localization. ( 27335795 )
2016
29
Benign Cutaneous Plexiform Hybrid Tumor of Perineurioma and Cellular Neurothekeoma. ( 27138034 )
2016
30
Extra-acral cutaneous sclerosing perineurioma with CD34 fingerprint pattern. ( 28035704 )
2016
31
Case report: Intraneural perineurioma of the sciatic nerve in an adolescent - strategies for revealing the diagnosis. ( 27525083 )
2016
32
A hybrid tumor with schwannoma-perineurioma-neurofibroma morphology. ( 26147119 )
2015
33
Intraneural perineurioma of the digital nerve: a case report. ( 26115680 )
2015
34
Rapid Recurrence of a Benign Meningial Perineurioma. ( 26072455 )
2015
35
Malignant extraneural soft tissue perineurioma with striking microvascular proliferation. ( 25474519 )
2015
36
The almost-invisible perineurioma. ( 26323815 )
2015
37
Surgical removal of intraneural perineurioma arising in the brachial plexus using an interfascicular dissection technique. ( 24883285 )
2014
38
A Clinicopathologic and Immunohistochemical Study of 7 Cases of Sclerosing Perineurioma. ( 25051109 )
2014
39
Hybrid perineurioma-neurofibroma in a patient with neurofibromatosis type 1, clinically mimicking malignant peripheral nerve sheath tumor. ( 24751814 )
2014
40
ABL1 gene involvement within a complex three-way translocation (2;9;4) in perineurioma characterized by molecular cytogenetic methods. ( 25074247 )
2014
41
Soft tissue perineurioma of the tongue: report of a case and review of the literature. ( 24410763 )
2014
42
Intraneural malignant perineurioma: a case report and review of literature. ( 25120842 )
2014
43
Benign Cutaneous Biphasic Hybrid Tumor of Perineurioma and Cellular Neurothekeoma: A Case Report Expanding the Clinical and Histopathologic Features of a Recently Described Entity. ( 25229567 )
2014
44
Reverse adipofascial flap after resection of a malignant perineurioma of the forearm. ( 24992065 )
2014
45
Comparative Study of Soft Tissue Perineurioma And Meningioma Using A Five-Marker Immunohistochemical Panel. ( 24393170 )
2014
46
Intraneural Perineurioma of the Skin. ( 24999546 )
2014
47
Soft tissue perineurioma of the foot with 10q24 rearrangements: unique MRI features with histopathologic correlation. ( 24562506 )
2014
48
Primary pleural hybrid cellular schwannoma/perineurioma: a case report. ( 24998375 )
2014
49
Hybrid granular cell tumor/perineurioma. ( 25588629 )
2014
50
Perineurioma in the sigmoid colon diagnosed and treated by endoscopic resection. ( 26184017 )
2014

Variations for Perineurioma

Expression for Perineurioma

Search GEO for disease gene expression data for Perineurioma.

Pathways for Perineurioma

GO Terms for Perineurioma

Cellular components related to Perineurioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.5 ALK DSP KIT MUC1 NCAM1 SLC2A1
2 intercalated disc GO:0014704 9.16 DSP SLC2A1
3 cell-cell junction GO:0005911 8.8 DSP KIT SLC2A1

Biological processes related to Perineurioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.13 KIT MUC1 VIM
2 intermediate filament organization GO:0045109 8.62 DSP VIM

Molecular functions related to Perineurioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 8.96 DSP VIM
2 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.62 ALK KIT

Sources for Perineurioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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