MCID: PRN022
MIFTS: 37

Perineurioma

Categories: Rare diseases, Cancer diseases, Neuronal diseases

Aliases & Classifications for Perineurioma

MalaCards integrated aliases for Perineurioma:

Name: Perineurioma 12 53 55 15 73
Soft Tissue Perineurioma 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4697
MeSH 44 D018317
NCIt 50 C4973 C6912
SNOMED-CT 68 128795001 404036006

Summaries for Perineurioma

MalaCards based summary : Perineurioma, also known as soft tissue perineurioma, is related to sclerosing perineurioma and intraneural perineurioma. An important gene associated with Perineurioma is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways/superpathways are Neuroscience and Adhesion. Affiliated tissues include colon, tongue and kidney, and related phenotypes are behavior/neurological and nervous system

Related Diseases for Perineurioma

Diseases related to Perineurioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)
# Related Disease Score Top Affiliating Genes
1 sclerosing perineurioma 34.1 MUC1 S100B
2 intraneural perineurioma 33.7 MUC1 S100B SLC2A1
3 reticular perineurioma 33.4 KIT MUC1 S100B
4 localized hypertrophic neuropathy 31.1 MUC1 S100B
5 neurofibroma 30.8 KIT MUC1 S100B
6 neurofibromatosis, type i 30.0 KIT NCAM1
7 granular cell tumor 30.0 GFAP S100B VIM
8 sarcoma, synovial 29.8 KIT MUC1 VIM
9 malignant peripheral nerve sheath tumor 29.7 KIT MUC1 S100B VIM
10 gastrointestinal stromal tumor 29.7 KIT S100B VIM
11 fibrous histiocytoma 29.3 S100B VIM
12 cellular schwannoma 29.2 DSP S100B SLC2A1
13 neurilemmoma 29.2 GFAP KIT S100B VIM
14 extraneural perineurioma 12.1
15 malignant peripheral nerve sheath tumor with perineurial differentiation 11.0
16 non-functioning pituitary adenoma 10.7 MUC1 S100B
17 epithelioid malignant peripheral nerve sheath tumor 10.7 MUC1 S100B
18 sarcomatoid renal cell carcinoma 10.6 KIT MUC1
19 functioning pituitary adenoma 10.6 MUC1 S100B
20 mixed type thymoma 10.6 KIT S100B
21 meningeal melanocytoma 10.6 MUC1 S100B
22 malignant peritoneal mesothelioma 10.6 MUC1 VIM
23 papillary tumor of the pineal region 10.6 MUC1 VIM
24 nodular hidradenoma 10.6 MUC1 VIM
25 hydromyelia 10.6 S100B VIM
26 endometrial mucinous adenocarcinoma 10.6 MUC1 VIM
27 biphasic synovial sarcoma 10.6 MUC1 VIM
28 adenofibroma 10.6 MUC1 VIM
29 bednar tumor 10.6 S100B VIM
30 amelanotic melanoma 10.6 KIT S100B
31 primary hepatic neuroendocrine carcinoma 10.6 S100B VIM
32 hidradenoma 10.6 MUC1 VIM
33 desmoplastic small round cell tumor 10.5 MUC1 VIM
34 reticulum cell sarcoma 10.5 MUC1 VIM
35 sertoli cell tumor 10.5 MUC1 VIM
36 mucinous cystadenocarcinoma 10.5 MUC1 VIM
37 mesenchymal chondrosarcoma 10.5 MUC1 VIM
38 extraskeletal ewing sarcoma 10.5 MUC1 VIM
39 mast-cell sarcoma 10.5 KIT VIM
40 cutaneous leiomyosarcoma 10.5 GFAP MUC1
41 juvenile xanthogranuloma 10.5 S100B VIM
42 chondroid chordoma 10.5 MUC1 VIM
43 benign breast phyllodes tumor 10.5 KIT VIM
44 clear cell meningioma 10.5 GFAP MUC1
45 cutaneous fibrous histiocytoma 10.5 S100B VIM
46 rhabdoid cancer 10.5 MUC1 VIM
47 gemistocytic astrocytoma 10.5 GFAP S100B
48 senile angioma 10.5 KIT VIM
49 odontogenic myxoma 10.5 S100B VIM
50 dysembryoplastic neuroepithelial tumor 10.5 GFAP S100B

Graphical network of the top 20 diseases related to Perineurioma:



Diseases related to Perineurioma

Symptoms & Phenotypes for Perineurioma

MGI Mouse Phenotypes related to Perineurioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.43 GFAP KIT NCAM1 S100B SLC2A1 VIM
2 nervous system MP:0003631 9.1 DSP GFAP KIT NCAM1 SLC2A1 VIM

Drugs & Therapeutics for Perineurioma

Search Clinical Trials , NIH Clinical Center for Perineurioma

Genetic Tests for Perineurioma

Anatomical Context for Perineurioma

MalaCards organs/tissues related to Perineurioma:

41
Colon, Tongue, Kidney, Skin, Testes, Pancreas, Adipocyte

Publications for Perineurioma

Articles related to Perineurioma:

(show top 50) (show all 228)
# Title Authors Year
1
Left Supraclavicular Swelling: Sclerosing Perineurioma. ( 29531493 )
2018
2
Colonic perineurioma (benign fibroblastic polyp): case report and review of the literature. ( 29463272 )
2018
3
Perineurioma Treated With Mohs Micrographic Surgery. ( 29406485 )
2018
4
Teaching NeuroImages: Sonographic detection of intraneural perineurioma in therapy-refractory carpal tunnel syndrome. ( 28265045 )
2017
5
Gastric perineurioma: clinicopathological characteristics. ( 28438389 )
2017
6
Soft Tissue Perineurioma in a Child With Neurofibromatosis Type 1: A Case Report and Review of the Literature. ( 28812461 )
2017
7
Whorling cellular perineurioma: A previously undescribed variant closely mimicking monophasic fibrous synovial sarcoma. ( 28325366 )
2017
8
Spontaneous spinal plexiform perineurioma in a juvenile chicken ( Gallus domesticus). ( 28381111 )
2017
9
Benign Cutaneous Peripheral Nerve Sheath Tumor with Hybrid Features: Report of Two Cases with Schwannoma/Perineurioma and Schwannoma/Neurofibroma Components. ( 29456994 )
2017
10
Anesthesia for a parturient with intraneural perineurioma: A case report. ( 29245354 )
2017
11
Genomic analysis reveals frequent TRAF7 mutations in intraneural perineuriomas. ( 28019650 )
2017
12
A Sclerosing Perineurioma With Collagen Rosette Formation: Benign Mimic of Low-Grade Fibromyxoid Sarcoma. ( 29172820 )
2017
13
Reticular Perineurioma of the Hand: Diagnosis and Treatment of a Rare Case of Hand Mass. ( 27955966 )
2016
14
Intratemporal Intraneural Perineurioma of the Facial Nerve. ( 27668794 )
2016
15
Fine-needle aspiration of soft tissue perineurioma: A comparative analysis of cytomorphology and immunohistochemistry with benign and malignant mimics. ( 27159449 )
2016
16
ALK Rearrangement and Overexpression in an Unusual Cutaneous Epithelioid Tumor With a Peculiar Whorled "Perineurioma-like" Growth Pattern: Epithelioid Fibrous Histiocytoma. ( 27438515 )
2016
17
Hybrid Epithelioid Schwannoma/Perineurioma. ( 26863063 )
2016
18
Pseudolipoblastic Perineurioma: An Unusual Morphological Variant of Perineurioma that May Simulate Liposarcoma. ( 27395366 )
2016
19
Diagnosis and outcome of childhood perineurioma. ( 27086131 )
2016
20
Nerve ultrasound and 3D-MR neurography suggestive of intraneural perineurioma. ( 27001989 )
2016
21
Gastric Perineurioma. ( 27125701 )
2016
22
Broadening the Anatomic Landscape of Sclerosing Perineurioma: A Series of 5 Cases in Nonacral Sites. ( 27845943 )
2016
23
Perineurioma of scalp in an infant: A case report with short review of literature. ( 26889289 )
2016
24
Oral perineurioma: clinicopathologic features from two cases and review of literature. ( 28034640 )
2016
25
Periprostatic Perineurioma, Description of a Case With Unusual Localization. ( 27335795 )
2016
26
Benign Cutaneous Plexiform Hybrid Tumor of Perineurioma and Cellular Neurothekeoma. ( 27138034 )
2016
27
Extra-acral cutaneous sclerosing perineurioma with CD34 fingerprint pattern. ( 28035704 )
2016
28
Case report: Intraneural perineurioma of the sciatic nerve in an adolescent - strategies for revealing the diagnosis. ( 27525083 )
2016
29
A hybrid tumor with schwannoma-perineurioma-neurofibroma morphology. ( 26147119 )
2015
30
Intraneural perineurioma of the digital nerve: a case report. ( 26115680 )
2015
31
Rapid Recurrence of a Benign Meningial Perineurioma. ( 26072455 )
2015
32
Malignant extraneural soft tissue perineurioma with striking microvascular proliferation. ( 25474519 )
2015
33
The almost-invisible perineurioma. ( 26323815 )
2015
34
Surgical removal of intraneural perineurioma arising in the brachial plexus using an interfascicular dissection technique. ( 24883285 )
2014
35
A Clinicopathologic and Immunohistochemical Study of 7 Cases of Sclerosing Perineurioma. ( 25051109 )
2014
36
Hybrid perineurioma-neurofibroma in a patient with neurofibromatosis type 1, clinically mimicking malignant peripheral nerve sheath tumor. ( 24751814 )
2014
37
ABL1 gene involvement within a complex three-way translocation (2;9;4) in perineurioma characterized by molecular cytogenetic methods. ( 25074247 )
2014
38
Soft tissue perineurioma of the tongue: report of a case and review of the literature. ( 24410763 )
2014
39
Intraneural malignant perineurioma: a case report and review of literature. ( 25120842 )
2014
40
Benign Cutaneous Biphasic Hybrid Tumor of Perineurioma and Cellular Neurothekeoma: A Case Report Expanding the Clinical and Histopathologic Features of a Recently Described Entity. ( 25229567 )
2014
41
Reverse adipofascial flap after resection of a malignant perineurioma of the forearm. ( 24992065 )
2014
42
Comparative Study of Soft Tissue Perineurioma And Meningioma Using A Five-Marker Immunohistochemical Panel. ( 24393170 )
2014
43
Intraneural Perineurioma of the Skin. ( 24999546 )
2014
44
Soft tissue perineurioma of the foot with 10q24 rearrangements: unique MRI features with histopathologic correlation. ( 24562506 )
2014
45
Primary pleural hybrid cellular schwannoma/perineurioma: a case report. ( 24998375 )
2014
46
Hybrid granular cell tumor/perineurioma. ( 25588629 )
2014
47
Perineurioma in the sigmoid colon diagnosed and treated by endoscopic resection. ( 26184017 )
2014
48
Myxoid perineurioma in a transplanted kidney. ( 24507070 )
2014
49
Sclerosing perineurioma: case report and literature review. ( 24945652 )
2014
50
Intraneural perineurioma affecting multiple nerves: a case report and literature review. ( 25031759 )
2014

Variations for Perineurioma

Expression for Perineurioma

Search GEO for disease gene expression data for Perineurioma.

Pathways for Perineurioma

GO Terms for Perineurioma

Cellular components related to Perineurioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intercalated disc GO:0014704 9.16 DSP SLC2A1
2 intermediate filament GO:0005882 9.13 DSP GFAP VIM
3 cell-cell junction GO:0005911 8.8 DSP KIT SLC2A1

Biological processes related to Perineurioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.54 KIT MUC1 VIM
2 long-term synaptic potentiation GO:0060291 9.32 GFAP S100B
3 astrocyte development GO:0014002 9.26 GFAP VIM
4 Bergmann glial cell differentiation GO:0060020 9.16 GFAP VIM
5 intermediate filament-based process GO:0045103 8.96 GFAP VIM
6 intermediate filament organization GO:0045109 8.8 DSP GFAP VIM

Molecular functions related to Perineurioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 9.16 DSP VIM
2 structural molecule activity GO:0005198 9.13 DSP GFAP VIM
3 structural constituent of cytoskeleton GO:0005200 8.8 DSP GFAP VIM

Sources for Perineurioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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